cognitive Cancer Research Results

cognitive, cognitive: Click to Expand ⟱
Source:
Type:
Cognitive


Scientific Papers found: Click to Expand⟱
4052- VitB6,    B-Vitamin Intake and Biomarker Status in Relation to Cognitive Decline in Healthy Older Adults in a 4-Year Follow-Up Study
- Study, AD, NA
*neuroP↑, *other↑, *other↑, *cognitive↑, *eff↝, *Risk↑, *other↑,
4077- VitB6,  FA,  VitB12,  VitD3,  VitE  Vitamin Supplementation as an Adjuvant Treatment for Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *cognitive↑, *Hcy/homoC↓, *Risk↓, *Risk↓, *Risk↓, *other↝, *Dose↝, *Risk↓, *Risk↓,
4065- VitB6,  VitB12,  FA,    Vitamin B6, B12, and Folic Acid Supplementation and Cognitive Function
- Review, AD, NA
*cognitive∅, *cognitive↑,
4319- VitC,    Unraveling the molecular mechanisms of vitamin deficiency in Alzheimer's disease pathophysiology
- Review, AD, NA
*ROS↓, *Inflam↓, *Risk↓, *cognitive↑,
3153- VitC,    Vitamin C Status and Cognitive Function: A Systematic Review
- Review, AD, NA
cognitive↑, eff↑,
4350- VitD3,    Vitamin D: Evidence-Based Health Benefits and Recommendations for Population Guidelines
- Review, Var, NA - Review, AD, NA
Risk↓, angioG↓, TumMeta↓, AntiCan↑, *cognitive↑, *Mood↑,
4320- VitD3,    Unraveling the molecular mechanisms of vitamin deficiency in Alzheimer's disease pathophysiology
- Review, AD, NA
*Calcium↝, *cognitive↑, *Aβ↓, *Inflam↓, *Risk↓, *other↝,
4086- VitD3,    The beneficial role of vitamin D in Alzheimer's disease
- Review, AD, NA
*Mood↑, *cognitive↑, *eff↑,
4184- VitD3,    Neuroplasticity-related effects of vitamin D relevant to its neuroprotective effects: A narrative review
- Review, AD, NA
*BDNF↑, *cognitive↑,
4182- VitD3,    The association between vitamin D and BDNF on cognition in older adults in Southern Brazil
- Study, AD, NA
*cognitive↑, *BDNF↑,
3921- VitD3,  RES,    Vitamin D Combined with Resveratrol Prevents Cognitive Decline in SAMP8 Mice
- in-vivo, AD, NA
*cognitive↑, *Aβ↓, *BACE/β-secretase↓, *p‑tau↓, *p‑CREB↑, *p‑NF-kB↓, *neuroP↑,
4089- VitE,    Cognitive function in elderly people is influenced by vitamin E status
- Study, AD, NA
*cognitive↑,
4088- VitE,    Vitamin E and Alzheimer’s Disease—Is It Time for Personalized Medicine?
- Review, AD, NA
*antiOx↑, *neuroP↑, *Dose↓, *cognitive↑, *other↝,
4087- VitE,    Vitamin E and Alzheimer's disease: what do we know so far?
- Review, AD, NA
*Risk↑, *Half-Life↑, *antiOx↑, *BioAv↑, *neuroP↑, *Inflam↑, *LDL↓, *cognitive↑,
4079- VitE,  VitC,    Effects of fruits and vegetables on levels of vitamins E and C in the brain and their association with cognitive performance
- Review, AD, NA
*neuroP↑, *antiOx↑, *Dose↝, *cognitive↑,
4321- VitE,    Unraveling the molecular mechanisms of vitamin deficiency in Alzheimer's disease pathophysiology
- Review, AD, NA
*ROS↓, *cardioP↑, *lipid-P↓, *cognitive↑, *neuroP↑, *Aβ↓, *NGF↑,
4322- VitK2,    Unraveling the molecular mechanisms of vitamin deficiency in Alzheimer's disease pathophysiology
- Review, AD, NA
*memory↑, *cognitive↑, *Inflam↓, *Calcium↝, *Aβ↓, *ROS↓, *neuroP↑,
4309- VitK2,    Vitamins in the Prevention and Support Therapy of Neurodegenerative Diseases
- Review, AD, NA
*Apoptosis↓, *ROS↓, *antiOx↑, *cognitive↑, *memory↑, *Risk↓, *p‑tau↓,
4188- VitK2,    Vitamin K2 protects against aluminium chloride-mediated neurodegeneration
- in-vivo, AD, NA
*BDNF↑, *Aβ↓, *cognitive↑, *Ach↑, *Inflam↓,
4091- VitK2,    The possible role of vitamin K deficiency in the pathogenesis of Alzheimer's disease and in augmenting brain damage associated with cardiovascular disease
- Review, AD, NA
*cognitive↑, *other↓, *cardioP↑,
4090- VitK2,  ProBio,    Vitamin K2 Holds Promise for Alzheimer's Prevention and Treatment
- Review, AD, NA
*antiOx↑, *Inflam↓, *Aβ↓, *memory↑, *NF-kB↓, *ROS↓, *GSH↑, *ATP↑, *p‑tau↓, *cardioP↑, *other↝, *cognitive↑,
7915- VT,    A Brief Review on the Neuroprotective Mechanisms of Vitexin
- Review, AD, NA - Review, Park, NA
*neuroP↑, *Inflam↓, *cognitive↓, *motorD↑, *BACE/β-secretase↓, *LDH↓, *AChE↓, *BChE↓, *ROS↓,
4084- Z,    Role of micronutrients in Alzheimer's disease: Review of available evidence
- Review, AD, NA
*neuroP↑, *cognitive↑, *AChE↓, *memory↑,
4191- Zeax,  Lut,    Effects of macular xanthophyll supplementation on brain-derived neurotrophic factor, pro-inflammatory cytokines, and cognitive performance
- Trial, AD, NA
*BDNF↑, *IL1β↓, *cognitive↑, *memory↑,

Showing Research Papers: 651 to 674 of 674
Prev Page 14 of 14

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 674

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 1,   GPx4↓, 1,   GSH↓, 5,   GSTs↑, 2,   H2O2↑, 2,   HO-1↑, 4,   Iron↑, 1,   lipid-P↓, 1,   lipid-P↑, 2,   MDA↑, 1,   NOX↓, 1,   NOX4↓, 1,   NQO1↑, 2,   NRF2↓, 1,   NRF2↑, 3,   RNS↓, 1,   ROS↓, 8,   ROS↑, 13,   ROS⇅, 1,   i-ROS↑, 1,   mt-ROS↑, 1,   SOD↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↓, 1,   mtDam↑, 1,   OXPHOS↓, 2,   OXPHOS↑, 1,   mt-OXPHOS↑, 1,   PDH↑, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 1,   AMPK↑, 1,   CRM↑, 1,   GlucoseCon↓, 1,   Glycolysis↓, 3,   Glycolysis↝, 1,   GSK‐3β↑, 1,   p‑GSK‐3β↓, 1,   HK2↓, 2,   lactateProd↓, 2,   LDL↓, 1,   NAD↑, 1,   NADPH↓, 2,   SCD1↓, 1,   SIRT1↑, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 1,   APAF1↑, 1,   Apoptosis↑, 20,   BAX↑, 7,   Bax:Bcl2↑, 1,   Bcl-2↓, 6,   BNIP3↑, 1,   Casp↑, 4,   Casp12↑, 1,   Casp3↓, 1,   Casp3↑, 7,   Casp8↑, 3,   Casp9↑, 5,   Cyt‑c↑, 7,   mt-Cyt‑c↓, 1,   DR5↑, 1,   Fas↑, 1,   Ferroptosis↑, 1,   GranB/GZMB↝, 1,   IAP1↓, 1,   IAP2/BIRC3↓, 1,   Mcl-1↓, 1,   p38↓, 1,   p38↑, 2,   Perforin↝, 1,   survivin↓, 1,   TumCD↓, 1,   TumCD↑, 2,   XIAP↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 7,   Akt↑, 2,   p‑Akt↓, 1,   EGFR↓, 3,   ERK↓, 5,   JAK2↓, 2,   JNK↑, 1,   MAPK↓, 2,   MAPK↑, 1,   mTOR↓, 3,   P70S6K↓, 1,   PI3K↓, 7,   p‑PI3K↓, 1,   PKCδ↓, 1,   PTEN↑, 1,   SHP1↑, 1,   Sp1/3/4↓, 2,   STAT3↓, 6,   p‑STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   ATF4↑, 2,   cMyc↓, 3,   cMyc↑, 1,   DNMT1↓, 1,   EZH2↓, 2,   FOXO1↓, 1,   FOXO1↑, 1,   FOXO3↓, 1,   FOXO4↓, 1,   HDAC↓, 2,   HDAC1↓, 1,   miR-124-3p↓, 1,   miR-21↓, 1,   miR-27a-3p↓, 1,   OCT4↓, 1,   other?, 1,   other↓, 1,   other↑, 3,   other↝, 3,   other∅, 1,   PAX2↓, 1,   SOX2↓, 1,   SOX9?, 1,   tumCV?, 1,   tumCV↓, 2,   ZBTB10↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   eIF2α↑, 1,   ER Stress↑, 3,   HSP70/HSPA5↓, 1,   PERK↓, 1,   PERK↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1/ATG6↑, 1,   LC3B-II↑, 1,   LC3II↓, 1,   LC3II↑, 1,   TumAuto↑, 5,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 5,   hTERT/TERT↓, 1,   p16↑, 1,   P53↓, 1,   P53↑, 5,   PARP↑, 1,   cl‑PARP↑, 2,   PCNA↓, 1,   Telomerase↓, 1,   TOP1↓, 1,   TP53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 4,   CDK6↑, 1,   CHK1↓, 1,   Cyc↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 8,   cycE/CCNE↑, 1,   Ki-67↓, 1,   mitA↑, 1,   P21↑, 3,   p27/CDKN1B↑, 1,   TumCCA↑, 17,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CSCs↓, 1,   EIF4E↓, 1,   IGF-1↓, 3,   Ki-67↓, 1,   Let-7↑, 1,   Nanog↓, 1,   NOTCH1↓, 1,   NOTCH1↑, 1,   TumCG↓, 11,   TumCG⇅, 1,   TumCP↓, 15,   Wnt↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   AP-1↓, 1,   BACH1↓, 1,   Ca+2↑, 3,   Cofilin↓, 1,   E-cadherin↓, 2,   E-cadherin↑, 1,   EMT↓, 4,   p‑FAK↓, 1,   LAMs↓, 2,   LIMK2↓, 1,   MALAT1↓, 1,   MMP1↓, 1,   MMP2↓, 5,   MMP9↓, 9,   MMPs↓, 2,   N-cadherin↓, 2,   ROCK1↓, 1,   serineP↓, 1,   TET1↑, 1,   TGF-β↓, 2,   TIMP2↑, 1,   TumCI↓, 5,   TumCMig↓, 9,   TumMeta↓, 7,   TumMeta↑, 1,   Twist↓, 1,   Vim↓, 1,   α-SMA↓, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 7,   HIF-1↓, 1,   Hif1a↓, 7,   VEGF↓, 12,   VEGFR2/KDR/Flk1↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   MMP↓, 5,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD47↓, 1,   CD8+↑, 2,   COX2/PTGS2↓, 6,   CXCL12↓, 1,   CXCR4↓, 2,   FOXP3↑, 1,   HMGB1↓, 1,   IL1↓, 1,   IL1β↓, 3,   IL2↓, 1,   IL4↓, 1,   IL6↓, 4,   IL8↓, 1,   Imm↑, 2,   Inflam↓, 4,   Inflam↑, 1,   MyD88↓, 1,   NF-kB↓, 14,   NK cell↑, 1,   PD-1↓, 1,   PD-L1↓, 3,   PGD2↓, 1,   PGE2↓, 2,   PSA↓, 3,   TLR4↓, 1,   TNF-α↓, 2,   TRIF↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BDNF↓, 1,   TrkB↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   p‑tau↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   ER(estro)↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 4,   BioAv↝, 4,   BioEnh↑, 1,   ChemoSen↑, 21,   CYP1A1↓, 1,   DDS↑, 1,   Dose↓, 1,   Dose↑, 2,   Dose↝, 6,   eff↓, 2,   eff↑, 11,   eff∅, 1,   Half-Life↑, 1,   MDR1↓, 1,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 2,   RadioS↑, 4,   selectivity↑, 4,   Synergy↑, 7,   Synergy↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   BMD↑, 1,   BP↓, 1,   EGFR↓, 3,   EZH2↓, 2,   hTERT/TERT↓, 1,   IL6↓, 4,   PD-L1↓, 3,   PSA↓, 3,   TP53↑, 1,   Verbal↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 2,   AntiCan↑, 13,   AntiTum↑, 3,   Appetite↑, 1,   cachexia↓, 1,   cardioP↑, 3,   chemoP↑, 9,   ChemoSideEff↓, 1,   cognitive?, 1,   cognitive↑, 20,   cognitive∅, 1,   hepatoP↑, 2,   memory↑, 9,   neuroP↑, 3,   NP/CIPN↓, 2,   OS↑, 3,   OS∅, 1,   Pain↓, 1,   PFS↑, 1,   PFS∅, 1,   QoL↑, 4,   radioP↑, 5,   Remission↑, 1,   RenoP↑, 1,   Risk↓, 8,   Risk↑, 1,   Risk⇅, 1,   Sleep↑, 1,   toxicity↓, 1,   TumVol↓, 6,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   GutMicro↑, 2,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,   Ingr↝, 1,  
Total Targets: 311

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,   NA↝, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

3-NT↓, 1,   4-HNE↓, 3,   antiOx?, 1,   antiOx↓, 6,   antiOx↑, 155,   mt-antiOx↑, 1,   ARE↑, 5,   Bil↑, 1,   Catalase↓, 2,   Catalase↑, 56,   Copper↓, 1,   Fenton↓, 1,   GCLC↑, 1,   GCLM↑, 1,   GPx↓, 1,   GPx↑, 36,   GPx1↑, 2,   GPx4↑, 3,   GSH↑, 69,   GSR↓, 2,   GSR↑, 7,   GSSG↓, 1,   GSTs↓, 1,   GSTs↑, 8,   H2O2↓, 5,   H2O2∅, 1,   HDL↑, 5,   HNE↓, 1,   HNE↑, 1,   HO-1↓, 2,   HO-1↑, 45,   HO-2↓, 1,   hyperG↝, 1,   Iron↓, 3,   Keap1↓, 1,   Keap1↝, 1,   lipid-P↓, 66,   MDA↓, 55,   MDA↑, 2,   MPO↓, 5,   MPOD↑, 3,   NADH↓, 1,   NOX↓, 3,   NQO1↑, 13,   Nrf1↑, 1,   NRF2↓, 4,   NRF2↑, 81,   Prx↓, 1,   Prx↑, 1,   RNS↓, 4,   ROS?, 1,   ROS↓, 230,   ROS↑, 3,   mt-ROS?, 1,   mt-ROS↓, 4,   SAM-e↓, 2,   SAM-e↑, 1,   SOD↓, 2,   SOD↑, 83,   SOD1↑, 4,   SOD2↑, 2,   TAC↑, 9,   TBARS↓, 5,   Thiols↑, 2,   TOS↓, 1,   Trx↑, 1,   Trx1↑, 1,   TrxR↑, 2,   VitC↑, 6,   VitE↑, 3,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↑, 1,   FTL↓, 1,   IronCh↑, 17,   TfR1/CD71↓, 3,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,   compII↑, 1,   compIII↑, 1,   compIV↑, 2,   DRP1/DNM1L↓, 1,   p‑DRP1/DNM1L↝, 1,   ETC↑, 1,   FIS1↓, 2,   HSP60/HSPD1↓, 1,   Insulin↓, 1,   Insulin↑, 2,   MFN1↝, 1,   MFN2↑, 1,   MFN2↝, 1,   mitResp↑, 3,   mtDam↓, 13,   mtDam↑, 1,   OCR↑, 3,   OXPHOS↑, 1,   PDH↑, 1,   PGC-1α↑, 10,   PGC-1α↝, 1,   SIRT3↑, 4,   TFAM↑, 2,   VDAC1↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 2,   5LO↓, 8,   ACC↓, 1,   ACC↑, 1,   Acetyl-CoA↑, 3,   AcOH↑, 1,   adiP↓, 1,   adiP↑, 3,   ALAT?, 1,   ALAT↓, 11,   ALAT∅, 1,   AMPK↑, 18,   p‑AMPK↑, 2,   ATP↑, 22,   ATP↝, 1,   Buty↑, 1,   cAMP↑, 3,   DHA↑, 2,   ECAR↓, 1,   FABP4↓, 1,   FAO↓, 1,   FASN↓, 1,   G6PD↑, 1,   glucose↓, 6,   glucose↑, 1,   GlucoseCon↑, 12,   GlutMet↑, 1,   Glycolysis↓, 2,   Glycolysis↑, 1,   GSK‐3β↓, 22,   GSK‐3β↑, 4,   GSK‐3β↝, 1,   p‑GSK‐3β↓, 1,   p‑GSK‐3β↑, 3,   H2S↑, 3,   HK2↑, 1,   KeyT↑, 5,   LDL↓, 18,   lipidLev↓, 1,   NAD↑, 2,   NAD↝, 1,   NADPH↓, 3,   NADPH↑, 3,   PDKs↓, 1,   PFK↓, 1,   PFK↑, 1,   PKM2↑, 1,   PONs↑, 1,   SCFAs↑, 1,   SIRT1↑, 17,   SIRT1∅, 1,   SREBF2⇅, 1,   SREBP1/SREBF1↓, 2,  

Cell Death(tgid=5) ⓘ

AIF↓, 2,   APAF1↓, 1,   Apoptosis↓, 35,   BAD↓, 1,   BAX↓, 11,   BAX↑, 1,   Bax:Bcl2↓, 5,   Bcl-2↓, 1,   Bcl-2↑, 13,   Casp↓, 1,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 20,   Casp3↑, 1,   cl‑Casp3↓, 5,   Casp6↓, 1,   cl‑Casp8↓, 1,   Casp9↓, 7,   Casp9↑, 1,   cl‑Casp9↓, 1,   Cyt‑c↓, 2,   Cyt‑c↑, 1,   Fas↓, 1,   Ferroptosis↓, 4,   GranB/GZMB↓, 1,   iNOS↓, 32,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 4,   p38↑, 1,   p‑p38↓, 4,   RIP1↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 5,   Akt↑, 30,   p‑Akt↓, 4,   p‑Akt↑, 8,   AKT1↓, 1,   AMPKα↑, 1,   CREB↓, 1,   CREB↑, 16,   p‑CREB↑, 5,   ERK↓, 5,   ERK↑, 9,   p‑ERK↓, 1,   p‑ERK↑, 4,   HER2/EBBR2↓, 1,   p‑IKKα↓, 2,   IκB↓, 1,   p‑IκB↓, 1,   JNK↓, 11,   JNK↑, 1,   p‑JNK↓, 4,   LPAR1/EDG2↑, 1,   MAPK↓, 14,   MAPK↑, 5,   p‑MAPK↓, 1,   Mst1↓, 1,   mTOR↓, 9,   mTOR↑, 6,   p‑mTOR↓, 2,   p‑mTOR↑, 1,   P70S6K↓, 1,   PI3K↓, 4,   PI3K↑, 19,   p‑PI3K↓, 2,   PKA↑, 3,   PKCδ↓, 2,   PKCδ↑, 4,   p‑PKCδ↑, 1,   PP2A↑, 3,   PTEN↓, 4,   PTEN↑, 1,   p‑PTEN↓, 1,   PTP1B↓, 1,   RKIP↑, 1,   STAT↓, 1,   STAT3↓, 2,   p‑STAT3↓, 1,   STEP↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ac-histone H3↑, 1,   AntiThr↑, 1,   ATF4↓, 3,   ATF4↑, 1,   cJun↓, 1,   cMyc↓, 1,   DNMT1↓, 1,   DNMT3A↓, 1,   DNMT3A↑, 1,   FOXO↑, 1,   FOXO3↑, 3,   H3↑, 1,   H4↑, 1,   HATs↓, 1,   HDAC↓, 1,   HDAC↑, 2,   HDAC1↓, 2,   HDAC2↓, 2,   HDAC3↓, 2,   MEF2D↑, 1,   other?, 2,   other↓, 22,   other↑, 42,   other⇅, 1,   other↝, 46,   other∅, 2,   SOX2↑, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 5,   eIF2α↓, 2,   p‑eIF2α↓, 1,   ER Stress↓, 12,   ER Stress↑, 1,   GRP78/BiP↓, 6,   GRP78/BiP↑, 1,   HSF1↑, 2,   HSP70/HSPA5↑, 6,   HSP90↓, 1,   HSP90↑, 2,   HSPs↝, 1,   IRE1↓, 2,   PERK↓, 3,   p‑PERK↓, 1,   UPR↑, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   autophagy↓, 1,   autophagy↝, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 3,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3B↑, 2,   LC3II↓, 1,   LC3II↑, 2,   MitoP↑, 1,   p62↓, 1,   p62↑, 1,   PARK2↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 7,   DNArepair↑, 1,   p16↓, 1,   P53↓, 3,   PARP1↓, 1,   SIRT6↑, 1,   Telomerase↓, 1,   TOP1↓, 1,   TP53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK5↓, 4,   cellSen↝, 1,   cycD1/CCND1↓, 1,   Ki-67↓, 1,   Ki-67↑, 2,   P21↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMPs↑, 1,   CEBPA↓, 1,   cFos↑, 1,   Choline↑, 3,   Diff↑, 1,   EP2↑, 1,   FGF↑, 1,   GH↑, 1,   IGF-1↓, 1,   IGF-1↑, 1,   Jun↓, 1,   Ki-67↓, 1,   Ki-67↑, 2,   Nestin↑, 1,   neuroG↑, 10,   NOTCH1↑, 2,   TumCG↓, 1,   TumCP↓, 1,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 3,   AntiAg↑, 11,   AP-1↓, 5,   ARG1/2↑, 1,   Ca+2↓, 15,   Ca+2↑, 2,   Ca+2↝, 2,   cal2↓, 1,   Cartilage↑, 2,   FNDC5↑, 1,   LRP1↑, 3,   MMP-10↓, 1,   MMP-10↝, 1,   MMP1↓, 1,   MMP2↓, 2,   MMP2↑, 1,   MMP3↓, 2,   MMP9↓, 12,   MMPs↓, 2,   MUC1↑, 1,   N-cadherin↑, 2,   NFAT↓, 1,   ROCK1↓, 1,   serineP↓, 1,   p‑SMAD2↓, 1,   SPARC↓, 1,   p‑T-cadherin↓, 1,   TGF-β↓, 3,   TGF-β↑, 2,   TGF-β1↓, 1,   TGF-β1↑, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TumCI↓, 1,   TumMeta↓, 1,   TXNIP↓, 1,   uPA↑, 1,   Vim↓, 1,   β-catenin/ZEB1↑, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 2,   CD31/PECAM-1↑, 2,   Endoglin↑, 1,   eNOS↑, 1,   p‑eNOS↑, 2,   Hif1a↓, 1,   Hif1a↑, 1,   NO↓, 29,   NO↑, 4,   TXA2↓, 1,   VCAM-1↓, 8,   VEGF↓, 1,   VEGF↑, 7,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,   BBB?, 2,   BBB↓, 1,   BBB↑, 77,   BBB↝, 5,   BBB∅, 2,   CLDN1↓, 1,   GastroP↑, 3,   GLUT1↑, 2,   GLUT3↑, 2,   GLUT4↑, 5,   IBI↑, 4,   memfluid↑, 1,   MMP↑, 18,   MMP↝, 1,   TJ↓, 1,   TJ↑, 1,   TJ↝, 1,   TRPM7↓, 2,   TRPV1↑, 1,   TRPV3↑, 2,   ZO-1↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIF1/Iba-1↓, 2,   CD4+↑, 1,   COX1↓, 4,   COX2/PTGS2?, 1,   COX2/PTGS2↓, 45,   COX2/PTGS2↑, 1,   ICAM-1↓, 5,   IFN-γ↓, 2,   IFN-γ↑, 2,   IL1↓, 3,   IL10↓, 3,   IL10↑, 11,   IL12↓, 2,   IL18↓, 1,   IL1β↓, 59,   IL1β↑, 2,   IL2↓, 6,   IL22↓, 1,   IL33↓, 1,   IL4↓, 5,   IL4↑, 3,   IL6↓, 58,   IL6↑, 2,   IL8↓, 5,   Imm↑, 10,   Imm↝, 1,   INF-γ↓, 3,   Inflam?, 1,   Inflam↓, 217,   Inflam↑, 2,   Inflam∅, 1,   IRF3↓, 3,   LPS↓, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 6,   MCP1/CCL2↝, 1,   MIP‑1α/CCL3↓, 1,   MIP2↓, 1,   MyD88↓, 3,   NeuroI↓, 11,   NF-kB↓, 67,   NF-kB↑, 1,   p‑NF-kB↓, 4,   NK cell↑, 1,   NLRP3↓, 17,   NLRP3↑, 2,   p‑p65↓, 1,   PGE2↓, 15,   RAGE↓, 3,   RANTES↓, 1,   SOCS-3↓, 1,   TLR1↓, 1,   TLR2↓, 4,   TLR3↓, 1,   TLR4↓, 12,   TLR4↑, 1,   TNF-α↓, 92,   TRIF↓, 2,   VitD↑, 2,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 7,   TREM2↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 12,   Ach?, 1,   Ach↑, 31,   AChE↓, 87,   AChE↝, 2,   AChE∅, 4,   ADAM10↑, 7,   BChE↓, 14,   BDNF↓, 1,   BDNF↑, 90,   BDNF∅, 2,   proBDNF↑, 1,   BrainVol↑, 3,   BrainVol↝, 1,   BrainVol∅, 3,   ChAT↑, 15,   DA↑, 1,   GABA↓, 2,   GABA↑, 4,   MAOA↓, 6,   MAOA↝, 1,   MAOB↓, 4,   monoA↑, 1,   NGF↑, 11,   PSD95?, 1,   PSD95↑, 12,   RELN↑, 1,   SNAP25↑, 3,   SYN1↑, 1,   SYP↑, 2,   SYT1↑, 1,   TrkB↑, 9,   TrkB↝, 1,  

Protein Aggregation(tgid=19) ⓘ

AEP↓, 1,   AGEs↓, 4,   APOE4↓, 1,   APOE4↑, 1,   APP↓, 20,   APP↝, 1,   cl‑APP↑, 1,   Aβ?, 1,   Aβ↓, 176,   Aβ↑, 2,   Aβ∅, 4,   Aβ42↓, 8,   BACE/β-secretase↓, 43,   BACE/β-secretase↑, 2,   BACE/β-secretase↝, 1,   IDE↑, 3,   NEP↑, 1,   PSEN1/PS1↓, 2,   PSEN1/PS1↑, 1,   tau?, 1,   tau↓, 35,   p‑tau↓, 53,   β-Amyloid↓, 3,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AHR↓, 1,   AKR1C3/17β-HSD5/PGF Synthase↑, 1,   cortisol↓, 1,   END↑, 1,   ER(estro)↓, 1,   ER(estro)↑, 1,   ERβ/ESR2↑, 1,   FGF21↑, 2,   PPARα↑, 6,   PPARγ↓, 2,   PPARγ↑, 10,   RAAS↓, 1,   testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

AKR1B1/ALR2↑, 1,   AKR1B10↝, 1,   BioAv↓, 23,   BioAv↑, 57,   BioAv⇅, 1,   BioAv↝, 31,   BioEnh↑, 3,   ChemoSen↑, 3,   CompStab↑, 3,   CYP3A2↓, 2,   DDS↑, 1,   Dose?, 6,   Dose↓, 3,   Dose↑, 8,   Dose⇅, 1,   Dose↝, 128,   eff↓, 6,   eff↑, 68,   eff↝, 8,   eff∅, 1,   Half-Life?, 1,   Half-Life↓, 8,   Half-Life↑, 5,   Half-Life↝, 14,   P-gp/ABCB1↓, 1,   P450↓, 1,   P450↑, 1,   selectivity↑, 1,   Synergy↑, 32,  

Clinical Biomarkers(tgid=22) ⓘ

ADC↓, 1,   ALAT?, 1,   ALAT↓, 11,   ALAT∅, 1,   ALB↑, 1,   ALP↓, 1,   AST↓, 12,   AST∅, 1,   BG↓, 1,   Bil↑, 1,   BloodF↑, 6,   BMD↑, 4,   BP↓, 23,   BP↝, 1,   BP∅, 2,   Calcium↑, 3,   Calcium↝, 2,   creat↓, 3,   CRP↓, 8,   Ferritin↑, 1,   Hcy/homoC↓, 19,   Hcy/homoC↝, 2,   HemoG↑, 1,   HER2/EBBR2↓, 1,   HRV↑, 1,   hs-CRP↓, 1,   IL6↓, 58,   IL6↑, 2,   IRes↑, 1,   KeyT↑, 5,   LDH↓, 11,   LDH↑, 1,   Mag↑, 2,   NOS2↓, 2,   RAGE↓, 3,   rHR↓, 1,   TMAO↓, 1,   TMAO↑, 4,   TP53↑, 1,   Urea↓, 1,   VitD↑, 2,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   Anger↓, 1,   AntiAge↑, 11,   antiAll↑, 10,   AntiArt↑, 5,   AntiCan↑, 12,   antiCG↑, 1,   antiD↑, 1,   AntiDiabetic↑, 15,   AntiMyl↑, 1,   antiPs↑, 3,   AntiTum↑, 2,   ANXi↓, 1,   BOLD↑, 2,   cardioP↓, 1,   cardioP↑, 50,   chemoP↑, 6,   chemoPv↑, 3,   ChemoSideEff↓, 1,   cognitive?, 2,   cognitive↓, 16,   cognitive↑, 614,   cognitive↝, 9,   cognitive?, 1,   cognitive∅, 27,   cough?, 1,   fatigue↓, 1,   hepatoP↑, 28,   Learn?, 1,   Learn↑, 19,   memory?, 2,   memory↓, 2,   memory↑, 238,   memory∅, 4,   Mood?, 1,   Mood↑, 24,   Mood↝, 1,   motorD↓, 1,   motorD↑, 31,   neuroP?, 1,   neuroP↓, 1,   neuroP↑, 275,   neuroP↝, 1,   Obesity↓, 14,   OS↑, 11,   Pain↓, 6,   QoL?, 1,   QoL↑, 5,   QoL∅, 1,   radioP↑, 4,   RenoP↑, 8,   Risk↓, 38,   Risk↑, 6,   Risk↝, 1,   Risk∅, 1,   RT↓, 1,   Sleep↑, 13,   SoreThr?, 1,   Strength↑, 5,   Stress↓, 2,   Stroke↓, 19,   Stroke↑, 1,   Tinn↓, 1,   toxicity↓, 31,   toxicity↑, 3,   toxicity↝, 5,   toxicity∅, 9,   Weight↓, 3,   Weight↝, 1,   Weight∅, 1,   Wound Healing↑, 6,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 7,   AntiFungal↑, 4,   AntiViral↑, 7,   Bacteria↓, 5,   Diar↓, 2,   GutMicro↑, 29,   Inf↓, 1,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

CA↑, 1,   Catechins↑, 1,   FA↑, 1,   GA↑, 1,   Ingr↑, 1,   Ingr↝, 5,   Phen↑, 1,   QC↑, 1,  
Total Targets: 687

Scientific Paper Hit Count for: cognitive, cognitive
32 Folic Acid, Vit B9
30 Vitamin B12
24 Magnetic Fields
21 Hydrogen Gas
19 Alpha-Lipoic-Acid
15 Vitamin B6,pyridoxine
15 Curcumin
13 beta-carotene(VitA)
13 Lutein
13 Choline
13 Phosphatidylserine
12 Zeaxanthin
12 Urolithin
11 Exercise
11 Centella asiatica / Gotu kola → asiaticoside
11 Crocetin
11 Ginkgo biloba-EGb 761
11 MCT oil
11 Mushroom Lion’s Mane, Hericium erinaceus
11 Thymoquinone
10 Bacopa monnieri
10 Chlorogenic acid
10 Quercetin
9 Anthocyanins
9 Aromatherapy
9 Vitamin E
9 Resveratrol
9 Vitamin D3
8 Berberine
8 Lycopene
8 Selenium NanoParticles
8 Huperzine A/Huperzia serrata
8 Ferulic acid
8 Salvia officinalis
8 Ginseng
8 Rosmarinic acid
7 flavonoids
7 Ashwagandha(Withaferin A)
7 Mung Bean Sprouts
7 Silicic Acid
7 Magnetic Field Rotating
6 Allicin (mainly Garlic)
6 Gamma-aminobutyric acid
6 Ginkgo biloba
6 Luteolin
6 EMF
6 Sulforaphane (mainly Broccoli)
6 Silymarin (Milk Thistle) silibinin
5 5-Hydroxytryptophan
5 Vitamin C (Ascorbic Acid)
5 Aluminum
5 Vitamin B3,Niacin
5 Caffeic acid
5 Carvacrol
5 Carnosine
5 EGCG (Epigallocatechin Gallate)
5 HydroxyTyrosol
5 Magnesium
5 Melatonin
5 Moringa oleifera
5 Rutin
5 Taurine
5 Vitamin K2
4 Acetyl-l-carnitine
4 Docosahexaenoic Acid
4 Emodin
4 Lemon Balm/Melissa officinalis
4 Ginkgolide B
4 isoquercitrin
4 Licochalcone A
4 Methylene blue
4 Magnolol
4 Spermidine
4 Vitamin B1/Thiamine
3 Baicalein
3 Boron
3 Boswellia (frankincense)
3 Capsaicin
3 Chocolate
3 Cinnamon
3 Coenzyme Q10
3 Galantamine
3 diet Short Term Fasting
3 Flickering Light Stimulation
3 Shilajit/Fulvic Acid
3 Honokiol
3 Hormone replacement therapy
3 Oleuropein
3 Isoliquiritigenin
3 isoorientin
3 nicotinamide adenine dinucleotide
3 Piperine
3 Pterostilbene
3 Radio Frequency
2 Serotonin, 5-hydroxytryptamine
2 alpha Linolenic acid
2 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
2 Apigenin (mainly Parsley)
2 Artemisinin
2 Betulinic acid
2 Carnosic acid
2 Caffeine
2 chitosan
2 Lecithin
2 Chrysin
2 Chyawanprash
2 Ellagic acid
2 Protocatechuic acid
2 Angelica archangelica / Garden Angelica
2 Fisetin
2 Bifidobacterium animalis subsp. lactis GCL2505
2 Radiotherapy/Radiation
2 isoflavones
2 Potassium
2 Kaempferol
2 Licorice
2 Lactoferrin/Talactoferrin
2 Matrine
2 Metformin
2 Marjoram (Origanum majorana)
2 Propolis -bee glue
2 Phenolic Acids
2 Shikonin
2 Ursolic acid
1 dietMediterranean
1 Baicalin
1 Beta-Caryophyllene
1 borneol
1 α-Bisabolol / Chamomile oil
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Cichoric acid / Chicoric acid
1 Rivastigmine
1 Date Fruit Extract
1 diet Fermented Foods
1 diet Methionine-Restricted Diet
1 Diindolylmethane
1 Indole-3-carbinol
1 Eurycomanone
1 Auditory Gamma Stimulation / 40 Hz Auditory Stimulation
1 Formononetin
1 Genistein (soy isoflavone)
1 Graviola
1 hydrogen sulfide
1 Helleborus niger extracts – Christmas Rose
1 Isobavachalcone
1 Inulin Prebiotic
1 Isovitexin
1 SDG/lignans
1 Linalool
1 Silver-NanoParticles
1 Morin
1 Myricetin
1 Naringin
1 Olive Oil
1 Phenylbutyrate
1 Hydroxycinnamic-acid
1 Piperlongumine
1 Sinapic acid
1 S-adenosyl-L-methionine
1 Selenium
1 Sesame seeds and Oil
1 Shankhpushpi
1 Chemotherapy
1 Thymol-Thymus vulgaris
1 Vitamin A, Retinoic Acid
1 probiotics
1 Vitexin
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:557  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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