Lysosomal proteolysis is a cellular process that involves the degradation of proteins within lysosomes, which are membrane-bound organelles that contain digestive enzymes.
Lysosomal proteolysis is generally considered protumorigenic. The degradation of extracellular matrix components and the release of proteolytic enzymes can facilitate tumor cell invasion and metastasis. Additionally, lysosomal proteolysis can contribute to the activation of signaling pathways that promote cell survival and proliferation.
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