Also known as ERp57
A molecular chaperone that plays a crucial role in the endoplasmic reticulum (ER) stress response.
ERp57 is often overexpressed, which can contribute to tumor growth and survival.
ERp57 can promote cancer cell proliferation, migration, and invasion by regulating various signaling pathways, including the PI3K/AKT and MAPK/ERK pathways. Additionally, ERp57 can also inhibit apoptosis (programmed cell death) in cancer cells, which can contribute to tumor progression.
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