Cancer Database Query Results

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Scientific Papers found: Click to Expand⟱
4572- ,    Mitochondrial electron transport chain, ROS generation and uncoupling
- Review, NA, NA
*UCPs↝, *ETC↝, *ROS↝,
2432- 2DG,    Inhibition of glycolytic enzyme hexokinase II (HK2) suppresses lung tumor growth
- in-vitro, Lung, H23 - in-vitro, Lung, KP2 - in-vivo, NA, NA
HK2↓, Apoptosis↑, TumAuto↑, TumCG↓,
2433- 2DG,    Hexokinase inhibitor 2-deoxyglucose coordinates citrullination of vimentin and apoptosis of fibroblast-like synoviocytes by inhibiting HK2 /mTORC1-induced autophagy
- in-vitro, Arthritis, NA - in-vivo, NA, NA
Vim↓, HK2↓,
1337- 2DG,  Rad,    2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer
- in-vivo, NA, NA
ChemoSen↑, GlucoseCon↓, ROS↑,
1340- 3BP,    Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study
- Review, NA, NA
Glycolysis↓, HK2↓, LDH↓, OXPHOS↓, angioG↓, H2O2↑, eff↑,
1341- 3BP,    The HK2 Dependent “Warburg Effect” and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate
- Review, NA, NA
Glycolysis↓, OXPHOS↓, *toxicity↓, ROS↑, GSH↓, eff↑,
7857- 3BP,    A Mechanism of Isoorientin-Induced Apoptosis and Migration Inhibition in Gastric Cancer AGS Cells
- in-vitro, NA, AGS
tumCV↓, selectivity↑, *toxicity↓, Apoptosis↑, ROS↑, eff↓, TumCCA↑, p‑Akt↓, p‑GSK‐3β↓, β-catenin/ZEB1↓, TumCMig↓, Twist↓, N-cadherin↑, β-catenin/ZEB1↓, E-cadherin↑,
5263- 3BP,  CET,    3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis
- in-vitro, CRC, DLD1 - NA, NA, HCT116
eff↑, Ferroptosis↓, TumAuto↑, Apoptosis↑, FOXO3↑, AMPKα↑, p‑Beclin-1/ATG6↑, HK2↓, ATP↓, ROS↑, Dose↝, TumVol↓, TumW↓, xCT/SLC7A11↑, GSH↓, eff↓, MDA↑,
3537- 5-HTP,    5-Hydroxytryptophan: a clinically-effective serotonin precursor
- Review, NA, NA
*5HT↑, *BioAv↑, *BBB↑,
5301- 5-HTP,    Eosinophilia-myalgia syndrome presenting with overlapping features of eosinophilic fasciitis and sarcoidal granulomas
- Case Report, NA, NA
*toxicity↝, *toxicity↝,
1334- AG,    Astragalus membranaceus: A Review of Its Antitumor Effects on Non-Small Cell Lung Cancer
- Review, NA, NA
TumCP↓, Apoptosis↑, NF-kB↓, p50↓, cycD1/CCND1↓, Bcl-xL↓, ChemoSen↑, angioG↓, ChemoSen↑,
1097- AG,    Astragalus Inhibits Epithelial-to-Mesenchymal Transition of Peritoneal Mesothelial Cells by Down-Regulating β-Catenin
- in-vitro, Nor, HMrSV5 - in-vivo, NA, NA
*EMT↓, *E-cadherin↑, *α-SMA↓, *Vim↓, *β-catenin/ZEB1↓, *Smad7↑,
5438- AG,    Mechanisms of astragalus polysaccharide enhancing STM2457 therapeutic efficacy in mA-mediated OSCC treatment
- vitro+vivo, NA, NA
TumCP↓, TumCMig↓, TumCI↓, EMT↓, E-cadherin↑, N-cadherin↓,
1902- AgNPs,    Modulation of the mechanism of action of antibacterial silver N-heterocyclic carbene complexes by variation of the halide ligand
- in-vitro, NA, NA
TrxR↓, GSR↓, GSH↓,
4362- AgNPs,    Enhancing Colorectal Cancer Radiation Therapy Efficacy using Silver Nanoprisms Decorated with Graphene as Radiosensitizers
- in-vitro, CRC, HCT116 - in-vitro, CRC, HT29 - in-vivo, NA, NA
eff↑, TumCG↓, OS↑, RadioS↑, eff↑, ROS↑, DNAdam↑, eff↝,
4426- AgNPs,    Antiangiogenic properties of silver nanoparticles
- Study, NA, NA
angioG↑, TumCG↓, TumCI↓, TumMeta↓, VEGF↓, PI3K↓, Akt↓,
4432- AgNPs,    Emerging nanostructure-based strategies for breast cancer therapy: innovations, challenges, and future directions
- Review, NA, NA
ROS↑, TumCP↓, Apoptosis↑,
4377- AgNPs,    Interaction between silver nanoparticles of 20 nm (AgNP20 ) and human neutrophils: induction of apoptosis and inhibition of de novo protein synthesis by AgNP20 aggregates
- in-vitro, NA, NA
eff↑, Apoptosis↑,
4562- AgNPs,  VitC,    Eco-friendly Synthesis of Silver Nanoparticles using Ascorbic Acid and its Optical Characterization
- Study, NA, NA
*other↑, *other↝,
4557- AgNPs,    The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells
- in-vitro, NA, NIH-3T3 - in-vitro, CRC, HCT116
Cyt‑c↑, ROS↑, JNK↑,
4547- AgNPs,  GoldNP,  VitC,    Exploration of Biocompatible Ascorbic Acid Reduced and Stabilized Gold Nanoparticles, as Sensitive and Selective Detection Nanoplatform for Silver Ion in Solution
- Study, NA, NA
*eff↑,
4545- AgNPs,  VitC,  Citrate,    Ascorbic Acid-assisted Green Synthesis of Silver Nanoparticles: pH and Stability Study
- Study, NA, NA
*other↝, *other↝, *eff↑, *eff↑,
4542- AgNPs,    Silver Nanoparticles (AgNPs): Comprehensive Insights into Bio/Synthesis, Key Influencing Factors, Multifaceted Applications, and Toxicity─A 2024 Update
- Review, NA, NA
AntiCan↑, DNAdam↑, ATP↓, Apoptosis↑, ROS↓, TumCCA↑, *Bacteria↓, *BMD↑,
4574- AgNPs,    Advances in nano silver-based biomaterials and their biomedical applications
- Review, NA, NA
*Wound Healing↑, *AntiThr↑, *AntiAg↑, eff↑,
4596- AgNPs,    Oral administration of silver nanomaterials affects the gut microbiota and metabolic profile altering the secretion of 5-HT in mice
- in-vivo, NA, NA
*GutMicro↝, *5HT↑,
4595- AgNPs,    ORAL DELIVERY OF SILVER NANOPARTICLES – A REVIEW
- Review, NA, NA
*BioAv↝,
4592- AgNPs,  Chit,    Chitosan conjugated silver nanoparticles: the versatile antibacterial agents
- in-vitro, NA, NA
*Bacteria↓,
4591- AgNPs,  Chit,    Synthesis and Characterization of Multifunctional Chitosan–Silver Nanoparticles: An In-Vitro Approach for Biomedical Applications
- in-vitro, NA, NA
*Bacteria↓, *Wound Healing↑,
4590- AgNPs,  Chit,    Silver nanochitosan: a sustainable approach for enhanced antimicrobial, antioxidant, and anticancer applications
- in-vitro, NA, NA
*Bacteria↓, *Wound Healing↑,
4589- AgNPs,  Chit,    Synthesis and Characterization of Chitosan–Silver Nanocomposite Film: Antibacterial and Cytotoxicity Study
- in-vitro, NA, NA
*Bacteria↓,
4588- AgNPs,  Chit,    Solid-state tailored silver nanocomposites from chitosan: Synthesis, antimicrobial evaluation and molecular docking
- in-vitro, NA, NA
*Bacteria↓,
4587- AgNPs,  Chit,    Multifunctional Silver Nanoparticles Based on Chitosan: Antibacterial, Antibiofilm, Antifungal, Antioxidant, and Wound-Healing Activities
- in-vitro, NA, NA
*Bacteria↓, *Wound Healing↑,
4583- AgNPs,    Metal-Based Nanoparticles for Cardiovascular Diseases
- Review, NA, NA
RadioS↑, *ROS↑, *BBB↝,
4580- AgNPs,    Biogenic Synthesis of Antibacterial, Hemocompatible, and Antiplatelets Lysozyme Functionalized Silver Nanoparticles through the One-Step Process for Therapeutic Applications
- in-vitro, NA, NA
*AntiAg↑,
4578- AgNPs,    Green synthesized novel silver nanoparticles and their application as anticoagulant and thrombolytic agents: A perspective
- Review, NA, NA
*AntiThr↑,
4576- AgNPs,    Nanosilver, Next-Generation Antithrombotic Agent
- Study, NA, NA
*AntiAg↑, *Bacteria↓,
4573- AgNPs,    Bioactive silver nanoparticles derived from Carica papaya floral extract and its dual-functioning biomedical application
- in-vitro, Var, MCF7 - NA, NA, HEK293
toxicity↓, Bacteria↓, selectivity↑,
342- AgNPs,    Silver nanoparticles; a new hope in cancer therapy?
- Review, NA, NA
ROS↑, DNAdam↑, Apoptosis↑, mtDam↑,
337- AgNPs,  immuno,    Silver nanoparticle induced immunogenic cell death can improve immunotherapy
- Review, NA, NA
PD-L1↓,
335- AgNPs,  PDT,    Biogenic Silver Nanoparticles for Targeted Cancer Therapy and Enhancing Photodynamic Therapy
- Review, NA, NA
ROS↑, GSH↓, GPx↑, Catalase↓, SOD↓, p38↑, BAX↑, Bcl-2↓,
375- AgNPs,  ALA,    Alpha-Lipoic Acid Prevents Side Effects of Therapeutic Nanosilver without Compromising Cytotoxicity in Experimental Pancreatic Cancer
- in-vitro, PC, Bxpc-3 - in-vitro, PC, PANC1 - in-vitro, PC, MIA PaCa-2 - in-vivo, NA, NA
mtDam↑, ROS↑, *toxicity↓, Dose∅, selectivity↑,
321- AgNPs,    I-131 doping of silver nanoparticles platform for tumor theranosis guided drug delivery
- in-vivo, NA, NA
other↑,
320- AgNPs,    Silver nanoparticles induce endoplasmatic reticulum stress response in zebrafish
- vitro+vivo, NA, HUH7
ROS↑, ER Stress↑, TNF-α↑,
309- AgNPs,    Interference of silver, gold, and iron oxide nanoparticles on epidermal growth factor signal transduction in epithelial cells
- in-vitro, NA, A431
ROS↑, Akt↓, p‑ERK↓,
306- AgNPs,    Cancer Therapy by Silver Nanoparticles: Fiction or Reality?
- Analysis, NA, NA
EPR↝, ROS↑, IL1↑, IL8↑, ER Stress↑, MMP9↑, MMP↓, Cyt‑c↑, Apoptosis↑, Hif1a↑, BBB↑, GutMicro↝, eff↑, eff↑, RadioS↑,
374- AgNPs,    Silver nanoparticles selectively treat triple‐negative breast cancer cells without affecting non‐malignant breast epithelial cells in vitro and in vivo
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
ER Stress↑, DNAdam↑, ROS↑, Apoptosis↑, GSH/GSSG↓, NADPH/NADP+↓, TumCG↓, UPR↑,
367- AgNPs,    Presence of an Immune System Increases Anti-Tumor Effect of Ag Nanoparticle Treated Mice
- in-vivo, NA, NA
ROS↑, mtDam↑, TumCG↓,
347- AgNPs,    The Role of Silver Nanoparticles in the Diagnosis and Treatment of Cancer: Are There Any Perspectives for the Future?
- Review, NA, NA
ROS↑, Apoptosis↑, ER Stress↑,
355- AgNPs,    Cytotoxicity and Genotoxicity of Biogenic Silver Nanoparticles in A549 and BEAS-2B Cell Lines
- in-vitro, Lung, A549 - in-vitro, NA, BEAS-2B
ROS↑, DNAdam↑, Apoptosis↑,
403- AgNPs,  RF,    Synergetic effects of silver and gold nanoparticles in the presence of radiofrequency radiation on human kidney cells
- in-vitro, NA, HNK
Apoptosis↝,

Showing Research Papers: 1 to 50 of 838
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 838

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

ABCG1↓, 1,   compII↓, 1,   CYP2D6↓, 1,   DHODH↓, 1,   H3K9↓, 1,   NA↑, 1,   PRMT6↓, 1,   SUV39H↓, 1,   UGT1A↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 7,   Bil∅, 1,   Catalase↓, 7,   Catalase↑, 1,   compI↓, 1,   CYP1A1↓, 1,   CYP1A1↑, 1,   CYP2E1↓, 1,   ENOX2↓, 1,   Fenton↑, 11,   Ferroptosis↓, 1,   Ferroptosis↑, 6,   frataxin↑, 1,   GPx↓, 2,   GPx↑, 1,   GPx4↓, 3,   GSH↓, 27,   GSH/GSSG↓, 2,   GSR↓, 2,   GSTP1/GSTπ↓, 1,   H2O2?, 1,   H2O2↑, 17,   e-H2O2↓, 1,   i-H2O2∅, 1,   HDL↓, 1,   HNE↑, 1,   HO-1↓, 1,   HO-1↑, 3,   ICD↑, 1,   Iron↑, 2,   Iron↝, 1,   i-Iron↓, 1,   ox-Keap1↓, 1,   rd-Keap1↑, 1,   lipid-P↓, 3,   lipid-P↑, 5,   MDA↑, 2,   MGO↑, 1,   MPO↓, 1,   NADHdeh↓, 1,   NADPH/NADP+↓, 1,   NAF1↓, 1,   NQO1?, 1,   NQO1↑, 2,   NRF2↓, 6,   NRF2↑, 12,   NRF2∅, 1,   OSI↑, 1,   OXPHOS↓, 5,   OXPHOS↑, 3,   mt-OXPHOS↑, 1,   PARK2↑, 1,   Prx↓, 1,   Prx4↓, 1,   RNS↓, 1,   ROMO1↑, 1,   ROS?, 1,   ROS↓, 6,   ROS↑, 181,   ROS⇅, 5,   ROS↝, 1,   i-ROS↑, 2,   mt-ROS↑, 3,   RPM↑, 2,   SAM-e↑, 1,   SAM-e↝, 2,   selenoP↑, 1,   SIRT3↓, 1,   SIRT3↑, 1,   SOD↓, 6,   SOD↑, 5,   SOD2↑, 1,   TOS↑, 1,   Trx↓, 2,   Trx1↓, 1,   TrxR↓, 2,   TrxR1↓, 1,   xCT/SLC7A11↓, 3,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 2,   TfR1/CD71↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 3,   ATP↓, 19,   ATP↑, 1,   CDC25↓, 1,   EGF↓, 1,   Insulin↓, 1,   MEK↓, 2,   p‑MEK↓, 1,   mitResp↓, 1,   MKK4↓, 1,   MMP↓, 42,   MMP↑, 1,   MPT↓, 1,   MPT↑, 1,   mtDam↑, 14,   OCR↓, 6,   OCR↑, 2,   PGC-1α↑, 1,   PINK1↑, 1,   Raf↓, 2,   e-Raf↓, 1,   SDH↓, 1,   XIAP↓, 9,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   6PGD↓, 1,   ACC1↓, 2,   ACLY↓, 7,   ACSS2↓, 1,   ALAT↓, 3,   ALAT∅, 1,   ALDOAiso2↓, 1,   AminoA↓, 1,   AMP↓, 1,   AMP↑, 1,   AMPK↑, 11,   p‑AMPK↑, 2,   ATG7↑, 2,   ATP:AMP↓, 1,   CAIX/CA9↓, 2,   Cav1↑, 1,   i-citrate↑, 1,   cMyc↓, 15,   CPT1A↓, 2,   p‑CREB↓, 1,   ECAR↓, 6,   ECAR∅, 1,   FABP4↑, 1,   FASN↓, 8,   G6PD∅, 1,   GAPDH↓, 1,   GLO-I↓, 1,   GLS↓, 1,   glucose↓, 1,   GlucoseCon↓, 17,   glut↓, 1,   GLUT2↓, 2,   GlutMet↓, 1,   Glycolysis↓, 36,   Glycolysis↑, 1,   HK2↓, 19,   HK2∅, 1,   IDH1↑, 1,   lactateProd↓, 22,   LAT↓, 1,   LDH↓, 4,   LDHA↓, 15,   LDHA∅, 1,   LDL↓, 2,   lipoGen↓, 1,   NAD↓, 3,   NAD↝, 1,   NADPH↓, 1,   NADPH↑, 1,   NPC1L1↓, 1,   p‑PCK1↓, 1,   PDH↑, 4,   p‑PDH↓, 1,   PDK1 / PDPK1↓, 5,   p‑PDK1 / PDPK1↓, 2,   PDKs↓, 3,   PFK↓, 3,   PFK1↓, 4,   PFK2↓, 1,   PFKP↓, 2,   PGK1↓, 1,   PI3K/Akt↓, 4,   PI3K/Akt↑, 1,   PI3K/Akt↝, 1,   PI3k/Akt/mTOR↓, 1,   PKL↓, 1,   PKM2↓, 19,   PKM2∅, 1,   p‑PKM2↓, 2,   PPARα↑, 1,   PPARα↝, 1,   PPARγ↑, 2,   PPP↓, 1,   PSMB5↓, 1,   RNR↓, 1,   RPSA↓, 1,   p‑S6↓, 1,   SIRT1↓, 2,   SIRT1↑, 3,   SIRT2↓, 1,   SREBP1/SREBF1?, 1,   SREBP1/SREBF1↓, 2,   TCA↓, 1,   Warburg↓, 7,   β-oxidation↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 40,   Akt↑, 1,   p‑Akt↓, 20,   APAF1↑, 1,   Apoptosis?, 1,   Apoptosis↓, 1,   Apoptosis↑, 132,   Apoptosis↝, 1,   mt-Apoptosis↑, 1,   ASK1↑, 1,   autoS↑, 1,   BAD↓, 1,   BAD↑, 3,   Bak↑, 5,   BAX↑, 50,   Bax:Bcl2↑, 9,   Bcl-2↓, 54,   Bcl-2↑, 1,   Bcl-xL↓, 17,   BID↑, 3,   BIM↑, 1,   BMP2↓, 1,   BTG3↑, 1,   Casp↑, 11,   Casp1↓, 3,   cl‑Casp1↑, 1,   proCasp1↓, 1,   Casp12↑, 2,   cl‑Casp12↝, 1,   Casp2↑, 1,   Casp3?, 1,   Casp3↑, 50,   Casp3∅, 1,   cl‑Casp3↑, 9,   proCasp3↑, 1,   Casp7?, 1,   Casp7↑, 5,   Casp8↑, 10,   Casp8∅, 1,   Casp9?, 1,   Casp9↑, 32,   cl‑Casp9↑, 1,   cFLIP↓, 2,   Chk2↑, 1,   p‑Chk2↓, 1,   p‑Chk2↑, 2,   CK2↓, 1,   Cupro↑, 2,   Cyt‑c↑, 32,   Cyt‑c↝, 1,   DR4↑, 1,   DR5↑, 5,   FADD↑, 1,   Fas↑, 2,   FasL↑, 1,   Ferroptosis↓, 1,   Ferroptosis↑, 6,   cl‑GSDMD↑, 1,   GSDME-N↑, 2,   HGF/c-Met↓, 2,   hTERT/TERT↓, 4,   IAP1↓, 2,   IAP2/BIRC3↓, 1,   iNOS↓, 8,   JNK↓, 1,   JNK↑, 7,   p‑JNK↓, 3,   p‑JNK↑, 4,   JWA↑, 1,   MAPK↓, 10,   MAPK↑, 9,   MAPK↝, 1,   p‑MAPK↑, 1,   Mcl-1↓, 8,   MCT1↓, 1,   MDM2↓, 2,   MLKL↑, 1,   p‑MLKL↓, 1,   Myc↓, 1,   Necroptosis↑, 5,   necrosis↑, 3,   oncosis↑, 2,   p27/CDKN1B↑, 7,   P2X7↓, 1,   p38↓, 4,   p38↑, 6,   p‑p38↓, 2,   p‑p38↑, 3,   Paraptosis↑, 3,   PPP2R1A↑, 1,   Proteasome↓, 1,   Pyro↑, 4,   RIP1↑, 2,   p‑RSK↓, 1,   survivin↓, 19,   Telomerase↓, 6,   TRAIL↑, 2,   TumCD↑, 12,   TUNEL↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

AMPKα↑, 2,   p‑p70S6↓, 1,   SOX9↓, 1,   SOX9↑, 1,   Sp1/3/4↓, 6,  

Transcription & Epigenetics(tgid=7) ⓘ

carcinogenesis↓, 1,   cJun↓, 1,   H3↓, 1,   ac‑H3↑, 4,   ac‑H4↑, 4,   HATs↓, 5,   HATs↑, 1,   KISS1↑, 1,   miR-21↓, 1,   other?, 2,   other↓, 10,   other↑, 13,   other↝, 11,   other∅, 4,   p‑pRB↓, 1,   PRC2↓, 1,   Prot↝, 1,   sonoS↑, 1,   tumCV?, 1,   tumCV↓, 31,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 2,   cl‑ATF6↑, 1,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 10,   p‑CHOP/DDIT3↝, 1,   eIF2α↑, 4,   p‑eIF2α↓, 1,   p‑eIF2α↑, 6,   p‑eIF2α↝, 1,   ER Stress↑, 26,   GRP78/BiP↑, 6,   GRP94↑, 1,   HRI↓, 1,   p‑Hsc70↑, 1,   HSP27↓, 1,   HSP70/HSPA5↓, 3,   HSP70/HSPA5↑, 2,   HSP72↓, 1,   HSP90↓, 5,   ac‑HSP90↑, 1,   HSPs∅, 1,   p‑IRE1↓, 1,   PERK↓, 1,   PERK↑, 4,   p‑PERK↝, 1,   UPR↑, 5,   mt-UPR↑, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1/ATG6↑, 2,   p‑Beclin-1/ATG6↑, 1,   BNIP3↑, 2,   BNIP3↝, 1,   LC3B↓, 1,   LC3B↑, 2,   LC3B-II↑, 2,   LC3II↑, 3,   p62↓, 2,   p62↑, 2,   TumAuto↓, 1,   TumAuto↑, 23,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p‑ATM↑, 1,   p‑ATR↑, 1,   BRCA1↑, 1,   BRCA2↓, 2,   CHK1↑, 1,   p‑CHK1↑, 1,   DNAdam↓, 1,   DNAdam↑, 37,   DNArepair↑, 1,   DNMT1↓, 9,   DNMT3A↓, 3,   DNMTs↓, 8,   G9a↓, 1,   GADD45A↑, 1,   HR↓, 1,   importin α/β↓, 1,   MGMT↓, 1,   NKX3.1↓, 1,   p16↑, 3,   P53?, 1,   P53↓, 1,   P53↑, 32,   P53↝, 1,   p‑P53↓, 1,   p‑P53↑, 2,   PARP↑, 9,   PARP∅, 1,   p‑PARP↑, 1,   cl‑PARP↑, 12,   cl‑PARP1↑, 1,   PCNA↓, 3,   RAD51↓, 1,   SIRT6↓, 1,   TP53↑, 2,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 2,   CDK2↓, 2,   CDK2↑, 1,   CDK4↓, 2,   CDK4↑, 1,   Cyc↓, 1,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 2,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 22,   cycD1/CCND1↑, 1,   cycE/CCNE↓, 2,   cycE1↓, 1,   E2Fs↓, 1,   p19↑, 1,   P21↓, 1,   P21↑, 20,   TumCCA↑, 70,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   AR-FL↓, 1,   AR-V7↑, 1,   AXIN1↑, 1,   BMI1↓, 1,   BRAF↝, 1,   CD133↓, 2,   CD24↓, 2,   CD44↓, 3,   cMET↓, 2,   CREBBP↓, 1,   CSCs↓, 9,   Diff↑, 4,   EMT?, 1,   EMT↓, 33,   ERK↓, 23,   ERK↑, 4,   p‑ERK↓, 10,   p‑ERK↑, 3,   p‑ERK⇅, 1,   ERK5↑, 1,   FGF↓, 1,   FOXM1↓, 1,   FOXO↓, 1,   FOXO1↑, 1,   FOXO3↓, 1,   FOXO3↑, 2,   Gli1↓, 2,   GSK‐3β↓, 1,   GSK‐3β↑, 1,   GSK‐3β↝, 1,   p‑GSK‐3β↓, 3,   GTPBP4↓, 1,   HDAC↓, 22,   HDAC1↓, 6,   HDAC10↑, 1,   HDAC11↓, 1,   HDAC2↓, 2,   HDAC3↓, 5,   HDAC4↓, 1,   HDAC8↓, 4,   IGF-1↓, 7,   IGF-1R↓, 3,   p‑IGF-1R↓, 1,   IGFBP3↓, 1,   IGFBP3↑, 2,   IGFR↓, 1,   Let-7↑, 5,   LRP6↓, 1,   mTOR↓, 21,   mTOR↑, 4,   p‑mTOR↓, 4,   Nanog↓, 4,   Nestin↓, 2,   NOTCH↓, 1,   NOTCH1↓, 2,   NOTCH1↝, 1,   OCT4↓, 3,   p300↓, 2,   P70S6K↓, 1,   P70S6K↑, 1,   p‑P70S6K↓, 1,   p‑P90RSK↑, 1,   PI3K↓, 24,   PI3K↑, 1,   p‑PI3K↓, 2,   PTEN↓, 1,   PTEN↑, 9,   PTEN↝, 1,   RAS↓, 2,   Shh↓, 1,   SOX2↓, 1,   c-Src↓, 1,   STAT↓, 1,   STAT1↓, 1,   STAT3↓, 28,   STAT3↑, 1,   p‑STAT3↓, 6,   STAT5↓, 1,   p‑STAT5↓, 1,   TCF↓, 4,   TOP1↓, 3,   TOP1↝, 1,   TOP1∅, 1,   TOP2↓, 1,   TOP2↑, 1,   TRPM7↑, 1,   TumCG?, 1,   TumCG↓, 80,   TumCG↑, 1,   VGCC↑, 1,   Wnt?, 1,   Wnt↓, 9,   Wnt/(β-catenin)↓, 5,   Wnt/(β-catenin)↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 3,   67LR↓, 1,   Akt2↓, 1,   AntiAg↓, 1,   AntiAg↑, 7,   AP-1↓, 3,   AP-1↑, 1,   AP-1↝, 1,   APP↓, 1,   ATPase↓, 1,   CA↓, 1,   Ca+2↓, 2,   Ca+2↑, 12,   CCN2/CTGF↓, 1,   CD11b↑, 1,   CD31/PECAM-1↑, 1,   Cdc42↓, 1,   CDK4/6↓, 1,   CXCL12↓, 1,   E-cadherin↓, 2,   E-cadherin↑, 25,   EM↑, 1,   F-actin↓, 1,   FAK↓, 5,   FAK↑, 1,   Fibronectin↓, 1,   Fibrosis↓, 1,   GLI2↓, 1,   hnRNPA1↓, 1,   ITGA5↓, 1,   ITGB1↓, 2,   ITGB1↑, 1,   ITGB3↓, 1,   Ki-67↓, 7,   Ki-67↑, 1,   KRAS↓, 1,   L-sel↑, 1,   LEF1↓, 1,   LysoPr↑, 1,   MALAT1↓, 1,   MET↑, 1,   miR-139-5p↑, 1,   miR-155↓, 2,   miR-200b↑, 1,   miR-200c↑, 2,   miR-203↓, 1,   miR-203↑, 1,   MMP1↑, 1,   MMP2↓, 23,   MMP3↓, 1,   MMP3↑, 1,   MMP7↓, 1,   MMP9↓, 29,   MMP9↑, 2,   MMPs↓, 8,   N-cadherin↓, 9,   N-cadherin↑, 1,   NCAM↑, 1,   NFAT↑, 1,   PDGF↓, 1,   PKA↓, 2,   PKCδ↓, 1,   PKCδ↑, 1,   RECK↑, 1,   Rho↓, 2,   RIP3↑, 3,   p‑RIP3↑, 1,   SA↓, 1,   SDC1↑, 1,   serineP↓, 1,   Slug↓, 6,   p‑SMAD2↓, 1,   Snail↓, 14,   Snail↑, 1,   TET1↑, 2,   TGF-β↓, 8,   TGF-β↑, 1,   TIMP1↑, 2,   TIMP2↑, 3,   TIMP3↑, 1,   Treg lymp↓, 4,   TumCI?, 1,   TumCI↓, 32,   TumCI↑, 1,   TumCMig↓, 39,   TumCP↓, 70,   TumCP↑, 1,   TumMeta↓, 18,   Twist↓, 5,   Twist↑, 1,   TXNIP↓, 1,   uPA↓, 2,   VCAM-1↓, 1,   Vim↓, 19,   Zeb1↓, 5,   ZEB2↓, 1,   ZEB2↑, 2,   ZO-1↑, 1,   α-SMA↓, 2,   β-catenin/ZEB1↓, 19,   β-catenin/ZEB1↑, 1,   p‑β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 26,   angioG↑, 4,   ATF4↑, 6,   p‑ATF4↝, 1,   EGFR↓, 18,   p‑EGFR↓, 2,   eNOS↓, 1,   eNOS↑, 1,   EPR↑, 2,   EPR↝, 1,   HIF-1↓, 5,   HIF-1↑, 1,   Hif1a↓, 35,   Hif1a↑, 2,   Hif1a↝, 2,   miR-210↓, 1,   miR-210↑, 1,   NO↓, 2,   NO↑, 4,   PDGFR-BB↑, 1,   TAMS↓, 1,   TXA2↓, 1,   TXA2↑, 1,   VEGF↓, 42,   VEGF↑, 1,   VEGFR2/KDR/Flk1↓, 5,   VM↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,   CellMemb↓, 1,   CellMemb↑, 4,   CTR1↑, 1,   GLUT1↓, 10,   GLUT3↓, 1,   GLUT4↓, 3,   NHE1↓, 2,   OATPs↓, 1,   P-gp/ABCB1↓, 2,   P-gp/ABCB1↑, 1,   SLC12A5↓, 1,   SVCT-2↝, 1,   SVCT-2∅, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ASC↓, 1,   CD25+↓, 3,   CD4+↓, 4,   CD4+↑, 1,   COX1↓, 3,   COX2/PTGS2↓, 25,   COX2/PTGS2↑, 2,   COX2/PTGS2↝, 1,   CR3↝, 1,   CRP↓, 3,   CXCL1↓, 1,   CXCR2↓, 1,   CXCR4↓, 4,   DCells↑, 1,   FOXP3↓, 1,   FoxP3+↓, 3,   ICAM-1↓, 1,   IFN-γ↓, 3,   IFN-γ↑, 1,   IKKα↓, 2,   IKKα↑, 2,   p‑IKKα↓, 1,   IL1↓, 6,   IL1↑, 2,   IL10↓, 3,   IL10↑, 2,   IL18↓, 1,   IL1α↓, 1,   IL1β↓, 7,   IL2↓, 1,   IL4↓, 1,   IL4↑, 1,   IL6↓, 15,   IL8↓, 3,   IL8↑, 3,   IL9↓, 1,   Imm↑, 2,   INF-γ↓, 1,   Inflam↓, 9,   IκB↑, 2,   p‑IκB↓, 1,   JAK↓, 1,   JAK2↓, 5,   LTA/TNF-β↓, 1,   M2 MC↑, 1,   MIP2↓, 1,   NF-kB↓, 46,   NF-kB↑, 2,   NK cell↑, 2,   p50↓, 2,   p65↓, 2,   PD-1↝, 1,   PD-L1↓, 9,   PD-L1↑, 1,   PGD2↓, 1,   PGE2↓, 4,   PSA↓, 9,   SOCS1↑, 1,   T-Cell↓, 1,   T-Cell↑, 4,   Th1 response↓, 1,   Th2↑, 1,   TNF-α↓, 19,   TNF-α↑, 2,   TNF-α∅, 1,   VitD↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

IM↓, 1,   pH↓, 2,   pH↑, 1,   pH↝, 1,   TIM-3↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   GABA↑, 1,   tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 3,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 9,   CDK6↓, 1,   CYP19↓, 1,   DHT↑, 1,   ER(estro)↓, 2,   ERα/ESR1↓, 1,   ERα/ESR1↑, 1,   ERβ/ESR2↑, 1,   EstroRS/ERS↓, 1,   FKBP5↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 15,   BioAv↑, 10,   BioAv↝, 3,   BioAv∅, 1,   BioEnh↑, 1,   BioEnh↝, 1,   chemoR↓, 1,   ChemoSen↑, 43,   ChemoSen⇅, 1,   ChemoSen∅, 1,   CYP2C9↓, 2,   Dose?, 3,   Dose↓, 1,   Dose↑, 2,   Dose↝, 28,   Dose∅, 16,   eff?, 1,   eff↓, 39,   eff↑, 120,   eff⇅, 1,   eff↝, 11,   eff∅, 1,   Half-Life↓, 1,   Half-Life↝, 6,   Half-Life∅, 3,   MDR1↓, 1,   MRP1/ABCC1↑, 1,   P450↓, 1,   RadioS↑, 14,   selectivity?, 1,   selectivity↓, 2,   selectivity↑, 55,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 3,   ALAT∅, 1,   Albumin↝, 1,   ALP↓, 1,   AR↓, 9,   AST↓, 2,   AST∅, 1,   BG↓, 1,   Bil∅, 1,   BMD↓, 1,   BMPs↑, 1,   BP↓, 1,   BRAF↝, 1,   BRCA1↑, 1,   CA125↓, 1,   Calcium↑, 1,   CRP↓, 3,   CTC↓, 1,   E6↓, 2,   E7↓, 2,   EGFR↓, 18,   p‑EGFR↓, 2,   ERα/ESR1↓, 1,   ERα/ESR1↑, 1,   EstroRS/ERS↓, 1,   FOXM1↓, 1,   GutMicro↑, 7,   GutMicro↝, 2,   hTERT/TERT↓, 4,   IL6↓, 15,   Ki-67↓, 7,   Ki-67↑, 1,   KRAS↓, 1,   LDH↓, 4,   Myc↓, 1,   NOS2↓, 1,   PD-L1↓, 9,   PD-L1↑, 1,   PSA↓, 9,   TP53↑, 2,   VitD↑, 1,   XIST↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 24,   antiNeop↑, 1,   AntiTum↑, 17,   cardioP↑, 6,   chemoP↑, 15,   chemoPv↑, 3,   ChemoSideEff↓, 14,   cognitive↑, 1,   hepatoP↑, 4,   K17↓, 1,   memory↑, 4,   neuroP↑, 6,   OS↓, 2,   OS↑, 23,   Pain↓, 1,   QoL↑, 3,   radioP↑, 6,   Remission↓, 1,   Remission↑, 3,   RenoP↑, 3,   Risk↓, 20,   Risk↝, 1,   Risk∅, 1,   toxicity↓, 7,   toxicity⇅, 1,   toxicity↝, 5,   toxicity∅, 5,   TumVol↓, 41,   TumW↓, 17,   UBE2C↓, 1,   Weight↓, 1,   Weight∅, 2,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 3,   CD8+↑, 2,  
Total Targets: 852

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,   Ast↓, 1,   CES2↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx?, 1,   antiOx↓, 2,   antiOx↑, 57,   Bil↓, 1,   Catalase↓, 1,   Catalase↑, 10,   Catalase↝, 1,   Copper↓, 1,   CoQ10↑, 1,   Fenton↓, 2,   Ferroptosis↓, 2,   Ferroptosis↑, 1,   GCLC↑, 1,   GPx↓, 1,   GPx↑, 12,   GPx4↓, 1,   GPx4↑, 2,   GSH↓, 2,   GSH↑, 20,   GSR↓, 1,   GSR↑, 3,   GSSG↓, 2,   GSTA1↑, 2,   GSTs↓, 1,   GSTs↑, 3,   H2O2↓, 1,   HDL↑, 1,   HO-1↓, 2,   HO-1↑, 17,   HO-1↝, 1,   Iron↓, 5,   i-Iron↑, 1,   Keap1↓, 1,   ox-Keap1↑, 1,   lipid-P?, 1,   lipid-P↓, 15,   lipid-P↑, 1,   MDA↓, 20,   MDA↑, 2,   MPO↑, 1,   MPOD↑, 3,   NOX4↓, 1,   NQO1↑, 4,   Nrf1?, 1,   NRF2↓, 1,   NRF2↑, 28,   Prx↑, 1,   Prx4∅, 1,   RNS↓, 1,   ROMO1↑, 1,   ROS↓, 81,   ROS↑, 10,   ROS⇅, 3,   ROS↝, 2,   ROS∅, 2,   RPM↑, 1,   selenoP↑, 2,   SOD↓, 2,   SOD↑, 19,   SOD↝, 1,   SOD1↑, 3,   SOD2↑, 1,   TAC↑, 2,   Thiols↑, 1,   Trx↑, 2,   Trx1↑, 1,   TrxR↑, 1,   UCPs↝, 1,   uricA↓, 1,   VitC↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

FTH1↑, 1,   FTL↓, 1,   IronCh↑, 6,   NCOA4↝, 1,   TfR1/CD71↓, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 3,   ETC↓, 2,   ETC↑, 1,   ETC↝, 1,   Insulin↑, 1,   MMP↑, 5,   MMP⇅, 1,   OCR↑, 1,   PGC-1α↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

Acetyl-CoA↑, 1,   adiP↑, 1,   p‑AKT1↑, 1,   ALAT↓, 8,   ALAT↑, 1,   AMPK↑, 3,   AMPK↝, 1,   BUN↓, 3,   cPLA2↓, 1,   CREB↑, 11,   CREB∅, 1,   p‑CREB↑, 2,   ECAR↓, 1,   FAO↑, 1,   FASN↓, 1,   glucose↓, 1,   GlucoseCon↓, 1,   GlucoseCon↑, 2,   Glycolysis↓, 2,   Glycolysis↑, 2,   HK2↓, 3,   lactateProd↓, 1,   LDH↓, 3,   LDHA↓, 1,   LDL↓, 5,   lipoGen↓, 1,   NAD↑, 1,   NADPH↓, 2,   NADPH↑, 2,   NH3↓, 1,   PFK↓, 1,   PFK1↓, 1,   PKM2↓, 3,   PPARα↑, 1,   PPARγ↑, 2,   SIRT1↑, 11,   SIRT2↑, 1,   SREBP1/SREBF1↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 4,   Akt↝, 1,   p‑Akt↓, 2,   p‑Akt↑, 4,   Apoptosis↓, 12,   Bax:Bcl2↓, 2,   Bcl-2↑, 1,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 7,   Casp3↑, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   Ferroptosis↓, 2,   Ferroptosis↑, 1,   GRP58↓, 1,   HEY1↑, 1,   HGF/c-Met↑, 1,   iNOS↓, 13,   iNOS↑, 2,   JNK↑, 1,   MAPK↓, 5,   MAPK↑, 1,   MAPK↝, 1,   necrosis↓, 2,   p38↓, 1,   p38↑, 1,   p‑p38↓, 2,   Pyro?, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Sp1/3/4↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 4,   AntiThr↑, 3,   p‑cJun↓, 1,   other?, 2,   other↓, 5,   other↑, 14,   other↝, 17,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 3,   ER Stress↓, 9,   GRP78/BiP↓, 4,   HSP27↑, 1,   HSPs↓, 1,   HSPs↑, 2,   PERK↓, 2,   UPR↓, 1,   XBP-1↓, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   p62↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,   DNArepair↑, 1,   P53↓, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

E2Fs↑, 2,   P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EMT↓, 2,   EMT↑, 1,   ERK↓, 1,   ERK↑, 6,   p‑ERK↓, 2,   FGF↑, 3,   p‑GSK‐3β↑, 1,   HDAC↓, 3,   HDAC2↓, 1,   IGF-1↑, 1,   IGF-1R↓, 1,   mTOR↓, 2,   mTOR↑, 1,   mTOR↝, 2,   p‑mTOR↓, 1,   neuroG↑, 2,   NOTCH↑, 1,   OCT4↓, 1,   PI3K↓, 1,   PI3K↑, 4,   PI3K↝, 1,   Src↓, 1,   STAT↓, 1,   STAT3?, 1,   STAT3↓, 1,   TRPM7↝, 1,   TumCG∅, 1,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AntiAg↑, 20,   AP-1↓, 2,   APP↓, 1,   mt-ATPase↑, 1,   Ca+2↓, 3,   Ca+2↑, 4,   Ca+2↝, 2,   cal2↓, 2,   CEA↓, 1,   E-cadherin↑, 3,   F-actin↓, 1,   FAK↑, 1,   ITGB1↑, 1,   MMP13↓, 1,   MMP2↓, 3,   MMP2↑, 2,   MMP9↓, 1,   MMP9↑, 3,   MMPs↓, 1,   MMPs↑, 2,   N-cadherin↓, 1,   PDGF↓, 1,   PDGF↑, 1,   PKA↑, 1,   PKCδ?, 1,   ROCK1↓, 1,   Sema3A/PlexinA1↑, 1,   SMAD4↑, 1,   SMAD5↑, 1,   Smad7↑, 1,   Snail↓, 1,   TG2/TGase↓, 1,   TGF-β↓, 4,   TGF-β↑, 2,   TIMP1↓, 1,   TIMP1↑, 2,   TumCMig↓, 1,   Vim↓, 3,   ZO-1↑, 1,   α-SMA↓, 4,   β-catenin/ZEB1↓, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   angioG↑, 6,   ATF4↓, 1,   EGFR↓, 1,   eNOS↓, 1,   eNOS↑, 1,   Hif1a↓, 2,   Hif1a↑, 4,   LOX1↓, 1,   NO↓, 7,   NO↑, 1,   PDGFR-BB↓, 1,   TXA2↓, 2,   VEGF↓, 3,   VEGF↑, 9,   VEGFR2/KDR/Flk1↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 11,   BBB↝, 1,   GLUT4↑, 1,   MRP↓, 1,   OATPs↓, 2,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ASC?, 1,   COX1↓, 3,   COX2/PTGS2↓, 14,   CRP↓, 1,   IFN-γ↓, 4,   IL1↓, 2,   IL1↑, 1,   IL10↓, 2,   IL10↑, 2,   IL17↓, 2,   IL18↓, 1,   IL1β↓, 18,   IL2↓, 2,   IL2↑, 1,   IL22↓, 1,   IL4↓, 2,   IL4↑, 3,   IL5↓, 1,   IL6↓, 19,   IL6↑, 1,   IL8↓, 8,   Inflam↓, 77,   Inflam↑, 1,   JAK↓, 2,   JAK2↓, 1,   JAK2↑, 1,   MCP1/CCL2↓, 2,   MCP1/CCL2↑, 1,   NF-kB↓, 31,   NF-kB↑, 1,   PGE2↓, 8,   RANTES↓, 1,   TLR1↓, 1,   TLR4↓, 1,   TNF-α↓, 36,   TNF-α↑, 1,   VitD↑, 2,  

Cellular Microenvironment(tgid=17) ⓘ

NOX↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 6,   AChE↓, 6,   BDNF↑, 65,   BDNF↝, 1,   BDNF∅, 5,   ChAT↑, 2,   MAOA↝, 1,   PSD95↑, 5,   tau↓, 1,   p‑tau↓, 3,   TrkB↓, 1,   TrkB↑, 10,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 6,   BACE/β-secretase↓, 3,   NLRP3↓, 5,   NLRP3↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

cortisol↑, 1,   DHT↑, 1,   SHBG↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv?, 1,   BioAv↓, 14,   BioAv↑, 31,   BioAv↝, 12,   BioEnh↑, 3,   Dose?, 1,   Dose↓, 1,   Dose↝, 16,   Dose∅, 2,   eff↓, 2,   eff↑, 28,   eff↝, 2,   Half-Life?, 1,   Half-Life↓, 4,   Half-Life↑, 6,   Half-Life↝, 1,   Half-Life∅, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 8,   ALAT↑, 1,   ALP↓, 3,   ascitic↓, 1,   AST↓, 6,   AST↑, 1,   BG↓, 1,   Bil↓, 1,   BMD↑, 5,   BMPs↓, 1,   BMPs↑, 1,   BP↓, 2,   CEA↓, 1,   creat↓, 7,   CRP↓, 1,   EGFR↓, 1,   GutMicro↑, 6,   GutMicro↝, 2,   hs-CRP↓, 1,   IL6↓, 19,   IL6↑, 1,   LDH↓, 3,   VitD↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↑, 5,   cardioP↑, 17,   chemoP↑, 3,   cognitive↑, 30,   cognitive∅, 1,   GFR↑, 1,   hepatoP↓, 2,   hepatoP↑, 21,   memory↑, 30,   Mood↑, 15,   motorD↑, 5,   neuroP↑, 35,   OS↑, 1,   radioP↑, 4,   RenoP↓, 1,   RenoP↑, 11,   Risk↓, 3,   Risk↝, 1,   Sleep↑, 1,   Strength↑, 1,   toxicity↓, 30,   toxicity↝, 4,   toxicity∅, 8,   Weight↓, 1,   Wound Healing↑, 4,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   Bacteria↓, 12,   Sepsis↓, 2,  
Total Targets: 399

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:0  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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