ENO2 (Enolase 2) is an enzyme that plays a crucial role in the glycolytic pathway, which is often upregulated in cancer cells, and related to poor prognosis.
ENO2 (Enolase 2) is a cytoplasmic enzyme that plays a crucial role in the glycolytic pathway, as I mentioned earlier. It is a key enzyme in the conversion of 2-phosphoglycerate to enolpyruvate, which is then converted to pyruvate.
ENOX2 (Enox2), on the other hand, is a cell surface enzyme that is also known as Cytosolic Enolase 2 or ENO2 variant. ENOX2 is a truncated form of ENO2 that lacks the first 96 amino acids of the full-length ENO2 protein. Despite this difference, ENOX2 retains enolase activity and is also involved in the glycolytic pathway.
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