Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
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Drug dosage vs efficacy, and actual dosage number of research papers.


Scientific Papers found: Click to Expand⟱
6461- 1,8-Cin,    1,8-cineole (eucalyptol): A versatile phytochemical with therapeutic applications across multiple diseases
- Review, AD, NA - Review, Var, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *Half-Life↝, *toxicity↓, *PGE2↓, *TNF-α↓, *IL1β↓, *NO↓, *NF-kB↓, *PPARγ↓, COX2/PTGS2↓, *ROS↓, *SOD↑, *Catalase↑, *TAC↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *NADPH↑, *GPx↑, *AntiBio↑, *eff↑, *AntiFungal↑, *AntiViral↑, *TRPA1↑, eff↑, TumCCA↑, ROS↑, MAPK↝, mTOR↝, Apoptosis↑, survivin↓, Akt↓, p38↑, cl‑PARP↑, cl‑Casp3⇅, P53↑, BAX↑, Cyt‑c↑, Casp9↑, Dose↝, *Aβ↓, *tau↓, *GSK‐3β↓, *BACE/β-secretase↓, *cardioP↑, MFN2↑,
6467- 1,8-Cin,    Evaluation of in vitro anticancer activity of 1,8-Cineole-containing n-hexane extract of Callistemon citrinus (Curtis) Skeels plant and its apoptotic potential
- in-vitro, Melanoma, A431 - in-vitro, OS, MG63 - in-vitro, Nor, HaCaT
TumCP↓, selectivity↑, AntiCan↑, TumCD↑, Apoptosis↑, Dose↝, ROS↑,
5277- 3BP,    3-Bromopyruvate inhibits pancreatic tumor growth by stalling glycolysis, and dismantling mitochondria in a syngeneic mouse model
- in-vivo, PC, Panc02
HK2↓, selectivity↑, ATP↓, mtDam↑, Dose↝, TumCG↓, Casp3↑, Glycolysis↓, NADPH↓, ATP↓, ROS↑, DNAdam↑, GSH↓, Bcl-2↓, Casp↑, lactateProd↓,
5274- 3BP,    ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1
- in-vitro, PC, NA
eff↑, TumCG↓, TumMeta↓, toxicity↝, Glycolysis↓, toxicity↓, Dose↝,
5263- 3BP,  CET,    3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis
- in-vitro, CRC, DLD1 - NA, NA, HCT116
eff↑, Ferroptosis↓, TumAuto↑, Apoptosis↑, FOXO3↑, AMPKα↑, p‑Beclin-1/ATG6↑, HK2↓, ATP↓, ROS↑, Dose↝, TumVol↓, TumW↓, xCT/SLC7A11↑, GSH↓, eff↓, MDA↑,
5259- 3BP,    Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP
- in-vivo, HCC, NA
ATP↓, TumCD↑, toxicity↓, eff↑, tumCV↓, Dose↝,
5260- 3BP,    Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer
- in-vivo, PC, NA
TumCG↓, toxicity↓, BioAv↝, GAPDH↓, toxicity↑, Dose↝, ATP↓, eff↑, TumCI↓, MMP9↓, toxicity↓,
5269- 3BP,    The anti-metabolite KAT/3BP has in vitro and in vivo anti-tumor activity in lymphoma models.
- in-vitro, HCC, NA
toxicity↑, eff↝, eff↑, Glycolysis↓, HK2↓, AIF↑, Apoptosis↑, NK cell↑, toxicity↑, toxicity↓, Dose↝, AntiTum↑,
5270- 5-ALA,  PDT,    5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy
- Review, Var, NA
other↝, ROS↑, other↝, mtDam↑, Ca+2↑, ER Stress↑, Apoptosis↑, TumAuto↑, other↝, Dose↝, Imm↑,
5466- AF,    Auranofin Inhibition of Thioredoxin Reductase in a Preclinical Model of Small Cell Lung Cancer
- in-vivo, Lung, NA
TrxR↓, Dose↝, RadioS↑, ChemoSen↑, ROS↑, Diff↑, toxicity↓,
5462- AF,    Repurposing Auranofin for Oncology and Beyond: A Brief Overview of Clinical Trials as Mono- and Combination Therapy
- Review, Var, NA
AntiTum↑, Bacteria↓, TrxR↓, ChemoSen↑, Dose↝, ROS↑, Apoptosis↑, mTOR↓,
5455- AF,    Ridaura
- Study, PSA, NA
Dose↝, Half-Life↝,
5470- AF,    Exploring a Therapeutic Gold Mine: The Antifungal Potential of the Gold-Based Antirheumatic Drug Auranofin
- Review, Var, NA
TrxR↓, other↝, IL6↑, IL8↑, NK cell⇅, COX2/PTGS2↓, NOS2↓, NRF2↑, Prx↑, Half-Life↑, Dose↝, ROS↑, NF-kB↓,
5467- AF,    Auranofin Inhibition of Thioredoxin Reductase Sensitizes Lung Neuroendocrine Tumor Cells (NETs) and Small Cell Lung Cancer (SCLC) Cells to Sorafenib as well as Inhibiting SCLC Xenograft Growth
- in-vitro, Lung, NA
TrxR↓, eff↑, Dose↝, OS↑, eff↑,
5444- AG,    A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine
- Review, Var, NA
*Imm↑, *antiOx↑, *Inflam↓, AntiTum↑, eff↑, chemoP↑, Dose↝, TumCMig↓, TumCP↓, Akt↓, GSK‐3β↓, MMP2↓, MMP9↓, EMT↓, PI3K↓, Akt↓, NF-kB↓, Inflam↓, TGF-β1↓, TNF-α↓, IL6↓, Fas↓, FasL↓, NOTCH1↓, JNK↓, TumCG↓,
5435- AG,    Efficacy of Astragalus Membranaceus (Huang Qi) for Cancer-Related Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Studies
- Review, Var, NA
fatigue↓, QoL↑, Dose↝,
4402- AgNPs,    Enhancement of Triple-Negative Breast Cancer-Specific Induction of Cell Death by Silver Nanoparticles by Combined Treatment with Proteotoxic Stress Response Inhibitors
- in-vitro, BC, BT549 - in-vitro, BC, MDA-MB-231 - in-vitro, Nor, MCF10
TumCD↑, selectivity↑, *toxicity↝, Dose↝, OS↑,
4400- AgNPs,  Rad,    Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells
- in-vitro, BC, MCF7 - in-vitro, Nor, MCF10 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, BT549 - in-vivo, BC, MDA-MB-231
ROS↑, DNAdam↑, selectivity↑, TumCG↓, RadioS↑, Dose↝, selectivity↑, other↝, eff↓, eff↑, γH2AX↑, Dose↓, eff↑,
4439- AgNPs,    Anticancer Potential of Green Synthesized Silver Nanoparticles Using Extract of Nepeta deflersiana against Human Cervical Cancer Cells (HeLA)
- in-vitro, Cerv, HeLa
ROS↑, lipid-P↑, MMP↓, GSH↓, TumCCA↑, Apoptosis↑, Necroptosis↑, TumCD↑, Dose↝,
4560- AgNPs,    Exploiting antidiabetic activity of silver nanoparticles synthesized using Punica granatum leaves and anticancer potential against human liver cancer cells (HepG2)
- in-vitro, Liver, HepG2 - in-vitro, Diabetic, NA
AntiCan↑, Dose↝, *antiOx↑, *AntiDiabetic↑, *Bacteria↓,
305- AgNPs,    Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer
- Case Report, HNSCC, NA
OS↑, Dose↓, BioAv↝, toxicity↓, Remission↑, other↝, other↝, other↝, Dose↝, BioAv↝,
2835- AgNPs,  Gluc,    Carbohydrate functionalization of silver nanoparticles modulates cytotoxicity and cellular uptake
- in-vitro, Liver, HepG2
Dose↝, eff↑, ROS↑, eff↝, eff↑, eff↝, eff↑, eff↝,
7426- AgNPs,  CS,    Silver Nanoparticles Formulation of Flower Head's Polyphenols of Cynara scolymus L.: A Promising Candidate against Prostate (PC-3) Cancer Cell Line through Apoptosis Activation
- in-vitro, Pca, PC3 - in-vitro, Lung, A549
*antiOx↑, tumCV↓, eff↑, Dose↝, P53↑, BAX↑, Casp3↑, Casp8↑, Casp9↑, Bcl-2↓,
257- AL,  Cisplatin,    Allicin Overcomes Hypoxia Mediated Cisplatin Resistance in Lung Cancer Cells through ROS Mediated Cell Death Pathway and by Suppressing Hypoxia Inducible Factors
- in-vitro, NSCLC, A549
ROS↑, HIF-1↓, E-cadherin↑, N-cadherin↓, antiOx↓, Dose↝,
2560- AL,    Effect of garlic on platelet aggregation in humans: a study in healthy subjects and patients with coronary artery disease
- ex-vivo, Nor, NA
*AntiAg↑, BioAv↝, Dose↝,
2666- AL,    Targeting the Interplay of Autophagy and ROS for Cancer Therapy: An Updated Overview on Phytochemicals
- Review, Var, NA
Inflam↓, AntiCan↑, ROS↑, MAPK↑, JNK↑, TumAuto↑, other↑, Dose↝, MALAT1↓, Wnt↓, β-catenin/ZEB1↓,
304- ALA,    alpha-Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2-*-generation
- in-vitro, Colon, HT-29
mt-ROS↑, Apoptosis↑, Casp3↑, DNAdam↑, Bcl-xL↓, Dose↝,
5324- ALC,    The anti-wasting effects of L-carnitine supplementation on cancer: experimental data and clinical studies
- Review, Var, NA
*cachexia↓, *Apoptosis↓, *Inflam↓, QoL↑, Dose↝, Weight↑, OS↝, fatigue↓, eff↝,
5319- ALC,    l-carnitine and cancer cachexia: Clinical and experimental aspects
- Review, Var, NA
fatigue↓, QoL↑, *GSH↑, Dose↝,
5361- almon,    Abstract CT190: A multicenter, open-label, single-arm, phase II study: The third generation EGFR tyrosine kinase inhibitor almonertinib for pretreated EGFR T790M-positive locally advanced or metastatic non-small cell lung cancer (APOLLO)
- Trial, NSCLC, NA
EGFR↓, OS↑, Dose↝,
5360- almon,  BEV,    Case report: Almonertinib in combination with bevacizumab for leptomeningeal metastases from epidermal growth factor receptor-mutation non-small cell lung cancer: Case series
- Case Report, NSCLC, NA
BBB↑, Dose↝, eff↓, OS↑,
7403- Amla,    Aqueous Extract of Emblica officinalis Linn (Indian gooseberry) in Combination with Iodine is More Efficacious than Iodine Alone in Mitigating Mucositis in Head and Neck Cancer Patients Undergoing Curative Radiotherapy: Retrospective Observations
- Trial, HNSCC, NA
Mucositis↓, Dose↝, Dose↝, *Bacteria↓, *AntiFungal↑, *AntiViral↑, *hepatoP↑, *RenoP↑, *neuroP↑, Dose↝,
7402- Amla,    Traditional knowledge to clinical trials: A review on therapeutic actions of Emblica officinalis
- Review, Var, NA
*eff↑, *antiOx↑, *AntiCan↑, *Imm↑, *Inflam↓, *AntiArt↑, *Dose↝, *VitC↑, radioP↑, *cardioP↑, *GastroP↑, *Wound Healing↑, *Diar↓, eff↑, NK cell↑, BAX↑, Bcl-2↓, TumCCA↑, Dose↝,
7393- Amla,    Emblica officinalis extract induces autophagy and inhibits human ovarian cancer cell proliferation, angiogenesis, growth of mouse xenograft tumors
- vitro+vivo, Ovarian, OVCAR-3 - in-vitro, Ovarian, SW626
TumCP↓, Beclin-1/ATG6↑, LC3B-II↑, Hif1a↓, Dose↝, TumAuto↑, angioG↓, COL4A3↓, CXCL6/GCP-2↓, TYMP/ECGF1↓, IL1β↓, PDGFRB↓, ChemoSen↑, Dose↝,
6594- Anamu,    Dibenzyl trisulfide induces caspase-independent death and lysosomal membrane permeabilization of triple-negative breast cancer cells
- in-vitro, BC, HCC1806/CRL-2335 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
TumCP↓, TumCMig↓, Bak↑, GADD45A↑, LTA/TNF-β↑, lysoMP↑, P450↓, cl‑PARP↑, Dose↝,
6887- Ang,    Medicinal properties of Angelica archangelica root extract: Cytotoxicity in breast cancer cells and its protective effects against in vivo tumor development
- in-vivo, BC, 4T1 - in-vitro, BC, MCF7
BAX↑, Bcl-2↓, cl‑Casp3↑, Dose↝, TumCG↓,
2635- Api,  CUR,    Synergistic Effect of Apigenin and Curcumin on Apoptosis, Paraptosis and Autophagy-related Cell Death in HeLa Cells
- in-vitro, Cerv, HeLa
TumCD↑, eff↑, TumAuto↑, ER Stress↑, Paraptosis↑, GRP78/BiP↓, Dose↝,
5382- ART/DHA,    A phase I study of intravenous artesunate in patients with advanced solid tumor malignancies
- Trial, Var, NA
AntiCan↑, Dose↝, Dose↝,
2578- ART/DHA,  RES,    Synergic effects of artemisinin and resveratrol in cancer cells
- in-vitro, Liver, HepG2 - in-vitro, Cerv, HeLa
Dose↝, TumCMig↓, Apoptosis↑, necrosis↑, ROS↑, eff↑,
5410- ASA,    Low-Dose Aspirin and the Prevention of Colorectal Cancer in Inflammatory Bowel Disease: A Nationwide Cohort Study
- Study, CRC, NA
Risk↓, Dose↝, Risk↓,
5404- ASA,    Low-Dose Aspirin and Prevention of Colorectal Cancer: Evidence From a Nationwide Registry-Based Cohort in Norway
- Study, CRC, NA
Risk↓, other↝, Dose↝, Risk↓, other↓, other↝, KRAS↓, other↓, other↓,
5406- ASA,    Adjuvant aspirin therapy and colorectal cancer survival
- Trial, CRC, NA
Dose↝, OS∅,
5407- ASA,    Low-dose aspirin reduces the risk of colorectal cancer recurrence in patients with resected PI3K-altered localised disease, according to the ALASCCA trial.
- Trial, CRC, NA
Dose↝, Risk↓,
5396- Ash,    Withania Somnifera (Ashwagandha) and Withaferin A: Potential in Integrative Oncology
- Review, Var, NA
selectivity↑, ROS↑, Apoptosis↑, ChemoSen↑, RadioS↑, NF-kB↓, ER-α36↓, P53↑, *ROS∅, γH2AX↑, DNAdam↑, MMP↓, XIAP↓, IAP1↓, survivin↓, SOD↓, Dose↝, IL6↓, TNF-α↓, COX2/PTGS2↓, p‑Akt↓, NOTCH1↓, FOXO↑, Casp↑, MMP2↓, CSCs↓, *ROS↓, *SOD2↑, chemoP↑, ChemoSen↑, RadioS↑,
3155- Ash,    Overview of the anticancer activity of withaferin A, an active constituent of the Indian ginseng Withania somnifera
- Review, Var, NA
Half-Life↝, Inflam↓, antiOx↓, angioG↓, ROS↑, BAX↑, Bak↑, E6↓, E7↓, P53↑, Casp3↑, cl‑PARP↑, STAT3↓, eff↑, HSP90↓, TGF-β↓, TNF-α↓, EMT↑, mTOR↓, NOTCH1↓, p‑Akt↓, NF-kB↓, Dose↝,
2001- Ash,    Withania somnifera: from prevention to treatment of cancer
- Review, Var, NA
toxicity↓, TumW↓, Dose?, eff↝, Ki-67↓, survivin↓, XIAP↓, PERK↑, p‑RSK↑, CHOP/DDIT3↑, DR5↑, Dose↝, BG↓, DNMTs↓,
5387- AsP,  PacT,    Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy
- in-vivo, Melanoma, B16-F10
Dose↝, TumCG↓, TumCP↓, BioAv↓, BioAv↑, other↑, Apoptosis↑, Bax:Bcl2↑, EPR↑, toxicity↝,
4819- ASTX,    Astaxanthin Induces Apoptosis in MCF-7 Cells through a p53-Dependent Pathway
- in-vitro, BC, MCF7
antiOx↑, AntiTum↑, TumCD↑, P53↑, P21↑, Apoptosis↑, Dose↝, Casp3↑,
5427- ASTX,    Astaxanthin and Cancer Chemoprevention
- Review, Var, NA
chemoP↑, AntiCan↑, chemoPv↑, Risk↓, lipid-P↓, Pain↓, BioAv↑, Dose↝,
5445- ATV,    Atorvastatin
- NA, Nor, NA
*cardioP↑, *LDL↓, HMG-CoA↓, Half-Life↝, BioAv↓, Dose↝,

Showing Research Papers: 1 to 50 of 514
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 514

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

2/16-OHE1↑, 1,   6IL↑, 1,   8-oxo-dG↓, 1,   8-oxo-dG↑, 1,   ACE/ACE1↓, 1,   ADCY4↑, 1,   AntiBio↓, 1,   AntiBio↑, 1,   APE1/APEX1↓, 1,   APG↓, 2,   CD47↓, 1,   COL4A3↓, 1,   compII↓, 1,   CR↑, 1,   CUL1↝, 1,   CUL5↝, 1,   CX43/GJA1↓, 1,   CXCL6/GCP-2↓, 1,   CYP51/14LDM↓, 1,   DCR↑, 2,   DCR↝, 1,   E2F4↑, 1,   ENL↑, 1,   GSTM1↑, 1,   H3K9↓, 1,   HKMT↓, 1,   HLA-I/II↑, 1,   HSP60/HSPD1↓, 2,   HTRA↓, 1,   IGF-2R↑, 2,   Ingr?, 1,   Ingr↑, 1,   JAG1↑, 1,   K+↑, 1,   LC↑, 2,   LIFR/CD118↓, 1,   mal↓, 1,   miR-106b↓, 2,   miR-124-3p↓, 1,   miR-199↓, 1,   miR-375↑, 1,   miR-542↓, 1,   Mucositis↓, 3,   NA↑, 3,   Nausea↓, 3,   Nausea∅, 2,   NEU1↑, 1,   NLR↓, 1,   OGF↑, 2,   OGFr↑, 3,   ORR↑, 1,   PA↑, 1,   PC↑, 1,   PFS↓, 1,   PFS↑, 4,   PGI2↓, 1,   PSEN1/PS1↓, 1,   RBC↑, 3,   SUV39H↓, 3,   TRADD↑, 1,   TTP↑, 1,   TumNum?, 1,   TYMP/ECGF1↓, 1,   UBE2L3/UBCH7↑, 1,   UFR↑, 1,   Vomit↓, 3,   Vomit∅, 2,   WBC↑, 2,   WDR72↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 7,   antiOx⇅, 1,   ARE↓, 1,   Catalase↓, 5,   Catalase↑, 2,   compI↓, 3,   CoQ10↑, 1,   CYP1A1↓, 1,   CYP1A1↑, 1,   CYP2E1↑, 1,   Fenton↑, 2,   Ferroptosis↓, 1,   Ferroptosis↑, 9,   GPx↓, 2,   GPx↑, 2,   GPx4↓, 4,   GSH↓, 19,   GSH↑, 6,   GSH/GSSG↓, 2,   GSR↑, 1,   GSTA1↑, 1,   GSTs↑, 1,   GSTZ1↓, 1,   GSTZ1↝, 1,   H2O2↓, 1,   H2O2↑, 7,   mt-H2O2↑, 1,   HO-1↓, 6,   HO-1↑, 2,   HO-2↓, 1,   ICD↑, 1,   Iron↑, 2,   i-Iron↓, 1,   lipid-P↓, 2,   lipid-P↑, 5,   MDA↓, 2,   MDA↑, 3,   i-MDA↑, 1,   MFN2↑, 1,   MPO↓, 1,   NAF1↓, 1,   NQO1↑, 1,   NRF2↓, 5,   NRF2↑, 9,   NRF2↝, 1,   OXPHOS↓, 3,   OXPHOS↑, 5,   OXPHOS↝, 1,   mt-OXPHOS↓, 1,   PARK2↑, 1,   Prx↑, 1,   Prx6↑, 1,   ROS↓, 8,   ROS↑, 113,   i-ROS↑, 1,   mt-ROS↑, 9,   SIRT3↑, 1,   SOD↓, 6,   SOD↑, 4,   mt-SOD↑, 1,   SOD2↓, 2,   Thiols↓, 2,   Trx↓, 2,   Trx1↓, 1,   TrxR↓, 7,   TrxR1↓, 1,   TrxR1↑, 1,   uricA↓, 1,   xCT/SLC7A11↓, 3,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   FTH1↓, 1,   IronCh↑, 1,   selm↑, 1,   Tf↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ABL1↓, 1,   AIF↑, 3,   ATP↓, 17,   ATP↑, 3,   CDC2↓, 1,   CDC25↓, 3,   compIII↓, 1,   ETC↓, 5,   ETC↑, 1,   ETC↝, 1,   Insulin↓, 2,   mitResp↓, 1,   MKK4↓, 1,   MKK7↓, 1,   MMP?, 1,   MMP↓, 42,   MMP↑, 1,   MPT↓, 1,   MPT↑, 4,   mtDam↓, 1,   mtDam↑, 17,   OCR↓, 5,   OCR↑, 2,   PGC-1α↑, 4,   PHB↓, 1,   PINK1↑, 1,   c-Raf↓, 1,   SDH↓, 1,   XIAP↓, 14,   XIAP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 2,   ACC↑, 1,   ACLY↓, 1,   ACSL4↑, 2,   AKT1↓, 2,   ALAT↓, 3,   ALAT↑, 1,   AMPK↓, 1,   AMPK↑, 8,   p‑AMPK↑, 1,   ATG7↑, 1,   BUN↓, 3,   cMyc↓, 6,   CREB↓, 1,   CYP3A4↓, 3,   ECAR↝, 1,   FASN↓, 2,   GAPDH↓, 1,   glucoNG↓, 1,   glucose↓, 1,   glucose↝, 1,   GlucoseCon↓, 8,   GLUT2↓, 1,   Glycolysis↓, 18,   HK2↓, 12,   HMG-CoA↓, 3,   IDH1↓, 1,   IR↓, 1,   lactateProd↓, 14,   LDH↑, 2,   LDHA↓, 3,   lipoGen↓, 2,   NADH:NAD↓, 1,   NADPH↓, 1,   NADPH↑, 1,   PCK1↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 5,   PFK↓, 2,   PFK1↓, 1,   PKM2↓, 9,   PPARα↓, 1,   PPARγ↑, 4,   p‑S6K↓, 1,   SCD1↓, 1,   SIRT1↓, 3,   SIRT1↑, 5,   SIRT2↓, 1,   SREBP1/SREBF1↓, 1,   TCA↑, 1,   Warburg↓, 7,  

Cell Death(tgid=5) ⓘ

AhR↑, 1,   Akt↓, 47,   Akt↑, 3,   p‑Akt↓, 18,   APAF1↑, 2,   Apoptosis↓, 2,   Apoptosis↑, 122,   Apoptosis∅, 1,   mt-Apoptosis↑, 3,   ASK1↑, 1,   ATF2↓, 1,   BAD↓, 1,   BAD↑, 1,   Bak↑, 3,   BAX↓, 2,   BAX↑, 39,   Bax:Bcl2↑, 6,   Bcl-2↓, 50,   Bcl-2↑, 1,   Bcl-xL↓, 8,   Bcl-xL↑, 1,   BID↑, 1,   BIM↑, 1,   Casp↑, 18,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp1↑, 2,   Casp12↝, 1,   Casp2↑, 1,   Casp3↓, 1,   Casp3↑, 52,   cl‑Casp3↑, 12,   cl‑Casp3⇅, 1,   Casp7↑, 7,   cl‑Casp7↑, 2,   Casp8↑, 10,   Casp9↓, 1,   Casp9↑, 27,   p‑Casp9↑, 1,   cl‑Casp9↑, 4,   Chk2↓, 1,   Chk2↑, 1,   Cyt‑c↓, 2,   Cyt‑c↑, 32,   Cyt‑c↝, 2,   Diablo↑, 3,   DR4↑, 2,   DR5↑, 5,   FADD↑, 1,   Fas↓, 1,   Fas↑, 11,   FasL↓, 1,   FasL↑, 4,   Ferroptosis↓, 1,   Ferroptosis↑, 9,   GSDMD↑, 3,   cl‑GSDME↑, 1,   hTERT/TERT↓, 2,   IAP1↓, 2,   IAP2/BIRC3↓, 2,   iNOS↓, 3,   JNK↓, 3,   JNK↑, 9,   p‑JNK↓, 1,   p‑JNK↑, 4,   lysoMP↑, 1,   MAPK↓, 9,   MAPK↑, 6,   MAPK↝, 1,   Mcl-1↓, 9,   Mcl-1↑, 1,   MDM2↓, 2,   MOMP↑, 4,   Myc↓, 3,   Myc↑, 1,   Necroptosis↑, 2,   necrosis↑, 3,   NOXA↑, 3,   p27/CDKN1B↓, 2,   p27/CDKN1B↑, 4,   p38↓, 2,   p38↑, 6,   p‑p38↓, 3,   p‑p38↑, 3,   Paraptosis↑, 1,   pS2/TFF1↓, 1,   PUMA↑, 4,   Pyro↑, 5,   p‑RSK↑, 1,   survivin↓, 24,   Telomerase↓, 4,   TRPV1↑, 1,   TumCD↓, 2,   TumCD↑, 23,   TumCD∅, 1,   YAP/TEAD↓, 1,   YAP/TEAD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

AMPKα↑, 2,   EF-1α↓, 1,   HER2/EBBR2↓, 4,   Sp1/3/4↓, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cJun↓, 2,   cJun↑, 1,   EZH2↓, 1,   H3↓, 2,   H3↑, 1,   p‑H3↓, 2,   ac‑H3↓, 1,   ac‑H3↑, 3,   H4↑, 2,   ac‑H4↓, 1,   ac‑H4↑, 2,   HATs↓, 1,   HATs↑, 2,   miR-21↓, 1,   miR-30a-5p↑, 1,   other?, 2,   other↓, 9,   other↑, 13,   other↝, 42,   p‑pRB↓, 1,   SD↑, 3,   tumCV↓, 46,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 4,   cl‑CHOP/DDIT3↑, 1,   p‑eIF2α↓, 1,   ER Stress↓, 1,   ER Stress↑, 13,   GRP78/BiP↓, 3,   GRP78/BiP↑, 1,   HSP27↓, 1,   HSP27↑, 1,   HSP70/HSPA5↓, 2,   HSP70/HSPA5↑, 3,   HSP70/HSPA5⇅, 1,   HSP90↓, 6,   HSP90↑, 1,   IRE1↑, 1,   PERK↑, 1,   UPR↑, 1,   XBP-1↓, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG3↑, 1,   ATG5↑, 3,   Beclin-1/ATG6↑, 6,   Beclin-1/ATG6⇅, 1,   p‑Beclin-1/ATG6↑, 1,   BNIP3↝, 1,   LAMP2↑, 2,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3B-II↑, 1,   LC3I↑, 2,   LC3II↑, 2,   LC3s↑, 1,   MitoP↑, 1,   p62↓, 1,   p62↑, 1,   SESN2↑, 1,   TumAuto↓, 1,   TumAuto↑, 21,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 2,   p‑ATM↑, 1,   ATR↑, 1,   BRCA1↓, 1,   BRCA2↓, 1,   CHK1↓, 1,   CHK1↑, 1,   DNAdam↓, 3,   DNAdam↑, 25,   DNArepair↓, 8,   DNMT3B↓, 2,   DNMTs↓, 4,   GADD45A↑, 1,   NKX3.1↓, 1,   P53↓, 1,   P53↑, 36,   p53 Wildtype↓, 1,   PARP↓, 2,   PARP↑, 1,   cl‑PARP↓, 1,   cl‑PARP↑, 29,   cl‑PARP1↑, 1,   PCNA↓, 9,   SIRT6↑, 2,   TP53↑, 1,   γH2AX↓, 1,   γH2AX↑, 5,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1?, 1,   CDK1↓, 3,   CDK2↓, 9,   CDK2↑, 1,   CDK4↓, 11,   CDK4↑, 1,   cycA1/CCNA1↓, 3,   CycB/CCNB1↓, 5,   cycD1/CCND1↓, 20,   cycE/CCNE↓, 5,   E2Fs↓, 2,   mitA↑, 2,   P21?, 1,   P21↓, 1,   P21↑, 22,   PLK1↓, 3,   RB1↑, 1,   p‑RB1↓, 2,   TumCCA↓, 2,   TumCCA↑, 76,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 2,   CD133↓, 3,   CD24↓, 1,   CD34↓, 1,   CD44↓, 7,   CDK8↓, 1,   cFos↓, 1,   CSCs↓, 14,   CSCsMark↓, 1,   Diff↑, 5,   EMT↓, 15,   EMT↑, 1,   EP2↓, 1,   EpCAM↓, 1,   ERK↓, 12,   ERK↑, 2,   p‑ERK↓, 10,   FGF↓, 1,   FOXO↑, 2,   FOXO1↑, 1,   FOXO3↓, 1,   FOXO3↑, 1,   FOXO3↝, 1,   GH↓, 1,   Gli1↓, 5,   GSK‐3β↓, 2,   GSK‐3β↑, 4,   p‑GSK‐3β↓, 1,   p‑GSK‐3β↑, 1,   HDAC↓, 16,   HDAC1↓, 1,   HDAC2↓, 3,   HDAC8↓, 1,   HH↓, 9,   HH∅, 1,   HMTs↓, 1,   IGF-1↓, 8,   IGF-1R↓, 1,   IGFBP1↑, 1,   IGFBP3↑, 2,   IGFR↓, 2,   Jun↓, 1,   mTOR↓, 25,   mTOR↝, 1,   p‑mTOR↓, 1,   mTORC1↓, 2,   mTORC2↓, 1,   mTORC2↑, 1,   Nanog↓, 2,   Nestin↓, 1,   NOTCH↓, 5,   NOTCH1↓, 6,   NOTCH3↓, 1,   NOTCH3↑, 1,   OCT4↓, 2,   P70S6K↓, 1,   PDGFRA↓, 1,   PDGFRB↓, 1,   PI3K↓, 35,   PI3K↑, 2,   p‑PI3K↓, 2,   PTEN↓, 1,   PTEN↑, 8,   RAS↓, 2,   Shh↓, 1,   Smo↓, 1,   SOX2↓, 3,   Src↓, 2,   STAT↓, 1,   STAT3↓, 26,   p‑STAT3↓, 4,   p‑STAT3↑, 2,   STAT4↑, 1,   STAT5↓, 1,   TCF↓, 1,   TOP1↓, 3,   TOP2↓, 1,   TOP2↑, 1,   TRPM7↓, 2,   TumCG?, 1,   TumCG↓, 84,   TumCG∅, 2,   VGCC↓, 1,   VGCC↑, 1,   VGSC↓, 1,   Wnt↓, 13,   Wnt/(β-catenin)↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AntiAg↑, 1,   AP-1↓, 1,   CA↓, 1,   Ca+2↓, 3,   Ca+2↑, 13,   Ca+2↝, 2,   CD11b↑, 1,   CD31/PECAM-1↓, 2,   CDKN1C/p57↑, 1,   CEA↓, 1,   CLDN1↓, 1,   Cofilin↓, 1,   COL11A1↓, 1,   E-cadherin↓, 1,   E-cadherin↑, 14,   ER-α36↓, 1,   FAK↓, 8,   p‑FAK↓, 1,   fascin↓, 1,   Fibronectin↓, 1,   ITGB1↓, 2,   ITGB6↓, 1,   Ki-67↓, 21,   KRAS↓, 3,   MALAT1↓, 2,   miR-19b↓, 2,   miR-203↑, 1,   miR-22↑, 1,   miR-29b↑, 1,   MMP1↓, 1,   MMP13↓, 1,   MMP2↓, 23,   MMP3↓, 1,   MMP7↓, 1,   MMP9↓, 28,   MMPs↓, 11,   MUC4↓, 1,   N-cadherin↓, 11,   Na+↑, 1,   NCAM↓, 1,   PAK1↓, 1,   PDGF↓, 3,   PKCδ↓, 2,   PKCδ↑, 1,   RECK↑, 1,   Rho↓, 1,   ROCK1↓, 1,   SMAD3↓, 1,   Snail↓, 6,   SOX4↓, 1,   TGF-β↓, 5,   TGF-β↑, 1,   TGF-β1↓, 1,   TIMP1↓, 1,   TIMP1↑, 4,   TIMP2↑, 5,   TIMP3↑, 1,   Treg lymp↓, 1,   TumCA↓, 1,   TumCI↓, 34,   TumCI↑, 1,   TumCMig↓, 35,   TumCP↓, 82,   TumCP↑, 1,   TumCP⇅, 1,   TumMeta↓, 32,   TumMeta↑, 1,   TumPF↓, 1,   Twist↓, 4,   uPA↓, 3,   uPAR↓, 1,   UroPA↓, 1,   VCAM-1↓, 1,   VEGFR1↓, 2,   Vim↓, 7,   Zeb1↓, 4,   ZEB2↓, 1,   ZO-1↓, 1,   β-catenin/ZEB1↓, 10,   β-catenin/ZEB1↑, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 44,   EGFR↓, 14,   EGR1↑, 1,   Endoglin↑, 1,   EPR↑, 6,   EPR↝, 1,   HIF-1↓, 4,   Hif1a↓, 23,   Hif1a↑, 1,   Hif1a↝, 1,   Hypoxia↓, 6,   miR-126↑, 1,   NO↑, 2,   TXA2↑, 1,   VEGF↓, 29,   VEGFR2/KDR/Flk1↓, 5,   VEGFR2/KDR/Flk1↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 6,   CellMemb↑, 4,   GastroP↑, 1,   GLUT1↓, 2,   GLUT4↓, 2,   IBI↑, 1,   Na+↑, 1,   NHE1↓, 2,   P-gp/ABCB1↓, 8,   P-gp/ABCB1↑, 1,   P-gp/ABCB1⇅, 1,   P-gp/ABCB1∅, 1,   sonoP↑, 3,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ANXA1↓, 1,   CB2 / CNR2↑, 1,   CD14↓, 1,   CD25+↓, 1,   CD4+↓, 1,   CD4+↑, 1,   cellSen?, 1,   COX1↓, 1,   COX2/PTGS2↓, 27,   COX2/PTGS2↑, 2,   CRP↓, 1,   CXCc↓, 1,   CXCL1↓, 1,   CXCR4↓, 3,   Dectin1↝, 1,   FoxP3+↓, 1,   GM-CSF↓, 1,   HMGB1↓, 2,   ICAM-1↓, 1,   IFN-γ↓, 1,   IFN-γ↑, 2,   IKKα↓, 2,   IL1↓, 1,   IL1↑, 1,   IL10↓, 2,   IL12↓, 2,   IL12↑, 1,   IL17↓, 1,   IL18↑, 1,   IL1β↓, 10,   IL2↓, 2,   IL2↑, 2,   IL22↓, 2,   IL23↓, 1,   IL4↓, 1,   IL4↑, 1,   IL6↓, 18,   IL6↑, 1,   IL8↓, 3,   IL8↑, 1,   Imm↑, 21,   INF-γ↝, 1,   Inflam↓, 22,   p‑IκB↓, 1,   JAK↓, 1,   JAK1↓, 2,   JAK2↓, 2,   LTA/TNF-β↑, 1,   pol-M1↝, 1,   M2 MC↓, 1,   MCP1/CCL2↓, 3,   Neut↓, 1,   Neut↑, 3,   NF-kB↓, 45,   NF-kB↑, 2,   p‑NF-kB↑, 1,   NK cell↑, 11,   NK cell⇅, 1,   p50↓, 2,   p65↓, 3,   p‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 4,   PD-L1↑, 2,   PDT+↓, 1,   PGE2↓, 9,   PSA↓, 10,   RANTES↓, 1,   T-Cell↑, 1,   TLR4↓, 1,   TNF-α↓, 17,   TNF-α↑, 3,   VitD↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 2,   pH∅, 1,   e-pH↓, 2,   e-pH↑, 3,   i-pH↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 1,   NLRP3↑, 1,   PP2A↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 5,   AR↝, 1,   CDK6↓, 5,   CDK6↑, 2,   DHT↓, 1,   EstroRS/ERS↑, 1,   testos↓, 1,   testos∅, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 22,   BioAv↑, 31,   BioAv↝, 24,   BioEnh↑, 2,   ChemoSen↑, 77,   ChemoSen⇅, 1,   ChemoSen∅, 2,   CYP1A2↓, 1,   CYP1A2↑, 2,   CYP2A3/CYP2A6↓, 1,   Dose?, 1,   Dose↓, 5,   Dose↑, 15,   Dose↝, 574,   Dose∅, 1,   eff↓, 28,   eff↑, 169,   eff↝, 23,   eff∅, 3,   Half-Life↓, 6,   Half-Life↑, 7,   Half-Life↝, 17,   MDR1↓, 2,   MRP1/ABCC1↓, 1,   P450↓, 3,   RadioS?, 1,   RadioS↓, 1,   RadioS↑, 28,   RadioS↝, 1,   selectivity↑, 78,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 5,   AFP↑, 1,   ALAT↓, 3,   ALAT↑, 1,   AR↓, 5,   AR↝, 1,   AST↓, 3,   AST↑, 1,   BG↓, 3,   BloodF↓, 1,   BloodF↑, 5,   BMD↑, 2,   BRCA1↓, 1,   CA125↓, 2,   CEA↓, 1,   CEC↝, 1,   creat↓, 2,   CRP↓, 1,   CTC↓, 1,   CYFRA21-1↓, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 14,   EstroRS/ERS↑, 1,   EZH2↓, 1,   Ferritin↓, 1,   GutMicro↑, 6,   HemoG↑, 1,   HER2/EBBR2↓, 4,   hTERT/TERT↓, 2,   IL6↓, 18,   IL6↑, 1,   Ki-67↓, 21,   KRAS↓, 3,   LDH↑, 2,   Myc↓, 3,   Myc↑, 1,   NOS2↓, 1,   PD-L1↓, 4,   PD-L1↑, 2,   PSA↓, 10,   TP53↑, 1,   Urea↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↓, 1,   AntiCan↑, 33,   AntiDiabetic↑, 1,   antiNeop↑, 7,   antiNeop∅, 1,   AntiTum↑, 19,   AntiTum∅, 1,   cardioP↑, 8,   CardioT↑, 1,   chemoP↑, 29,   chemoPv↑, 11,   ChemoSideEff↓, 3,   cognitive↑, 2,   fatigue↓, 5,   fatigue∅, 1,   hepatoP↑, 11,   neuroP↑, 7,   NP/CIPN↓, 2,   NP/CIPN↑, 3,   OS?, 2,   OS↑, 56,   OS↝, 2,   OS∅, 2,   Pain↓, 6,   QoL↑, 22,   QoL∅, 2,   radioP?, 1,   radioP↑, 11,   Remission↑, 7,   RenoP↓, 1,   RenoP↑, 4,   Risk↓, 33,   Risk↑, 1,   Risk↝, 1,   Risk∅, 1,   stomatitis↓, 1,   toxicity↓, 43,   toxicity↑, 5,   toxicity↝, 22,   toxicity∅, 3,   TumVol?, 1,   TumVol↓, 41,   TumVol⇅, 1,   TumW↓, 15,   TumW⇅, 1,   Weight↑, 8,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   CD8+↑, 6,   Dectin1↝, 1,   Diar↓, 1,   Diar⇅, 1,   Inf↓, 2,   Sepsis↓, 1,  
Total Targets: 851

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 6,   compII↑, 1,   Ingr?, 1,   Ingr↝, 1,   Stroke↓, 3,   TRPA1↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 33,   Catalase↑, 11,   GPx↑, 8,   GPx1↑, 1,   GSH↑, 9,   GSR↑, 2,   GSTA1↓, 1,   GSTA1↑, 2,   GSTs↑, 5,   H2O2↓, 2,   HDL↑, 2,   HO-1↑, 7,   Iron↑, 1,   lipid-P↓, 10,   MDA↓, 5,   MPO↓, 1,   NQO1↑, 1,   Nrf1↑, 1,   NRF2↑, 9,   ROS↓, 35,   ROS⇅, 1,   ROS∅, 3,   selenoP↑, 1,   SOD↑, 13,   SOD1↑, 1,   SOD2↑, 2,   TAC↑, 1,   VitC↑, 2,   VitE↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   compIII↑, 1,   ETC↓, 1,   Insulin↑, 1,   MMP↓, 1,   MMP↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACLY↓, 1,   ALAT↓, 4,   BUN?, 1,   glucose↓, 1,   LDH↓, 1,   LDL↓, 5,   NADPH↓, 1,   NADPH↑, 1,   PPARγ↓, 1,   SIRT1↑, 2,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 1,   Apoptosis↓, 2,   BAX↓, 2,   Bcl-2↓, 1,   Bcl-2↑, 1,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 3,   Casp9↓, 2,   Cyt‑c↓, 1,   GranB/GZMB↓, 1,   iNOS↓, 5,   p‑JNK↓, 2,   MAPK↓, 2,   p38↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

HCAR2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 3,   other?, 1,   other↓, 1,   other↑, 3,   other↝, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   HSP70/HSPA5↑, 2,   HSPs↑, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3‑Ⅱ/LC3‑Ⅰ↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   DNArepair↑, 1,   PCNA↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

GSK‐3β↓, 1,   IGF-1↑, 1,   mTOR↓, 1,   OCT4↓, 1,   PI3K↓, 1,   PI3K↑, 1,   PTEN↑, 2,  

Migration(tgid=13) ⓘ

AntiAg↑, 2,   APP↓, 1,   Ca+2↓, 1,   CLDN1↑, 1,   MMP9↓, 2,   TGF-β↑, 1,   TIMP1↓, 1,   ZO-1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

ATF4↓, 1,   Hif1a↑, 1,   NO↓, 3,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   GastroP↑, 1,   IBI↑, 2,   OATPs↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX1↓, 1,   COX2/PTGS2↓, 5,   CRP↓, 1,   CXCR4↓, 1,   HCAR2↑, 1,   IFN-γ↓, 3,   IL1↓, 1,   IL10↓, 1,   IL10↑, 1,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 7,   IL2↓, 1,   IL4↓, 2,   IL6↓, 9,   IL8↓, 2,   Imm↑, 6,   Inflam↓, 33,   IκB?, 1,   LPS↓, 1,   MyD88↓, 1,   NF-kB↓, 6,   NK cell↑, 1,   PGE2↓, 5,   TLR4↓, 1,   TNF-α↓, 10,   TRIF↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BChE↓, 1,   BDNF↑, 2,   tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 3,   BACE/β-secretase↓, 3,   NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

GR↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 5,   BioAv↑, 15,   BioAv↝, 4,   BioEnh↑, 1,   Dose⇅, 1,   Dose↝, 8,   eff↓, 1,   eff↑, 5,   eff↝, 1,   Half-Life↓, 1,   Half-Life↑, 1,   Half-Life⇅, 1,   Half-Life↝, 5,   P450↓, 2,   P450↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 4,   ALP↓, 2,   AST↓, 4,   BG↓, 1,   BMD↑, 1,   creat↓, 3,   CRP↓, 1,   GutMicro↑, 3,   IL6↓, 9,   LDH↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 4,   antiAll↑, 1,   AntiArt↑, 2,   AntiCan↑, 5,   AntiDiabetic↑, 6,   AntiP↓, 1,   antiPs↑, 1,   cachexia↓, 1,   cardioP?, 1,   cardioP↑, 10,   chemoP↑, 7,   cognitive↑, 3,   hepatoP↑, 11,   memory↑, 1,   motorD↓, 1,   MusCon↓, 1,   neuroP↑, 14,   Obesity↓, 2,   Pain↓, 2,   radioP↑, 1,   RenoP↑, 4,   Risk↓, 2,   Risk↑, 3,   Risk↝, 1,   toxicity↓, 20,   toxicity↑, 1,   toxicity↝, 6,   toxicity∅, 8,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 6,   AntiViral↑, 6,   Bacteria↓, 8,   CD8+↑, 1,   Diar↓, 2,   Sepsis↓, 1,  
Total Targets: 205

Scientific Paper Hit Count for: Dose, Dosage
18 Radiotherapy/Radiation
16 Magnetic Fields
14 Chemotherapy
11 Hydrogen Gas
10 Lycopene
9 Selenium
9 Sulforaphane (mainly Broccoli)
9 Hyperthermia
9 Magnetic Field Rotating
8 Curcumin
8 Resveratrol
8 itraconazole
7 Silver-NanoParticles
7 Formononetin
7 Ginger/6-Shogaol/Gingerol
7 Ginkgetin
7 Inositol
6 3-bromopyruvate
6 Cisplatin
6 Carvacrol
6 immunotherapy
6 iodine
6 Silymarin (Milk Thistle) silibinin
6 Kaempferol
6 Licorice
6 Lactoferrin/Talactoferrin
6 SDG/lignans
5 Auranofin
5 Paclitaxel/Taxol
5 α-Bisabolol / Chamomile oil
5 Dandelion Root
5 Lemongrass Extract/Citral
5 Gossypol/AT-101
5 Vitamin C (Ascorbic Acid)
5 Hibiscus sabdariffa
5 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
5 isoflavones
5 Ivermectin
5 Luteolin
5 Marjoram (Origanum majorana)
5 Phenethyl isothiocyanate
5 Selenium NanoParticles
4 cetuximab
4 Aspirin
4 Butyrate
4 chitosan
4 doxorubicin
4 Dichloroacetate
4 Echinacea
4 Ginkgo biloba-EGb 761
4 Electrical Pulses
4 Exercise
4 Fisetin
4 Genistein (soy isoflavone)
4 Honokiol
4 Indole-3-carbinol
4 Inulin Prebiotic
4 capecitabine
4 probiotics
4 Bicarbonate(Sodium)
4 Phenylbutyrate
4 EMF
4 SonoDynamic Therapy UltraSound
4 Thymoquinone
3 Cynara scolymus/Globe Artichoke/Artichoke Extract
3 Allicin (mainly Garlic)
3 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
3 Ashwagandha(Withaferin A)
3 Baicalein
3 Beta-Caryophyllene
3 Bromelain
3 Capsaicin
3 Cat’s Claw
3 Celastrol
3 chaetocin
3 Chrysin
3 Metformin
3 Diclofenac
3 Docosahexaenoic Acid
3 diet FMD Fasting Mimicking Diet
3 Disulfiram
3 Ellagic acid
3 Eurycomanone
3 Eugenol
3 Fenbendazole
3 Flaxseed/Linseed
3 Fucoidan
3 Shilajit/Fulvic Acid
3 Ginkgo biloba
3 Vitamin D3
3 Grapeseed extract
3 HydroxyTyrosol
3 Lapatinib
3 low dose naltrexone
3 Rosmarinic acid
3 Selenite (Sodium)
2 1,8-Cineole
2 Photodynamic Therapy
2 Astragalus
2 Acetyl-l-carnitine
2 almonertinib
2 Bevacizumab (brand Avastin)
2 Artemisinin
2 Ascorbyl Palmitate
2 Astaxanthin
2 Aloe anthraquinones
2 beta-glucans
2 Betulinic acid
2 Bicalutamide
2 Boron
2 Sorafenib (brand name Nexavar)
2 Chlorogenic acid
2 Hydroxycinnamic-acid
2 Coenzyme Q10
2 Crocetin
2 Cynaropicrin
2 Dasatinib/Phyrago
2 diet Plant based
2 Docetaxel
2 Copper and Cu NanoParticles
2 eicosapentaenoic acid
2 5-fluorouracil
2 Evodiamine
2 Ferulic acid
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Geraniol
2 Gold NanoParticles
2 Oxygen, Hyperbaric
2 Isobavachalcone
2 Isoliquiritigenin
2 isoorientin
2 Recombinant Methioninase
2 Vitexin
2 Juglone
2 Lactobacillus
2 Licochalcone A
2 Linalool
2 nivolumab
2 metronomic chemo
2 Niclosamide (Niclocide)
2 Terpinen-4-ol / Tea Tree Oil
2 Piperlongumine
2 Bifidobacterium
2 Shikonin
2 Aflavin-3,3′-digallate
2 Turmerones
1 5-Aminolevulinic acid
1 Glucose
1 Alpha-Lipoic-Acid
1 DTS(dibenzyl trisulphide) from Anamu
1 Angelica archangelica / Garden Angelica
1 Apigenin (mainly Parsley)
1 Atorvastatin
1 Berberine
1 Biochanin A
1 bempedoic acid
1 Bufalin/Huachansu
1 Brucea javanica
1 Bruteridin(bergamot juice)
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Cannabidiol
1 Celecoxib
1 Centella asiatica / Gotu kola → asiaticoside
1 Quercetin
1 Rutin
1 Chyawanprash
1 Cinnamon
1 Citric Acid
1 Carica papaya leaf extract
1 CUSP9
1 diet Short Term Fasting
1 Zinc
1 Cichoric acid / Chicoric acid
1 EGCG (Epigallocatechin Gallate)
1 Emodin
1 Folic Acid, Vit B9
1 Fennel Oil/Foeniculum vulgare
1 ferumoxytol
1 Bortezomib
1 Arsenic trioxide
1 Vitamin A, Retinoic Acid
1 Gallic acid
1 Gambogic Acid
1 Germanium inorganic
1 Ginkgolide B
1 Glabrescione B
1 carboplatin
1 Graviola
1 HydroxyCitric Acid
1 High-Ozonide Oil
1 Extracorporeal Shock Wave Therapy
1 Gemcitabine (Gemzar)
1 isoquercitrin
1 Isovitexin
1 lambertianic acid
1 Lapachol
1 Lasiodin
1 Lutein
1 Magnesium
1 Mistletoe/Viscum album Extracts
1 Helleborus niger extracts – Christmas Rose
1 nicotinamide adenine dinucleotide
1 ipilimumab
1 Aidi injection
1 Propolis -bee glue
1 Polyphenols
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 Rauwolfia serpentina/Indian Snakeroot
1 salinomycin
1 α-Santalol/Sandalwood oil
1 Sulfasalazine
1 irinotecan
1 Triphala
1 Transarterial Chemoembolization
1 Whole Body Vibration
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:1114  State#:%  Dir#:4
wNotes=0 sortOrder:rid,rpid

 

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