antiOx Cancer Research Results

antiOx, anti-oxidant activities: Click to Expand ⟱
Source:
Type:
Various antioxidants such as Nrf2, SODs, catalase, GPxs, PRDXs, and GSTs are altered in different cancers and have been linked to prognosis. Their overexpression can correlate with aggressive tumor behavior and resistance to treatment in many contexts.
Scientific Papers found: Click to Expand⟱
3040- SK,    Pharmacological Properties of Shikonin – A Review of Literature since 2002
- Review, Var, NA - Review, IBD, NA - Review, Stroke, NA
*Half-Life↝, *BioAv↓, *BioAv↑, *BioAv↑, *Inflam↓, *TNF-α↓, *other↑, *MPO↓, *COX2/PTGS2↓, *NF-kB↑, *STAT3↑, *antiOx↑, *ROS↓, *neuroP↑, *SOD↑, *Catalase↑, *GPx↑, *Bcl-2↑, *BAX↓, cardioP↑, AntiCan↑, NF-kB↓, ROS↑, PKM2↓, TumCCA↑, Necroptosis↑, Apoptosis↑, DNAdam↑, MMP↓, Cyt‑c↑, LDH↝,
4891- Sper,    Spermidine as a promising anticancer agent: Recent advances and newer insights on its molecular mechanisms
- Review, Var, NA - Review, AD, NA
TumCCA↑, TumCP↓, TumCG↓, *Inflam↓, *antiOx↑, *neuroP↑, *cognitive↑, *Aβ↓, *mitResp↑, AntiCan↑, TumCD↑, TumAuto↑, *AntiAge↑, LC3B-II↑, ATG5↑, Beclin-1↑, mt-ROS↑, H2O2↑, Apoptosis↑, *ROS↑, ChemoSen↑, MMP↓, Cyt‑c↑,
4727- SSE,    Selenium inhibits ferroptosis in ulcerative colitis through the induction of Nrf2/Gpx4
- in-vivo, Col, NA
*Ferroptosis↓, *NRF2↑, *GPx4↑, *eff↑, *other↓, *antiOx↑, *Inflam↓, AntiTum↑,
4742- SSE,    Antitumor Effects of Selenium
- Review, Var, NA - Review, Arthritis, NA - Review, Sepsis, NA
*antiOx↓, *Inflam↓, Risk↓, TumCI↓, TumMeta↓, radioP↑, chemoP↑, Apoptosis↑, ROS↑, DNAdam↑, Dose↑, selectivity↑, *other↓, *BioAv↑, ROS↑, MMP↓, Casp↑, *Imm↑, *Pain↓, Sepsis↓, MMP2↓, MMP9↓, *Half-Life↓,
5082- SSE,    Rationale for the treatment of cancer with sodium selenite
- Review, Var, NA
Risk↑, antiOx↑, ROS↑, Imm↑, NK cell↑, angioG↓, toxicity↓,
5092- SSE,    Redox-Active Selenium Compounds—From Toxicity and Cell Death to Cancer Treatment
- Review, Var, NA
*antiOx↑, ROS↑, GSH↓, BioAv↓,
4610- SSE,  Rad,    Protection during radiotherapy: selenium
- Review, Var, NA
*radioP↑, *antiOx↑, *Inflam↓, *DNAdam↓, *lipid-P↓, *selenoP↑, *GPx1↑, *BUN↓,
6433- T4O,  CET,    Terpinen-4-ol: A Novel and Promising Therapeutic Agent for Human Gastrointestinal Cancers
- in-vitro, Colon, HT29 - in-vitro, CRC, HCT116 - in-vitro, PC, COLO357 - Human, Colon, NA
TumCG↓, eff↑, ChemoSen↑, Apoptosis↑, TumVol↓, TumW↓, *Inflam↓, *antiOx↓, BioAv↝,
4151- Taur,  Gins,    Taurine and Ginsenoside Rf Induce BDNF Expression in SH-SY5Y Cells: A Potential Role of BDNF in Corticosterone-Triggered Cellular Damage
- in-vitro, AD, NA
*BDNF↑, *antiOx↑, *neuroP↑, *eff↑,
3957- Taur,    Expedition into Taurine Biology: Structural Insights and Therapeutic Perspective of Taurine in Neurodegenerative Diseases
*UPR↑, *Inflam↓, *antiOx↑, *ROS↓, *Apoptosis↓, *Ca+2↓, *neuroP↑,
3952- Taur,    Taurine and Astrocytes: A Homeostatic and Neuroprotective Relationship
- Review, AD, NA - Review, Stroke, NA
*antiOx↑, *Inflam↓, *Ca+2↓, *neuroP↑, *other↑, *Dose↝, *PKCδ↓, *VGCC↓, *GABA↑,
5338- TFdiG,    Isolation and antioxidant characterization of theaflavin for neuroprotective effect in mice model
- in-vivo, Nor, NA
*antiOx↑, *TOS↑, *TAC↑, *neuroP↑,
1937- TQ,    Migration and Proliferation Effects of Thymoquinone-Loaded Nanostructured Lipid Carrier (TQ-NLC) and Thymoquinone (TQ) on In Vitro Wound Healing Models
- NA, Nor, 3T3
*ROS↓, *antiOx↓, *BioAv↓, *BioAv↑, *NO↑, *SOD↑, *GPx↑, *Catalase↑,
1930- TQ,    Therapeutic implications and clinical manifestations of thymoquinone
- Review, Var, NA
AntiCan↑, antiOx↑, Inflam↓, TumCP↓, TumCCA↑, Apoptosis↑, ROS↑, TumMeta↓, TumCI↓,
1933- TQ,    Thymoquinone: potential cure for inflammatory disorders and cancer
- Review, Var, NA
antiOx↑, Inflam↓, AntiCan↑, TumCCA↑, ROS↑, angioG↓, Apoptosis↑, Casp↑, eff↑, eff↝,
2116- TQ,  Cisplatin,    Oral administration of Nigella sativa oil ameliorates the effect of cisplatin on membrane enzymes, carbohydrate metabolism and oxidative damage in rat liver
- in-vivo, Nor, NA
*hepatoP↑, *antiOx↑, *ROS↓, ALAT↓, AST↓,
2114- TQ,    Anti-Aging Effect of Nigella Sativa Fixed Oil on D-Galactose-Induced Aging in Mice
- in-vivo, Nor, NA
*ALAT↓, *AST↓, *lipid-P↓, *GSH↑, *Bax:Bcl2↓, *proCasp3↓, *cl‑Casp3↓, *antiOx↑,
2113- TQ,    Potential role of Nigella sativa (NS) in abating oxidative stress-induced toxicity in rats: a possible protection mechanism
- in-vivo, Nor, NA
*antiOx↑, *RenoP↑, *hepatoP↑, *SOD↑, *GSH↑, *ROS↓, *lipid-P↓, ALAT↓, creat↓,
2126- TQ,    Biological and therapeutic activities of thymoquinone: Focus on the Nrf2 signaling pathway
- Review, Nor, NA
*antiOx↑, *Bacteria↓, *RenoP↑, *hepatoP↑, *neuroP↑, *Inflam↓, *Keap1↓, *NRF2↑, *other↝,
2128- TQ,    Thymoquinone inhibits phorbol ester-induced activation of NF-κB and expression of COX-2, and induces expression of cytoprotective enzymes in mouse skin in vivo
- in-vivo, NA, NA
*COX2/PTGS2↓, *NF-kB↓, *p‑Akt↓, *p‑cJun↓, *p‑p38↓, *HO-1↑, *NADPH↑, *GSTA1↑, *antiOx↑, *Inflam↓, *NQO1↑, *GCLC↑, *GSTA1↑,
2132- TQ,    Thymoquinone treatment modulates the Nrf2/HO-1 signaling pathway and abrogates the inflammatory response in an animal model of lung fibrosis
- in-vivo, Nor, NA
*Weight∅, *antiOx↑, *lipid-P↓, *MMP7↓, *Casp3↓, *BAX↓, *TGF-β↓, *Diff↑, *NRF2↓, *HO-1↓, *NF-kB↓, *IκB↑,
2087- TQ,    Nigella sativa thymoquinone-rich fraction greatly improves plasma antioxidant capacity and expression of antioxidant genes in hypercholesterolemic rats
- in-vivo, Nor, NA
*LDL↓, *SOD1↑, *Catalase↑, *GPx↑, *antiOx↑,
2100- TQ,    Dual properties of Nigella Sative: Anti-oxidant and Pro-oxidant
- Review, NA, NA
ROS⇅, *antiOx↑, *SOD↑, *MPO↑, *neuroP↑, *chemoP↑, *radioP↑, NF-kB↓, IAP1↓, IAP2/BIRC3↓, XIAP↓, Bcl-xL↓, survivin↓, COX2/PTGS2↓, MMP9↓, VEGF↓, ROS↑, P21↑, HDAC↓, GSH↓, GADD45A↑, AIF↑, STAT3↓,
4538- TQ,    Thymoquinone Anticancer Effects Through the Upregulation of NRF2 and the Downregulation of PD‐L1 in MDA‐MB‐231 Triple‐Negative Breast Cancer Cells
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
antiOx↑, H2O2↓, Catalase↑, SOD↑, GSH↑, PRNP↑, NQO1↑, GCLM↑, NRF2↑, PD-L1↓, chemoPv↑, ROS↓,
5024- TQ,    Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients?
- Review, Covid, NA
*NRF2↑, *NF-kB↓, *Inflam↓, *ROS↓, *HO-1↑, antiOx↑, GSH↑, GSTs↑, GSR↑, SOD1↑, Catalase↑, GPx↑, p62↓, Beclin-1↑, Sepsis↓, cardioP↑, hepatoP↑, neuroP↑,
3554- TQ,    Neuroprotective efficacy of thymoquinone against amyloid beta-induced neurotoxicity in human induced pluripotent stem cell-derived cholinergic neurons
- in-vitro, AD, NA
*GSH↑, *ROS↓, *neuroP↑, *Casp3↓, *Casp7↓, *antiOx↓, *H2O2↓,
3557- TQ,    Thymoquinone protects against lipopolysaccharides-induced neurodegeneration and Alzheimer-like model in mice.
- in-vivo, AD, NA
*Inflam↓, *antiOx↑, *cognitive↑, *TNF-α↓, *IL1β↓, *AChE↓, *IL10↑, *ChAT↑, *Aβ↓,
3559- TQ,    Molecular signaling pathway targeted therapeutic potential of thymoquinone in Alzheimer’s disease
- Review, AD, NA - Review, Var, NA
*antiOx↑, *Inflam↓, *AChE↓, AntiCan↑, *cardioP↑, *RenoP↑, *neuroP↑, *hepatoP↑, TumCG↓, Apoptosis↑, PI3K↓, Akt↑, TumCCA↑, angioG↓, *NF-kB↓, *TLR2↓, *TLR4↓, *MyD88↓, *TRIF↓, *IRF3↓, *IL1β↓, *IL6↓, *IL12↓, *NRF2↑, *COX2/PTGS2↓, *VEGF↓, *MMP9↓, *cMyc↓, *cycD1/CCND1↓, *TumCP↓, *TumCI↓, *MDA↓, *TGF-β↓, *CRP↓, *Casp3↓, *GSH↑, *IL10↑, *iNOS↑, *lipid-P↓, *SOD↑, *H2O2↓, *ROS↓, *LDH↓, *Catalase↑, *GPx↑, *AChE↓, *cognitive↑, *MAPK↑, *JNK↑, *BAX↓, *memory↑, *Aβ↓, *MMP↑,
3553- TQ,    Study Effectiveness and Stability Formulation Nanoemulsion of Black Cumin Seed (Nigella sativa L.) Essential Oil: A Review
- Review, Nor, NA
*AntiCan↑, *Inflam↓, *antiOx↑, *AntiAge↑, *hepatoP↑, *cardioP↑, *neuroP↑, *eff↑,
3564- TQ,    The Potential Neuroprotective Effect of Thymoquinone on Scopolamine-Induced In Vivo Alzheimer's Disease-like Condition: Mechanistic Insights
- in-vivo, AD, NA
*Inflam↓, *AntiCan↑, *antiOx↑, *neuroP↑, *cognitive↑, *Aβ↓, *PPARγ↑, *NF-kB↓, *p‑tau↓, *MMP↑, *memory↑, *NF-kB↓, *ROS↓,
3571- TQ,    The Role of Thymoquinone in Inflammatory Response in Chronic Diseases
- Review, Var, NA - Review, Stroke, NA
*BioAv↓, *BioAv↑, *Inflam↓, *antiOx↑, *ROS↓, *GSH↑, *GSTs↑, *MPO↓, *NF-kB↓, *COX2/PTGS2↓, *IL1β↓, *TNF-α↓, *IFN-γ↓, *IL6↓, *cardioP↑, *lipid-P↓, *TAC↑, *RenoP↑, Apoptosis↑, TumCCA↑, TumCP↓, TumCMig↓, angioG↓, TNF-α↓, NF-kB↓, ROS↑, EMT↓, *Aβ↓, *p‑tau↓, *BACE/β-secretase↓, *TLR2↓, *TLR4↓, *MyD88↓, *IRF3↓, *eff↑, eff↑, DNAdam↑, *iNOS↓,
3410- TQ,    Anti-inflammatory effects of thymoquinone and its protective effects against several diseases
- Review, Arthritis, NA
*Inflam↓, *antiOx↑, *COX2/PTGS2↓, *NRF2↑, *HO-1↑, *IL1β↓, *IL6↓, *TNF-α↓, *IFN-γ↓, *PGE2↓, *cardioP↑, *Catalase↑, *SOD↑, *Thiols↑, *neuroP↑, *IL12↓, *MCP1/CCL2↓, *CXCc↓, *ROS↓,
3408- TQ,    Thymoquinone: A small molecule from nature with high therapeutic potential
- Review, AD, NA - Review, Park, NA
*neuroP↑, *hepatoP↑, *cardioP↑, *Inflam↓, *antiOx↑, ChemoSen↑, eff↑, eff↑, TumCP↓, TumCCA↑, angioG↓, cycA1/CCNA1↓, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓,
3407- TQ,    Thymoquinone and its pharmacological perspective: A review
- Review, NA, NA
*antiOx↑, *ROS↓, *GSTs↑, *GSR↑, *GSH↑, *RenoP↑, *IL1β↓, *TNF-α↓, *MMP13↓, *COX2/PTGS2↓, *PGE2↓, *radioP↑, Twist↓, EMT↓, NF-kB↓, p‑PI3K↓, p‑Akt↓, p‑GSK‐3β↓, DNMT1↓, HDAC↓,
3401- TQ,    Molecular mechanisms and signaling pathways of black cumin (Nigella sativa) and its active constituent, thymoquinone: a review
- Review, Var, NA
TumCP↓, *antiOx↑, *ROS↓, NRF2↑, NF-kB↓, TumCCA↑, *GABA↑, P53↑, P21↑, AMPK↑, neuroP↑, cardioP↑, hepatoP↑,
3397- TQ,    Thymoquinone: A Promising Therapeutic Agent for the Treatment of Colorectal Cancer
- Review, CRC, NA
ChemoSen↑, *Half-Life↝, *BioAv↝, *antiOx↑, *Inflam↓, *hepatoP↑, TumCP↓, TumCCA↑, Apoptosis↑, angioG↑, selectivity↑, JNK↑, p38↑, p‑NF-kB↑, ERK↓, PI3K↓, PTEN↑, Akt↓, mTOR↓, EMT↓, Twist↓, E-cadherin↓, ROS⇅, *Catalase↑, *SOD↑, *GSTA1↑, *GPx↑, *PGE2↓, *IL1β↓, *COX2/PTGS2↓, *MMP13↓, MMPs↓, TumMeta↓, VEGF↓, STAT3↓, BAX↑, Bcl-2↑, Casp9↑, Casp7↑, Casp3↑, cl‑PARP↑, survivin↓, cMyc↓, cycD1/CCND1↓, p27/CDKN1B↑, P21↑, GSK‐3β↓, β-catenin/ZEB1↓, chemoP↑,
3432- TQ,    Thymoquinone: Review of Its Potential in the Treatment of Neurological Diseases
- Review, AD, NA - Review, Park, NA
*memory↑, *cognitive↑, *ROS↓, *Inflam↓, *antiOx↑, *TLR1↓, *AChE↓, *MMP↑, *neuroP↑, *lipid-P↓, *SOD↑, *GSH↑, *Ach↑,
3415- TQ,    The anti-neoplastic impact of thymoquinone from Nigella sativa on small cell lung cancer: In vitro and in vivo investigations
- in-vitro, Lung, H446
tumCV↓, TumCCA↑, ROS↓, CycB/CCNB1↑, CycD3↑, cycA1/CCNA1↓, cycE/CCNE↓, cDC2↓, antiOx↑, PARP↓, NRF2↓, ARE/EpRE↑, eff↑,
5904- TV,    Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Obesity, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *Inflam↓, *Bacteria↓, AntiTum↑, IronCh↑, *HDL↑, *LDL↓, *BioAv↝, *Half-Life↝, *BioAv↑, *SOD↑, *GPx↑, *GSTs↑, *eff↑, radioP↑, *MDA↓, *other↑, *COX1↓, *COX2/PTGS2↓, *AntiAg↑, *RNS↓, *NO↓, *H2O2↓, *NOS2↓, *NADH↓, *Imm↑, Apoptosis↑, TumCP↓, angioG↓, TumCMig↓, Ca+2↑, TumCCA↑, DNAdam↑, BAX↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, AIF↑, i-ROS↑, MMP↓, Cyt‑c↑, APAF1↑, Ca+2↑, MMP9↓, MMP2↓, PKCδ↓, ERK↓, H2O2↑, BAX↑, Bcl-2↓, DNAdam↑, lipid-P↑, ChemoSen↑, chemoP↑, *cardioP↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *BP↓, *AntiDiabetic↑, *Obesity↓, RenoP↑, *GastroP↑, hepatoP↑, *AChE↓, *cognitive↑, *BChE↓, *other↓, *BioAv↑,
5934- TV,    Protective Effects of Natural Antioxidants on Inflammatory Bowel Disease: Thymol and Its Pharmacological Properties
- Review, Var, NA
*Inflam↓, *antiOx↑, *Bacteria↓, AntiTum↑, *toxicity∅, *IBI↑, *ZO-1↑, *OCLN↑, *COX1↑, *TLR4↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *TAC↑, *NRF2↑, *GutMicro↑,
2411- UA,    Ursolic acid in health and disease
- Review, Var, NA
Inflam↓, antiOx↑, NF-kB↓, Bcl-xL↓, Bcl-2↓, cycD1/CCND1↓, Ki-67↓, CD31/PECAM-1↓, STAT3↓, EGFR↓, P53↑, P21↓, HK2↓, PKM2↓, ATP↓, lactateProd↓, p‑ERK↓, MMP↓, NO↑, ATM↑, Casp3↑, AMPK↑, JNK↑, FAO↑, FASN↓, *GSH↑, *SOD↑, *Catalase↑, *GPx↑, *GSTs↑, neuroP↑,
3790- UA,    Therapeutic applications of ursolic acid: a comprehensive review and utilization of predictive tools
*Inflam↓, *antiOx↑, AntiCan↑, *neuroP↑, *hepatoP↑, *cardioP↑, *MMP↑, *ROS↓, *PGC-1α↑, *BDNF↑, *cognitive↑, Bcl-2↓, Cyt‑c↑, DR5↑, Casp9↑, Casp8↑, Casp3↑, TumCCA↑, *BioAv↓, *Dose↝, *Half-Life↓, *Half-Life↓,
5018- UA,    Ursolic acid in cancer prevention and treatment: Molecular targets, pharmacokinetics and clinical studies
- Review, Var, NA
Inflam↓, TumCCA↑, chemoPv↑, TumMeta↓, antiOx↑, AntiViral↑, AntiDiabetic↑,
4869- Uro,    Urolithin A in Central Nervous System Disorders: Therapeutic Applications and Challenges
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*MitoP↑, *Inflam↓, *antiOx↑, *Risk↓, *Aβ↓, *p‑tau↓, *p62↓, *PARK2↑, *MMP↑, *ROS↓, *Strength↑, *CRP↓, *IL1β↓, *IL6↓, *TNF-α↓, *AMPK↑, *NF-kB↓, *MAPK↓, *p62↑, *NRF2↑, *SOD↑, *Catalase↑, *HO-1↑, *Ferroptosis↓, *lipid-P↓, *Cartilage↑, *PI3K↓, *Akt↓, *mTOR↓, *Apoptosis↓, *neuroP↑, *Bcl-2↓, *BAX↑, *Casp3↑, *ATP↑, *eff↑, *motorD↑, *NLRP3↓, *radioP↑, *BBB↑,
4865- Uro,    Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis
- in-vitro, Diabetic, NA - in-vitro, AD, NA
*antiOx↑, *neuroP↑, *Ca+2↓, *Aβ↓, *BACE/β-secretase↓, *p‑tau↓, *cognitive↑,
4872- Uro,    Urolithin A exhibits a neuroprotective effect against Alzheimer's disease by inhibiting DYRK1A activity
- in-vitro, AD, HEK293
*DYRK1A↓, *antiOx↑, *Inflam↓, *neuroP↑, *memory↑, *p‑tau↓, *Aβ↓, *neuroP↑,
4876- Uro,    Urolithin A in Health and Diseases: Prospects for Parkinson’s Disease Management
- Review, Park, NA - Review, AD, NA
*Inflam↓, *antiOx↓, *neuroP↑, *p‑tau↓, *Aβ↓, *eff↑, *BioAv↓, *BioAv↑, *GSH↑, *SOD↑, *lipid-P↓, *Catalase↑, *GSR↑, *GPx↑, *ROS↓, *NRF2↑, *GutMicro↑, *Risk↓, *BBB↓, *NLRP3↓, *MAOA↓,
4880- Uro,    Urolithins: A Prospective Alternative against Brain Aging
- Review, AD, NA
*cognitive↑, *memory↑, *antiOx↑, *BBB↑, *ROS↓, *lipid-P↓, *Catalase↑, *SOD↑, *GSR↑, *GPx↑, *CREB↑, *BDNF↑, *neuroP↑, *Inflam↓, *MitoP↑, *Aβ↓, *tau↓, *NLRP3↓, *SIRT1↑, *SIRT3↑,
4884- Uro,    A review of pomegranate supplementation: A promising remedial avenue for Alzheimer's disease
- Review, AD, NA
*antiOx↑, *neuroG↑, *Inflam↓, *cognitive↑,
4833- Uro,    Unveiling the potential of Urolithin A in Cancer Therapy: Mechanistic Insights to Future Perspectives of Nanomedicine
- Review, Var, NA - Review, AD, NA - Review, IBD, NA
BioAv↝, TumAuto↝, TumCG↓, TumMeta↓, ChemoSen↑, Imm↑, RadioS↑, BioAv↑, other↝, eff↓, *antiOx↓, *Inflam↓, AntiCan↓, AntiAge↑, chemoP↑, *neuroP↑, *ROS↓, *cognitive↑, *lipid-P↓, *cardioP↑, *TNF-α↓, *IL6↓, GutMicro↑, TumCCA↑, Apoptosis↑, angioG↓, NF-kB↓, PI3K↓, Akt↓, Casp↑, survivin↓, TumCP↓, cycD1/CCND1↓, cMyc↑, BAX↑, Bcl-2↓, COX2/PTGS2↓, P53↑, p38↑, *ROS↓, *SOD↑, *GPx↑, SIRT1↑, FOXO1↑, eff↑, ChemoSen↑,

Showing Research Papers: 801 to 850 of 870
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 870

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 8,   ARE/EpRE↑, 1,   Catalase↑, 2,   GCLM↑, 1,   GPx↑, 1,   GSH↓, 2,   GSH↑, 2,   GSR↑, 1,   GSTs↑, 1,   H2O2↓, 1,   H2O2↑, 2,   lipid-P↑, 1,   NQO1↑, 1,   NRF2↓, 1,   NRF2↑, 2,   ROS↓, 2,   ROS↑, 9,   ROS⇅, 2,   i-ROS↑, 1,   mt-ROS↑, 1,   SOD↑, 1,   SOD1↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 2,   ATP↓, 1,   MMP↓, 5,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 2,   AMPK↑, 2,   cMyc↓, 1,   cMyc↑, 1,   FAO↑, 1,   FASN↓, 1,   HK2↓, 1,   lactateProd↓, 1,   LDH↝, 1,   PKM2↓, 2,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 2,   Akt↑, 1,   p‑Akt↓, 1,   APAF1↑, 1,   Apoptosis↑, 11,   BAX↑, 4,   Bcl-2↓, 4,   Bcl-2↑, 1,   Bcl-xL↓, 2,   Casp↑, 3,   Casp3↑, 4,   Casp7↑, 1,   Casp8↑, 2,   Casp9↑, 3,   Cyt‑c↑, 4,   DR5↑, 1,   IAP1↓, 1,   IAP2/BIRC3↓, 1,   JNK↑, 2,   Necroptosis↑, 1,   p27/CDKN1B↑, 1,   p38↑, 2,   survivin↓, 3,   TumCD↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,   tumCV↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1↑, 2,   LC3B-II↑, 1,   p62↓, 1,   TumAuto↑, 1,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,   DNAdam↑, 5,   DNMT1↓, 1,   GADD45A↑, 1,   P53↑, 3,   PARP↓, 1,   cl‑PARP↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   cycA1/CCNA1↓, 2,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 4,   CycD3↑, 1,   cycE/CCNE↓, 2,   P21↓, 1,   P21↑, 3,   TumCCA↑, 14,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

cDC2↓, 1,   EMT↓, 3,   ERK↓, 2,   p‑ERK↓, 1,   FOXO1↑, 1,   GSK‐3β↓, 1,   p‑GSK‐3β↓, 1,   HDAC↓, 2,   mTOR↓, 1,   PI3K↓, 3,   p‑PI3K↓, 1,   PTEN↑, 1,   STAT3↓, 3,   TumCG↓, 4,  

Migration(tgid=13) ⓘ

Ca+2↑, 2,   CD31/PECAM-1↓, 1,   E-cadherin↓, 1,   Ki-67↓, 1,   MMP2↓, 2,   MMP9↓, 3,   MMPs↓, 1,   PKCδ↓, 1,   PRNP↑, 1,   TumCI↓, 2,   TumCMig↓, 2,   TumCP↓, 8,   TumMeta↓, 5,   Twist↓, 2,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 7,   angioG↑, 1,   EGFR↓, 1,   NO↑, 1,   VEGF↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   Imm↑, 2,   Inflam↓, 4,   NF-kB↓, 7,   p‑NF-kB↑, 1,   NK cell↑, 1,   PD-L1↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 1,   BioAv↝, 2,   ChemoSen↑, 7,   Dose↑, 1,   eff↓, 1,   eff↑, 7,   eff↝, 1,   RadioS↑, 1,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   AST↓, 1,   creat↓, 1,   EGFR↓, 1,   GutMicro↑, 1,   Ki-67↓, 1,   LDH↝, 1,   PD-L1↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 1,   AntiCan↑, 6,   AntiDiabetic↑, 1,   AntiTum↑, 3,   cardioP↑, 3,   chemoP↑, 4,   chemoPv↑, 2,   hepatoP↑, 3,   neuroP↑, 3,   radioP↑, 2,   RenoP↑, 1,   Risk↓, 1,   Risk↑, 1,   toxicity↓, 1,   TumVol↓, 1,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   Sepsis↓, 2,  
Total Targets: 165

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 6,   antiOx↑, 36,   Catalase↑, 11,   Ferroptosis↓, 2,   GCLC↑, 1,   GPx↑, 11,   GPx1↑, 1,   GPx4↑, 1,   GSH↑, 10,   GSR↑, 3,   GSTA1↑, 3,   GSTs↑, 4,   H2O2↓, 3,   HDL↑, 1,   HO-1↓, 1,   HO-1↑, 4,   Keap1↓, 1,   lipid-P↓, 11,   MDA↓, 2,   MPO↓, 2,   MPO↑, 1,   NADH↓, 1,   NQO1↑, 1,   NRF2↓, 1,   NRF2↑, 8,   PARK2↑, 1,   RNS↓, 1,   ROS↓, 21,   ROS↑, 1,   selenoP↑, 1,   SIRT3↑, 1,   SOD↑, 15,   SOD1↑, 1,   TAC↑, 3,   Thiols↑, 1,   TOS↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   mitResp↑, 1,   MMP↑, 5,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   AMPK↑, 1,   BUN↓, 1,   cMyc↓, 1,   CREB↑, 1,   LDH↓, 1,   LDL↓, 2,   NADPH↑, 1,   PPARγ↑, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   p‑Akt↓, 1,   Apoptosis↓, 2,   BAX↓, 3,   BAX↑, 1,   Bax:Bcl2↓, 1,   Bcl-2↓, 1,   Bcl-2↑, 1,   Casp3↓, 3,   Casp3↑, 1,   cl‑Casp3↓, 1,   proCasp3↓, 1,   Casp7↓, 1,   Ferroptosis↓, 2,   iNOS↓, 1,   iNOS↑, 1,   JNK↑, 1,   MAPK↓, 1,   MAPK↑, 1,   p‑p38↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   p‑cJun↓, 1,   other↓, 3,   other↑, 3,   other↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

DYRK1A↓, 1,   MitoP↑, 2,   p62↓, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Diff↑, 1,   mTOR↓, 1,   neuroG↑, 1,   PI3K↓, 1,   STAT3↑, 1,   VGCC↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   Ca+2↓, 3,   Cartilage↑, 1,   MMP13↓, 2,   MMP7↓, 1,   MMP9↓, 1,   PKCδ↓, 1,   TGF-β↓, 2,   TumCI↓, 1,   TumCP↓, 1,   ZO-1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 1,   NO↑, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 2,   GastroP↑, 1,   IBI↑, 1,   OCLN↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX1↑, 1,   COX2/PTGS2↓, 8,   CRP↓, 2,   CXCc↓, 1,   IFN-γ↓, 2,   IL10↑, 2,   IL12↓, 2,   IL1β↓, 8,   IL6↓, 5,   Imm↑, 2,   Inflam↓, 29,   IκB↑, 1,   MCP1/CCL2↓, 1,   MyD88↓, 2,   NF-kB↓, 9,   NF-kB↑, 1,   PGE2↓, 3,   TLR1↓, 1,   TLR2↓, 2,   TLR4↓, 3,   TNF-α↓, 8,   TRIF↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 5,   BChE↓, 1,   BDNF↑, 3,   ChAT↑, 1,   GABA↑, 2,   MAOA↓, 1,   tau↓, 1,   p‑tau↓, 6,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 10,   BACE/β-secretase↓, 2,   NLRP3↓, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 5,   BioAv↑, 8,   BioAv↝, 2,   Dose↝, 2,   eff↑, 7,   Half-Life↓, 3,   Half-Life↝, 3,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   BP↓, 1,   CRP↓, 2,   GutMicro↑, 2,   IL6↓, 5,   LDH↓, 1,   NOS2↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiCan↑, 2,   AntiDiabetic↑, 1,   cardioP↑, 8,   chemoP↑, 1,   cognitive↑, 11,   hepatoP↑, 8,   memory↑, 5,   motorD↑, 1,   neuroP↑, 23,   Obesity↓, 1,   Pain↓, 1,   radioP↑, 4,   RenoP↑, 5,   Risk↓, 2,   Strength↑, 1,   toxicity∅, 1,   Weight∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 3,   IRF3↓, 2,  
Total Targets: 176

Scientific Paper Hit Count for: antiOx, anti-oxidant activities
37 Lycopene
31 Curcumin
28 Thymoquinone
25 Resveratrol
25 Alpha-Lipoic-Acid
25 Hydrogen Gas
24 Selenium NanoParticles
24 Quercetin
20 Silymarin (Milk Thistle) silibinin
19 Rosmarinic acid
17 Ferulic acid
16 Astaxanthin
16 Chlorogenic acid
15 Silver-NanoParticles
15 EGCG (Epigallocatechin Gallate)
14 Eugenol
14 Honokiol
13 Berberine
13 Carvacrol
12 Baicalein
12 Propolis -bee glue
12 Fisetin
11 Allicin (mainly Garlic)
10 Coenzyme Q10
10 Vitamin C (Ascorbic Acid)
10 Luteolin
9 Crocetin
9 Dandelion Root
9 Magnetic Fields
9 Moringa oleifera
8 Melatonin
8 Selenium
8 chitosan
8 Sulforaphane (mainly Broccoli)
8 Emodin
8 Urolithin
7 Radiotherapy/Radiation
7 Apigenin (mainly Parsley)
7 α-Bisabolol / Chamomile oil
7 Cinnamon
7 Chemotherapy
7 Fucoidan
7 Ginger/6-Shogaol/Gingerol
7 Magnolol
6 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
6 Ashwagandha(Withaferin A)
6 Betulinic acid
6 Boron
6 Caffeic acid
6 Capsaicin
6 Chrysin
6 Cichoric acid / Chicoric acid
6 Hydroxycinnamic-acid
6 Ellagic acid
6 Ginkgo biloba
6 Isoliquiritigenin
6 Piperine
5 doxorubicin
5 Beta-Caryophyllene
5 Thymol-Thymus vulgaris
5 Carnosine
5 Centella asiatica / Gotu kola → asiaticoside
5 Vitamin E
5 Carvone
5 Ginkgo biloba-EGb 761
5 Hibiscus sabdariffa
5 HydroxyTyrosol
5 Pterostilbene
5 Selenite (Sodium)
4 Cisplatin
4 beta-carotene(VitA)
4 Bacopa monnieri
4 Caffeic Acid Phenethyl Ester (CAPE)
4 Date Fruit Extract
4 D-limonene
4 flavonoids
4 Shilajit/Fulvic Acid
4 Gallic acid
4 Garcinol
4 Hyperoside
4 iodine
4 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
4 Mung Bean Sprouts
4 Shikonin
3 Anthocyanins
3 Cynara scolymus/Globe Artichoke/Artichoke Extract
3 Ascorbyl Palmitate
3 Chyawanprash
3 Vitamin K2
3 Carica papaya leaf extract
3 Cucurbitacin
3 Dipyridamole
3 Geraniol
3 Inositol
3 isoquercitrin
3 Lecithin
3 Naringin
3 Nimbolide
3 Rutin
3 Salvia officinalis
3 Taurine
3 Ursolic acid
2 1,8-Cineole
2 5-fluorouracil
2 Anethole/trans-Anethole
2 Fennel Oil/Foeniculum vulgare
2 Aromatherapy
2 Vitamin B6,pyridoxine
2 Chocolate
2 Echinacea
2 Eurycomanone
2 Genistein (soy isoflavone)
2 Ginkgetin
2 High-Ozonide Oil
2 Huperzine A/Huperzia serrata
2 Isobavachalcone
2 isoflavones
2 isoorientin
2 Juglone
2 Methylene blue
2 Phenylbutyrate
2 Phenethyl isothiocyanate
2 Propyl gallate
2 Rauwolfia serpentina/Indian Snakeroot
2 α-Santalol/Sandalwood oil
2 Shankhpushpi
2 Vitamin B1/Thiamine
2 Vitamin B12
2 Folic Acid, Vit B9
2 Vitamin D3
1 Astragalus
1 Citric Acid
1 Ajoene (compound of Garlic)
1 alpha Linolenic acid
1 DTS(dibenzyl trisulphide) from Anamu
1 Artemisinin
1 Aloe anthraquinones
1 beta-glucans
1 Baicalin
1 Biochanin A
1 Cannabidiol
1 Boswellia (frankincense)
1 Bruteridin(bergamot juice)
1 Carnosic acid
1 Celastrol
1 Chlorophyllin
1 Choline
1 methotrexate
1 Copper and Cu NanoParticles
1 Deguelin
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 diet Methionine-Restricted Diet
1 Aspirin
1 eicosapentaenoic acid
1 Fenbendazole
1 Gamma-aminobutyric acid
1 Gambogic Acid
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Ginkgolide B
1 Germacranolide sesquiterpene lactone
1 hydrogen sulfide
1 Helleborus niger extracts – Christmas Rose
1 Oleuropein
1 Indole-3-carbinol
1 Butein
1 Scopoletin
1 Kaempferol
1 Lutein
1 Methyl salicylate / Sweet Birch oil
1 Magnetic Field Rotating
1 Methylsulfonylmethane
1 N-Acetyl-Cysteine
1 nicotinamide adenine dinucleotide
1 Neem
1 Oleocanthal
1 Oregano
1 Phenolic Acids
1 Polyphenols
1 Phosphatidylserine
1 Psoralidin
1 Perilla
1 Gold NanoParticles
1 Sinapic acid
1 Sulfasalazine
1 Sesame seeds and Oil
1 Iron
1 Spermidine
1 Terpinen-4-ol / Tea Tree Oil
1 cetuximab
1 Ginseng
1 Aflavin-3,3′-digallate
1 Vanillic Acid
1 Dichloroacetate
1 probiotics
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1103  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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