Interferon Regulatory Factor 3 (IRF3) is a transcription factor that plays a crucial role in the regulation of immune responses, particularly in the context of viral infections and cancer. IRF3 is a key component of the innate immune system, which is the first line of defense against pathogens.
IRF3 has been shown to have both tumor-suppressive and tumor-promoting functions, depending on the type of cancer and the specific cellular context.
Generally, there is lower expression of IRF3 in cancer and is associated with worse prognosis in many cancers, indicating its potential role as a tumor suppressor.
(Will delete Record if Target field = "Delete") Home