TumVol Cancer Research Results

TumVol, Tumor Volume: Click to Expand ⟱
Source:
Type:
Tumor Volume
Scientific Papers found: Click to Expand⟱
5263- 3BP,  CET,    3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis
- in-vitro, CRC, DLD1 - NA, NA, HCT116
eff↑, Ferroptosis↓, TumAuto↑, Apoptosis↑, FOXO3↑, AMPKα↑, p‑Beclin-1↑, HK2↓, ATP↓, ROS↑, Dose↝, TumVol↓, TumW↓, xCT↑, GSH↓, eff↓, MDA↑,
4394- AgNPs,    Silver nanoparticles provoke apoptosis of Dalton's ascites lymphoma in vivo by mitochondria dependent and independent pathways
- in-vivo, lymphoma, NA
OS↑, TumVol↓, Weight↑, AntiTum↑, Apoptosis↑, mtDam↑,
4431- AgNPs,  doxoR,    Oxidative Stress-Induced Silver Nano-Carriers for Chemotherapy
- in-vitro, BC, 4T1 - in-vivo, BC, 4T1 - in-vitro, Nor, 3T3
AntiCan↑, ROS↑, TumVol↓, EPR↑, selectivity↑, ChemoSen↑,
4361- AgNPs,  GoldNP,    Biocompatible silver, gold and silver/gold alloy nanoparticles for enhanced cancer therapy: in vitro and in vivo perspectives
- in-vivo, Liver, HepG2
TumCD↑, TumVol↓, *toxicity↝, hepatoP↑,
4363- AgNPs,    Immunomodulatory properties of silver nanoparticles contribute to anticancer strategy for murine fibrosarcoma
- in-vivo, fibroS, NA
TumVol↓, TNF-α↓, IL6↓, IL1β↓, *toxicity↝, TumCG↓, selectivity↑, selectivity↑, Weight↑, ROS↑, NO↑,
312- AgNPs,  wortm,    Inhibition of autophagy enhances the anticancer activity of silver nanoparticles
- vitro+vivo, Cerv, HeLa
APA↑, p62↓, PIK3CA↑, TumVol↓, TumAuto↑, eff↑,
362- AgNPs,    Comparative and Mechanistic Study on the Anticancer Activity of Quinacrine-Based Silver and Gold Hybrid Nanoparticles in Head and Neck Cancer
- vitro+vivo, SCC, SCC9
DNAdam↑, TumVol↓,
378- AgNPs,    Antitumor efficacy of silver nanoparticles reduced with β-D-glucose as neoadjuvant therapy to prevent tumor relapse in a mouse model of breast cancer
- ex-vivo, BC, 4T1
TumVol↓, TumMeta↓, Ki-67↓,
390- AgNPs,    Anti-cancerous effect of albumin coated silver nanoparticles on MDA-MB 231 human breast cancer cell line
- in-vitro, BC, MDA-MB-231 - in-vivo, BC, NA
ROS↑, TumVol↓,
5342- Ajoene,    The garlic-derived organosulfur component ajoene decreases basal cell carcinoma tumor size by inducing apoptosis
- in-vivo, BCC, NA
TumVol↓, Bcl-2↓, Apoptosis↑,
546- AL,    Effects of garlic intake on cancer: a systematic review of randomized clinical trials and cohort studies
- Review, NA, NA
Risk↓, TumVol↓,
1069- AL,    Allicin promotes autophagy and ferroptosis in esophageal squamous cell carcinoma by activating AMPK/mTOR signaling
- vitro+vivo, ESCC, TE1 - vitro+vivo, ESCC, KYSE-510 - in-vitro, Nor, Het-1A
TumCP↓, LC3‑Ⅱ/LC3‑Ⅰ↑, p62↓, p‑AMPK↑, mTOR↓, TumAuto↑, NCOA4↑, MDA↑, Iron↑, TumW↓, TumVol↓, ATG5↑, ATG7↑, TfR1/CD71↓, FTH1↓, ROS↑, Iron↑, Ferroptosis↑, *toxicity↓,
271- ALA,  VitC,  LDN,    The Long-Term Survival of a Patient With Stage IV Renal Cell Carcinoma Following an Integrative Treatment Approach Including the Intravenous α-Lipoic Acid/Low-Dose Naltrexone Protocol
OS↑, Weight↑, TumVol↓,
1546- Api,    Apigenin in Cancer Prevention and Therapy: A Systematic Review and Meta-Analysis of Animal Models
- Review, NA, NA
TumVol↓, TumW↓, AntiCan↑, Apoptosis↑, TumCCA↑,
1553- Api,    Role of Apigenin in Cancer Prevention via the Induction of Apoptosis and Autophagy
- Review, NA, NA
Dose∅, TumVol↓, Dose∅, COX2↓, Hif1a↓, TumCCA↑, P53↑, P21↑, Casp3↑, DNAdam↑, TumAuto↝,
1564- Api,    Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation
- in-vitro, Pca, 22Rv1 - in-vivo, NA, NA
MDM2↓, NF-kB↓, p65↓, P21↑, ROS↑, GSH↓, MMP↓, Cyt‑c↑, Apoptosis↑, P53↑, eff↓, Bcl-xL↓, Bcl-2↓, BAX↑, Casp↑, TumCG↓, TumVol↓, TumW↓,
2319- Api,    Apigenin sensitizes radiotherapy of mouse subcutaneous glioma through attenuations of cell stemness and DNA damage repair by inhibiting NF-κB/HIF-1α-mediated glycolysis
- in-vitro, GBM, NA
Glycolysis↓, NF-kB↓, p65↓, Hif1a↓, GLUT1↓, GLUT3↓, PKM2↓, RadioS↑, TumVol↓, TumW↓,
177- Api,    Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21WAF1/CIP1 expression
- in-vitro, BC, MDA-MB-231
Cyc↓, CycB/CCNB1↓, CDK1↓, P21↑, PCNA↝, HDAC↓, TumCP↓, TumCCA↑, ac‑H3↑, TumW↓, TumVol↓,
3391- ART/DHA,    Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug
- Review, Var, NA
TumCP↓, TumMeta↓, angioG↓, TumVol↓, BioAv↓, Half-Life↓, BioAv↑, eff↑, eff↓, ROS↑, selectivity↑, TumCCA↑, survivin↓, BAX↑, Casp3↓, Casp8↑, Casp9↑, CDC25↓, CycB/CCNB1↓, NF-kB↓, cycD1/CCND1↓, cycE/CCNE↓, E2Fs↓, P21↑, p27↑, ADP:ATP↑, MDM2↓, VEGF↓, IL8↓, COX2↓, MMP9↓, ER Stress↓, cMyc↓, GRP78/BiP↑, DNAdam↑, AP-1↓, MMP2↓, PKCδ↓, Raf↓, ERK↓, JNK↓, PCNA↓, CDK2↓, CDK4↓, TOP2↓, uPA↓, MMP7↓, TIMP2↑, Cdc42↑, E-cadherin↑,
1179- Ash,    Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity
- in-vitro, CRC, HCT116 - in-vivo, NA, NA
TumCP↓, TumCMig↓, STAT3↓, TumVol↓, TumW↓,
1177- Ash,    Withaferin A downregulates COX-2/NF-κB signaling and modulates MMP-2/9 in experimental endometriosis
- in-vivo, EC, NA
TumVol↓, MMP2↓, MMP9↓, NF-kB↓, COX2↓, NO↓, IL1β↓, IL6↓,
1176- Ash,    Metabolic Alterations in Mammary Cancer Prevention by Withaferin A in a Clinically Relevant Mouse Model
- in-vivo, NA, NA
TumVol↓, Apoptosis↑, Glycolysis↓, PKM2↓, PGK1↓, ALDOAiso2↓,
5499- Ba,    Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo
- vitro+vivo, Lung, H460 - vitro+vivo, Lung, A549
TumCP↓, Apoptosis↑, F-actin↓, TumVol↓, OS↑, 12LOX↓, VEGF↓, angioG↓,
2599- Ba,    Baicalein induces apoptosis and autophagy of breast cancer cells via inhibiting PI3K/AKT pathway in vivo and vitro
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
TumCP↓, Apoptosis↑, p‑Akt↓, p‑mTOR↓, NF-kB↓, p‑IKKα↓, IKKα↑, PI3K↓, MMP↓, TumAuto↑, TumVol↓, TumW↓,
5539- BBM,    Berbamine suppresses cell viability and induces apoptosis in colorectal cancer via activating p53-dependent apoptotic signaling pathway
- vitro+vivo, CRC, SW480
tumCV↓, TumCCA↑, MMP↓, P53↑, Casp3↑, Casp9↑, BAX↑, PARP↑, Bcl-2↓, TumVol↑,
5551- BBM,    Berbamine Suppresses the Progression of Bladder Cancer by Modulating the ROS/NF-κB Axis
- vitro+vivo, Bladder, NA
tumCV↓, TumCP↓, TumCCA↑, P21↑, p27↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, EMT↓, TumMeta↓, p65↓, p‑p65↓, IKKα↓, NF-kB↑, ROS↑, NRF2↓, HO-1↓, SOD2↓, GPx1↓, Bax:Bcl2↑, TumVol↓,
940- BBR,    Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression
- vitro+vivo, PC, PANC1 - in-vivo, PC, MIA PaCa-2
LDHA↓, lactateProd↓, AMPKα↓, TumVol↓, Ki-67↓,
5176- BBR,    Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice
- vitro+vivo, CRC, HCT116 - in-vitro, CRC, SW480 - in-vitro, CRC, LoVo
TumVol↓, Ki-67↓, COX2↓, AMPK↑, mTOR↓, NF-kB↓, cycD1/CCND1↓, survivin↓, P53↑, cl‑Casp3↑, TumCP↓, Inflam↓, COX2↓, ACC↑,
2717- BetA,    Betulinic Acid Induces ROS-Dependent Apoptosis and S-Phase Arrest by Inhibiting the NF-κB Pathway in Human Multiple Myeloma
- in-vitro, Melanoma, U266 - in-vivo, Melanoma, NA - in-vitro, Melanoma, RPMI-8226
Apoptosis↑, TumCCA↑, MMP↓, ROS↑, eff↓, NF-kB↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, cl‑PARP1↑, MDA↑, SOD↓, SOD2↓, GCLM↓, GSTA1↓, FTH1↓, GSTs↓, TumVol↓,
2733- BetA,    Betulinic Acid Inhibits Cell Proliferation in Human Oral Squamous Cell Carcinoma via Modulating ROS-Regulated p53 Signaling
- in-vitro, Oral, KB - in-vivo, NA, NA
TumCP↓, TumVol↓, mt-Apoptosis↑, Casp3↑, Casp9↑, BAX↑, Bcl-2↑, OCR↓, TumCCA↑, ROS↑, eff↓, P53↑, STAT3↓, cycD1/CCND1↑,
2746- BetA,    Betulinic acid induces apoptosis and inhibits metastasis of human colorectal cancer cells in vitro and in vivo
- in-vitro, CRC, HCT116 - in-vivo, CRC, NA
TumCG↓, BAX↑, Bcl-2↓, ROS↑, MMP↓, TIMP2↑, TumVol↓,
5692- BJ,    Seed oil of Brucea javanica induces apoptosis through the PI3K/Akt signaling pathway in acute lymphocytic leukemia Jurkat cells
- vitro+vivo, AML, NA
Apoptosis↑, Akt↓, P53↑, FOXO1↑, GSK‐3β↑, TumVol↓, QoL↑, BBB↑, OS↑, Dose↝, MMP↓, ROS↑, XIAP↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, TumCCA↑,
5683- BML,    Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumor-initiation triggering mitochondrial death pathway
- in-vitro, NA, NA
COX2↓, MAPK↓, NF-kB↓, TumMeta↓, P53↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, MAPK↓, ERK↓, Akt↓, TumVol↓,
5658- BNL,    Natural borneol is a novel chemosensitizer that enhances temozolomide-induced anticancer efficiency against human glioma by triggering mitochondrial dysfunction and reactive oxide species-mediated oxidative damage
- vitro+vivo, GBM, U251
ChemoSen↑, mt-Apoptosis↑, Casp↑, DNAdam↑, ROS↑, angioG↓, BBB↑, EPR↑, TumVol↓, TumW↓, BioEnh↑,
3518- Bor,    Boron Report
- Review, Var, NA - Review, AD, NA
Risk↓, serineP↓, PSA↓, TumVol↓, IGF-1↓, *Mag↑, *Calcium↑, *VitD↑, *COX2↓, *5LO↓, *PGE2↓, *NF-kB↓, *cognitive↑,
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,
746- Bor,    Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope
- Review, NA, NA
eff↑, *toxicity↓, ROS↑, LAT↓, AntiCan↑, AR↓, PSMB5↓, IGF-1↓, PSA↓, TumVol↓, eff↑, Rho↓, Cdc42↓, Ca+2↓, eff↑,
706- Bor,    Boron supplementation inhibits the growth and local expression of IGF-1 in human prostate adenocarcinoma (LNCaP) tumors in nude mice
- in-vivo, Pca, LNCaP
TumVol↓, IGF-1↓, PSA↓,
4624- Bor,  VitD3,    Boron as a Medicinal Ingredient in Oral Natural Health Products
- Review, Pca, NA
*Half-Life↝, *eff↑, PSA↓, TumVol↓, IGF-1↓, *memory↓, *motorD↓,
1169- Bos,    Boswellic Acid Inhibits Growth and Metastasis of Human Colorectal Cancer in Orthotopic Mouse Model By Downregulating Inflammatory, Proliferative, Invasive, and Angiogenic Biomarkers
- in-vivo, CRC, NA
TumCG↓, TumVol↓, Weight∅, ascitic↓, TumMeta↓, Ki-67↓, CD31↓, NF-kB↓, COX2↓, Bcl-2↓, Bcl-xL↓, IAP1↓, survivin↓, cycD1/CCND1↓, ICAM-1↓, MMP9↓, CXCR4↓, VEGF↓,
1230- CA,  Caff,    Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - Human, NA, NA
TumVol↓, TumCG↓, ER(estro)↓, cycD1/CCND1↓, IGF-1R↓, p‑Akt↓,
5749- CA,  Z,  Rad,    Antitumor and Radiosensitizing Effects of Zinc Oxide-Caffeic Acid Nanoparticles against Solid Ehrlich Carcinoma in Female Mice
- vitro+vivo, BC, MCF-7 - NA, Liver, HepG2
RadioS↑, TumVol↓, Bcl-2↓, NF-kB↓, VCAM-1↓, ERK↓, DNAdam↑, TumCCA↑,
2013- CAP,    Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cells
- in-vitro, Pca, PC3 - in-vitro, Pca, LNCaP - in-vitro, Pca, DU145 - in-vivo, NA, NA
TumCP↓, P53↑, P21↑, BAX↑, PSA↓, AR↓, NF-kB↓, Proteasome↓, TumVol↓, eff∅,
1103- CBD,    Cannabidiol inhibits invasion and metastasis in colorectal cancer cells by reversing epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway
- vitro+vivo, NA, NA
Apoptosis↑, TumCP↓, TumCMig↓, TumMeta↓, EMT↓, E-cadherin↑, N-cadherin↓, Snail↓, Vim↓, Hif1a↓, Wnt/(β-catenin)↓, AXIN1↑, TumVol↓, TumW↓,
1106- CGA,    Chlorogenic Acid Inhibits Epithelial-Mesenchymal Transition and Invasion of Breast Cancer by Down-Regulating LRP6
- vitro+vivo, BC, MCF-7
E-cadherin↑, ZO-1↑, Zeb1↓, N-cadherin↓, Vim↓, Snail↓, Slug↓, MMP2↓, MMP9↓, TumCMig↓, TumCI↓, LRP6↓, p‑LRP6↓, β-catenin/ZEB1↓, TumVol↓, TumW↓,
2784- CHr,    Chrysin targets aberrant molecular signatures and pathways in carcinogenesis (Review)
- Review, Var, NA
Apoptosis↑, TumCMig↓, *toxicity↝, ChemoSen↑, *BioAv↓, Dose↝, neuroP↑, *P450↓, *ROS↓, *HDL↑, *GSTs↑, *SOD↑, *Catalase↑, *MAPK↓, *NF-kB↓, *PTEN↑, *VEGF↑, ROS↑, MMP↓, Ca+2↑, selectivity↑, PCNA↓, Twist↓, EMT↓, CDKN1C↑, p‑STAT3↑, MMP2↓, MMP9↓, eff↑, cycD1/CCND1↓, hTERT/TERT↓, CLDN1↓, TumVol↓, OS↑, COX2↓, eff↑, CDK2↓, CDK4↓, selectivity↑, TumCCA↑, E-cadherin↑, HK2↓, HDAC↓,
141- CUR,    Effect of curcumin on Bcl-2 and Bax expression in nude mice prostate cancer
- in-vivo, Pca, PC3
BAX↑, Bcl-2↓, TumCG↓, TumVol↓, TumW↓, Apoptosis↑, AR↓, Ca+2↑, MPT↑,
9- CUR,    Curcumin Suppresses Malignant Glioma Cells Growth and Induces Apoptosis by Inhibition of SHH/GLI1 Signaling Pathway in Vitro and Vivo
- vitro+vivo, MG, U87MG - vitro+vivo, MG, T98G
HH↓, Shh↓, Gli1↓, cycD1/CCND1↓, Bcl-2↓, FOXM1↓, Bax:Bcl2↑, TumCP↓, TumCMig↓, Apoptosis↑, TumVol↑, TumCCA↑, Casp3↑, OS↑,
483- CUR,  PDT,    Visible light and/or UVA offer a strong amplification of the anti-tumor effect of curcumin
- in-vivo, NA, A431
TumVol↓, TumCP↓, Apoptosis↑,
437- CUR,    Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids
- vitro+vivo, CRC, TCO1 - vitro+vivo, CRC, TCO2
cycD1/CCND1↓, cMyc↓, p‑ERK↓, CD44↓, CD133↓, LGR5↓, TumCCA↑, TumVol↓, CSCs↓,

Showing Research Papers: 1 to 50 of 132
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 132

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↓, 1,   Ferroptosis↑, 1,   GCLM↓, 1,   GPx1↓, 1,   GSH↓, 2,   GSTA1↓, 1,   GSTs↓, 1,   HO-1↓, 1,   Iron↑, 2,   MDA↑, 3,   NRF2↓, 1,   ROS↑, 15,   SOD↓, 1,   SOD2↓, 2,   xCT↑, 1,  

Metal & Cofactor Biology ⓘ

FTH1↓, 2,   NCOA4↑, 1,   TfR1/CD71↓, 1,  

Mitochondria & Bioenergetics ⓘ

ADP:ATP↑, 1,   ATP↓, 1,   CDC25↓, 1,   MMP↓, 7,   MPT↑, 1,   mtDam↑, 1,   OCR↓, 1,   Raf↓, 1,   XIAP↑, 1,  

Core Metabolism/Glycolysis ⓘ

12LOX↓, 1,   ACC↑, 1,   ALDOAiso2↓, 1,   AMPK↑, 1,   p‑AMPK↑, 1,   ATG7↑, 1,   cMyc↓, 2,   Glycolysis↓, 2,   HK2↓, 2,   lactateProd↓, 1,   LAT↓, 1,   LDHA↓, 1,   PGK1↓, 1,   PIK3CA↑, 1,   PKM2↓, 2,   PSMB5↓, 1,  

Cell Death ⓘ

Akt↓, 2,   p‑Akt↓, 2,   Apoptosis↑, 16,   mt-Apoptosis↑, 2,   BAX↑, 8,   Bax:Bcl2↑, 2,   Bcl-2↓, 9,   Bcl-2↑, 1,   Bcl-xL↓, 2,   Casp↑, 2,   Casp3↓, 1,   Casp3↑, 7,   cl‑Casp3↑, 1,   Casp8↑, 3,   Casp9↑, 6,   Cyt‑c↑, 2,   Ferroptosis↓, 1,   Ferroptosis↑, 1,   hTERT/TERT↓, 1,   IAP1↓, 1,   JNK↓, 1,   MAPK↓, 2,   MDM2↓, 2,   p27↑, 2,   Proteasome↓, 1,   survivin↓, 3,   TumCD↑, 1,  

Kinase & Signal Transduction ⓘ

AMPKα↓, 1,   AMPKα↑, 1,  

Transcription & Epigenetics ⓘ

ac‑H3↑, 1,   tumCV↓, 2,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,   GRP78/BiP↑, 1,  

Autophagy & Lysosomes ⓘ

APA↑, 1,   ATG5↑, 1,   p‑Beclin-1↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   p62↓, 2,   TumAuto↑, 4,   TumAuto↝, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 5,   P53↑, 8,   PARP↑, 1,   cl‑PARP↑, 1,   cl‑PARP1↑, 1,   PCNA↓, 2,   PCNA↝, 1,  

Cell Cycle & Senescence ⓘ

CDK1↓, 1,   CDK2↓, 3,   CDK4↓, 2,   Cyc↓, 2,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 2,   cycD1/CCND1↓, 8,   cycD1/CCND1↑, 1,   cycE/CCNE↓, 1,   E2Fs↓, 1,   P21↑, 6,   TumCCA↑, 13,  

Proliferation, Differentiation & Cell State ⓘ

AXIN1↑, 1,   CD133↓, 1,   CD44↓, 1,   CSCs↓, 1,   EMT↓, 3,   ERK↓, 3,   p‑ERK↓, 1,   FOXM1↓, 1,   FOXO1↑, 1,   FOXO3↑, 1,   Gli1↓, 1,   GSK‐3β↑, 1,   HDAC↓, 3,   HH↓, 1,   IGF-1↓, 5,   IGF-1R↓, 1,   LGR5↓, 1,   LRP6↓, 1,   p‑LRP6↓, 1,   mTOR↓, 2,   p‑mTOR↓, 1,   PI3K↓, 1,   Shh↓, 1,   STAT3↓, 2,   p‑STAT3↑, 1,   TOP2↓, 1,   TumCG↓, 6,   Wnt/(β-catenin)↓, 1,  

Migration ⓘ

AP-1↓, 1,   Ca+2↓, 1,   Ca+2↑, 2,   CD31↓, 1,   Cdc42↓, 1,   Cdc42↑, 1,   CDKN1C↑, 1,   CLDN1↓, 1,   E-cadherin↑, 4,   F-actin↓, 1,   Ki-67↓, 4,   MMP2↓, 4,   MMP7↓, 1,   MMP9↓, 5,   N-cadherin↓, 2,   PKCδ↓, 1,   Rho↓, 1,   serineP↓, 1,   Slug↓, 1,   Snail↓, 2,   TIMP2↑, 2,   TumCI↓, 1,   TumCMig↓, 6,   TumCP↓, 13,   TumMeta↓, 6,   Twist↓, 1,   uPA↓, 1,   VCAM-1↓, 1,   Vim↓, 2,   Zeb1↓, 1,   ZO-1↑, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 4,   EPR↑, 2,   HIF-1↓, 1,   Hif1a↓, 3,   NO↓, 1,   NO↑, 1,   VEGF↓, 3,  

Barriers & Transport ⓘ

BBB↑, 2,   GLUT1↓, 1,   GLUT3↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 8,   CXCR4↓, 1,   ICAM-1↓, 1,   IKKα↓, 1,   IKKα↑, 1,   p‑IKKα↓, 1,   IL1β↓, 2,   IL6↓, 2,   IL8↓, 1,   Inflam↓, 1,   NF-kB↓, 11,   NF-kB↑, 1,   p65↓, 3,   p‑p65↓, 1,   PSA↓, 6,   TNF-α↓, 1,  

Hormonal & Nuclear Receptors ⓘ

AR↓, 3,   ER(estro)↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↑, 1,   BioEnh↑, 1,   ChemoSen↑, 3,   Dose↝, 3,   Dose∅, 2,   eff↓, 5,   eff↑, 8,   eff∅, 1,   Half-Life↓, 1,   RadioS↑, 2,   selectivity↑, 6,  

Clinical Biomarkers ⓘ

AR↓, 3,   ascitic↓, 1,   FOXM1↓, 1,   hTERT/TERT↓, 1,   IL6↓, 2,   Ki-67↓, 4,   PSA↓, 6,  

Functional Outcomes ⓘ

AntiCan↑, 4,   AntiTum↑, 1,   hepatoP↑, 1,   neuroP↑, 1,   OS↑, 6,   QoL↑, 1,   Risk↓, 3,   TumVol↓, 48,   TumVol↑, 2,   TumW↓, 12,   Weight↑, 3,   Weight∅, 1,  
Total Targets: 221

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

Catalase↑, 2,   GPx↑, 1,   GSTs↑, 1,   HDL↑, 1,   ROS↓, 1,   SAM-e↑, 1,   SOD↑, 2,  

Mitochondria & Bioenergetics ⓘ

ATP↝, 1,  

Core Metabolism/Glycolysis ⓘ

NAD↝, 1,  

Cell Death ⓘ

MAPK↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

PTEN↑, 1,  

Migration ⓘ

5LO↓, 1,   Ca+2↝, 1,   serineP↓, 1,  

Angiogenesis & Vasculature ⓘ

VEGF↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   Inflam↓, 1,   NF-kB↓, 2,   PGE2↓, 1,   TNF-α↓, 1,   VitD↑, 2,  

Hormonal & Nuclear Receptors ⓘ

testos↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   Dose↑, 1,   Dose↝, 1,   eff↑, 2,   Half-Life↝, 1,   P450↓, 1,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

BMD↑, 1,   BMPs↑, 1,   Calcium↑, 2,   hs-CRP↓, 1,   Mag↑, 2,   VitD↑, 2,  

Functional Outcomes ⓘ

chemoP↑, 1,   chemoPv↑, 1,   ChemoSideEff↓, 1,   cognitive↑, 2,   memory↓, 1,   memory↑, 1,   motorD↓, 1,   neuroP↑, 1,   Risk↓, 1,   toxicity↓, 2,   toxicity↝, 3,  
Total Targets: 46

Scientific Paper Hit Count for: TumVol, Tumor Volume
15 Magnetic Fields
8 Silver-NanoParticles
8 Curcumin
7 Quercetin
7 Magnetic Field Rotating
6 doxorubicin
5 Apigenin (mainly Parsley)
5 Boron
4 EGCG (Epigallocatechin Gallate)
4 Hydrogen Gas
4 Shikonin
4 Thymoquinone
3 Vitamin C (Ascorbic Acid)
3 Ashwagandha(Withaferin A)
3 Betulinic acid
3 immunotherapy
3 metronomic chemo
3 Silymarin (Milk Thistle) silibinin
2 Gold NanoParticles
2 Allicin (mainly Garlic)
2 Baicalein
2 Berbamine
2 Berberine
2 Caffeic acid
2 Radiotherapy/Radiation
2 Cisplatin
2 Dichloroacetate
2 Orlistat
2 Honokiol
2 capecitabine
2 Naringin
2 Aflavin-3,3′-digallate
1 3-bromopyruvate
1 cetuximab
1 wortmannin
1 Ajoene (compound of Garlic)
1 Alpha-Lipoic-Acid
1 low dose naltrexone
1 Artemisinin
1 Brucea javanica
1 Bromelain
1 borneol
1 Vitamin D3
1 Boswellia (frankincense)
1 Caffeine
1 Zinc
1 Capsaicin
1 Cannabidiol
1 Chlorogenic acid
1 Chrysin
1 Photodynamic Therapy
1 Oxaliplatin
1 Metformin
1 Bortezomib
1 diet FMD Fasting Mimicking Diet
1 Chemotherapy
1 diet Methionine-Restricted Diet
1 Evodiamine
1 Docetaxel
1 Electrical Pulses
1 Fucoidan
1 Ferulic acid
1 Fenbendazole
1 Gallic acid
1 Garcinol
1 Graviola
1 HydroxyCitric Acid
1 Hyperthermia
1 Licorice
1 Lycopene
1 Melatonin
1 Bicarbonate(Sodium)
1 Phenylbutyrate
1 Piperine
1 probiotics
1 Pterostilbene
1 enzalutamide
1 Resveratrol
1 Rutin
1 salinomycin
1 Selenium
1 Oxygen, Hyperbaric
1 Sulforaphane (mainly Broccoli)
1 Iron
1 Salvia miltiorrhiza
1 Magnesium
1 Vitamin K2
1 Xylitol
1 Zerumbone
1 5-fluorouracil
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:530  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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