MCT4 is a member of the monocarboxylate transporter family, which plays a crucial role in the transport of lactate, pyruvate, and other monocarboxylates across cell membranes. In cancer, MCT4 is often upregulated to support the increased demand for lactate and pyruvate, which are essential for cancer cell metabolism.
High expression of MCT4 is often associated with poor prognosis in various cancers, including breast, lung, colorectal, prostate, pancreatic, ovarian, and glioblastoma.
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