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tid		Target	BRCA1	Cancers General Effect on Target

Name	BReast CAncer gene 1
Source	CGL-Driver Genes
Type	TSG

BReast CAncer gene 1

BRCA1 and BRCA2 are tumor suppressor genes, which, when they function normally, keep tumors from forming.
BRCA1 mutations are associated with an increased risk for:
Breast cancer, including an aggressive form called Triple Negative Breast Cancer
Ovarian cancer
Pancreatic cancer
Prostate cancer
BRCA1/BRCA2 are used as clinical biomarker for PARP inhibitor use.

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