Apoptosis Cancer Research Results

Apoptosis, Apoptosis: Click to Expand ⟱
Source:
Type: type of cell death
Situation in which a cell actively pursues a course toward death upon receiving certain stimuli.
Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die.


Scientific Papers found: Click to Expand⟱
6461- 1,8-Cin,    1,8-cineole (eucalyptol): A versatile phytochemical with therapeutic applications across multiple diseases
- Review, AD, NA - Review, Var, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *Half-Life↝, *toxicity↓, *PGE2↓, *TNF-α↓, *IL1β↓, *NO↓, *NF-kB↓, *PPARγ↓, COX2↓, *ROS↓, *SOD↑, *Catalase↑, *TAC↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *NADPH↑, *GPx↑, *AntiBio↑, *eff↑, *AntiFungal↑, *AntiViral↑, *TRPA1↑, eff↑, TumCCA↑, ROS↑, MAPK↝, mTOR↝, Apoptosis↑, survivin↓, Akt↓, p38↑, cl‑PARP↑, cl‑Casp3⇅, P53↑, BAX↑, Cyt‑c↑, Casp9↑, Dose↝, *Aβ↓, *tau↓, *GSK‐3β↓, *BACE↓, *cardioP↑, MFN2↑,
6476- 1,8-Cin,    Specific induction of apoptosis by 1,8-cineole in two human leukemia cell lines, but not a in human stomach cancer cell line
- in-vitro, AML, NA
TumCG↓, selectivity↑, Apoptosis↑,
6467- 1,8-Cin,    Evaluation of in vitro anticancer activity of 1,8-Cineole-containing n-hexane extract of Callistemon citrinus (Curtis) Skeels plant and its apoptotic potential
- in-vitro, Melanoma, A431 - in-vitro, OS, MG63 - in-vitro, Nor, HaCaT
TumCP↓, selectivity↑, AntiCan↑, TumCD↑, Apoptosis↑, Dose↝, ROS↑,
6463- 1,8-Cin,    Antitumor effect of 1, 8-cineole against colon cancer
- vitro+vivo, Colon, HCT116
TumCP↓, Apoptosis↑, survivin↓, Akt↓, p38↑, cl‑PARP↑, cl‑Casp3↑, TumVol↓,
2327- 2DG,    2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents
- Review, Var, NA
Glycolysis↓, HK2↓, mt-ROS↑, AMPK↑, PPP↓, NADPH↓, GSH↓, Bax:Bcl2↑, Apoptosis↑, RadioS↑, eff↓, Half-Life↓, other↝, eff↓,
2432- 2DG,    Inhibition of glycolytic enzyme hexokinase II (HK2) suppresses lung tumor growth
- in-vitro, Lung, H23 - in-vitro, Lung, KP2 - in-vivo, NA, NA
HK2↓, Apoptosis↑, TumAuto↑, TumCG↓,
5263- 3BP,  CET,    3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis
- in-vitro, CRC, DLD1 - NA, NA, HCT116
eff↑, Ferroptosis↓, TumAuto↑, Apoptosis↑, FOXO3↑, AMPKα↑, p‑Beclin-1↑, HK2↓, ATP↓, ROS↑, Dose↝, TumVol↓, TumW↓, xCT↑, GSH↓, eff↓, MDA↑,
5269- 3BP,    The anti-metabolite KAT/3BP has in vitro and in vivo anti-tumor activity in lymphoma models.
- in-vitro, HCC, NA
toxicity↑, eff↝, eff↑, Glycolysis↓, HK2↓, AIF↑, Apoptosis↑, NK cell↑, toxicity↑, toxicity↓, Dose↝, AntiTum↑,
5265- 3BP,    KAT/3BP: A Metabolism-Targeting Agent with Single and Combination Activity in Aggressive B-Cell Lymphomas
- Review, lymphoma, NA
Glycolysis↓, HK2↓, AIF↓, Apoptosis↑, NK cell↑,
5266- 3BP,    3-bromopyruvate-based agent KAT-101
- Review, Var, NA
eff↑, Glycolysis↓, OXPHOS↓, ATP↓, TumCP↓, Apoptosis↑, HK2↓, MPT↑, LDH↓, PDH↓,
5270- 5-ALA,  PDT,    5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy
- Review, Var, NA
other↝, ROS↑, other↝, mtDam↑, Ca+2↑, ER Stress↑, Apoptosis↑, TumAuto↑, other↝, Dose↝, Imm↑,
3453- 5-ALA,    The heme precursor 5-aminolevulinic acid disrupts the Warburg effect in tumor cells and induces caspase-dependent apoptosis
- in-vitro, Lung, A549
OXPHOS↑, OCR↑, Warburg↓, ROS↑, SOD2↑, Catalase↑, HO-1↑, Casp3↑, Apoptosis↑,
4774- 5-FU,  TQ,  CoQ10,    Exploring potential additive effects of 5-fluorouracil, thymoquinone, and coenzyme Q10 triple therapy on colon cancer cells in relation to glycolysis and redox status modulation
- in-vitro, CRC, NA
AntiCan↑, TumCCA↑, Apoptosis↑, eff↑, Bcl-2↓, survivin↓, P21↑, p27↑, BAX↑, Cyt‑c↑, Casp3↑, PI3K↓, Akt↓, mTOR↓, Hif1a↓, PTEN↑, AMPKα↑, PDH↑, LDHA↓, antiOx↓, ROS↑, AntiCan↑,
5459- AF,    Auranofin Induces Lethality Driven by Reactive Oxygen Species in High-Grade Serous Ovarian Cancer Cells
- in-vitro, Ovarian, NA
ROS↑, TrxR↓, MMP↓, Apoptosis↑, eff↓, Casp3↑, Casp7↑, DNAdam↑, eff↑, GSH↓, angioG↓, ChemoSen↑, cl‑PARP↑, eff↑,
5463- AF,    Will Auranofin Become a Golden New Treatment Against COVID-19?
- Review, Covid, NA
IL6↓, NF-kB↓, ATF2↓, TrxR↓, ROS↑, Apoptosis↑, IL6↓, Dose↑,
5462- AF,    Repurposing Auranofin for Oncology and Beyond: A Brief Overview of Clinical Trials as Mono- and Combination Therapy
- Review, Var, NA
AntiTum↑, Bacteria↓, TrxR↓, ChemoSen↑, Dose↝, ROS↑, Apoptosis↑, mTOR↓,
5460- AF,    Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species
- vitro+vivo, Var, 4T1
RadioS↑, ROS↑, eff↓, mt-OCR↓, DNAdam↑, Apoptosis↑, TrxR↓, eff↑,
5472- AF,    Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion
- in-vitro, Cerv, HeLa
TrxR↓, AntiCan↑, TumCG↓, Apoptosis↑, necrosis↑, cl‑PARP↑, MMP↓, ROS↑, GSH↓, eff↓,
5468- AF,    The gold complex auranofin: new perspectives for cancer therapy
- Review, Var, NA
TrxR↓, ROS↑, eff↑, Apoptosis↑, TumCG↓, TumCP↓, Akt↓, NF-kB↓, DNAdam↑, eff↝, eff↓, PI3K↓, Akt↓, mTOR↓, Hif1a↓, VEGF↓, Casp3↑, CSCs↓, ATP↓, Glycolysis↓, eff↑, eff↑, MMP↓, AIF↑, toxicity↓,
5431- AG,    Advances in research on the anti-tumor mechanism of Astragalus polysaccharides
- Review, Var, NA
AntiTum↑, TumCG↓, TumCI↓, Apoptosis↑, Imm↑, Bcl-2↓, BAX↑, Wnt↓, β-catenin/ZEB1↓, TumCG↓, miR-133a-3p↑, JNK↓, Fas↑, P53↑, P21↑, NOTCH1↓, NOTCH3↓, TumCP↓, TumCCA↑, GPx4↓, xCT↓, AMPK↑, Beclin-1↑, NF-kB↓, EMT↓, Vim↓, TumMeta↓, VEGF↓, EGFR↓, eff↑, eff↑, MMP↓, P-gp↓, MMP9↓, ChemoSen↑, SIRT1↓, SREBP1↓, TumAuto↑, PI3K↓, mTOR↓, Casp3↑, Casp9↑, CD133↓, CD44↓, CSCs↓, QoL↑,
5434- AG,    Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview
- Review, Liver, NA
AntiCan↑, Apoptosis↑, TumCP↓, EMT↓, Imm↑, ChemoSen↑, BioAv↓, TumCG↓, IL2↑, IL12↑, TNF-α↑, P-gp↓, MDR1↓, QoL↑, Casp↑, DNAdam↑, Bcl-2↓, BAX↑, MMP↓, Cyt‑c↑, NOTCH1↓, GSK‐3β↓, TumCCA↑, GSH↓, ROS↑, lipid-P↑, c-Iron↑, GPx4↓, ACSL4↑, Ferroptosis↑, Wnt↓, β-catenin/ZEB1↓, cycD1/CCND1↓, Akt↓, PI3K↓, mTOR↓, CXCR4↓, Vim↓, PD-L1↓, eff↑, eff↑, ChemoSen↑, ChemoSen↑, chemoP↑,
1334- AG,    Astragalus membranaceus: A Review of Its Antitumor Effects on Non-Small Cell Lung Cancer
- Review, NA, NA
TumCP↓, Apoptosis↑, NF-kB↓, p50↓, cycD1/CCND1↓, Bcl-xL↓, ChemoSen↑, angioG↓, ChemoSen↑,
1338- AG,    The Modulatory Properties of Astragalus membranaceus Treatment on Triple-Negative Breast Cancer: An Integrated Pharmacological Method
- in-vitro, BC, NA
TumCI↓, Apoptosis↑, Symptoms↓, PIK3CA↓, Akt↓, Bcl-2↓,
1295- AG,  Cisplatin,    Chemosensitizing Effect of Astragalus Polysaccharides on Nasopharyngeal Carcinoma Cells by Inducing Apoptosis and Modulating Expression of Bax/Bcl-2 Ratio and Caspases
- in-vivo, Laryn, NA
AntiTum↑, Apoptosis↑, Bcl-2↓, BAX↑, Casp3↑, Casp9↑, Bax:Bcl2↑,
1000- AG,  5-FU,    Characterization and anti-tumor bioactivity of astragalus polysaccharides by immunomodulation
- vitro+vivo, BC, 4T1
TumCG↓, TumCCA↑, Apoptosis↑, *IL2↑, *TNF-α↑, *IFN-γ↑,
328- AgNPs,  Rad,    Silver nanoparticles outperform gold nanoparticles in radiosensitizing U251 cells in vitro and in an intracranial mouse model of glioma
- vitro+vivo, GBM, U251
Apoptosis↑, TumAuto↑,
342- AgNPs,    Silver nanoparticles; a new hope in cancer therapy?
- Review, NA, NA
ROS↑, DNAdam↑, Apoptosis↑, mtDam↑,
338- AgNPs,    Biogenic silver nanoparticles: In vitro and in vivo antitumor activity in bladder cancer
- vitro+vivo, Bladder, 5637
TumCD↑, Apoptosis↑, TumCMig↓, TumCP↓,
336- AgNPs,  PDT,    Photodynamic ability of silver nanoparticles in inducing cytotoxic effects in breast and lung cancer cell lines
- in-vitro, BC, MCF7
Apoptosis↑,
329- AgNPs,  Rad,    Enhancement of radiotherapy efficacy by silver nanoparticles in hypoxic glioma cells
- in-vitro, GBM, U251
Apoptosis↑, TumAuto↑,
327- AgNPs,  MS-275,    Combination Effect of Silver Nanoparticles and Histone Deacetylases Inhibitor in Human Alveolar Basal Epithelial Cells
- in-vitro, Lung, A549
Apoptosis↑, ROS↑, LDH↓, TNF-α↑, mtDam↑, TumAuto↑, Casp3↑, Casp9↑, DNAdam↑,
326- AgNPs,  TSA,    Modulating chromatin structure and DNA accessibility by deacetylase inhibition enhances the anti-cancer activity of silver nanoparticles
- in-vitro, Cerv, HeLa
Apoptosis↑, ChrMod↝, eff↑,
325- AgNPs,    Silver nanoparticles modulate ABC transporter activity and enhance chemotherapy in multidrug resistant cancer
Apoptosis↑, ABC↓,
319- AgNPs,    Endoplasmic reticulum stress signaling is involved in silver nanoparticles-induced apoptosis
Apoptosis↑, Ca+2↑, ER Stress↑, PERK↑, IRE1↑, cl‑ATF6↑,
306- AgNPs,    Cancer Therapy by Silver Nanoparticles: Fiction or Reality?
- Analysis, NA, NA
EPR↝, ROS↑, IL1↑, IL8↑, ER Stress↑, MMP9↑, MMP↓, Cyt‑c↑, Apoptosis↑, Hif1a↑, BBB↑, GutMicro↝, eff↑, eff↑, RadioS↑,
374- AgNPs,    Silver nanoparticles selectively treat triple‐negative breast cancer cells without affecting non‐malignant breast epithelial cells in vitro and in vivo
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
ER Stress↑, DNAdam↑, ROS↑, Apoptosis↑, GSH/GSSG↓, NADPH/NADP+↓, TumCG↓, UPR↑,
369- AgNPs,    Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis
- in-vitro, Liver, NA
ROS↑, GSH↓, DNAdam↑, lipid-P↝, Apoptosis↑, BAX↑, Bcl-2↓, MMP↓, Casp9↑, Casp3↑, JNK↑,
363- AgNPs,    Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis
ROS↑, lipid-P↑, Apoptosis↑, BAX↑, Bcl-2↓, MMP↓, Cyt‑c↑, Casp3↑, Casp9↑, JNK↑,
361- AgNPs,    Annona muricata assisted biogenic synthesis of silver nanoparticles regulates cell cycle arrest in NSCLC cell lines
- in-vitro, Lung, A549
Apoptosis↑, Casp↑, TumCCA↑,
347- AgNPs,    The Role of Silver Nanoparticles in the Diagnosis and Treatment of Cancer: Are There Any Perspectives for the Future?
- Review, NA, NA
ROS↑, Apoptosis↑, ER Stress↑,
348- AgNPs,    Induction of p53 mediated mitochondrial apoptosis and cell cycle arrest in human breast cancer cells by plant mediated synthesis of silver nanoparticles from Bergenia ligulata (Whole plant)
- in-vitro, BC, MCF7
Apoptosis↑, ROS↑, MMP↓, P53↑, BAX↑, cl‑Casp3↑,
349- AgNPs,    Insight into the molecular mechanism, cytotoxic, and anticancer activities of phyto-reduced silver nanoparticles in MCF-7 breast cancer cell lines
- in-vitro, BC, MCF7
Apoptosis↑, ROS↑, CellMemb↑,
355- AgNPs,    Cytotoxicity and Genotoxicity of Biogenic Silver Nanoparticles in A549 and BEAS-2B Cell Lines
- in-vitro, Lung, A549 - in-vitro, NA, BEAS-2B
ROS↑, DNAdam↑, Apoptosis↑,
356- AgNPs,  MF,    Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study
- in-vitro, BC, MCF7 - in-vitro, Bladder, HTB-22
Apoptosis↑, P53↑, iNOS↑, NF-kB↑, Bcl-2↓, ROS↑, SOD↑, TumCCA↑, eff↑, Catalase↑, other↑,
353- AgNPs,    The mechanism of cell death induced by silver nanoparticles is distinct from silver cations
- in-vitro, BC, SUM159
lipid-P↑, H2O2↑, ROS↑, Apoptosis↑,
377- AgNPs,    Anticancer Action of Silver Nanoparticles in SKBR3 Breast Cancer Cells through Promotion of Oxidative Stress and Apoptosis
- in-vitro, BC, SkBr3
ROS↑, Apoptosis↑, Bax:Bcl2↑, VEGF↑, Akt↓, PI3K↓, TAC↓, TOS↑, OSI↑, MDA↑, Casp3↑, Casp7↑,
376- AgNPs,    Antitumor activity of colloidal silver on MCF-7 human breast cancer cells
- in-vitro, BC, MCF7
Apoptosis↑, LDH↓, SOD↑, DNAdam↑,
400- AgNPs,  MF,    Polyvinyl Alcohol Capped Silver Nanostructures for Fortified Apoptotic Potential Against Human Laryngeal Carcinoma Cells Hep-2 Using Extremely-Low Frequency Electromagnetic Field
- in-vitro, Laryn, HEp2
TumCP↓, Casp3↑, P53↑, Beclin-1↑, TumAuto↑, GSR↑, ROS↑, MDA↑, ROS↑, SIRT1↑, Ca+2↑, Endon↑, DNAdam↑, Apoptosis↑, NF-kB↓,
381- AgNPs,    Silver Nanoparticles Exert Apoptotic Activity in Bladder Cancer 5637 Cells Through Alteration of Bax/Bcl-2 Genes Expression
- in-vitro, Bladder, 5637
ROS↑, BAX↑, Bcl-2↓, Casp3↑, Casp7↑, Apoptosis↑,
382- AgNPs,    Investigation the apoptotic effect of silver nanoparticles (Ag-NPs) on MDA-MB 231 breast cancer epithelial cells via signaling pathways
- in-vitro, BC, MDA-MB-231
Apoptosis↑, BAX↑, Bcl-2↓, P53↑, PTEN↑, hTERT/TERT↓, p‑ERK↓, cycD1/CCND1↓,

Showing Research Papers: 1 to 50 of 1281
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1281

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

antiOx↓, 1,   Catalase↑, 2,   Ferroptosis↓, 1,   Ferroptosis↑, 1,   GPx4↓, 2,   GSH↓, 6,   GSH/GSSG↓, 1,   GSR↑, 1,   H2O2↑, 1,   HO-1↑, 1,   c-Iron↑, 1,   lipid-P↑, 3,   lipid-P↝, 1,   MDA↑, 3,   MFN2↑, 1,   NADPH/NADP+↓, 1,   OSI↑, 1,   OXPHOS↓, 1,   OXPHOS↑, 1,   ROS↑, 29,   mt-ROS↑, 1,   SOD↑, 2,   SOD2↑, 1,   TAC↓, 1,   TOS↑, 1,   TrxR↓, 6,   xCT↓, 1,   xCT↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

AIF↓, 1,   AIF↑, 2,   ATP↓, 3,   MMP↓, 9,   MPT↑, 1,   mtDam↑, 3,   OCR↑, 1,   mt-OCR↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

ACSL4↑, 1,   AMPK↑, 2,   Glycolysis↓, 5,   HK2↓, 6,   LDH↓, 3,   LDHA↓, 1,   NADPH↓, 1,   PDH↓, 1,   PDH↑, 1,   PIK3CA↓, 1,   PPP↓, 1,   SIRT1↓, 1,   SIRT1↑, 1,   SREBP1↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5)

Akt↓, 8,   Apoptosis↑, 50,   ATF2↓, 1,   BAX↑, 10,   Bax:Bcl2↑, 3,   Bcl-2↓, 10,   Bcl-xL↓, 1,   Casp↑, 2,   Casp3↑, 12,   cl‑Casp3↑, 2,   cl‑Casp3⇅, 1,   Casp7↑, 3,   Casp9↑, 6,   Cyt‑c↑, 5,   Endon↑, 1,   Fas↑, 1,   Ferroptosis↓, 1,   Ferroptosis↑, 1,   hTERT/TERT↓, 1,   iNOS↑, 1,   JNK↓, 1,   JNK↑, 2,   MAPK↝, 1,   necrosis↑, 1,   p27↑, 1,   p38↑, 2,   survivin↓, 3,   TumCD↑, 2,  

Kinase & Signal Transduction(tgid=6)

AMPKα↑, 2,  

Transcription & Epigenetics(tgid=7)

ChrMod↝, 1,   other↑, 1,   other↝, 4,  

Protein Folding & ER Stress(tgid=8)

cl‑ATF6↑, 1,   ER Stress↑, 5,   IRE1↑, 1,   PERK↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9)

Beclin-1↑, 2,   p‑Beclin-1↑, 1,   TumAuto↑, 8,  

DNA Damage & Repair(tgid=10)

DNAdam↑, 11,   P53↑, 6,   cl‑PARP↑, 4,  

Cell Cycle & Senescence(tgid=11)

cycD1/CCND1↓, 3,   P21↑, 2,   TumCCA↑, 7,  

Proliferation, Differentiation & Cell State(tgid=12)

CD133↓, 1,   CD44↓, 1,   CSCs↓, 2,   EMT↓, 2,   p‑ERK↓, 1,   FOXO3↑, 1,   GSK‐3β↓, 1,   mTOR↓, 5,   mTOR↝, 1,   NOTCH1↓, 2,   NOTCH3↓, 1,   PI3K↓, 5,   PTEN↑, 2,   TumCG↓, 9,   Wnt↓, 2,  

Migration(tgid=13)

Ca+2↑, 3,   miR-133a-3p↑, 1,   MMP9↓, 1,   MMP9↑, 1,   TumCI↓, 2,   TumCMig↓, 1,   TumCP↓, 9,   TumMeta↓, 1,   Vim↓, 2,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 2,   EGFR↓, 1,   EPR↝, 1,   Hif1a↓, 2,   Hif1a↑, 1,   VEGF↓, 2,   VEGF↑, 1,  

Barriers & Transport(tgid=15)

BBB↑, 1,   CellMemb↑, 1,   P-gp↓, 2,  

Immune & Inflammatory Signaling(tgid=16)

COX2↓, 1,   CXCR4↓, 1,   IL1↑, 1,   IL12↑, 1,   IL2↑, 1,   IL6↓, 2,   IL8↑, 1,   Imm↑, 3,   NF-kB↓, 5,   NF-kB↑, 1,   NK cell↑, 2,   p50↓, 1,   PD-L1↓, 1,   TNF-α↑, 2,  

Drug Metabolism & Resistance(tgid=21)

ABC↓, 1,   BioAv↓, 1,   ChemoSen↑, 8,   Dose↑, 1,   Dose↝, 6,   eff↓, 7,   eff↑, 19,   eff↝, 2,   Half-Life↓, 1,   MDR1↓, 1,   RadioS↑, 3,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22)

EGFR↓, 1,   GutMicro↝, 1,   hTERT/TERT↓, 1,   IL6↓, 2,   LDH↓, 3,   PD-L1↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 5,   AntiTum↑, 4,   chemoP↑, 1,   QoL↑, 2,   Symptoms↓, 1,   toxicity↓, 2,   toxicity↑, 2,   TumVol↓, 2,   TumW↓, 1,  

Infection & Microbiome(tgid=24)

Bacteria↓, 1,  
Total Targets: 174

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

AntiBio↑, 1,   TRPA1↑, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 1,   Catalase↑, 1,   GPx↑, 1,   HO-1↑, 1,   lipid-P↓, 1,   MDA↓, 1,   NRF2↑, 1,   ROS↓, 1,   SOD↑, 1,   TAC↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

NADPH↑, 1,   PPARγ↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

GSK‐3β↓, 1,  

Angiogenesis & Vasculature(tgid=14)

NO↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

IFN-γ↑, 1,   IL1β↓, 1,   IL2↑, 1,   Inflam↓, 1,   NF-kB↓, 1,   PGE2↓, 1,   TNF-α↓, 1,   TNF-α↑, 1,  

Synaptic & Neurotransmission(tgid=18)

tau↓, 1,  

Protein Aggregation(tgid=19)

Aβ↓, 1,   BACE↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 1,   eff↑, 1,   Half-Life↝, 1,  

Functional Outcomes(tgid=23)

cardioP↑, 1,   neuroP↑, 1,   toxicity↓, 1,  

Infection & Microbiome(tgid=24)

AntiFungal↑, 1,   AntiViral↑, 1,  
Total Targets: 35

Scientific Paper Hit Count for: Apoptosis, Apoptosis
66 Silver-NanoParticles
66 Curcumin
37 Magnetic Fields
36 Quercetin
32 Sulforaphane (mainly Broccoli)
31 Berberine
30 Thymoquinone
27 Baicalein
26 EGCG (Epigallocatechin Gallate)
24 Capsaicin
22 Phenethyl isothiocyanate
22 Shikonin
21 Ashwagandha(Withaferin A)
20 Betulinic acid
19 Resveratrol
19 Selenite (Sodium)
18 Radiotherapy/Radiation
18 Artemisinin
18 Apigenin (mainly Parsley)
17 Boron
17 Garcinol
16 Chrysin
16 Honokiol
15 Dandelion Root
15 Eugenol
14 Chemotherapy
14 chitosan
14 Nimbolide
13 Magnolol
13 Lycopene
12 Cisplatin
12 Astaxanthin
12 Beta-Caryophyllene
12 salinomycin
12 Graviola
12 Luteolin
12 Urolithin
11 Carvacrol
11 Dichloroacetate
11 Gambogic Acid
10 Allicin (mainly Garlic)
10 Metformin
10 Crocetin
10 Piperlongumine
10 Selenium NanoParticles
9 Copper and Cu NanoParticles
9 Vitamin C (Ascorbic Acid)
9 Propolis -bee glue
9 Chlorogenic acid
9 Cucurbitacin
9 Silymarin (Milk Thistle) silibinin
9 Juglone
8 Photodynamic Therapy
8 5-fluorouracil
8 Alpha-Lipoic-Acid
8 Bufalin/Huachansu
8 Selenium
8 Citric Acid
8 Electrical Pulses
8 Fisetin
8 Magnetic Field Rotating
8 Phenylbutyrate
8 Rosmarinic acid
7 Auranofin
7 Gemcitabine (Gemzar)
7 Paclitaxel
7 Atorvastatin
7 Biochanin A
7 Boswellia (frankincense)
7 α-Bisabolol / Chamomile oil
7 Cinnamon
7 Carvone
7 Deguelin
7 Emodin
7 HydroxyTyrosol
7 Ursolic acid
6 Coenzyme Q10
6 Astragalus
6 Andrographis
6 borneol
6 Caffeic acid
6 Carnosic acid
6 Disulfiram
6 Ellagic acid
6 Echinacea
6 Piperine
6 Terpinen-4-ol / Tea Tree Oil
5 Anethole/trans-Anethole
5 immunotherapy
5 doxorubicin
5 Thymol-Thymus vulgaris
5 Celecoxib
5 Celastrol
5 Diclofenac
5 D-limonene
5 Aflavin-3,3′-digallate
5 Genistein (soy isoflavone)
5 Plumbagin
5 Pterostilbene
5 Vitamin K2
4 1,8-Cineole
4 3-bromopyruvate
4 Gold NanoParticles
4 Ascorbyl Palmitate
4 Melatonin
4 Berbamine
4 Brucea javanica
4 Bacopa monnieri
4 Bromelain
4 Butyrate
4 Centella asiatica / Gotu kola → asiaticoside
4 Chlorophyllin
4 Dichloroacetophenone(2,2-)
4 Ferulic acid
4 Linalool
4 Parthenolide
4 Spermidine
3 2-DeoxyGlucose
3 Aspirin
3 Dipyridamole
3 tamoxifen
3 Baicalin
3 brusatol
3 Bruteridin(bergamot juice)
3 Cat’s Claw
3 Cannabidiol
3 Date Fruit Extract
3 diet FMD Fasting Mimicking Diet
3 Eurycomanone
3 Ginkgo biloba
3 Geraniol
3 γ-linolenic acid (Borage Oil)
3 Hyperthermia
3 Methyl salicylate / Sweet Birch oil
3 Magnesium
3 Niclosamide (Niclocide)
3 Sanguinarine
3 Psoralidin
3 α-Santalol/Sandalwood oil
3 VitK3,menadione
3 Zerumbone
2 cetuximab
2 5-Aminolevulinic acid
2 Fenbendazole
2 Ajoene (compound of Garlic)
2 alpha Linolenic acid
2 DTS(dibenzyl trisulphide) from Anamu
2 Sorafenib (brand name Nexavar)
2 Aloe anthraquinones
2 beta-glucans
2 Docetaxel
2 Bortezomib
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Chocolate
2 irinotecan
2 CUSP9
2 Cyclopamine
2 gefitinib, erlotinib
2 Folic Acid, Vit B9
2 Fucoidan
2 Fennel Oil/Foeniculum vulgare
2 Shilajit/Fulvic Acid
2 Galloflavin
2 Methylglyoxal
2 Naringin
2 Oleuropein
2 Oleocanthal
2 Orlistat
2 Oxygen, Hyperbaric
2 Propyl gallate
2 Rutin
2 polyethylene glycol
2 Vitamin D3
1 entinostat
1 Trichostatin A
1 Glucose
1 temozolomide
1 Trastuzumab
1 almonertinib
1 epirubicin
1 Lapatinib
1 bempedoic acid
1 Bifidobacterium
1 Beta‐Lapachone
1 Selenate
1 Prebiotic
1 Hydroxycinnamic-acid
1 Vitamin E
1 Carica papaya leaf extract
1 Camptothecin
1 Dihydrocaffeic Acid
1 methylseleninic acid
1 diet Methionine-Restricted Diet
1 diet Short Term Fasting
1 Dimethyl Sulfoxide
1 Mistletoe
1 Lemongrass Extract/Citral
1 Cichoric acid / Chicoric acid
1 Cannabichromene
1 Evodiamine
1 Gallic acid
1 carboplatin
1 Ginger/6-Shogaol/Gingerol
1 Grapeseed extract
1 Hydrogen Gas
1 HydroxyCitric Acid
1 Rapamycin
1 Indole-3-carbinol
1 Inoscavin A
1 Ivermectin
1 Licorice
1 Iron
1 magnetic nanoparticles
1 Methylsulfonylmethane
1 Mushroom Chaga
1 Proanthocyanidins
1 isoflavones
1 Vorinostat
1 Oxaliplatin
1 Sulfasalazine
1 Scoulerine
1 acetazolamide
1 Osimertinib
1 Adagrasib
1 Glutathione
1 Tomatine
1 Turmerones
1 Whole Body Vibration
1 xanthohumol
1 Zinc Oxide
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:14  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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