LOX-1 (Lectin-like oxidized low-density lipoprotein receptor 1) is a protein that has been implicated in various diseases, including cancer. Research has shown that LOX-1 is overexpressed in several types of cancer, including breast, lung, colon, and prostate cancer.
LOX-1 is involved in the regulation of cell proliferation, apoptosis (cell death), and angiogenesis (the formation of new blood vessels). In cancer, LOX-1 can promote tumor growth and metastasis by:
Enhancing cell proliferation and survival
Inhibiting apoptosis
Promoting angiogenesis
Facilitating the migration and invasion of cancer cells
Studies have also shown that LOX-1 can interact with other molecules involved in cancer progression, such as vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs).
Inhibiting LOX-1 has been proposed as a potential therapeutic strategy for cancer treatment.
(Will delete Record if Target field = "Delete") Home