| Source: HalifaxProj(inhibit) |
| Type: |
| NF-kB signaling Nuclear factor kappa B (NF-κB) is a transcription factor that plays a crucial role in regulating immune response, inflammation, cell proliferation, and survival. NF-κB is often found to be constitutively active in many types of cancer cells. This persistent activation can promote tumorigenesis by enhancing cell survival, proliferation, and metastasis. |
| 5147- | AgNPs, | Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells |
| - | in-vitro, | Lung, | A549 |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | Bladder, | HTB-22 |
| - | in-vitro, | BC, | MCF-7 |
| 5340- | Ajoene, | Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB |
| - | in-vitro, | AML, | NA |
| 252- | Ajoene, | Ajoene, a Compound of Garlic, Induces Apoptosis in Human Promyeloleukemic Cells, Accompanied by Generation of Reactive Oxygen Species and Activation of Nuclear Factor κB |
| - | in-vitro, | AML, | HL-60 |
| 5356- | AL, | Therapeutic role of allicin in gastrointestinal cancers: mechanisms and safety aspects |
| - | Review, | GC, | NA |
| 298- | ALA, | Rad, | Synergistic Tumoricidal Effects of Alpha-Lipoic Acid and Radiotherapy on Human Breast Cancer Cells via HMGB1 |
| - | in-vitro, | BC, | MDA-MB-231 |
| 1123- | aLinA, | Linoleic acid induces an EMT-like process in mammary epithelial cells MCF10A |
| - | in-vitro, | BC, | NA | - | in-vitro, | NA, | MCF10 |
| 3385- | ART/DHA, | Interaction of artemisinin protects the activity of antioxidant enzyme catalase: A biophysical study |
| - | Study, | NA, | NA |
| 874- | B-Gluc, | Potential promising anticancer applications of β-glucans: a review |
| - | Review, | NA, | NA |
| 5505- | Ba, | Baicalein inhibits the progression of thyroid cancer by suppressing the TPL2/MEK2/ERK2 pathway |
| - | in-vitro, | Thyroid, | NA |
| 5551- | BBM, | Berbamine Suppresses the Progression of Bladder Cancer by Modulating the ROS/NF-κB Axis |
| - | vitro+vivo, | Bladder, | NA |
| 5582- | BetA, | Targeting mitochondrial apoptosis by betulinic acid in human cancers |
| - | Review, | Var, | NA |
| 2722- | BetA, | Betulinic Acid for Cancer Treatment and Prevention |
| - | Review, | Var, | NA |
| 2728- | BetA, | Betulinic acid as new activator of NF-kappaB: molecular mechanisms and implications for cancer therapy |
| - | in-vitro, | Var, | NA |
| 2729- | BetA, | Betulinic acid in the treatment of tumour diseases: Application and research progress |
| - | Review, | Var, | NA |
| 2752- | BetA, | Betulinic acid: a natural product with anticancer activity |
| - | Review, | Var, | NA |
| 5650- | BNL, | Borneol Depresses P-Glycoprotein Function by a NF-κB Signaling Mediated Mechanism in a Blood Brain Barrier in Vitro Model |
| - | in-vivo, | Nor, | NA |
| 2772- | Bos, | Mechanistic role of boswellic acids in Alzheimer’s disease: Emphasis on anti-inflammatory properties |
| - | Review, | AD, | NA |
| 4263- | CA, | Neuroprotective Effects of Carnosic Acid: Insight into Its Mechanisms of Action |
| - | Review, | AD, | NA |
| 5959- | CEL, | Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-κB as a possible target |
| - | in-vitro, | Cerv, | HeLa |
| 5986- | Chit, | The natural product chitosan enhances the anti-tumor activity of natural killer cells by activating dendritic cells |
| - | Study, | Var, | NA |
| 2783- | CHr, | Apoptotic Effects of Chrysin in Human Cancer Cell Lines |
| - | Review, | Var, | NA |
| 1085- | DHA, | EPA, | DHA and EPA Down-regulate COX-2 Expression through Suppression of NF-kappaB Activity in LPS-treated Human Umbilical Vein Endothelial Cells |
| - | in-vitro, | Nor, | HUVECs |
| 5008- | DSF, | Cu, | Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis |
| - | in-vitro, | HCC, | NA |
| 3236- | EGCG, | Buty, | Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate |
| - | in-vitro, | Colon, | RKO | - | in-vitro, | Colon, | HCT116 | - | in-vitro, | Colon, | HT29 |
| 2857- | FIS, | A review on the chemotherapeutic potential of fisetin: In vitro evidences |
| - | Review, | Var, | NA |
| 2082- | HNK, | Revealing the role of honokiol in human glioma cells by RNA-seq analysis |
| - | in-vitro, | GBM, | U87MG | - | in-vitro, | GBM, | U251 |
| 2914- | LT, | Therapeutic Potential of Luteolin on Cancer |
| - | Review, | Var, | NA |
| 4785- | Lyco, | The Protective Anticancer Effect of Natural Lycopene Supercritical CO2 Watermelon Extracts in Adenocarcinoma Lung Cancer Cells |
| - | in-vitro, | Lung, | A549 |
| 1780- | MEL, | Utilizing Melatonin to Alleviate Side Effects of Chemotherapy: A Potentially Good Partner for Treating Cancer with Ageing |
| - | Review, | Var, | NA |
| 1170- | MushCha, | Chaga mushroom extract suppresses oral cancer cell growth via inhibition of energy metabolism |
| - | in-vitro, | Oral, | HSC4 |
| 1668- | PBG, | Propolis: A Detailed Insight of Its Anticancer Molecular Mechanisms |
| - | Review, | Var, | NA |
| 2950- | PL, | Overview of piperlongumine analogues and their therapeutic potential |
| - | Review, | Var, | NA |
| 2987- | RES, | Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor Flk-1 |
| - | in-vivo, | Nor, | NA |
| 3040- | SK, | Pharmacological Properties of Shikonin – A Review of Literature since 2002 |
| - | Review, | Var, | NA | - | Review, | IBD, | NA | - | Review, | Stroke, | NA |
| 2093- | TQ, | Regulation of NF-κB Expression by Thymoquinone; A Role in Regulating Pro-Inflammatory Cytokines and Programmed Cell Death in Hepatic Cancer Cells |
| - | in-vitro, | Liver, | HepG2 | - | in-vitro, | Nor, | NA |
| 3397- | TQ, | Thymoquinone: A Promising Therapeutic Agent for the Treatment of Colorectal Cancer |
| - | Review, | CRC, | NA |
| 3113- | VitC, | Vitamin C enhances NF-κB-driven epigenomic reprogramming and boosts the immunogenic properties of dendritic cells |
| - | in-vitro, | Nor, | NA |
| 1832- | VitK3, | VitC, | Vitamin K3 and vitamin C alone or in combination induced apoptosis in leukemia cells by a similar oxidative stress signalling mechanism |
| - | in-vitro, | AML, | K562 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:214 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid