| Source: |
| Type: type of cell death |
| Situation in which a cell actively pursues a course toward death upon receiving certain stimuli. Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die. |
| 6461- | 1,8-Cin, | 1,8-cineole (eucalyptol): A versatile phytochemical with therapeutic applications across multiple diseases |
| - | Review, | AD, | NA | - | Review, | Var, | NA |
| 6476- | 1,8-Cin, | Specific induction of apoptosis by 1,8-cineole in two human leukemia cell lines, but not a in human stomach cancer cell line |
| - | in-vitro, | AML, | NA |
| 6467- | 1,8-Cin, | Evaluation of in vitro anticancer activity of 1,8-Cineole-containing n-hexane extract of Callistemon citrinus (Curtis) Skeels plant and its apoptotic potential |
| - | in-vitro, | Melanoma, | A431 | - | in-vitro, | OS, | MG63 | - | in-vitro, | Nor, | HaCaT |
| 6463- | 1,8-Cin, | Antitumor effect of 1, 8-cineole against colon cancer |
| - | vitro+vivo, | Colon, | HCT116 |
| 2327- | 2DG, | 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents |
| - | Review, | Var, | NA |
| 2432- | 2DG, | Inhibition of glycolytic enzyme hexokinase II (HK2) suppresses lung tumor growth |
| - | in-vitro, | Lung, | H23 | - | in-vitro, | Lung, | KP2 | - | in-vivo, | NA, | NA |
| 5263- | 3BP, | CET, | 3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis |
| - | in-vitro, | CRC, | DLD1 | - | NA, | NA, | HCT116 |
| 5269- | 3BP, | The anti-metabolite KAT/3BP has in vitro and in vivo anti-tumor activity in lymphoma models. |
| - | in-vitro, | HCC, | NA |
| 5265- | 3BP, | KAT/3BP: A Metabolism-Targeting Agent with Single and Combination Activity in Aggressive B-Cell Lymphomas |
| - | Review, | lymphoma, | NA |
| 5266- | 3BP, | 3-bromopyruvate-based agent KAT-101 |
| - | Review, | Var, | NA |
| 5270- | 5-ALA, | PDT, | 5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy |
| - | Review, | Var, | NA |
| 3453- | 5-ALA, | The heme precursor 5-aminolevulinic acid disrupts the Warburg effect in tumor cells and induces caspase-dependent apoptosis |
| - | in-vitro, | Lung, | A549 |
| - | in-vitro, | CRC, | NA |
| 5459- | AF, | Auranofin Induces Lethality Driven by Reactive Oxygen Species in High-Grade Serous Ovarian Cancer Cells |
| - | in-vitro, | Ovarian, | NA |
| 5463- | AF, | Will Auranofin Become a Golden New Treatment Against COVID-19? |
| - | Review, | Covid, | NA |
| 5462- | AF, | Repurposing Auranofin for Oncology and Beyond: A Brief Overview of Clinical Trials as Mono- and Combination Therapy |
| - | Review, | Var, | NA |
| 5460- | AF, | Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species |
| - | vitro+vivo, | Var, | 4T1 |
| 5472- | AF, | Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion |
| - | in-vitro, | Cerv, | HeLa |
| 5468- | AF, | The gold complex auranofin: new perspectives for cancer therapy |
| - | Review, | Var, | NA |
| 5431- | AG, | Advances in research on the anti-tumor mechanism of Astragalus polysaccharides |
| - | Review, | Var, | NA |
| 5434- | AG, | Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview |
| - | Review, | Liver, | NA |
| 1334- | AG, | Astragalus membranaceus: A Review of Its Antitumor Effects on Non-Small Cell Lung Cancer |
| - | Review, | NA, | NA |
| 1338- | AG, | The Modulatory Properties of Astragalus membranaceus Treatment on Triple-Negative Breast Cancer: An Integrated Pharmacological Method |
| - | in-vitro, | BC, | NA |
| 1295- | AG, | Cisplatin, | Chemosensitizing Effect of Astragalus Polysaccharides on Nasopharyngeal Carcinoma Cells by Inducing Apoptosis and Modulating Expression of Bax/Bcl-2 Ratio and Caspases |
| - | in-vivo, | Laryn, | NA |
| 1000- | AG, | 5-FU, | Characterization and anti-tumor bioactivity of astragalus polysaccharides by immunomodulation |
| - | vitro+vivo, | BC, | 4T1 |
| 328- | AgNPs, | Rad, | Silver nanoparticles outperform gold nanoparticles in radiosensitizing U251 cells in vitro and in an intracranial mouse model of glioma |
| - | vitro+vivo, | GBM, | U251 |
| 342- | AgNPs, | Silver nanoparticles; a new hope in cancer therapy? |
| - | Review, | NA, | NA |
| 338- | AgNPs, | Biogenic silver nanoparticles: In vitro and in vivo antitumor activity in bladder cancer |
| - | vitro+vivo, | Bladder, | 5637 |
| 336- | AgNPs, | PDT, | Photodynamic ability of silver nanoparticles in inducing cytotoxic effects in breast and lung cancer cell lines |
| - | in-vitro, | BC, | MCF7 |
| 329- | AgNPs, | Rad, | Enhancement of radiotherapy efficacy by silver nanoparticles in hypoxic glioma cells |
| - | in-vitro, | GBM, | U251 |
| 327- | AgNPs, | MS-275, | Combination Effect of Silver Nanoparticles and Histone Deacetylases Inhibitor in Human Alveolar Basal Epithelial Cells |
| - | in-vitro, | Lung, | A549 |
| 326- | AgNPs, | TSA, | Modulating chromatin structure and DNA accessibility by deacetylase inhibition enhances the anti-cancer activity of silver nanoparticles |
| - | in-vitro, | Cerv, | HeLa |
| 325- | AgNPs, | Silver nanoparticles modulate ABC transporter activity and enhance chemotherapy in multidrug resistant cancer |
| 319- | AgNPs, | Endoplasmic reticulum stress signaling is involved in silver nanoparticles-induced apoptosis |
| 306- | AgNPs, | Cancer Therapy by Silver Nanoparticles: Fiction or Reality? |
| - | Analysis, | NA, | NA |
| 374- | AgNPs, | Silver nanoparticles selectively treat triple‐negative breast cancer cells without affecting non‐malignant breast epithelial cells in vitro and in vivo |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vivo, | NA, | NA |
| 369- | AgNPs, | Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis |
| - | in-vitro, | Liver, | NA |
| 363- | AgNPs, | Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis |
| 361- | AgNPs, | Annona muricata assisted biogenic synthesis of silver nanoparticles regulates cell cycle arrest in NSCLC cell lines |
| - | in-vitro, | Lung, | A549 |
| 347- | AgNPs, | The Role of Silver Nanoparticles in the Diagnosis and Treatment of Cancer: Are There Any Perspectives for the Future? |
| - | Review, | NA, | NA |
| - | in-vitro, | BC, | MCF7 |
| 349- | AgNPs, | Insight into the molecular mechanism, cytotoxic, and anticancer activities of phyto-reduced silver nanoparticles in MCF-7 breast cancer cell lines |
| - | in-vitro, | BC, | MCF7 |
| 355- | AgNPs, | Cytotoxicity and Genotoxicity of Biogenic Silver Nanoparticles in A549 and BEAS-2B Cell Lines |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | NA, | BEAS-2B |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | Bladder, | HTB-22 |
| 353- | AgNPs, | The mechanism of cell death induced by silver nanoparticles is distinct from silver cations |
| - | in-vitro, | BC, | SUM159 |
| 377- | AgNPs, | Anticancer Action of Silver Nanoparticles in SKBR3 Breast Cancer Cells through Promotion of Oxidative Stress and Apoptosis |
| - | in-vitro, | BC, | SkBr3 |
| 376- | AgNPs, | Antitumor activity of colloidal silver on MCF-7 human breast cancer cells |
| - | in-vitro, | BC, | MCF7 |
| 400- | AgNPs, | MF, | Polyvinyl Alcohol Capped Silver Nanostructures for Fortified Apoptotic Potential Against Human Laryngeal Carcinoma Cells Hep-2 Using Extremely-Low Frequency Electromagnetic Field |
| - | in-vitro, | Laryn, | HEp2 |
| 381- | AgNPs, | Silver Nanoparticles Exert Apoptotic Activity in Bladder Cancer 5637 Cells Through Alteration of Bax/Bcl-2 Genes Expression |
| - | in-vitro, | Bladder, | 5637 |
| 382- | AgNPs, | Investigation the apoptotic effect of silver nanoparticles (Ag-NPs) on MDA-MB 231 breast cancer epithelial cells via signaling pathways |
| - | in-vitro, | BC, | MDA-MB-231 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:14 State#:% Dir#:2
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