LAMP-2 (Lysosome-Associated Membrane Protein 2) is a protein that plays a crucial role in the function and maintenance of lysosomes, which are organelles responsible for cellular digestion and recycling.
LAMP-2 is involved in the regulation of autophagy, a process by which cells recycle damaged or dysfunctional components. Cancer cells often exploit autophagy to promote their survival and growth.
LAMP-2 is overexpressed in various types of cancer, including breast, lung, colon, and prostate cancer.
High LAMP-2 expression is correlated with poor prognosis, including reduced overall survival and increased risk of recurrence.
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