v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
KRAS (Kirsten rat sarcoma viral oncogene homolog) is a gene that encodes a protein involved in cell signaling pathways that control cell growth and division. Mutations in the KRAS gene are among the most common genetic alterations found in various types of cancer, particularly pancreatic, colorectal, and lung cancers.
Mutations in the KRAS gene lead to the production of a hyperactive KRAS protein.
Cancers with KRAS mutations are often more aggressive and associated with poorer prognosis.