eff Cancer Research Results

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Scientific Papers found: Click to Expand⟱
4384- ,    Silver nanoparticles: synthesis, properties, and therapeutic applications
- Review, Var, NA
AntiCan↑, RadioS↑, CellMemb↑, ROS↑, DNAdam↑, PhotoS↑, eff↑,
6461- 1,8-Cin,    1,8-cineole (eucalyptol): A versatile phytochemical with therapeutic applications across multiple diseases
- Review, AD, NA - Review, Var, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *Half-Life↝, *toxicity↓, *PGE2↓, *TNF-α↓, *IL1β↓, *NO↓, *NF-kB↓, *PPARγ↓, COX2↓, *ROS↓, *SOD↑, *Catalase↑, *TAC↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *NADPH↑, *GPx↑, *AntiBio↑, *eff↑, *AntiFungal↑, *AntiViral↑, *TRPA1↑, eff↑, TumCCA↑, ROS↑, MAPK↝, mTOR↝, Apoptosis↑, survivin↓, Akt↓, p38↑, cl‑PARP↑, cl‑Casp3⇅, P53↑, BAX↑, Cyt‑c↑, Casp9↑, Dose↝, *Aβ↓, *tau↓, *GSK‐3β↓, *BACE↓, *cardioP↑, MFN2↑,
6474- 1,8-Cin,    Molecular Docking Identifies 1,8-Cineole (Eucalyptol) as A Novel PPARγ Agonist That Alleviates Colon Inflammation
- in-vitro, Nor, HT29 - in-vivo, Nor, NA - in-vivo, IBD, NA
*Inflam↓, *NRF2↑, *antiOx↑, *PPARγ↑, eff↑,
6468- 1,8-Cin,    Inhibitory activity of 1,8-cineol (eucalyptol) on cytokine production in cultured human lymphocytes and monocytes
- in-vitro, Nor, NA
*TNF-α↓, *IL1β↓, *eff↑,
6462- 1,8-Cin,    Modes of Action of 1,8-Cineol in Infections and Inflammation
- Review, Var, NA - Review, AD, NA
*BioAv↑, *BBB↑, *AntiViral↑, *Bacteria↓, *AntiFungal↑, *Inflam↓, *BioAv↑, *MUC2↓, *MUC19↓, *NF-kB↓, *ICAM-1↓, *VCAM-1↓, DNAdam↑, *lipid-P↓, *PGE2↓, *IL4↓, *IL6↓, *IL1β↓, *IL6↓, eff↑, TGF-β↓, fascin↓, VEGF↓, MMP9↓, *MAPK↓, *ERK↓, JNK↓, Wnt↓, β-catenin/ZEB1↓, GSK‐3β↑, *neuroP↑, *GSK‐3β↓, *AGEs↓, *BBB↑, *NLRP3↓,
2325- 2DG,    Research Progress of Warburg Effect in Hepatocellular Carcinoma
- Review, Var, NA
HK2↓, Glycolysis↓, PKM2↓, LDHA↓, TumCD↑, ChemoSen↑, eff↑,
1340- 3BP,    Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study
- Review, NA, NA
Glycolysis↓, HK2↓, LDH↓, OXPHOS↓, angioG↓, H2O2↑, eff↑,
1341- 3BP,    The HK2 Dependent “Warburg Effect” and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate
- Review, NA, NA
Glycolysis↓, OXPHOS↓, *toxicity↓, ROS↑, GSH↓, eff↑,
5282- 3BP,  Rad,    3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
Glycolysis↓, RadioS↑, eff↑, GAPDH↓, PPP↑, GSH↓, ECAR↓,
5278- 3BP,    effect-of-3-bromopyruvate-on-human-colorectal">The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression
- in-vitro, CRC, HCT116 - in-vitro, CRC, Caco-2 - in-vitro, CRC, SW48
ATP↓, TumCD↑, selectivity↑, toxicity↓, OS↑, HK2?, Cyt‑c↑, eff↑, p‑Akt↑,
5274- 3BP,    ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1
- in-vitro, PC, NA
eff↑, TumCG↓, TumMeta↓, toxicity↝, Glycolysis↓, toxicity↓, Dose↝,
5272- 3BP,    The efficacy of the anticancer 3-bromopyruvate is potentiated by antimycin and menadione by unbalancing mitochondrial ROS production and disposal in U118 glioblastoma cells
- in-vitro, GBM, U87MG - in-vitro, Nor, HEK293
Glycolysis↓, ROS↑, GPx↓, eff↓, OXPHOS↓, HK2↓, ATP↓, ROS↑, ER Stress↑, BioAv↓, Cyt‑c↑, eff↑,
5263- 3BP,  CET,    3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis
- in-vitro, CRC, DLD1 - NA, NA, HCT116
eff↑, Ferroptosis↓, TumAuto↑, Apoptosis↑, FOXO3↑, AMPKα↑, p‑Beclin-1↑, HK2↓, ATP↓, ROS↑, Dose↝, TumVol↓, TumW↓, xCT↑, GSH↓, eff↓, MDA↑,
5259- 3BP,    Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP
- in-vivo, HCC, NA
ATP↓, TumCD↑, toxicity↓, eff↑, tumCV↓, Dose↝,
5260- 3BP,    Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer
- in-vivo, PC, NA
TumCG↓, toxicity↓, BioAv↝, GAPDH↓, toxicity↑, Dose↝, ATP↓, eff↑, TumCI↓, MMP9↓, toxicity↓,
5261- 3BP,    The cytotoxicity of 3-bromopyruvate in breast cancer cells depends on extracellular pH
- in-vitro, BC, NA
eff↑, eff↓,
5269- 3BP,    The anti-metabolite KAT/3BP has in vitro and in vivo anti-tumor activity in lymphoma models.
- in-vitro, HCC, NA
toxicity↑, eff↝, eff↑, Glycolysis↓, HK2↓, AIF↑, Apoptosis↑, NK cell↑, toxicity↑, toxicity↓, Dose↝, AntiTum↑,
5264- 3BP,    Candidate cancer drug suspected after death of three patients at an alternative medicine clinic
- Review, Var, NA
toxicity↑, Glycolysis↓, eff↑, OS↑, QoL↑, toxicity↝,
5266- 3BP,    3-bromopyruvate-based agent KAT-101
- Review, Var, NA
eff↑, Glycolysis↓, OXPHOS↓, ATP↓, TumCP↓, Apoptosis↑, HK2↓, MPT↑, LDH↓, PDH↓,
4774- 5-FU,  TQ,  CoQ10,    Exploring potential additive effects of 5-fluorouracil, thymoquinone, and coenzyme Q10 triple therapy on colon cancer cells in relation to glycolysis and redox status modulation
- in-vitro, CRC, NA
AntiCan↑, TumCCA↑, Apoptosis↑, eff↑, Bcl-2↓, survivin↓, P21↑, p27↑, BAX↑, Cyt‑c↑, Casp3↑, PI3K↓, Akt↓, mTOR↓, Hif1a↓, PTEN↑, AMPKα↑, PDH↑, LDHA↓, antiOx↓, ROS↑, AntiCan↑,
3941- 5HT,  dietMed,  VitB12,  FA,  VitC  Nutrition strategies that improve cognitive function
- Review, AD, NA
*other↑, *other↓, *cognitive↑, *eff↑, *eff↑,
3968- ACNs,    Enhanced Neuronal Activation with Blueberry Supplementation in Mild Cognitive Impairment
- Human, AD, NA
*BOLD↑, *cognitive?, *eff↑,
3973- ACNs,    Saskatoon and wild blueberries have higher anthocyanin contents than other Manitoba berries
- Analysis, AD, NA
eff↑,
1900- AF,    Potential Anticancer Activity of Auranofin
- Review, Var, NA
TrxR↓, ROS↑, Apoptosis↓, TumCP↓, eff↑,
5459- AF,    Auranofin Induces Lethality Driven by Reactive Oxygen Species in High-Grade Serous Ovarian Cancer Cells
- in-vitro, Ovarian, NA
ROS↑, TrxR↓, MMP↓, Apoptosis↑, eff↓, Casp3↑, Casp7↑, DNAdam↑, eff↑, GSH↓, angioG↓, ChemoSen↑, cl‑PARP↑, eff↑,
5460- AF,    Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species
- vitro+vivo, Var, 4T1
RadioS↑, ROS↑, eff↓, mt-OCR↓, DNAdam↑, Apoptosis↑, TrxR↓, eff↑,
5469- AF,    Ligand supplementation restores the cancer therapy efficacy of the antirheumatic drug auranofin from serum inactivation
- in-vitro, CRC, HCT116
eff↑, Half-Life↑,
5468- AF,    The gold complex auranofin: new perspectives for cancer therapy
- Review, Var, NA
TrxR↓, ROS↑, eff↑, Apoptosis↑, TumCG↓, TumCP↓, Akt↓, NF-kB↓, DNAdam↑, eff↝, eff↓, PI3K↓, Akt↓, mTOR↓, Hif1a↓, VEGF↓, Casp3↑, CSCs↓, ATP↓, Glycolysis↓, eff↑, eff↑, MMP↓, AIF↑, toxicity↓,
5467- AF,    Auranofin Inhibition of Thioredoxin Reductase Sensitizes Lung Neuroendocrine Tumor Cells (NETs) and Small Cell Lung Cancer (SCLC) Cells to Sorafenib as well as Inhibiting SCLC Xenograft Growth
- in-vitro, Lung, NA
TrxR↓, eff↑, Dose↝, OS↑, eff↑,
5444- AG,    A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine
- Review, Var, NA
*Imm↑, *antiOx↑, *Inflam↓, AntiTum↑, eff↑, chemoP↑, Dose↝, TumCMig↓, TumCP↓, Akt↓, GSK‐3β↓, MMP2↓, MMP9↓, EMT↓, PI3K↓, Akt↓, NF-kB↓, Inflam↓, TGF-β1↓, TNF-α↓, IL6↓, Fas↓, FasL↓, NOTCH1↓, JNK↓, TumCG↓,
5431- AG,    Advances in research on the anti-tumor mechanism of Astragalus polysaccharides
- Review, Var, NA
AntiTum↑, TumCG↓, TumCI↓, Apoptosis↑, Imm↑, Bcl-2↓, BAX↑, Wnt↓, β-catenin/ZEB1↓, TumCG↓, miR-133a-3p↑, JNK↓, Fas↑, P53↑, P21↑, NOTCH1↓, NOTCH3↓, TumCP↓, TumCCA↑, GPx4↓, xCT↓, AMPK↑, Beclin-1↑, NF-kB↓, EMT↓, Vim↓, TumMeta↓, VEGF↓, EGFR↓, eff↑, eff↑, MMP↓, P-gp↓, MMP9↓, ChemoSen↑, SIRT1↓, SREBP1↓, TumAuto↑, PI3K↓, mTOR↓, Casp3↑, Casp9↑, CD133↓, CD44↓, CSCs↓, QoL↑,
5432- AG,    Astragalus polysaccharides combined with radiochemotherapy for cervical cancer: a systematic review and meta-analysis of randomized controlled studies
- Review, Cerv, NA
ChemoSen↑, eff↑, RadioS↑, CEA↓, Wnt↓, β-catenin/ZEB1↓, γH2AX↑, ER Stress↑, mt-TumAuto↑, QoL↑, Imm↑,
5434- AG,    Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview
- Review, Liver, NA
AntiCan↑, Apoptosis↑, TumCP↓, EMT↓, Imm↑, ChemoSen↑, BioAv↓, TumCG↓, IL2↑, IL12↑, TNF-α↑, P-gp↓, MDR1↓, QoL↑, Casp↑, DNAdam↑, Bcl-2↓, BAX↑, MMP↓, Cyt‑c↑, NOTCH1↓, GSK‐3β↓, TumCCA↑, GSH↓, ROS↑, lipid-P↑, c-Iron↑, GPx4↓, ACSL4↑, Ferroptosis↑, Wnt↓, β-catenin/ZEB1↓, cycD1/CCND1↓, Akt↓, PI3K↓, mTOR↓, CXCR4↓, Vim↓, PD-L1↓, eff↑, eff↑, ChemoSen↑, ChemoSen↑, chemoP↑,
5441- AG,  Chemo,    Astragalus-containing Chinese herbal combinations for advanced non-small-cell lung cancer: a meta-analysis of 65 clinical trials enrolling 4751 patients
- Review, Lung, NA
eff↑, ChemoSen↑,
326- AgNPs,  TSA,    Modulating chromatin structure and DNA accessibility by deacetylase inhibition enhances the anti-cancer activity of silver nanoparticles
- in-vitro, Cerv, HeLa
Apoptosis↑, ChrMod↝, eff↑,
312- AgNPs,  wortm,    Inhibition of autophagy enhances the anticancer activity of silver nanoparticles
- vitro+vivo, Cerv, HeLa
APA↑, p62↓, PIK3CA↑, TumVol↓, TumAuto↑, eff↑,
306- AgNPs,    Cancer Therapy by Silver Nanoparticles: Fiction or Reality?
- Analysis, NA, NA
EPR↝, ROS↑, IL1↑, IL8↑, ER Stress↑, MMP9↑, MMP↓, Cyt‑c↑, Apoptosis↑, Hif1a↑, BBB↑, GutMicro↝, eff↑, eff↑, RadioS↑,
356- AgNPs,  MF,    Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study
- in-vitro, BC, MCF7 - in-vitro, Bladder, HTB-22
Apoptosis↑, P53↑, iNOS↑, NF-kB↑, Bcl-2↓, ROS↑, SOD↑, TumCCA↑, eff↑, Catalase↑, other↑,
5975- AgNPs,  PDT,  CDT,  RF,    Recent Advances in the Application of Silver Nanoparticles for Enhancing Phototherapy Outcomes
- Review, Var, NA - Review, BPH, NA
ROS↑, EPR↓, eff↑, Bacteria↓, eff↑, eff↑, TumVol↓,
5976- AgNPs,    Review on Harnessing Silver Nanoparticles for Therapeutic Innovations: A Comprehensive Review on Medical Applications, Safety, and Future Directions
- Review, Vit, NA
*Bacteria↓, AntiCan↑, *Inflam↓, *Wound Healing↑, eff↑, ChemoSen↑, EGFR↓, ROS↑, P53↑, BAX↑, Casp3↑, toxicity↝,
5977- AgNPs,  CDT,    Silver Nitroprusside as an Efficient Chemodynamic Therapeutic Agent and a Peroxynitrite nanogenerator for Targeted Cancer Therapy
- in-vivo, Ovarian, A2780S - NA, Ovarian, SKOV3
Fenton↑, ROS↑, eff↑, angioG↓, p‑Akt↓, EPR↑, selectivity↑, selectivity↑, eff↑, Cyt‑c↑, HO-1↑,
4403- AgNPs,    Silver Nanoparticles Decorated UiO-66-NH2 Metal-Organic Framework for Combination Therapy in Cancer Treatment
- in-vitro, GBM, U251 - in-vitro, GBM, U87MG - in-vitro, GBM, GL26 - in-vitro, Cerv, HeLa - in-vitro, CRC, RKO
AntiCan↑, eff↑, EPR↑, selectivity↑, ROS↑, Casp↑, Apoptosis↑, DNAdam↑, tumCV↓, eff↑,
4404- AgNPs,  Rad,    Main Approaches to Enhance Radiosensitization in Cancer Cells by Nanoparticles: A Systematic Review
- Review, Var, NA
eff↑, ROS↑,
4400- AgNPs,  Rad,    Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells
- in-vitro, BC, MCF7 - in-vitro, Nor, MCF10 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, BT549 - in-vivo, BC, MDA-MB-231
ROS↑, DNAdam↑, selectivity↑, TumCG↓, RadioS↑, Dose↝, selectivity↑, other↝, eff↓, eff↑, γH2AX↑, Dose↓, eff↑,
4399- AgNPs,  Chit,    Silver nanoparticles impregnated alginate-chitosan-blended nanocarrier induces apoptosis in human glioblastoma cells
- in-vitro, GBM, U87MG
DNAdam↑, ROS↑, MMP↓, eff↑,
4398- AgNPs,    Induction of apoptosis in cancer cells at low silver nanoparticle concentrations using chitosan nanocarrier
- in-vitro, Colon, HT29
Apoptosis↑, MMP↓, Casp3↑, ROS↑, eff↑,
4423- AgNPs,    Pongamia pinnata seed extract-mediated green synthesis of silver nanoparticle loaded nanogel for estimation of their antipsoriatic properties
- in-vivo, PSA, NA
*eff↑, *other↑,
4424- AgNPs,    Understanding the prospective of nano-formulations towards the treatment of psoriasis
- in-vivo, PSA, NA
*eff↑,
4415- AgNPs,  SDT,  CUR,    Examining the Impact of Sonodynamic Therapy With Ultrasound Wave in the Presence of Curcumin-Coated Silver Nanoparticles on the Apoptosis of MCF7 Breast Cancer Cells
- in-vitro, BC, MCF7
tumCV↓, BAX↑, Casp3↑, Bcl-2↓, eff↑, ROS↑, sonoS↑, eff↑, MMP↓, Cyt‑c↑,
4413- AgNPs,  Anzaroot,    Green synthesis of silver nanoparticles from plant Astragalus fasciculifolius Bioss and evaluating cytotoxic effects on MCF7 human breast cancer cells
- in-vitro, BC, MCF7
chemoP↑, TumCG↓, eff↑, CellMemb↑, selectivity↑, ROS↑, P53↑,

Showing Research Papers: 1 to 50 of 1048
Page 1 of 21 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1048

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   Catalase↑, 1,   Fenton↑, 1,   Ferroptosis↓, 1,   Ferroptosis↑, 1,   GPx↓, 1,   GPx4↓, 2,   GSH↓, 5,   H2O2↑, 1,   HO-1↑, 1,   c-Iron↑, 1,   lipid-P↑, 1,   MDA↑, 1,   MFN2↑, 1,   OXPHOS↓, 4,   ROS↑, 24,   SOD↑, 1,   TrxR↓, 5,   xCT↓, 1,   xCT↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 2,   ATP↓, 7,   MMP↓, 8,   MPT↑, 1,   mt-OCR↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACSL4↑, 1,   AMPK↑, 1,   ECAR↓, 1,   GAPDH↓, 2,   Glycolysis↓, 10,   HK2?, 1,   HK2↓, 6,   LDH↓, 2,   LDHA↓, 2,   PDH↓, 1,   PDH↑, 1,   PIK3CA↑, 1,   PKM2↓, 1,   PPP↑, 1,   SIRT1↓, 1,   SREBP1↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 7,   p‑Akt↓, 1,   p‑Akt↑, 1,   Apoptosis↓, 1,   Apoptosis↑, 15,   BAX↑, 6,   Bcl-2↓, 5,   Casp↑, 2,   Casp3↑, 7,   cl‑Casp3⇅, 1,   Casp7↑, 1,   Casp9↑, 2,   Cyt‑c↑, 8,   Fas↓, 1,   Fas↑, 1,   FasL↓, 1,   Ferroptosis↓, 1,   Ferroptosis↑, 1,   iNOS↑, 1,   JNK↓, 3,   MAPK↝, 1,   p27↑, 1,   p38↑, 1,   survivin↓, 2,   TumCD↑, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

AMPKα↑, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ChrMod↝, 1,   other↑, 1,   other↝, 1,   PhotoS↑, 1,   sonoS↑, 1,   tumCV↓, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 3,  

Autophagy & Lysosomes(tgid=9) ⓘ

APA↑, 1,   Beclin-1↑, 1,   p‑Beclin-1↑, 1,   p62↓, 1,   TumAuto↑, 3,   mt-TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 9,   P53↑, 5,   cl‑PARP↑, 2,   γH2AX↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   P21↑, 2,   TumCCA↑, 5,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 1,   CD44↓, 1,   CSCs↓, 2,   EMT↓, 3,   FOXO3↑, 1,   GSK‐3β↓, 2,   GSK‐3β↑, 1,   mTOR↓, 4,   mTOR↝, 1,   NOTCH1↓, 3,   NOTCH3↓, 1,   PI3K↓, 5,   PTEN↑, 1,   TumCG↓, 9,   Wnt↓, 4,  

Migration(tgid=13) ⓘ

CEA↓, 1,   fascin↓, 1,   miR-133a-3p↑, 1,   MMP2↓, 1,   MMP9↓, 4,   MMP9↑, 1,   TGF-β↓, 1,   TGF-β1↓, 1,   TumCI↓, 2,   TumCMig↓, 1,   TumCP↓, 6,   TumMeta↓, 2,   Vim↓, 2,   β-catenin/ZEB1↓, 4,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 3,   EGFR↓, 2,   EPR↓, 1,   EPR↑, 2,   EPR↝, 1,   Hif1a↓, 2,   Hif1a↑, 1,   VEGF↓, 3,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   CellMemb↑, 2,   P-gp↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 1,   CXCR4↓, 1,   IL1↑, 1,   IL12↑, 1,   IL2↑, 1,   IL6↓, 1,   IL8↑, 1,   Imm↑, 3,   Inflam↓, 1,   NF-kB↓, 3,   NF-kB↑, 1,   NK cell↑, 1,   PD-L1↓, 1,   TNF-α↓, 1,   TNF-α↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↝, 1,   ChemoSen↑, 9,   Dose↓, 1,   Dose↝, 9,   eff↓, 7,   eff↑, 58,   eff↝, 2,   Half-Life↑, 1,   MDR1↓, 1,   RadioS↑, 6,   selectivity↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

CEA↓, 1,   EGFR↓, 2,   GutMicro↝, 1,   IL6↓, 1,   LDH↓, 2,   PD-L1↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 6,   AntiTum↑, 3,   chemoP↑, 3,   OS↑, 3,   QoL↑, 4,   toxicity↓, 7,   toxicity↑, 4,   toxicity↝, 3,   TumVol↓, 3,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,  
Total Targets: 171

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,   TRPA1↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 3,   Catalase↑, 1,   GPx↑, 1,   HO-1↑, 1,   lipid-P↓, 2,   MDA↓, 1,   NRF2↑, 2,   ROS↓, 1,   SOD↑, 1,   TAC↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

NADPH↑, 1,   PPARγ↓, 1,   PPARγ↑, 1,  

Cell Death(tgid=5) ⓘ

MAPK↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 1,   other↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↓, 1,   GSK‐3β↓, 2,  

Migration(tgid=13) ⓘ

VCAM-1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ICAM-1↓, 1,   IL1β↓, 3,   IL4↓, 1,   IL6↓, 2,   Imm↑, 1,   Inflam↓, 5,   MUC2↓, 1,   NF-kB↓, 2,   PGE2↓, 2,   TNF-α↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   Aβ↓, 1,   BACE↓, 1,   NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 3,   eff↑, 7,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

IL6↓, 2,   MUC19↓, 1,  

Functional Outcomes(tgid=23) ⓘ

BOLD↑, 1,   cardioP↑, 1,   cognitive?, 1,   cognitive↑, 1,   neuroP↑, 2,   toxicity↓, 2,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 2,   AntiViral↑, 2,   Bacteria↓, 2,  
Total Targets: 53

Scientific Paper Hit Count for: eff, efficacy
52 Silver-NanoParticles
37 Magnetic Fields
37 Curcumin
29 Vitamin C (Ascorbic Acid)
29 immunotherapy
28 Chemotherapy
26 Sulforaphane (mainly Broccoli)
25 chitosan
21 Thymoquinone
21 EGCG (Epigallocatechin Gallate)
21 Selenium NanoParticles
20 Resveratrol
19 Quercetin
18 Artemisinin
18 Chrysin
17 Dichloroacetate
16 Copper and Cu NanoParticles
16 Metformin
16 Chlorogenic acid
15 Radiotherapy/Radiation
15 Capsaicin
15 diet FMD Fasting Mimicking Diet
15 Bicarbonate(Sodium)
14 Berberine
14 Lycopene
13 3-bromopyruvate
13 Caffeic acid
13 Exercise
13 Magnetic Field Rotating
13 Piperlongumine
12 Phenylbutyrate
11 Citric Acid
11 Baicalein
11 Rosmarinic acid
11 Selenite (Sodium)
10 Melatonin
10 Apigenin (mainly Parsley)
10 Ashwagandha(Withaferin A)
10 Atorvastatin
10 Propolis -bee glue
10 Dandelion Root
10 Shikonin
9 Cisplatin
9 borneol
9 Carvacrol
9 Choline
9 Gambogic Acid
8 Auranofin
8 SonoDynamic Therapy UltraSound
8 Alpha-Lipoic-Acid
8 Luteolin
8 Boron
8 Ellagic acid
8 Chlorophyllin
8 Selenium
8 Silymarin (Milk Thistle) silibinin
8 Electrical Pulses
8 salinomycin
8 Fisetin
8 Honokiol
8 Urolithin
8 VitK3,menadione
7 Photodynamic Therapy
7 Hyperthermia
7 Gold NanoParticles
7 Vitamin D3
7 Vitamin K2
7 Disulfiram
7 Eugenol
7 doxorubicin
6 5-fluorouracil
6 Docetaxel
6 Dipyridamole
6 beta-glucans
6 Bifidobacterium
6 Piperine
6 diet Methionine-Restricted Diet
6 HydroxyCitric Acid
6 Parthenolide
5 1,8-Cineole
5 Coenzyme Q10
5 Folic Acid, Vit B9
5 Astragalus
5 chemodynamic therapy
5 Fenbendazole
5 Akkermansia
5 Gemcitabine (Gemzar)
5 Aspirin
5 Ascorbyl Palmitate
5 Astaxanthin
5 Betulinic acid
5 beta-carotene(VitA)
5 Boswellia (frankincense)
5 Thymol-Thymus vulgaris
5 Centella asiatica / Gotu kola → asiaticoside
5 Diclofenac
5 Docosahexaenoic Acid
5 Echinacea
5 Hydrogen Gas
5 Spermidine
5 Magnolol
5 Phenethyl isothiocyanate
4 cetuximab
4 Berbamine
4 Bevacizumab (brand Avastin)
4 Bortezomib
4 Carnosic acid
4 Celastrol
4 CUSP9
4 erastin
4 diet Plant based
4 MCToil
4 Moringa oleifera
4 Pterostilbene
4 Terpinen-4-ol / Tea Tree Oil
3 2-DeoxyGlucose
3 Zinc
3 Allicin (mainly Garlic)
3 Andrographis
3 Biochanin A
3 Beta-Caryophyllene
3 bempedoic acid
3 Lutein
3 Zeaxanthin
3 temozolomide
3 α-Bisabolol / Chamomile oil
3 Butyrate
3 capecitabine
3 Cat’s Claw
3 Calorie Restriction Mimetics
3 Cysteamine
3 diet Short Term Fasting
3 Ginseng
3 Lecithin
3 nicotinamide adenine dinucleotide
3 Naringin
3 Nimbolide
3 Propyl gallate
3 Vitamin B1/Thiamine
3 Whole Body Vibration
2 Vitamin B12
2 Anthocyanins
2 Glucose
2 almonertinib
2 Trastuzumab
2 Arsenic trioxide
2 Aloe anthraquinones
2 Baicalin
2 D-limonene
2 Bufalin/Huachansu
2 brusatol
2 Rutin
2 hydroxychloroquine
2 carboplatin
2 Chocolate
2 Cichoric acid / Chicoric acid
2 Cinnamon
2 Hydroxycinnamic-acid
2 Crocetin
2 Cyclopamine
2 Dichloroacetophenone(2,2-)
2 Dasatinib/Phyrago
2 Oxygen, Hyperbaric
2 ferumoxytol
2 Genistein (soy isoflavone)
2 Orlistat
2 Potassium
2 Mushroom Lion’s Mane
2 Niclosamide (Niclocide)
2 Phosphatidylserine
2 Radio Frequency
2 Sulfasalazine
2 Taurine
1 Serotonin, 5-hydroxytryptamine
1 dietMediterranean
1 Trichostatin A
1 wortmannin
1 EMF
1 Anzaroot, Astragalus fasciculifolius Bioss
1 Ajoene (compound of Garlic)
1 Amodiaquine
1 Anethole/trans-Anethole
1 Fennel Oil/Foeniculum vulgare
1 Anti-oxidants
1 Aromatherapy
1 5-Aminolevulinic acid
1 Huperzine A/Huperzia serrata
1 probiotics
1 Bromelain
1 Bruteridin(bergamot juice)
1 Caffeic Acid Phenethyl Ester (CAPE)
1 urea
1 Sorafenib (brand name Nexavar)
1 Carnosine
1 Cannabidiol
1 Celecoxib
1 Beta‐Lapachone
1 Camptothecin
1 irinotecan
1 Carvone
1 Black phosphorus
1 Cucurbitacin
1 gefitinib, erlotinib
1 Deguelin
1 Date Fruit Extract
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 diet Ketogenic
1 Vitamin A, Retinoic Acid
1 Mistletoe
1 PXD, phenoxodiol
1 Emodin
1 Eurycomanone
1 Ferulic acid
1 Vitamin E
1 Flickering Light Stimulation
1 verapamil
1 Geraniol
1 tamoxifen
1 itraconazole
1 Juglone
1 Kaempferol
1 Laetrile B17 Amygdalin
1 Linalool
1 Methylene blue
1 metronomic chemo
1 Caffeine
1 methotrexate
1 Magnesium
1 Methylglyoxal
1 Methylsulfonylmethane
1 Mushroom Reishi
1 Myricetin
1 No Product/Mechanism Only
1 Oleocanthal
1 Peppermint
1 sericin
1 Paclitaxel
1 Psoralidin
1 enzalutamide
1 α-Santalol/Sandalwood oil
1 polyethylene glycol
1 acetaminophen
1 Formononetin
1 acetazolamide
1 Iron
1 Squalene
1 Glutathione
1 statins
1 Sutherlandioside D
1 Aflavin-3,3′-digallate
1 tetrathiomolybdate
1 triptolide
1 Turmerones
1 Vitamin B3,Niacin
1 Wogonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:961  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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