antiOx Cancer Research Results

antiOx, anti-oxidant activities: Click to Expand ⟱
Source:
Type:
Various antioxidants such as Nrf2, SODs, catalase, GPxs, PRDXs, and GSTs are altered in different cancers and have been linked to prognosis. Their overexpression can correlate with aggressive tumor behavior and resistance to treatment in many contexts.
Scientific Papers found: Click to Expand⟱
3972- ACNs,    Recent Research on the Health Benefits of Blueberries and Their Anthocyanins
- Review, AD, NA - Review, Park, NA
*cardioP↑, *neuroP↑, *Inflam↓, *antiOx↓, *GutMicro↑, *Half-Life↑, *LDL↓, *adiP↓, *HDL↑, *CRP↓, *IL1β↓, *Risk↓, *Risk↓, *cognitive↑, *memory↑, *other↑, *BOLD↑, *NO↓, *MDA↓, *GSH↑, *VitC↑, *SOD↑, *GPx↑, *eff↓, *eff↓, *eff↓, *eff↝, *Risk↓,
7396- Amla,    Enhancing cognitive memory function using Phyllanthus emblica polysaccharides via modulating autophagy and reshaping the gut microbiota
- in-vivo, AD, NA
*Inflam↓, *antiOx↓, *GutMicro↑, *cognitive↑, *TNF-α↓, *IL6↓, *IL1β↓, *MDA↓, *IL4↑, *IL10↑, *TAC↑, *ATG5↑, *Beclin-1/ATG6↑, *LC3B↑, *LRP1↑, *BACE/β-secretase↓, *APP↓, *Aβ↓, *tau↓,
6598- Anamu,    Amazonian Plants: A Global Bibliometric Approach to Petiveria alliacea L. Pharmacological and Toxicological Properties
- Review, Var, NA
*AChE↓, *antiOx↓, ATP↓, *toxicity↓,
6400- ANE,  FEO,    A comprehensive review of the neurological effects of anethole
- Review, AD, NA
*neuroP↑, *antiOx↓, *ROS↓, *Inflam↓, *TNF-α↓, *IL1β↓, *IL6↓, *motorD↑, *MAOA↓, *memory↑, *AChE↓, *PI3K↑, *Akt↑, *mTOR↑,
2483- Ba,    Baicalein and 12/15-Lipoxygenase in the Ischemic Brain
- in-vivo, Stroke, NA
*12LOX↓, *antiOx↓, *neuroP↑,
3684- BBR,    Neuroprotective effects of berberine in animal models of Alzheimer’s disease: a systematic review of pre-clinical studies
- Review, AD, NA
*Inflam↓, *antiOx↓, *AChE↓, *BChE↓, *MAOA↓, *MAOB↓, *lipid-P↓, *GSH↑, *ROS↓, *APP↓, *BACE/β-secretase↓, *p‑tau↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *MAPK↓, *PI3K↓, *Akt↓, *neuroP↑, *memory↑,
4619- Bor,    Using Boron Supplementation in Cancer Prevention and Treatment: A Review Article
- Review, Var, NA
Dose↝, Risk↓, *antiOx↓, *Inflam↓, ChemoSen↑, AntiCan↑, *PCNA↓, *ROS↓, other↝,
6550- BSB,    α-bisabolol β-D-fucopyranoside as a potential modulator of β-amyloid peptide induced neurotoxicity: An in vitro &in silico study
- in-vivo, AD, NA
*AChE↓, *antiOx↓, *neuroP↑,
5932- CAR,    Carvacrol attenuates mucosal barrier impairment and tumorigenesis by regulating gut microbiome
- in-vivo, IBD, NA - in-vivo, Park, NA
*GutMicro↑, Risk↓, *Inflam↓, *antiOx↓, *ZO-1↑, *iNOS↓, *IL6↓, *NO↓, *PGE2↓, *memory↑, *TLR4↓, *NF-kB↓, *IBI↑, *CLDN3↑, *CLDN1↑, *MUC1↑, *OCLN↑, *iNOS↑, *COX2/PTGS2↓, *IFN-γ↓, IL1β↓, ADAM10?,
6014- CGA,    Exploring the Pharmacological Potential of Chlorogenic acid as an Anti-Cancer Agent and a Call for Advance Research
- Review, Var, NA
AntiCan↑, *hepatoP↑, *Bacteria↓, *antiOx↓, *AntiDiabetic↑, Apoptosis↓, TumCG↓, angioG↓, TumCI↓, TumCMig↓, ROS↝, Inflam↝,
6041- CGA,    Effect of Chlorogenic Acid Intake on Cognitive Function in the Elderly: A Pilot Study
- Trial, AD, NA
*Dose↝, *memory↑, *Risk↓, *cognitive↑, *Aβ↓, *antiOx↓, *motorD↑,
6000- Chit,    Chitosan in Modern Pharmacotherapy: From Drug Encapsulation to Targeted Delivery Systems
- Review, Var, NA
DDS↑, toxicity↓, TJ↓, BioAv↑, *Bacteria↓, *Inflam↓, *antiOx↓, Wound Healing↑, other↝, eff↑, eff↑,
6214- CUR,    Curcumin Nanoparticles-related Non-invasive Tumor Therapy, and Cardiotoxicity Relieve
- Review, CardioV, NA
TumCD↓, TumCI↓, *Inflam↓, *antiOx↓, *AntiTum↓, NF-kB↓, COX2/PTGS2↓, Casp9↓, ROS↑, BioAv↑, RadioS↑, ChemoSen↑, Imm↑, PhotoS↑, sonoS↑, 5LO↓, iNOS↓, IL2↓, TNF-α↓, Casp9↑, Casp3↑, Bcl-2↓, BAX↑, Apoptosis↑, ER Stress↑, cycD1/CCND1↓, CDK2↓, CycB/CCNB1↓, TumCCA↑, MMPs↓, *radioP↑, chemoP↑, hepatoP↑, cardioP↑, Synergy↑, PhotoS↑, eff↑, ROS↑, GSH↓,
6730- Dipy,  ASA,    Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner
- vitro+vivo, CRC, NA
*AntiThr↑, Synergy↑, ER Stress↑, UPR↑, *AntiAg↑, *COX1↓, Risk↓, TumCG↓, Apoptosis↑, HMG-CoA↓, *Inflam↓, *antiOx↓,
6366- DRE,    A comprehensive review of the benefits of Taraxacum officinale on human health
- Review, Var, NA
*diuretic↑, *hepatoP↑, *Imm↑, *Bacteria↓, *AntiArt↑, *AntiDiabetic↑, *Obesity↓, *antiOx↓, *AntiCan↑, Dose?,
6574- EU,    Effects of Eurycoma longifolia Jack on chronic cerebral hypoperfusion-induced oxidative damage and memory deficit in rats
- in-vivo, Nor, NA
*cognitive↑, *antiOx↓, *MDA↓, *CRP↓, *neuroP↑, *Inflam↓,
6376- Eug,    Preparation, characterization, oral bioavailability, and pharmacodynamic study of eugenol-porous silica solidified powder
- in-vitro, Nor, NA
*Inflam↓, *antiOx↓, *Dose↝, *eff↑,
2825- FIS,    Exploring the molecular targets of dietary flavonoid fisetin in cancer
- Review, Var, NA
*Inflam↓, *antiOx↓, *ERK↑, *p‑cMyc↑, *NRF2↑, *GSH↑, *HO-1↑, mTOR↓, PI3K↓, Akt↓, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, CDK6↓, P21↑, p27/CDKN1B↑, JNK↑, MMP2↓, MMP9↓, uPA↓, NF-kB↓, cFos↓, cJun↓, E-cadherin↑, Vim↓, N-cadherin↓, EMT↓, MMP↓, Cyt‑c↑, Diablo↑, Casp↑, cl‑PARP↑, P53↑, COX2/PTGS2↓, PGE2↓, HSP70/HSPA5↓, HSP27↓, DNAdam↑, Casp3↑, Casp9↑, ROS↑, AMPK↑, NO↑, Ca+2↑, mTORC1↓, p70S6↓, ROS↓, ER Stress↑, IRE1↑, ATF4↑, GRP78/BiP↑, Synergy↑, Synergy↑, Synergy↑, RadioS↑, ChemoSen↑, Half-Life↝,
7018- Fuc,    Absorption Study of Mozuku Fucoidan in Japanese Volunteers
- Trial, Nor, NA
*Dose↝, *BioAv↝, *eff↝, *Inflam↓, *AntiThr↑, angioG↓, *AntiViral↑, *AntiTum↑, *antiOx↓, *BioAv↝,
6567- Ger,    Geraniin inhibits proliferation and induces apoptosis through inhibition of phosphatidylinositol 3-kinase/Akt pathway in human colorectal cancer in vitro and in vivo
- vitro+vivo, CRC, SW480 - in-vitro, CRC, HT29
AntiTum↑, *Inflam↓, *antiOx↓, TumCP↓, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, TumCMig↓, TumCI↓, MMP2↓, MMP9↓, p‑PI3K↓, p‑Akt↓, Dose↝, TumCG↓,
6571- Ger,    Unlocking the therapeutic potential of Geraniol: an alternative perspective for metabolic disease management
- Review, Obesity, NA
*lipidLev↓, *antiOx↓, Inflam↓, *ROS↓, *BioAv↑, *AntiDiabetic↑, *Obesity↓,
7251- Gink,    Ginkgetin: A Promising Multitarget Agent for Diverse Diseases
- Review, Var, NA
*Inflam↓, *antiOx↓, AntiCan↑, *neuroP↑, *cardioP↑, *Bacteria↓, *ROS↓, *lipid-P↓, *NRF2↓, *Keap1↓, *NF-kB↓, *MAPK↓, MMP2↓, M2 MC↓, JAK2↓, STAT3↓, TumCP↓, Casp↑, ChemoSen↑, *BMD↑, *Aβ↓, *Stroke↓, *BioAv↓,
7487- H2,    A comprehensive review of molecular hydrogen as a novel nutrition therapy in relieving oxidative stress and diseases: Mechanisms and perspectives
- Review, Nor, NA
*Inflam↓, *antiOx↓, *Stress↓, *Dose↝, *cardioP↑, *GastroP↑, *BBB↑, *eff↑, *toxicity↓, *Dose↝, *hepatoP↑, *ROS↓, *SOD↑, *TBARS↓, *HDL↑, *LDL↓, *Obesity↓, *GSH↑, *TNF-α↓, *GutMicro↑, *DNAdam↓, *γH2AX↓, *p‑p38↓, *NF-kB↓, *antiAll↑,
6869- HCAs,  FA,  CA,  RosA,    Exploring the potential of cinnamic acid analogues in alzheimer's disease
- Review, AD, NA
*neuroP↑, *antiOx↓, *Inflam↓, *tau↓, *BioAv↓, *BBB↓, *BioAv↑,
7385- IBC,    Fighting cancer by triggering non-canonical mitochondrial permeability transition-driven necrosis through reactive oxygen species induction
- vitro+vivo, Lung, A549 - in-vitro, BC, 4T1
Apoptosis↑, necrosis↑, ROS↑, mtDam↑, Ca+2↑, MPT↑, MMP↓, AntiCan↑, *AntiBio↑, *Inflam↓, *antiOx↓, *neuroP↑, p‑Akt↓, DHODH↓, Diff↑, MAPK↑,
7763- ISL,    Harnessing Liquiritigenin: A Flavonoid-Based Approach for the Prevention and Treatment of Cancer
- Review, Var, NA
AntiCan↑, *antiOx↓, *Inflam↓, TumCP↓, Apoptosis↑, NF-kB↓, PI3K↓, Akt↓, mTOR↓, *AntiArt↑, Casp8↑, Cyt‑c↑, Casp↑, cl‑PARP↑, GutMicro↑, BioAv↑, BioAv↓, Half-Life↓,
9252- ISO, IH,    Isorhamnetin: Reviewing Recent Developments in Anticancer Mechanisms and Nanoformulation-Driven Delivery
- Review, Var, NA
TumCP↓, Apoptosis↑, Casp↑, mtDam↑, MMPs↓, VEGF↓, EMT↓, *antiOx↓, *Inflam↓, *ROS↓, MDR1↓, PI3K↓, Akt↓, MAPK↓, NF-kB↓, Ingr↝, TumCCA↑, CycB/CCNB1↓, CDK1↓, P21↑, ROS↑, AMPK↑, *Ferroptosis↓, *NRF2↑, *HO-1↑, *IronCh↑, *lipid-P↓, *GSH↑, *ACSL4↓, *COX2/PTGS2↓, VEGF↓, angioG↓, E-cadherin↑, N-cadherin↓, uPA↓, *NK cell↑, radioP↑, Imm↑, Neut↑, Eos↑,
7848- ISQ,    Review of anticancer mechanisms of isoquercitin
- Review, Var, NA
BioAv↑, eff↑, *antiOx↓, TumCP↓, *Inflam↓, *AntiDiabetic↑, lipid-P↓, *toxicity↓, *Half-Life↝, *Half-Life↑, *XO↝, *IronCh↝, *VitC↑, *ROS↓, β-catenin/ZEB1↓, Casp3↑, Casp8↑, Casp9↑, MMP↓, p‑ERK↓, p‑cJun↑,
8081- KAE,    The Anticancer Effects and Therapeutic Potential of Kaempferol in Triple-Negative Breast Cancer
- Review, BC, NA
*antiOx↓, *Inflam↓, *neuroP↓, *AntiCan↑, DNAdam↓, Casp3↑, Casp9↑, p‑AMT/GCST/T-protein↑, ROS↑, NRF2↑, Apoptosis↑, cl‑PARP↓, BAX↑, Bcl-2↓, TumCCA↓, angioG↓, MMP3↓, MMP9↓, ChemoSen↑, BioAv↓, Glycolysis↓, cl‑PARP↑, Ca+2↑, MMP↓, ER Stress↑, GRP78/BiP↑, CHOP/DDIT3↑, ATF6↑, angioG↓, VEGF↓, Hif1a↓, chemoP↑, *ROS↓, NRF2↑, BioAv↑,
1778- MLT,    Melatonin: a well-documented antioxidant with conditional pro-oxidant actions
- Review, Var, NA - Review, AD, NA
*ROS↓, *antiOx↓, ROS↑, selectivity↑, Dose↑, *mitResp↑, *ATP↑, *ROS↓, eff↑, ROS↑, Dose↑, *toxicity∅, ROS↑, eff↓, ROS↝, Dose↑, other↑,
1798- NarG,    Naringenin: A potential flavonoid phytochemical for cancer therapy
- Review, Var, NA
*Inflam↓, *antiOx↓, neuroP↑, hepatoP↑, AntiCan↑, Apoptosis↑, TumCCA↑, angioG↓, ROS↝, SOD↑, TGF-β↓, Treg lymp↓, IL1β↓, *BioAv↝, ChemoSen↑, cardioP↑,
4646- OLEC,    Oleocanthal as a Multifunctional Anti-Cancer Agent: Mechanistic Insights, Advanced Delivery Strategies, and Synergies for Precision Oncology
- Review, Var, NA
BioAv↓, *Inflam↓, *antiOx↓, cMET↓, STAT3↓, TNF-α↓, COX2/PTGS2↓, EMT↓, angioG↓, *GutMicro↝, eff↑,
9029- Phyco,    Advances about the study of phycocyanin in the treatment of breast cancer: A review
- Review, BC, NA
*antiOx↓, *Inflam↓, AntiTum↑, Apoptosis↑, ROS↑, mtDam?, TumCCA↑, TumCP↓, Tumccf↓, *toxicity↓, TumCG↓, EMT↓, COX2/PTGS2↓,
5209- PI,    Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP-9 signaling pathway in DU145 cells
- in-vitro, Pca, DU145
TumCP↓, TumCMig↓, Apoptosis↑, p‑Akt↓, MMP9↓, p‑mTOR↓, TumMeta↓, *antiOx↓, *Inflam↓, *hepatoP↑, *Imm↑, *AntiCan↑,
5213- PI,    Induction of apoptosis by piperine in human cervical adenocarcinoma via ROS mediated mitochondrial pathway and caspase-3 activation
- in-vitro, Cerv, HeLa
Apoptosis↑, TumCG↓, ROS↑, MMP↓, DNAdam↑, Casp3↑, TumCCA↑, *Inflam↓, *antiOx↓, *hepatoP↑, ChemoSen↑, CSCs↓,
3924- PTS,    Effect of resveratrol and pterostilbene on aging and longevity
- Review, AD, NA - Review, Stroke, NA
*antiOx↓, *ROS↑, *SOD↑, *GSH↑, *NRF2↑, *MDA↓, *HNE↓, *Inflam↓, *MAPK↓, *IL6↓, *TNF-α↓, *HO-1↑, *cardioP↑, *neuroP↑, *CRM↑, *NLRP3↓,
3361- QC,    Quercetin ameliorates testosterone secretion disorder by inhibiting endoplasmic reticulum stress through the miR-1306-5p/HSD17B7 axis in diabetic rats
- in-vivo, Nor, NA - in-vitro, NA, NA
*BG↓, *ROS↓, *SOD↑, *MDA↓, *ER Stress↓, *iNOS↓, *CHOP/DDIT3↓, *GRP78/BiP↓, *antiOx↓, *Inflam↓, *JAK2↑, *STAT3?,
2431- QC,    The Protective Effect of Quercetin against the Cytotoxicity Induced by Fumonisin B1 in Sertoli Cells
- in-vitro, Nor, TM4
*Apoptosis↓, *ROS↓, *antiOx↓, *MMP↑, *GPI↑, *HK2↑, *ALDOA↑, *PKM1↑, *LDHA↑, *PFKL↑,
2564- RES,    Effect of resveratrol on platelet aggregation by fibrinogen protection
- in-vitro, Nor, NA
*AntiAg↑, *antiOx↓, *COX2/PTGS2↓,
9279- SES, SSM,    Sesamin exhibits potential food-drug interactions through the inhibition of cytochrome P450s and human UDP-glucuronosyltransferases in vitro
- Review, Var, NA
*Inflam↓, *antiOx↓, *hepatoP↓, *TC↓, *CYP2C9↓, *CYP2C19↓, *other↝,
3330- SIL,    Mechanistic Insights into the Pharmacological Significance of Silymarin
- Review, Var, NA
*neuroP↑, *hepatoP↑, *cardioP↑, *antiOx↓, *NLRP3↓, *NAD↑, ROS↓, NLRP3↓, TumCMig↓, *COX2/PTGS2↓, *iNOS↓, *MPO↓, *AChE↓, *LDH↓, *Telomerase↓, *Fas↓,
3653- SIL,    Silibinin ameliorates Aβ25-35-induced memory deficits in rats by modulating autophagy and attenuating neuroinflammation as well as oxidative stress
- in-vivo, AD, NA
*hepatoP↑, *neuroP↑, *cognitive↑, *memory↑, *Inflam↓, *GSH↑, *MDA↓, *Inflam↓, *antiOx↓,
4742- SSE,    Antitumor Effects of Selenium
- Review, Var, NA - Review, Arthritis, NA - Review, Sepsis, NA
*antiOx↓, *Inflam↓, Risk↓, TumCI↓, TumMeta↓, radioP↑, chemoP↑, Apoptosis↑, ROS↑, DNAdam↑, Dose↑, selectivity↑, *other↓, *BioAv↑, ROS↑, MMP↓, Casp↑, *Imm↑, *Pain↓, Sepsis↓, MMP2↓, MMP9↓, *Half-Life↓,
6433- T4O,  CET,    Terpinen-4-ol: A Novel and Promising Therapeutic Agent for Human Gastrointestinal Cancers
- in-vitro, Colon, HT29 - in-vitro, CRC, HCT116 - in-vitro, PC, COLO357 - Human, Colon, NA
TumCG↓, Synergy↑, ChemoSen↑, Apoptosis↑, TumVol↓, TumW↓, *Inflam↓, *antiOx↓, BioAv↝,
1937- TQ,    Migration and Proliferation Effects of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) and Thymoquinone (TQ) on In Vitro Wound Healing Models
- in-vitro, Wounds, 3T3
*ROS↓, *antiOx↓, *BioAv↓, *BioAv↑, *NO↑, *SOD↑, *GPx↑, *Catalase↑,
3554- TQ,    Neuroprotective efficacy of thymoquinone against amyloid beta-induced neurotoxicity in human induced pluripotent stem cell-derived cholinergic neurons
- in-vitro, AD, NA
*GSH↑, *ROS↓, *neuroP↑, *Casp3↓, *Casp7↓, *antiOx↓, *H2O2↓,
4876- Uro,    Urolithin A in Health and Diseases: Prospects for Parkinson’s Disease Management
- Review, Park, NA - Review, AD, NA
*Inflam↓, *antiOx↓, *neuroP↑, *p‑tau↓, *Aβ↓, *Synergy↑, *BioAv↓, *BioAv↑, *GSH↑, *SOD↑, *lipid-P↓, *Catalase↑, *GSR↑, *GPx↑, *ROS↓, *NRF2↑, *GutMicro↑, *Risk↓, *BBB↓, *NLRP3↓, *MAOA↓,
4833- Uro,    Unveiling the potential of Urolithin A in Cancer Therapy: Mechanistic Insights to Future Perspectives of Nanomedicine
- Review, Var, NA - Review, AD, NA - Review, IBD, NA
BioAv↝, TumAuto↝, TumCG↓, TumMeta↓, ChemoSen↑, Imm↑, RadioS↑, BioAv↑, other↝, eff↓, *antiOx↓, *Inflam↓, AntiCan↓, AntiAge↑, chemoP↑, *neuroP↑, *ROS↓, *cognitive↑, *lipid-P↓, *cardioP↑, *TNF-α↓, *IL6↓, GutMicro↑, TumCCA↑, Apoptosis↑, angioG↓, NF-kB↓, PI3K↓, Akt↓, Casp↑, survivin↓, TumCP↓, cycD1/CCND1↓, cMyc↑, BAX↑, Bcl-2↓, COX2/PTGS2↓, P53↑, p38↑, *ROS↓, *SOD↑, *GPx↑, SIRT1↑, FOXO1↑, eff↑, ChemoSen↑,

Showing Research Papers: 1 to 48 of 48

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 48

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GSH↓, 1,   lipid-P↓, 1,   NRF2↑, 2,   ROS↓, 2,   ROS↑, 13,   ROS↝, 3,   SOD↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

mtDam?, 1,   mtDam↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 1,   AMPK↑, 2,   p‑AMT/GCST/T-protein↑, 1,   ATP↓, 1,   DHODH↓, 1,   Glycolysis↓, 1,   HMG-CoA↓, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   Apoptosis↑, 13,   BAX↑, 4,   Bcl-2↓, 4,   Casp↑, 6,   Casp3↑, 6,   Casp8↑, 2,   Casp9↓, 1,   Casp9↑, 5,   Cyt‑c↑, 2,   Diablo↑, 1,   iNOS↓, 1,   necrosis↑, 1,   p38↑, 1,   survivin↓, 1,   TumCD↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 4,   p‑Akt↓, 3,   cMET↓, 1,   p‑ERK↓, 1,   JAK2↓, 1,   JNK↑, 1,   MAPK↓, 1,   MAPK↑, 1,   mTOR↓, 2,   p‑mTOR↓, 1,   p70S6↓, 1,   PI3K↓, 4,   p‑PI3K↓, 1,   STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   cJun↓, 1,   p‑cJun↑, 1,   cMyc↑, 1,   FOXO1↑, 1,   other↑, 1,   other↝, 3,   PhotoS↑, 2,   sonoS↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↑, 1,   ER Stress↑, 4,   GRP78/BiP↑, 2,   HSP27↓, 1,   HSP70/HSPA5↓, 1,   IRE1↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   DNAdam↑, 3,   P53↑, 2,   cl‑PARP↓, 1,   cl‑PARP↑, 3,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK2↓, 2,   CDK4↓, 1,   CDK6↓, 1,   CycB/CCNB1↓, 2,   cycD1/CCND1↓, 3,   cycE/CCNE↓, 1,   P21↑, 2,   p27/CDKN1B↑, 1,   TumCCA↓, 1,   TumCCA↑, 7,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

cFos↓, 1,   CSCs↓, 1,   Diff↑, 1,   mTORC1↓, 1,   TumCG↓, 7,   TumCP↓, 8,  

Migration(tgid=13) ⓘ

Ca+2↑, 3,   E-cadherin↑, 2,   EMT↓, 4,   MMP2↓, 4,   MMP3↓, 1,   MMP9↓, 5,   MMPs↓, 2,   N-cadherin↓, 2,   TGF-β↓, 1,   TumCI↓, 4,   TumCMig↓, 4,   TumMeta↓, 3,   uPA↓, 2,   Vim↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 8,   Hif1a↓, 1,   NO↑, 1,   VEGF↓, 3,  

Barriers & Transport(tgid=15) ⓘ

MMP↓, 6,   MPT↑, 1,   TJ↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 5,   Eos↑, 1,   IL1β↓, 2,   IL2↓, 1,   Imm↑, 3,   Inflam↓, 1,   Inflam↝, 1,   M2 MC↓, 1,   Neut↑, 1,   NF-kB↓, 5,   NLRP3↓, 1,   PGE2↓, 1,   TNF-α↓, 2,   Treg lymp↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

ADAM10?, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 6,   BioAv↝, 2,   ChemoSen↑, 10,   DDS↑, 1,   Dose?, 1,   Dose↑, 4,   Dose↝, 2,   eff↓, 2,   eff↑, 7,   Half-Life↓, 1,   Half-Life↝, 1,   MDR1↓, 1,   RadioS↑, 3,   selectivity↑, 2,   Synergy↑, 6,  

Clinical Biomarkers(tgid=22) ⓘ

Tumccf↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 1,   AntiCan↑, 6,   AntiTum↑, 2,   cardioP↑, 2,   chemoP↑, 4,   hepatoP↑, 2,   neuroP↑, 1,   radioP↑, 2,   Risk↓, 4,   toxicity↓, 1,   TumVol↓, 1,   TumW↓, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 2,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 158

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 48,   Catalase↑, 2,   GPx↑, 4,   GSH↑, 9,   GSR↑, 1,   H2O2↓, 1,   HDL↑, 2,   HNE↓, 1,   HO-1↑, 3,   Keap1↓, 1,   lipid-P↓, 5,   MDA↓, 6,   MPO↓, 1,   NRF2↓, 1,   NRF2↑, 4,   ROS↓, 18,   ROS↑, 1,   SOD↑, 7,   TAC↑, 1,   TBARS↓, 1,   VitC↑, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,   IronCh↝, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

mitResp↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   ACSL4↓, 1,   adiP↓, 1,   ALDOA↑, 1,   ATP↑, 1,   CRM↑, 1,   GPI↑, 1,   HK2↑, 1,   LDHA↑, 1,   LDL↓, 2,   lipidLev↓, 1,   NAD↑, 1,   PFKL↑, 1,   PKM1↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   Casp3↓, 1,   Casp7↓, 1,   Fas↓, 1,   Ferroptosis↓, 1,   iNOS↓, 3,   iNOS↑, 1,   p‑p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 1,   ERK↑, 1,   JAK2↑, 1,   MAPK↓, 3,   mTOR↑, 1,   PI3K↓, 1,   PI3K↑, 1,   STAT3?, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   p‑cMyc↑, 1,   other↓, 1,   other↑, 1,   other↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1/ATG6↑, 1,   LC3B↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   PCNA↓, 1,   Telomerase↓, 1,   γH2AX↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 2,   LRP1↑, 1,   MUC1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 2,   NO↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 2,   BBB↑, 1,   CLDN1↑, 1,   CLDN3↑, 1,   GastroP↑, 1,   IBI↑, 1,   MMP↑, 1,   OCLN↑, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2/PTGS2↓, 4,   IFN-γ↓, 1,   IL10↑, 1,   IL1β↓, 4,   IL4↑, 1,   IL6↓, 5,   Imm↑, 3,   Inflam↓, 36,   NF-kB↓, 4,   NK cell↑, 1,   NLRP3↓, 3,   PGE2↓, 1,   TLR4↓, 1,   TNF-α↓, 6,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 5,   BChE↓, 1,   MAOA↓, 3,   MAOB↓, 1,  

Protein Aggregation(tgid=19) ⓘ

APP↓, 2,   Aβ↓, 4,   BACE/β-secretase↓, 2,   tau↓, 2,   p‑tau↓, 2,   XO↝, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 4,   BioAv↑, 5,   BioAv↝, 3,   CYP2C19↓, 1,   CYP2C9↓, 1,   Dose↝, 5,   eff↓, 3,   eff↑, 2,   eff↝, 2,   Half-Life↓, 1,   Half-Life↑, 2,   Half-Life↝, 1,   Synergy↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

BG↓, 1,   BMD↑, 1,   CRP↓, 2,   IL6↓, 5,   LDH↓, 1,   TC↓, 1,  

Functional Outcomes(tgid=23) ⓘ

antiAll↑, 1,   AntiArt↑, 2,   AntiCan↑, 3,   AntiDiabetic↑, 4,   AntiTum↓, 1,   AntiTum↑, 1,   BOLD↑, 1,   cardioP↑, 6,   cognitive↑, 6,   diuretic↑, 1,   hepatoP↓, 1,   hepatoP↑, 7,   memory↑, 6,   motorD↑, 2,   neuroP↓, 1,   neuroP↑, 15,   Obesity↓, 3,   Pain↓, 1,   radioP↑, 1,   Risk↓, 5,   Stress↓, 1,   Stroke↓, 1,   toxicity↓, 4,   toxicity∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 1,   AntiViral↑, 1,   Bacteria↓, 4,   GutMicro↑, 5,   GutMicro↝, 1,  
Total Targets: 157

Scientific Paper Hit Count for: antiOx, anti-oxidant activities
2 Chlorogenic acid
2 Geraniol
2 Piperine
2 Quercetin
2 Silymarin (Milk Thistle) silibinin
2 Thymoquinone
2 Urolithin
1 Anthocyanins
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 DTS(dibenzyl trisulphide) from Anamu
1 Anethole/trans-Anethole
1 Fennel Oil/Foeniculum vulgare
1 Baicalein
1 Berberine
1 Boron
1 α-Bisabolol / Chamomile oil
1 Carvacrol
1 chitosan
1 Curcumin
1 Dipyridamole
1 Aspirin
1 Dandelion Root
1 Eurycomanone
1 Eugenol
1 Fisetin
1 Fucoidan
1 Ginkgetin
1 Hydrogen Gas
1 Hydroxycinnamic-acid
1 Ferulic acid
1 Caffeic acid
1 Rosmarinic acid
1 Isobavachalcone
1 Isoliquiritigenin
1 Isorhamnetin
1 isoquercitrin
1 Kaempferol
1 Melatonin
1 Naringin
1 Oleocanthal
1 Phycocyanin
1 Pterostilbene
1 Resveratrol
1 Sesamin
1 Selenite (Sodium)
1 Terpinen-4-ol / Tea Tree Oil
1 cetuximab
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1103  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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