EGF is a protein that acts as a ligand, binding to its receptor, EGFR. It is a potent mitogen, stimulating cell proliferation and differentiation. EGF is involved in various physiological processes, including wound healing, embryonic development, and tissue regeneration.
EGF is overexpressed: breast, CRC, GBM, lung, ovarian.
EGF is decreased: Prostate, Pancreatic.
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