Hormones such as glucagon and cortisol can stimulate gluconeogenesis. In cancer, the dysregulation of these hormones can contribute to altered glucose metabolism.
Cortisol is a steroid hormone produced by the adrenal glands, primarily in response to stress and low blood glucose levels.
Elevated cortisol levels have been observed in patients with cancer.
High cortisol levels may be associated with worse prognosis, increased tumor aggressiveness, and higher rates of metastasis. Chronic stress and elevated cortisol can influence tumor microenvironments.
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