StAR (Steroidogenic Acute Regulatory protein) is a protein that plays a crucial role in the regulation of steroid hormone biosynthesis. It is involved in the transfer of cholesterol into the mitochondria, where it is converted into pregnenolone, the precursor to all steroid hormones.
StAR is overexpressed in various types of cancer, including breast, prostate, and ovarian cancer. This overexpression is often associated with increased steroid hormone production, which can promote tumor growth and progression.
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