TumVol Cancer Research Results

TumVol, Tumor Volume: Click to Expand ⟱
Source:
Type:
Tumor Volume
Scientific Papers found: Click to Expand⟱
6463- 1,8-Cin,    Antitumor effect of 1, 8-cineole against colon cancer
- vitro+vivo, Colon, HCT116
TumCP↓, Apoptosis↑, survivin↓, Akt↓, p38↑, cl‑PARP↑, cl‑Casp3↑, TumVol↓,
5263- 3BP,  CET,    3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis
- in-vitro, CRC, DLD1 - NA, NA, HCT116
eff↑, Ferroptosis↓, TumAuto↑, Apoptosis↑, FOXO3↑, AMPKα↑, p‑Beclin-1/ATG6↑, HK2↓, ATP↓, ROS↑, Dose↝, TumVol↓, TumW↓, xCT/SLC7A11↑, GSH↓, eff↓, MDA↑,
5975- AgNPs,  PDT,  CDT,  RF,    Recent Advances in the Application of Silver Nanoparticles for Enhancing Phototherapy Outcomes
- Review, Var, NA - Review, BPH, NA
ROS↑, EPR↓, eff↑, Bacteria↓, eff↑, eff↑, TumVol↓,
4394- AgNPs,    Silver nanoparticles provoke apoptosis of Dalton's ascites lymphoma in vivo by mitochondria dependent and independent pathways
- in-vivo, lymphoma, NA
OS↑, TumVol↓, Weight↑, AntiTum↑, Apoptosis↑, mtDam↑,
4431- AgNPs,  doxoR,    Oxidative Stress-Induced Silver Nano-Carriers for Chemotherapy
- in-vitro, BC, 4T1 - in-vivo, BC, 4T1 - in-vitro, Nor, 3T3
AntiCan↑, ROS↑, TumVol↓, EPR↑, selectivity↑, ChemoSen↑,
4361- AgNPs,  GoldNP,    Biocompatible silver, gold and silver/gold alloy nanoparticles for enhanced cancer therapy: in vitro and in vivo perspectives
- in-vivo, Liver, HepG2
TumCD↑, TumVol↓, *toxicity↝, hepatoP↑,
4363- AgNPs,    Immunomodulatory properties of silver nanoparticles contribute to anticancer strategy for murine fibrosarcoma
- in-vivo, fibroS, NA
TumVol↓, TNF-α↓, IL6↓, IL1β↓, *toxicity↝, TumCG↓, selectivity↑, selectivity↑, Weight↑, ROS↑, NO↑,
312- AgNPs,  wortm,    Inhibition of autophagy enhances the anticancer activity of silver nanoparticles
- vitro+vivo, Cerv, HeLa
APA↑, p62↓, PIK3CA↑, TumVol↓, TumAuto↑, eff↑,
362- AgNPs,    Comparative and Mechanistic Study on the Anticancer Activity of Quinacrine-Based Silver and Gold Hybrid Nanoparticles in Head and Neck Cancer
- vitro+vivo, SCC, SCC9
DNAdam↑, TumVol↓,
378- AgNPs,    Antitumor efficacy of silver nanoparticles reduced with β-D-glucose as neoadjuvant therapy to prevent tumor relapse in a mouse model of breast cancer
- ex-vivo, BC, 4T1
TumVol↓, TumMeta↓, Ki-67↓,
390- AgNPs,    Anti-cancerous effect of albumin coated silver nanoparticles on MDA-MB 231 human breast cancer cell line
- in-vitro, BC, MDA-MB-231 - in-vivo, BC, NA
ROS↑, TumVol↓,
5342- Ajoene,    The garlic-derived organosulfur component ajoene decreases basal cell carcinoma tumor size by inducing apoptosis
- in-vivo, BCC, NA
TumVol↓, Bcl-2↓, Apoptosis↑,
546- AL,    Effects of garlic intake on cancer: a systematic review of randomized clinical trials and cohort studies
- Review, NA, NA
Risk↓, TumVol↓,
1069- AL,    Allicin promotes autophagy and ferroptosis in esophageal squamous cell carcinoma by activating AMPK/mTOR signaling
- vitro+vivo, ESCC, TE1 - vitro+vivo, ESCC, KYSE-510 - in-vitro, Nor, Het-1A
TumCP↓, LC3‑Ⅱ/LC3‑Ⅰ↑, p62↓, p‑AMPK↑, mTOR↓, TumAuto↑, NCOA4↑, MDA↑, Iron↑, TumW↓, TumVol↓, ATG5↑, ATG7↑, TfR1/CD71↓, FTH1↓, ROS↑, Iron↑, Ferroptosis↑, *toxicity↓,
271- ALA,  VitC,  LDN,    The Long-Term Survival of a Patient With Stage IV Renal Cell Carcinoma Following an Integrative Treatment Approach Including the Intravenous α-Lipoic Acid/Low-Dose Naltrexone Protocol
OS↑, Weight↑, TumVol↓,
177- Api,    Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21WAF1/CIP1 expression
- in-vitro, BC, MDA-MB-231
Cyc↓, CycB/CCNB1↓, CDK1↓, P21↑, PCNA↝, HDAC↓, TumCP↓, TumCCA↑, ac‑H3↑, TumW↓, TumVol↓,
2319- Api,    Apigenin sensitizes radiotherapy of mouse subcutaneous glioma through attenuations of cell stemness and DNA damage repair by inhibiting NF-κB/HIF-1α-mediated glycolysis
- in-vitro, GBM, NA
Glycolysis↓, NF-kB↓, p65↓, Hif1a↓, GLUT1↓, GLUT3↓, PKM2↓, RadioS↑, TumVol↓, TumW↓,
1546- Api,    Apigenin in Cancer Prevention and Therapy: A Systematic Review and Meta-Analysis of Animal Models
- Review, NA, NA
TumVol↓, TumW↓, AntiCan↑, Apoptosis↑, TumCCA↑,
1553- Api,    Role of Apigenin in Cancer Prevention via the Induction of Apoptosis and Autophagy
- Review, NA, NA
Dose∅, TumVol↓, Dose∅, COX2/PTGS2↓, Hif1a↓, TumCCA↑, P53↑, P21↑, Casp3↑, DNAdam↑, TumAuto↝,
1564- Api,    Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation
- in-vitro, Pca, 22Rv1 - in-vivo, NA, NA
MDM2↓, NF-kB↓, p65↓, P21↑, ROS↑, GSH↓, MMP↓, Cyt‑c↑, Apoptosis↑, P53↑, eff↓, Bcl-xL↓, Bcl-2↓, BAX↑, Casp↑, TumCG↓, TumVol↓, TumW↓,
3391- ART/DHA,    Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug
- Review, Var, NA
TumCP↓, TumMeta↓, angioG↓, TumVol↓, BioAv↓, Half-Life↓, BioAv↑, eff↑, eff↓, ROS↑, selectivity↑, TumCCA↑, survivin↓, BAX↑, Casp3↓, Casp8↑, Casp9↑, CDC25↓, CycB/CCNB1↓, NF-kB↓, cycD1/CCND1↓, cycE/CCNE↓, E2Fs↓, P21↑, p27/CDKN1B↑, ADP:ATP↑, MDM2↓, VEGF↓, IL8↓, COX2/PTGS2↓, MMP9↓, ER Stress↓, cMyc↓, GRP78/BiP↑, DNAdam↑, AP-1↓, MMP2↓, PKCδ↓, Raf↓, ERK↓, JNK↓, PCNA↓, CDK2↓, CDK4↓, TOP2↓, uPA↓, MMP7↓, TIMP2↑, Cdc42↑, E-cadherin↑,
1179- Ash,    Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity
- in-vitro, CRC, HCT116 - in-vivo, NA, NA
TumCP↓, TumCMig↓, STAT3↓, TumVol↓, TumW↓,
1177- Ash,    Withaferin A downregulates COX-2/NF-κB signaling and modulates MMP-2/9 in experimental endometriosis
- in-vivo, EC, NA
TumVol↓, MMP2↓, MMP9↓, NF-kB↓, COX2/PTGS2↓, NO↓, IL1β↓, IL6↓,
1176- Ash,    Metabolic Alterations in Mammary Cancer Prevention by Withaferin A in a Clinically Relevant Mouse Model
- in-vivo, NA, NA
TumVol↓, Apoptosis↑, Glycolysis↓, PKM2↓, PGK1↓, ALDOAiso2↓,
5499- Ba,    Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo
- vitro+vivo, Lung, H460 - vitro+vivo, Lung, A549
TumCP↓, Apoptosis↑, F-actin↓, TumVol↓, OS↑, 12LOX↓, VEGF↓, angioG↓,
2599- Ba,    Baicalein induces apoptosis and autophagy of breast cancer cells via inhibiting PI3K/AKT pathway in vivo and vitro
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
TumCP↓, Apoptosis↑, p‑Akt↓, p‑mTOR↓, NF-kB↓, p‑IKKα↓, IKKα↑, PI3K↓, MMP↓, TumAuto↑, TumVol↓, TumW↓,
5551- BBM,    Berbamine Suppresses the Progression of Bladder Cancer by Modulating the ROS/NF-κB Axis
- vitro+vivo, Bladder, NA
tumCV↓, TumCP↓, TumCCA↑, P21↑, p27/CDKN1B↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, EMT↓, TumMeta↓, p65↓, p‑p65↓, IKKα↓, NF-kB↑, ROS↑, NRF2↓, HO-1↓, SOD2↓, GPx1↓, Bax:Bcl2↑, TumVol↓,
940- BBR,    Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression
- vitro+vivo, PC, PANC1 - in-vivo, PC, MIA PaCa-2
LDHA↓, lactateProd↓, AMPKα↓, TumVol↓, Ki-67↓,
5176- BBR,    Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice
- vitro+vivo, CRC, HCT116 - in-vitro, CRC, SW480 - in-vitro, CRC, LoVo
TumVol↓, Ki-67↓, COX2/PTGS2↓, AMPK↑, mTOR↓, NF-kB↓, cycD1/CCND1↓, survivin↓, P53↑, cl‑Casp3↑, TumCP↓, Inflam↓, COX2/PTGS2↓, ACC↑,
6518- BCP,    beta-Caryophyllene Induces Apoptosis and Inhibits Angiogenesis in Colorectal Cancer Models
- vitro+vivo, CRC, HCT116
angioG↓, VEGF↓, TumVol↓, HSP60/HSPD1↓, HTRA↓, survivin↓, XIAP↓, P21↑, TumCP↓, TumCMig↓, TumCG↓, Dose↝,
6496- BCP,    β-Caryophyllene Induces Apoptosis and Inhibits Angiogenesis in Colorectal Cancer Models
- vitro+vivo, CRC, HCT116 - in-vitro, Nor, HUVECs
angioG↓, VEGF↓, TumVol↓, Apoptosis↑, HSP60/HSPD1↓, HTRA↓, survivin↓, XIAP↓, P21↑, *toxicity↓, *neuroP↑, *ROS↓, *COX2/PTGS2↓, *Inflam↓, *cardioP↑, AntiCan↑, ChemoSen↑, ROS↑, MMP↑, Bax:Bcl2↑, TumCG↓,
2717- BetA,    Betulinic Acid Induces ROS-Dependent Apoptosis and S-Phase Arrest by Inhibiting the NF-κB Pathway in Human Multiple Myeloma
- in-vitro, Melanoma, U266 - in-vivo, Melanoma, NA - in-vitro, Melanoma, RPMI-8226
Apoptosis↑, TumCCA↑, MMP↓, ROS↑, eff↓, NF-kB↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, cl‑PARP1↑, MDA↑, SOD↓, SOD2↓, GCLM↓, GSTA1↓, FTH1↓, GSTs↓, TumVol↓,
2733- BetA,    Betulinic Acid Inhibits Cell Proliferation in Human Oral Squamous Cell Carcinoma via Modulating ROS-Regulated p53 Signaling
- in-vitro, Oral, KB - in-vivo, NA, NA
TumCP↓, TumVol↓, mt-Apoptosis↑, Casp3↑, Casp9↑, BAX↑, Bcl-2↑, OCR↓, TumCCA↑, ROS↑, eff↓, P53↑, STAT3↓, cycD1/CCND1↑,
2746- BetA,    Betulinic acid induces apoptosis and inhibits metastasis of human colorectal cancer cells in vitro and in vivo
- in-vitro, CRC, HCT116 - in-vivo, CRC, NA
TumCG↓, BAX↑, Bcl-2↓, ROS↑, MMP↓, TIMP2↑, TumVol↓,
5692- BJ,    Seed oil of Brucea javanica induces apoptosis through the PI3K/Akt signaling pathway in acute lymphocytic leukemia Jurkat cells
- vitro+vivo, AML, NA
Apoptosis↑, Akt↓, P53↑, FOXO1↑, GSK‐3β↑, TumVol↓, QoL↑, BBB↑, OS↑, Dose↝, MMP↓, ROS↑, XIAP↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, TumCCA↑,
5683- BML,    Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumor-initiation triggering mitochondrial death pathway
- in-vitro, NA, NA
COX2/PTGS2↓, MAPK↓, NF-kB↓, TumMeta↓, P53↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, MAPK↓, ERK↓, Akt↓, TumVol↓,
5658- BNL,    Natural borneol is a novel chemosensitizer that enhances temozolomide-induced anticancer efficiency against human glioma by triggering mitochondrial dysfunction and reactive oxide species-mediated oxidative damage
- vitro+vivo, GBM, U251
ChemoSen↑, mt-Apoptosis↑, Casp↑, DNAdam↑, ROS↑, angioG↓, BBB↑, EPR↑, TumVol↓, TumW↓, BioEnh↑,
3518- Bor,    Boron Report
- Review, Var, NA - Review, AD, NA
Risk↓, serineP↓, PSA↓, TumVol↓, IGF-1↓, *Mag↑, *Calcium↑, *VitD↑, *COX2/PTGS2↓, *5LO↓, *PGE2↓, *NF-kB↓, *cognitive↑,
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,
746- Bor,    Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope
- Review, NA, NA
eff↑, *toxicity↓, ROS↑, LAT↓, AntiCan↑, AR↓, PSMB5↓, IGF-1↓, PSA↓, TumVol↓, eff↑, Rho↓, Cdc42↓, Ca+2↓, eff↑,
706- Bor,    Boron supplementation inhibits the growth and local expression of IGF-1 in human prostate adenocarcinoma (LNCaP) tumors in nude mice
- in-vivo, Pca, LNCaP
TumVol↓, IGF-1↓, PSA↓,
4624- Bor,  VitD3,    Boron as a Medicinal Ingredient in Oral Natural Health Products
- Review, Pca, NA
*Half-Life↝, *eff↑, PSA↓, TumVol↓, IGF-1↓, *memory↓, *motorD↓,
1169- Bos,    Boswellic Acid Inhibits Growth and Metastasis of Human Colorectal Cancer in Orthotopic Mouse Model By Downregulating Inflammatory, Proliferative, Invasive, and Angiogenic Biomarkers
- in-vivo, CRC, NA
TumCG↓, TumVol↓, Weight∅, ascitic↓, TumMeta↓, Ki-67↓, CD31/PECAM-1↓, NF-kB↓, COX2/PTGS2↓, Bcl-2↓, Bcl-xL↓, IAP1↓, survivin↓, cycD1/CCND1↓, ICAM-1↓, MMP9↓, CXCR4↓, VEGF↓,
6555- BSB,    Cyclodextrin Conjugated α-Bisabolol Suppresses FAK Phosphorylation and Induces Apoptosis in Pancreatic Cancer
- vitro+vivo, PC, NA
TumCP↓, TumCI↓, p‑FAK↓, TumVol↓, Ki-67↓,
1230- CA,  Caff,    Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - Human, NA, NA
TumVol↓, TumCG↓, ER(estro)↓, cycD1/CCND1↓, IGF-1R↓, p‑Akt↓,
5749- CA,  Z,  Rad,    Antitumor and Radiosensitizing Effects of Zinc Oxide-Caffeic Acid Nanoparticles against Solid Ehrlich Carcinoma in Female Mice
- vitro+vivo, BC, MCF7 - NA, Liver, HepG2
RadioS↑, TumVol↓, Bcl-2↓, NF-kB↓, VCAM-1↓, ERK↓, DNAdam↑, TumCCA↑,
2013- CAP,    Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cells
- in-vitro, Pca, PC3 - in-vitro, Pca, LNCaP - in-vitro, Pca, DU145 - in-vivo, NA, NA
TumCP↓, P53↑, P21↑, BAX↑, PSA↓, AR↓, NF-kB↓, Proteasome↓, TumVol↓, eff∅,
5886- CAR,    Inhibition of TRPM7 with carvacrol suppresses glioblastoma functions in vivo
- in-vivo, GBM, U87MG - in-vivo, GBM, U251
TRPM7↓, TumVol↓, p‑Akt↓, p‑GSK‐3β↑, Dose↝,
1103- CBD,    Cannabidiol inhibits invasion and metastasis in colorectal cancer cells by reversing epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway
- vitro+vivo, NA, NA
Apoptosis↑, TumCP↓, TumCMig↓, TumMeta↓, EMT↓, E-cadherin↑, N-cadherin↓, Snail↓, Vim↓, Hif1a↓, Wnt/(β-catenin)↓, AXIN1↑, TumVol↓, TumW↓,
5940- Cela,    Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway
- in-vivo, Pca, PC3
Dose↝, TumVol↓, TumW↓, angioG↓, VEGF↓, TumCMig↓, TumCP↓, TumCI↓, Akt↓, mTOR↓, P70S6K↓,

Showing Research Papers: 1 to 50 of 204
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 204

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

CD47↓, 1,   FBXO5/EMI1↓, 1,   HSP60/HSPD1↓, 2,   HTRA↓, 2,   IL7↓, 1,   ILK↓, 1,   IRes↓, 1,   IRF1↑, 1,   LIFR/CD118↓, 1,   miR-124-3p↓, 1,   miR-199↓, 1,   miR-375↑, 1,   PFS↑, 1,   PLA2↓, 1,   SALL4↓, 1,   TFE3↑, 1,   WDR72↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 3,   Catalase↓, 2,   Catalase↑, 1,   compI↓, 1,   Fenton↑, 2,   Ferroptosis↓, 1,   Ferroptosis↑, 6,   GCLM↓, 1,   GPx↑, 1,   GPx1↓, 1,   GPx4↓, 4,   GSH↓, 7,   GSH/GSSG↓, 1,   GSTA1↓, 1,   GSTs↓, 1,   GSTZ1↓, 1,   H2O2↑, 1,   HO-1↓, 2,   hyperG↓, 1,   ICD↑, 2,   Iron↑, 4,   Iron∅, 1,   i-Iron↑, 1,   lipid-P↑, 3,   MDA↑, 4,   NRF2↓, 2,   NRF2↝, 1,   OXPHOS↑, 2,   mt-OXPHOS↑, 1,   ROS↓, 2,   ROS↑, 50,   mt-ROS↑, 3,   SOD↓, 2,   SOD↑, 1,   SOD2↓, 2,   SOD2↑, 2,   TrxR1↓, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

FTH1↓, 2,   KLF5↓, 1,   NCOA4↑, 1,   TfR1/CD71↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 1,   AIF↑, 1,   ATP↓, 3,   ATP↝, 1,   CDC25↓, 3,   ETC↓, 1,   mitResp↓, 1,   MMP↓, 21,   MMP↑, 1,   MPT↑, 1,   mtDam↑, 3,   OCR↓, 2,   OCR↑, 2,   PGC-1α↑, 2,   Raf↓, 1,   XIAP↓, 6,   XIAP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   ACC↑, 1,   ALAT↓, 2,   ALAT↑, 1,   ALDOAiso2↓, 1,   AMPK↓, 1,   AMPK↑, 2,   p‑AMPK↑, 2,   ATG7↑, 1,   cMyc↓, 4,   ECAR↓, 1,   GlucoseCon↓, 4,   Glycolysis↓, 9,   Glycolysis↑, 1,   HK2↓, 6,   HMG-CoA↓, 1,   IR↓, 1,   lactateProd↓, 7,   LAT↓, 1,   LDH↑, 2,   LDHA↓, 2,   lipoGen↓, 1,   NAD↓, 1,   PDH↑, 1,   PDK1 / PDPK1↓, 1,   PDKs↓, 1,   PFK↓, 1,   PGK1↓, 1,   p‑PI3k/Akt/mTOR↓, 1,   PIK3CA↑, 1,   PKM2↓, 6,   PSMB5↓, 1,   SCD1↓, 1,   SIRT1↓, 1,   TS↓, 1,   Warburg↓, 4,  

Cell Death(tgid=5) ⓘ

Akt↓, 20,   Akt↑, 3,   p‑Akt↓, 9,   Apoptosis?, 1,   Apoptosis↓, 1,   Apoptosis↑, 70,   mt-Apoptosis↑, 2,   ASK1↑, 1,   BAD↓, 1,   Bak↑, 1,   BAX↑, 27,   Bax:Bcl2↑, 5,   Bcl-2↓, 37,   Bcl-2↑, 1,   Bcl-xL↓, 11,   BIM↑, 1,   Casp↑, 6,   proCasp↑, 1,   Casp1↑, 1,   Casp12↑, 1,   Casp3?, 1,   Casp3↓, 1,   Casp3↑, 29,   cl‑Casp3↑, 14,   proCasp3↑, 1,   Casp7?, 1,   Casp7↑, 2,   cl‑Casp7↑, 1,   Casp8↑, 6,   cl‑Casp8↑, 3,   Casp9?, 1,   Casp9↑, 13,   cl‑Casp9↑, 4,   cFLIP↓, 1,   Cyt‑c↓, 1,   Cyt‑c↑, 9,   DR5↑, 1,   Endon↑, 1,   FasL↑, 1,   Ferroptosis↓, 1,   Ferroptosis↑, 6,   GSDMD↑, 1,   GSDME↑, 1,   Hippo↓, 1,   hTERT/TERT↓, 1,   IAP1↓, 2,   IAP2/BIRC3↓, 1,   iNOS↓, 2,   JNK↓, 1,   JNK↑, 1,   p‑JNK↑, 3,   lysoMP↓, 1,   lysoMP↑, 1,   MAPK↓, 5,   MAPK↑, 1,   Mcl-1↓, 5,   MDM2↓, 2,   miR-497↑, 1,   necrosis↑, 2,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 4,   p38↑, 1,   p‑p38↑, 4,   Proteasome↓, 1,   Pyro↑, 2,   survivin↓, 18,   TumCD↑, 13,   YAP/TEAD↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

AMPKα↓, 1,   AMPKα↑, 1,   HER2/EBBR2↓, 1,   p‑p70S6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

EZH2↓, 1,   ac‑H3↑, 1,   ac‑H4↑, 1,   KCNQ1OT1↓, 1,   other↓, 2,   other↝, 9,   SD↑, 1,   tumCV↓, 23,   tumCV↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 2,   eIF2α↑, 1,   ER Stress↓, 1,   ER Stress↑, 2,   GRP78/BiP↑, 3,   HSP70/HSPA5↓, 2,   HSP90↓, 2,   PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

APA↑, 1,   ATG5↑, 2,   ATG5↝, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↝, 1,   p‑Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3B↑, 1,   LC3B-II↓, 1,   LC3B-II↑, 1,   LC3I↑, 1,   LC3II↑, 1,   p62↓, 3,   p62↑, 2,   TumAuto↓, 1,   TumAuto↑, 13,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 12,   DNArepair↓, 1,   DNMT1↓, 1,   NKX3.1↓, 1,   P53↑, 17,   i-P53↓, 1,   PARP↓, 1,   PARP↑, 1,   cl‑PARP↑, 18,   PARP1↑, 1,   cl‑PARP1↑, 3,   PCNA↓, 7,   PCNA↝, 1,   γH2AX↑, 2,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 4,   CDK2↓, 6,   CDK4↓, 7,   CDK4↑, 2,   Cyc↓, 2,   cycA1/CCNA1↓, 3,   CycB/CCNB1↓, 6,   cycD1/CCND1↓, 20,   cycD1/CCND1↑, 1,   cycE/CCNE↓, 3,   cycE1↓, 1,   E2Fs↓, 2,   mitA↓, 1,   mitA↑, 1,   P21↓, 2,   P21↑, 14,   TumCCA↑, 42,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑4E-BP1↓, 1,   ALDH↓, 4,   AR-FL↓, 1,   AR-V7↑, 1,   AXIN1↑, 1,   CD133↓, 2,   CD24↓, 1,   CD44↓, 5,   CSCs↓, 9,   CSCsMark↓, 1,   Diff↑, 1,   EMT↓, 12,   EP2↓, 1,   EpCAM↓, 2,   ERK↓, 4,   p‑ERK↓, 7,   p‑ERK↑, 1,   FGF↓, 2,   FOXO1↑, 1,   FOXO3↑, 1,   Gli1↓, 1,   GSK‐3β↓, 1,   GSK‐3β↑, 1,   p‑GSK‐3β↓, 1,   p‑GSK‐3β↑, 2,   HDAC↓, 6,   HDAC1↓, 2,   HDAC2↓, 2,   HDAC3↓, 1,   HH↓, 2,   HH∅, 1,   IGF-1↓, 5,   IGF-1R↓, 1,   LGR5↓, 1,   LRP6↓, 1,   p‑LRP6↓, 1,   mTOR↓, 8,   mTOR↑, 3,   p‑mTOR↓, 3,   mTORC1↓, 1,   Nanog↓, 2,   NOTCH1↓, 2,   NOTCH3↓, 1,   OCT4↓, 5,   P70S6K↓, 1,   PI3K↓, 17,   PI3K↑, 2,   p‑PI3K↓, 1,   PTEN↓, 1,   PTEN↑, 2,   SCF↓, 1,   Shh↓, 1,   SHP1↑, 1,   Smo↓, 1,   SOX2↓, 2,   c-Src↓, 1,   STAT↓, 1,   STAT3↓, 13,   p‑STAT3↓, 3,   p‑STAT3↑, 2,   i-STAT3↓, 1,   STAT4↑, 1,   STAT5↓, 1,   TCF↝, 1,   TK1↓, 1,   TOP2↓, 2,   TRPM7↓, 1,   TumCG?, 1,   TumCG↓, 28,   VGSC↑, 1,   Wnt↓, 4,   Wnt/(β-catenin)↓, 2,  

Migration(tgid=13) ⓘ

AP-1↓, 1,   Ca+2↓, 1,   Ca+2↑, 9,   Ca+2↝, 1,   CAFs/TAFs↓, 1,   CD31/PECAM-1↓, 2,   Cdc42↓, 1,   Cdc42↑, 1,   CDKN1C/p57↑, 1,   CEA↓, 1,   CLDN1↓, 1,   E-cadherin↑, 8,   F-actin↓, 1,   p‑FAK↓, 1,   GLI3↓, 1,   hnRNPA1↓, 1,   Ki-67↓, 17,   KLF2↓, 1,   MALAT1↓, 1,   MMP1↓, 1,   MMP2↓, 11,   MMP7↓, 1,   MMP9↓, 14,   MMPs↓, 2,   MUC1-C↓, 1,   MUC4↓, 1,   N-cadherin↓, 6,   PAK1↑, 1,   PKA↓, 2,   PKCδ↓, 1,   Rho↓, 1,   serineP↓, 1,   Slug↓, 2,   p‑SMAD2↓, 1,   p‑SMAD3↓, 1,   Snail↓, 3,   TGF-β↓, 3,   TGF-β↑, 1,   TIMP1↑, 2,   TIMP2↑, 4,   TumCI↓, 22,   TumCMig↓, 30,   TumCP↓, 49,   TumCP↑, 1,   TumMeta↓, 19,   Twist↓, 2,   uPA↓, 1,   VCAM-1↓, 1,   Vim↓, 4,   Zeb1↓, 1,   ZO-1↑, 1,   α-SMA↓, 1,   α-SMA↑, 1,   β-catenin/ZEB1↓, 4,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 23,   ATF4↑, 1,   EGFR↓, 3,   Endoglin↓, 1,   eNOS↓, 1,   EPR↓, 1,   EPR↑, 4,   HIF-1↓, 1,   Hif1a↓, 13,   NO↓, 1,   NO↑, 1,   VEGF↓, 16,   VEGF↑, 1,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   CellMemb↑, 1,   GLUT1↓, 3,   GLUT3↓, 1,   GLUT4↓, 1,   P-gp/ABCB1↓, 2,   SLC12A5↓, 1,   SVCT-2↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 15,   COX2/PTGS2↑, 1,   CXCR4↓, 2,   GM-CSF↓, 1,   HMGB1↓, 1,   ICAM-1↓, 1,   IFN-γ↑, 1,   IKKα↓, 1,   IKKα↑, 1,   p‑IKKα↓, 2,   IL1↑, 1,   IL10↓, 1,   IL18↓, 1,   IL1β↓, 7,   IL1β↑, 1,   IL4↓, 1,   IL6↓, 9,   IL8↓, 3,   Imm↑, 3,   Imm↝, 2,   Inflam↓, 4,   IκB↓, 1,   JAK1↓, 1,   JAK2↓, 3,   Macrophages↓, 1,   Neut↓, 1,   NF-kB↓, 28,   NF-kB↑, 1,   NK cell↑, 3,   p65↓, 4,   p‑p65↓, 3,   PD-L1↓, 1,   PD-L1↑, 2,   PGE1↓, 1,   PGE2↓, 1,   PSA↓, 8,   RANTES↓, 1,   SOCS1↑, 1,   T-Cell↑, 1,   TLR4↓, 1,   TNF-α↓, 7,   TNF-α↑, 2,  

Cellular Microenvironment(tgid=17) ⓘ

pH↑, 1,   pH∅, 1,   e-pH↓, 1,   e-pH↑, 1,   i-pH↓, 1,   Temp∅, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

ChE↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 4,   CDK6↓, 1,   CDK6↑, 3,   CYP19↓, 1,   ER(estro)↓, 1,   FKBP5↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 6,   BioAv↑, 5,   BioAv↝, 4,   BioEnh↑, 2,   ChemoSen↑, 25,   Dose?, 1,   Dose↓, 1,   Dose↑, 2,   Dose↝, 46,   Dose∅, 5,   eff↓, 23,   eff↑, 64,   eff↝, 3,   eff∅, 2,   Half-Life↓, 2,   Half-Life↑, 1,   Half-Life↝, 2,   RadioS↑, 3,   RadioS↝, 1,   selectivity↑, 33,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 3,   ALAT↓, 2,   ALAT↑, 1,   Albumin↑, 1,   ALP↑, 1,   AR↓, 4,   ascitic↓, 1,   AST↓, 1,   AST↑, 1,   BG↓, 1,   CA125↓, 1,   CEA↓, 1,   CYFRA21-1↓, 1,   EGFR↓, 3,   EZH2↓, 1,   GutMicro↑, 2,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 1,   IL6↓, 9,   Ki-67↓, 17,   LDH↑, 2,   PD-L1↓, 1,   PD-L1↑, 2,   PSA↓, 8,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 14,   antiNeop↑, 1,   AntiTum↑, 6,   cardioP↑, 3,   chemoP↑, 7,   chemoPv↑, 3,   cognitive↑, 1,   fatigue↓, 1,   hepatoP↑, 3,   neuroP↑, 2,   NP/CIPN↓, 1,   OS↑, 24,   Pin1↓, 2,   QoL↑, 7,   radioP↑, 6,   Remission↑, 3,   Risk↓, 4,   toxicity↓, 13,   toxicity↝, 2,   toxicity∅, 1,   TumVol↓, 204,   TumW↓, 46,   UBE2C↓, 1,   Weight↓, 1,   Weight↑, 6,   Weight∅, 3,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   CD8+↑, 2,  
Total Targets: 527

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,   compII↑, 1,   END↑, 1,   SpO2↑, 1,   Stroke↓, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 7,   Catalase↑, 6,   Fenton↓, 1,   GPx↑, 2,   GPx1↑, 1,   GSH↑, 1,   GSTs↑, 3,   HDL↑, 1,   HO-1↑, 3,   lipid-P↓, 3,   MDA↓, 3,   MPO↓, 2,   NOX4↓, 1,   NRF2↑, 3,   RNS↓, 1,   ROS↓, 12,   ROS∅, 1,   SAM-e↑, 1,   SOD↑, 4,   SOD1↑, 1,   TBARS↓, 1,   VitE↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   ATP↝, 1,   compIII↑, 1,   MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

adiP↑, 1,   ALAT↓, 1,   CREB↑, 1,   FASN↓, 1,   FGF21↑, 1,   glucose↓, 1,   LDL↓, 1,   NAD↝, 1,   NADPH↓, 1,   NH3↓, 1,   SREBP1/SREBF1↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 2,   Apoptosis↓, 2,   Bcl-2↑, 1,   Bcl-xL↑, 1,   Casp12↓, 1,   Casp3↓, 2,   Casp9↓, 1,   GranB/GZMB↓, 1,   p‑JNK↓, 1,   MAPK↓, 1,   p38↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 2,   p‑eIF2α↓, 1,   ER Stress↓, 2,   GRP78/BiP↓, 2,   PERK↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3‑Ⅱ/LC3‑Ⅰ↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

HDAC↓, 1,   IGF-1↓, 1,   mTOR↓, 1,   PI3K↑, 2,   PTEN↑, 1,   STAT3↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   APP↓, 1,   Ca+2↝, 1,   CEA↓, 1,   serineP↓, 1,   TGF-β↑, 1,   Treg lymp↝, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

ATF4↓, 2,   Endoglin↑, 1,   p‑eNOS↑, 1,   Hif1a↑, 1,   NO↓, 1,   VEGF↑, 2,  

Barriers & Transport(tgid=15) ⓘ

IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD25+↑, 1,   CD4+↑, 2,   COX2/PTGS2↓, 3,   FOXP3↑, 1,   HMGB1↓, 1,   IFN-γ↓, 1,   IL10↓, 1,   IL10↑, 2,   IL1β↓, 2,   IL4↓, 1,   IL4↑, 1,   IL6↓, 5,   Imm↑, 1,   Inflam↓, 11,   IκB↓, 1,   JAK2↑, 1,   LPS↓, 1,   M2 MC↑, 1,   MCP1/CCL2↓, 1,   NF-kB↓, 5,   PGE2↓, 2,   TNF-α↓, 6,   VitD↑, 2,  

Cellular Microenvironment(tgid=17) ⓘ

NOX↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

BDNF↑, 2,   PSD95↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 2,   BACE/β-secretase↓, 1,   NLRP3↓, 2,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

testos↑, 1,   TSHR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 6,   BioAv↝, 3,   Dose↓, 1,   Dose↑, 2,   Dose↝, 5,   eff↑, 6,   Half-Life↝, 2,   P450↓, 1,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   BMD↑, 1,   BMPs↑, 1,   Calcium↑, 2,   CEA↓, 1,   creat↓, 1,   GutMicro↑, 3,   hs-CRP↓, 1,   IL6↓, 5,   Mag↑, 2,   Urea↓, 1,   VitD↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   AntiDiabetic↑, 1,   AntiP↑, 1,   antiPs↑, 1,   cardioP↑, 4,   chemoP↑, 1,   chemoPv↑, 1,   ChemoSideEff↓, 1,   cognitive↑, 5,   hepatoP↑, 2,   memory↓, 1,   memory↑, 3,   motorD↓, 1,   neuroP↑, 9,   Obesity↓, 3,   OS↑, 2,   RenoP↑, 1,   Risk↓, 1,   toxicity↓, 9,   toxicity↝, 4,   toxicity∅, 7,   Weight↑, 1,   Weight∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↓, 1,   AntiFungal↑, 1,   AntiViral↑, 1,   Bacteria↓, 3,   Sepsis↓, 1,  
Total Targets: 172

Scientific Paper Hit Count for: TumVol, Tumor Volume
16 Magnetic Fields
9 Silver-NanoParticles
8 doxorubicin
8 Magnetic Field Rotating
7 Curcumin
7 Quercetin
5 Apigenin (mainly Parsley)
5 Boron
5 EGCG (Epigallocatechin Gallate)
5 Hydrogen Gas
4 itraconazole
4 immunotherapy
4 Shikonin
4 Thymoquinone
3 Vitamin C (Ascorbic Acid)
3 Ashwagandha(Withaferin A)
3 Betulinic acid
3 Dichloroacetate
3 Evodiamine
3 Fenbendazole
3 Ginkgetin
3 Inositol
3 Ivermectin
3 metronomic chemo
3 Silymarin (Milk Thistle) silibinin
2 cetuximab
2 Photodynamic Therapy
2 EMF
2 Gold NanoParticles
2 Allicin (mainly Garlic)
2 Baicalein
2 Berberine
2 Beta-Caryophyllene
2 Caffeic acid
2 Radiotherapy/Radiation
2 Centella asiatica / Gotu kola → asiaticoside
2 Chlorogenic acid
2 Chrysin
2 Cisplatin
2 Chemotherapy
2 Eugenol
2 Fisetin
2 Formononetin
2 Gallic acid
2 5-fluorouracil
2 Orlistat
2 Hibiscus sabdariffa
2 Honokiol
2 Hyperoside
2 Juglone
2 SDG/lignans
2 capecitabine
2 Naringin
2 Terpinen-4-ol / Tea Tree Oil
2 Aflavin-3,3′-digallate
1 1,8-Cineole
1 3-bromopyruvate
1 chemodynamic therapy
1 wortmannin
1 Ajoene (compound of Garlic)
1 Alpha-Lipoic-Acid
1 low dose naltrexone
1 Artemisinin
1 Berbamine
1 Brucea javanica
1 Bromelain
1 borneol
1 Vitamin D3
1 Boswellia (frankincense)
1 α-Bisabolol / Chamomile oil
1 Caffeine
1 Zinc
1 Capsaicin
1 Carvacrol
1 Cannabidiol
1 Celastrol
1 chaetocin
1 chitosan
1 Cucurbitacin
1 Oxaliplatin
1 Cynaropicrin
1 Metformin
1 Bortezomib
1 Deguelin
1 diet FMD Fasting Mimicking Diet
1 diet Methionine-Restricted Diet
1 Dandelion Root
1 Ginkgo biloba-EGb 761
1 Docetaxel
1 Emodin
1 Tetrahydroxystilbene glucoside
1 Electrical Pulses
1 Ferulic acid
1 Paclitaxel/Taxol
1 Fucoidan
1 Garcinol
1 Geraniol
1 Ginger/6-Shogaol/Gingerol
1 Ginseng
1 Graviola
1 HydroxyCitric Acid
1 Hyperthermia
1 Indole-3-carbinol
1 iodine
1 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
1 Isovitexin
1 Kaempferol
1 Lasiodin
1 Licochalcone A
1 Licorice
1 Lemongrass Extract/Citral
1 Luteolin
1 Lycopene
1 Melatonin
1 Mistletoe/Viscum album Extracts
1 Helleborus niger extracts – Christmas Rose
1 Bicarbonate(Sodium)
1 Phenylbutyrate
1 Piperine
1 probiotics
1 Pterostilbene
1 enzalutamide
1 Resveratrol
1 Rutin
1 salinomycin
1 α-Santalol/Sandalwood oil
1 Selenium
1 Oxygen, Hyperbaric
1 Sulforaphane (mainly Broccoli)
1 Iron
1 Salvia miltiorrhiza
1 Thymol-Thymus vulgaris
1 Magnesium
1 Vitamin K2
1 Xylitol
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:530  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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