Radiotherapy/Radiation Cancer Research Results

Rad, Radiotherapy/Radiation: Click to Expand ⟱
Features:
Treatment of disease with radiation, especially by selective irradiation with x-rays or other ionizing radiation and by ingestion of radioisotopes.

Radiosensitizer
Atorvaqone, (mitochondria inhibitor) decrease O2 consumption making more O2 available as a radiosensitizer.
-Hypoxia (low oxygen levels) within tumors is a major cause of resistance to radiotherapy


Scientific Papers found: Click to Expand⟱
8405- LT,  Rad,    Luteolin's role as a radiosensitizer by promoting cell death and ROS modulation
- Review, NSCLC, NA
RadioS↑, ROS↑,
2917- LT,  Rad,    Luteolin acts as a radiosensitizer in non‑small cell lung cancer cells by enhancing apoptotic cell death through activation of a p38/ROS/caspase cascade
- in-vitro, Lung, NA
Bcl-2↓, Casp3↑, Casp8↑, Casp9↑, p‑p38↑, ROS↑, RadioS↑,
8422- Lyco,  Rad,    Dietary and Serum Lycopene Levels in Prostate Cancer Patients Undergoing Intensity-Modulated Radiation Therapy
- Trial, Pca, NA
Weight↑, other?, Dose↝, Dose↝, *Half-Life↝, radioP?,
8423- Lyco,  Rad,    Tomato Juice Consumption Could Improve Breast Skin Adverse Effects of Radiotherapy in Breast Cancer Patients
- Trial, BC, NA
Dose↝, radioP↑, 8-oxo-dG↓,
8509- MAG,  Rad,    The In Vivo Radiosensitizing Effect of Magnolol on Tumor Growth of Hepatocellular Carcinoma
- in-vivo, HCC, NA
TumVol↓, TumW↓, *ERK↓, *NF-kB↓, Casp3↑, Casp9↑, RadioS↑, *toxicity↓, Ki-67↓, IL1β↓, TNF-α↓,
8933- MBS,  Rad,    The evaluation of radio-sensitivity of mung bean proteins aqueous extract on MCF-7, hela and fibroblast cell line
- in-vitro, BC, MCF7 - in-vitro, Cerv, HeLa
TumCP↓, selectivity?, RadioS↑, radioP↑,
8630- MBZ,  Rad,    Microtubule-targeting agents can sensitize cancer cells to ionizing radiation by an interphase-based mechanism
- in-vitro, GBM, GL261 - in-vitro, GBM, GBM14
RadioS↑, γH2AX↑, eff↑, mitA↑,
8634- MBZ,  Rad,    Mebendazole Potentiates Radiation Therapy in Triple-Negative Breast Cancer
- vitro+vivo, BC, MCF7 - in-vitro, BC, T47D - in-vitro, BC, MDA-MB-231
RadioS↑, TumCCA↑, DNAdam↑, Apoptosis↑, TumCD↑, *toxicity↓,
8651- MBZ,  Rad,    Mebendazole and radiation in combination increase survival through anticancer mechanisms in an intracranial rodent model of malignant meningioma
- in-vitro, Var, NA
Dose↝, RadioS↑, cl‑Casp3↑, Apoptosis↑, TumCP↓, angioG↓,
8821- MCP,  Rad,    Modified Citrus Pectin as a Potential Sensitizer for Radiotherapy in Prostate Cancer
- in-vitro, Pca, PC3 - in-vitro, Pca, DU145
Gal-3↓, TumCP↓, angioG↓, Apoptosis↑, RadioS?, BAX↓, DNArepair↓, PCNA↓, TumCI↓, TumCCA↑, ROS↑,
8719- MeJa,  Cisplatin,  Rad,    Enhanced killing of cervical cancer cells by combinations of methyl jasmonate with cisplatin, X or alpha radiation
- in-vitro, Cerv, SiHa - in-vitro, Cerv, CaSki - in-vitro, Cerv, HeLa - in-vitro, Cerv, C33A
RadioS↑, ChemoSen↑,
8724- MeJa,  Rad,    Methyl jasmonate enhances the radiation sensitivity of esophageal carcinoma cells by inhibiting the 11-ketoprostaglandin reductase activity of AKR1C3
- in-vitro, ESCC, KYSE170
AKR1C3/17β-HSD5/PGF Synthase↓, ROS↑, RadioS↑,
8752- MeSA,  Rad,    Methylseleninic Acid Induces Lipid Peroxidation and Radiation Sensitivity in Head and Neck Cancer Cells
- in-vitro, HNSCC, CAL27 - in-vitro, SCC, SCC25
selectivity↑, RadioS↑, GSH↓, lipid-P↑, OCR↑,
3487- MF,  Rad,    High-specificity protection against radiation-induced bone loss by a pulsed electromagnetic field
- Review, Var, NA
radioP↑, *Ca+2↑, RAS↑, MAPK↓,
517- MF,  Rad,    Therapeutic Electromagnetic Field (TEMF) and gamma irradiation on human breast cancer xenograft growth, angiogenesis and metastasis
- in-vivo, BC, MDA-MB-231
TumMeta↓, TumCG↓,
2251- MF,  Rad,    BEMER Electromagnetic Field Therapy Reduces Cancer Cell Radioresistance by Enhanced ROS Formation and Induced DNA Damage
- in-vitro, Lung, A549 - in-vitro, HNSCC, UTSCC15 - in-vitro, CRC, DLD1 - in-vitro, PC, MIA PaCa-2
RadioS↑, DNAdam↑, ROS↑, ChemoSen∅, Pyruv↓, ADP:ATP↓, ROS↑,
5245- MFrot,  Rad,    The hemoprotective effects of a rotary magnetic field in mice exposed to γ irradiation
- in-vivo, Nor, NA
*OS↑, *radioP↑,
1775- MLT,  Chemo,  Rad,    A Systematic Review of the Chemo/Radioprotective Effects of Melatonin against Ototoxic Adverse Effects Induced by Chemotherapy and Radiotherapy
- Review, Var, NA
chemoP↑, radioP↑, antiOx↑, Inflam↑,
8664- MLT,  Rad,    Melatonin Supplementation for Cancer-Related Fatigue in Patients With Early Stage Breast Cancer Receiving Radiotherapy: A Double-Blind Placebo-Controlled Trial
- Trial, BC, NA
fatigue∅,
8665- MLT,  Rad,    Efficacy of Melatonin in Alleviating Radiotherapy-Induced Fatigue, Anxiety, and Depression in Breast Cancer Patients: A Randomized, Triple-Blind, Placebo-Controlled Trial
- Trial, BC, NA
Dose↝, fatigue↓, ANXi↓, antiD↑,
8667- MLT,  Rad,    The protective effects of melatonin on blood cell counts of rectal cancer patients following radio-chemotherapy: a randomized controlled trial
- Trial, CRC, NA
Dose↝, RBC↑,
2939- NAD,  Rad,    NMN ameliorated radiation induced damage in NRF2-deficient cell and mice via regulating SIRT6 and SIRT7
- in-vitro, Nor, NA
*SIRT6↑, *DNAdam↓, *radioP↑, *ROS↓,
1311- NarG,  Rad,    Naringenin sensitizes lung cancer NCI-H23 cells to radiation by downregulation of akt expression and metastasis while promoting apoptosis
- in-vitro, Lung, H23
tumCV↓, ROS↑, Casp3↑, p‑Akt↓, Akt↓, MMP2↓, P21↓,
1270- NCL,  Rad,    Niclosamide enhances the antitumor effects of radiation by inhibiting the hypoxia-inducible factor-1α/vascular endothelial growth factor signaling pathway in human lung cancer cells
- in-vivo, Lung, NA
Hif1a↓, VEGF↓,
2063- PB,  Rad,    Phenylbutyrate sensitizes human glioblastoma cells lacking wild-type p53 function to ionizing radiation
- in-vitro, GBM, U87MG - NA, NA, U251
RadioS↑, eff↝, P53↝,
2064- PB,  Rad,    Phenylbutyrate Attenuates the Expression of Bcl-XL, DNA-PK, Caveolin-1, and VEGF in Prostate Cancer Cells
- in-vitro, Pca, PC3 - in-vitro, Pca, DU145 - in-vitro, Pca, LNCaP
Bcl-xL↓, Cav1↓, VEGF↓, RadioS↑, chemoP↑, HDAC↓, *toxicity↓, Diff↑, Prot↓,
2066- PB,  Rad,    Butyric acid prodrugs are histone deacetylase inhibitors that show antineoplastic activity and radiosensitizing capacity in the treatment of malignant gliomas
- in-vitro, GBM, U251
RadioS↑,
1683- PBG,  Rad,    Protective effect of propolis in protecting against radiation-induced oxidative stress in the liver as a distant organ
- in-vivo, Nor, NA
GPx↑, SOD↓, RadioS↑,
1987- PTL,  Rad,    A NADPH oxidase dependent redox signaling pathway mediates the selective radiosensitization effect of parthenolide in prostate cancer cells
- in-vitro, Pca, PC3 - in-vitro, Nor, PrEC
selectivity↑, RadioS↑, ROS↑, *ROS∅, NADPH↑, Trx↓, PI3K↑, Akt↑, p‑FOXO3↓, SOD2↓, Catalase↓, radioP↑, *NADPH∅, *GSH↑, *GSH/GSSG↑, *NRF2↑,
1493- QC,  Rad,    New quercetin-coated titanate nanotubes and their radiosensitization effect on human bladder cancer
- in-vivo, Bladder, NA
RadioS↑, ChemoSen↑,
5971- Rad,  CET,    Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
- Trial, HNSCC, NA
OS↑,
7576- Rad,  HPT,    Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: results from five randomized controlled trials. International Collaborative Hyperthermia Group
- Trial, Nor, NA
RadioS↑,
5969- Rad,  CET,    Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
- Trial, HNSCC, NA
Dose↝, radioP↑, OS↑,
5857- RES,  CAP,  Rad,    Resveratrol and capsaicin as safer radiosensitizers for colorectal cancer compared to 5-fluorouracil
- in-vivo, Var, NA
RadioS↑, hepatoP↝, toxicity↓,
3075- RES,  Rad,    The Protection Effect of Resveratrol Against Radiation-Induced Inflammatory Bowel Disease via NLRP-3 Inflammasome Repression in Mice
- in-vivo, Nor, NA
*SIRT1↑, *radioP↑, *NLRP3↓, *Weight↑, *IL1β↓,
3012- RosA,  Rad,    Rosmarinic Acid Prevents Radiation-Induced Pulmonary Fibrosis Through Attenuation of ROSMYPT1TGFβ1 Signaling Via miR-19b-3p
- in-vitro, Nor, IMR90
*Inflam↓, *ROS↓, *p‑NF-kB↓, *Rho↓, *ROCK1↓, *radioP↑, *MCP1/CCL2↓, *RANTES↓, *ICAM-1↓, *PGC1A↑, *NOX4↓, *Dose↝,
3015- RosA,  Rad,    Rosmarinic Acid Prevents Radiation-Induced Pulmonary Fibrosis Through Attenuation of ROS/MYPT1/TGFβ1 Signaling Via miR-19b-3p
- in-vivo, Nor, IMR90
*radioP↑, *Inflam↓, *ROS↓, *NF-kB↓, *Rho↓, *ROCK1↓, *other↓,
4994- Sal,  Rad,    Salinomycin overcomes radioresistance in nasopharyngeal carcinoma cells by inhibiting Nrf2 level and promoting ROS generation
- in-vitro, NPC, NA
AntiCan↑, RadioS↓, Apoptosis↑, NRF2↓, ROS↑, DNAdam↑,
5138- SAS,  Rad,    Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc-, leading to glutathione depletion
- vitro+vivo, GBM, NA
cystine↓, GSH↓, ROS↑, RadioS↑, eff↓, DNAdam↑, OS↑,
5038- SAS,  Rad,    Sulfasalazine, an inhibitor of the cystine-glutamate antiporter, reduces DNA damage repair and enhances radiosensitivity in murine B16F10 melanoma
- in-vivo, Melanoma, B16-F10
xCT/SLC7A11↓, ROS↑, RadioS↓, GSH↓, selectivity↑, DNArepair↓, TumCCA↑, H2O2↑, Dose↝,
6220- Se,  CUR,  Rad,    Selenium-Curcumin-PEG Nanoparticles Radiosensitization for Intensity-Modulated Radiation Therapy of Lung Tumor Cells: In Vitro Synergistic Combination Therapy
- in-vitro, Lung, A549
RadioS↑, TumCD↑, ROS↑, Imm↑, angioG↓, BioAv↑, TumCP↓, Apoptosis↓, TumMeta↓, CompStab↑,
4737- Se,  Rad,    Nrf2-modulation by seleno-hormetic agents and its potential for radiation protection
- in-vivo, Var, NA
radioP↑, *NRF2↑, NRF2↓,
4615- Se,  Rad,    Selenium as an adjuvant for modification of radiation response
- Review, Nor, NA
*antiOx↑, *radioP↑, *GSH↑, *GPx↑, *Dose↝, selectivity↑, RadioS↑,
4613- Se,  Rad,    Effect of Selenium and Selenoproteins on Radiation Resistance
- Review, Nor, NA
*selenoP↑, *GPx1↑, *GPx4↑, *lipid-P↓, *DNAdam↓, *ROS↓, *radioP↑,
4612- SeNPs,  Rad,    Histopathological Evaluation of Radioprotective Effects: Selenium Nanoparticles Protect Lung Tissue from Radiation Damage
- in-vivo, Nor, NA
*radioP↑, *Inflam↓, *antiOx↑, *Dose↝, *DNAdam↓, *ROS↓, *SOD↑, *GPx↑, *Dose↝, *Synergy↑,
4611- SeNPs,  Rad,    Radioprotective Effect of Selenium Nanoparticles: A Mini Review
- Review, Var, NA
*antiOx↑, *Inflam↓, *radioP↑, *ROCK1↓, *DNAdam↓, *Apoptosis↓, *RadioS↑, *Dose↝,
1470- SFN,  Rad,    Sulforaphane induces ROS mediated induction of NKG2D ligands in human cancer cell lines and enhances susceptibility to NK cell mediated lysis
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vitro, Lung, A549 - in-vitro, lymphoma, U937
eff↓, ROS↑, NKG2D↑,
3306- SIL,  Rad,    Radioprotective and radiosensitizing properties of silymarin/silibinin in response to ionizing radiation
- Review, Var, NA
radioP↑, RadioS↑, TumCMig↓, TumCI↓, angioG↓, Apoptosis↑, DNAdam↓, ROS↑, *ROS↓, *Inflam↓,
3297- SIL,  Rad,    Studies on radiation sensitization efficacy by silymarin in colon carcinoma cells
- in-vitro, CRC, HCT15 - in-vitro, CRC, RKO
TumCP↓, RadioS↑, TumCCA↑, DNAdam↓, MMP↓, ROS↓, *radioP↑,
4610- SSE,  Rad,    Protection during radiotherapy: selenium
- Review, Var, NA
*radioP↑, *antiOx↑, *Inflam↓, *DNAdam↓, *lipid-P↓, *selenoP↑, *GPx1↑, *BUN↓,

Showing Research Papers: 101 to 150 of 160
Prev Page 3 of 4 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 160

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   Catalase↓, 1,   cystine↓, 1,   GPx↑, 1,   GPx4↓, 1,   GSH↓, 8,   GSH/GSSG↓, 1,   H2O2↑, 2,   HO-1↓, 1,   lipid-P↑, 2,   NRF2↓, 2,   NRF2↑, 2,   ROS↓, 2,   ROS↑, 41,   SOD↓, 1,   SOD2↓, 1,   TBARS↑, 1,   Thiols↓, 1,   Trx↓, 1,   TrxR↓, 3,   xCT/SLC7A11↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↓, 1,   mtDam↑, 1,   OCR↑, 1,   p‑PDH↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   ALDOA↓, 1,   AMPK↑, 1,   ATP↓, 2,   ECAR↓, 3,   GAPDH↓, 1,   glucose↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 2,   HK1↓, 1,   HK2↓, 1,   lactateProd↓, 2,   NADPH↑, 1,   PDK1 / PDPK1↓, 1,   PDKs↑, 1,   PKM2↓, 1,   PPP↑, 1,   Pyruv↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   Apoptosis↑, 23,   BAX↓, 1,   BAX↑, 4,   Bax:Bcl2↑, 1,   Bcl-2↓, 6,   Bcl-xL↓, 1,   Casp3↑, 8,   cl‑Casp3↑, 1,   Casp8↑, 1,   Casp9↑, 4,   Cyt‑c↑, 2,   Ferroptosis↑, 1,   ICD↑, 1,   p38↑, 2,   p‑p38↑, 1,   survivin↓, 1,   TumCD↑, 4,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 2,   Akt↑, 1,   p‑Akt↓, 3,   EGFR↓, 1,   ERK↓, 2,   ERK↑, 1,   p‑ERK↓, 1,   JNK↓, 1,   JNK↑, 1,   MAPK↓, 1,   mTOR↓, 1,   PI3K↓, 2,   PI3K↑, 1,   RAS↑, 1,   STAT3↓, 1,   p‑STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

p‑FOXO3↓, 1,   HATs↓, 1,   HDAC↓, 1,   OCT4↓, 1,   other?, 1,   other↓, 1,   other↑, 1,   other↝, 3,   Prot↓, 1,   SOX2↓, 1,   tumCV↓, 6,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 1,   HSP70/HSPA5↑, 1,   HSP90↓, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   TumAuto↑, 4,  

DNA Damage & Repair(tgid=10) ⓘ

8-oxo-dG↓, 1,   BRCA2↓, 4,   DNAdam↓, 2,   DNAdam↑, 10,   DNArepair↓, 5,   P53↑, 4,   P53↝, 1,   PARP↓, 1,   cl‑PARP↑, 2,   PCNA↓, 1,   γH2AX↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↓, 1,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 1,   Ki-67↓, 1,   mitA↑, 1,   P21↓, 1,   TumCCA↓, 1,   TumCCA↑, 17,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   ALDH1A1↓, 1,   CSCs↓, 3,   Diff↑, 1,   EIF4E↓, 1,   Ki-67↓, 1,   mTORC1↓, 1,   TumCG↓, 8,   TumCP?, 1,   TumCP↓, 15,  

Migration(tgid=13) ⓘ

Cav1↓, 1,   EMT↓, 2,   MMP2↓, 2,   MMP9↓, 2,   TGF-β↓, 2,   TumCI↓, 4,   TumCMig↓, 5,   TumMeta↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 7,   Hif1a↓, 5,   Hypoxia↓, 3,   VCAM-1↓, 1,   VEGF↓, 4,  

Barriers & Transport(tgid=15) ⓘ

EPR↑, 2,   MMP↓, 7,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD44↓, 1,   COX2/PTGS2↓, 4,   Gal-3↓, 1,   HMGB1↑, 1,   IL1β↓, 2,   IL6↓, 2,   Imm↑, 4,   Inflam↓, 4,   Inflam↑, 1,   MCP1/CCL2↓, 1,   NF-kB↓, 5,   NF-kB↑, 1,   p‑NF-kB↓, 1,   PSA↓, 1,   RANTES↓, 1,   TNF-α↓, 2,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 1,   e-pH↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AKR1C3/17β-HSD5/PGF Synthase↓, 1,   AR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 2,   ChemoSen↑, 12,   ChemoSen∅, 1,   CompStab↑, 1,   Dose?, 1,   Dose↓, 1,   Dose↑, 3,   Dose⇅, 1,   Dose↝, 24,   Dose∅, 1,   eff↓, 3,   eff↑, 13,   eff⇅, 1,   eff↝, 3,   eff∅, 1,   Half-Life↝, 1,   RadioS?, 2,   RadioS↓, 3,   RadioS↑, 85,   RadioS↝, 1,   RadioS∅, 1,   selectivity?, 1,   selectivity↓, 1,   selectivity↑, 19,   Synergy↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   BloodF↑, 4,   CRP↓, 1,   EGFR↓, 1,   IL6↓, 2,   LDH↝, 1,   NLR↓, 1,   PSA↓, 1,   RBC↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   antiD↑, 1,   AntiTum↑, 3,   AntiTum∅, 1,   ANXi↓, 1,   chemoP↑, 5,   CR↑, 2,   fatigue↓, 1,   fatigue∅, 1,   hepatoP↑, 1,   hepatoP↝, 1,   LC↑, 2,   Mucositis↓, 2,   NKG2D↑, 1,   OS↑, 12,   Pain↓, 4,   QoL↑, 2,   radioP?, 1,   radioP↑, 21,   RenoP↑, 1,   Risk↓, 4,   toxicity↓, 2,   toxicity↝, 2,   TR↑, 1,   TumVol↓, 3,   TumW↓, 1,   Weight↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 1,  
Total Targets: 221

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 5,   Catalase↑, 3,   GPx↑, 3,   GPx1↑, 2,   GPx4↑, 1,   GSH↓, 1,   GSH↑, 6,   GSH/GSSG↑, 1,   HO-1↑, 2,   Iron↓, 1,   lipid-P↓, 2,   MDA↓, 2,   MDA↑, 1,   NOX4↓, 1,   NRF2↓, 1,   NRF2↑, 5,   Prx↑, 1,   ROS↓, 22,   ROS∅, 1,   selenoP↑, 4,   SOD↑, 5,   SOD1↑, 1,   TAC↑, 1,   Trx↑, 1,   TrxR1↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,   compIII↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ATP↑, 1,   glucose↝, 1,   NADPH↑, 1,   NADPH∅, 1,   PGC1A↑, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   Apoptosis↑, 1,   BAX↓, 1,   Bcl-2↑, 1,   Casp3↓, 3,   cl‑Casp3↓, 1,   p‑p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   p‑Akt↑, 1,   ERK↓, 1,   ERK↑, 1,   JNK↓, 1,   Mst1↓, 1,   STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

p‑cJun↓, 1,   DNMTs↓, 1,   HDAC↑, 1,   other↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 7,   P53↓, 1,   SIRT6↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p300↓, 1,  

Migration(tgid=13) ⓘ

AP-1↓, 1,   Ca+2↓, 1,   Ca+2↑, 1,   Rho↓, 2,   ROCK1↓, 3,   TGF-β↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

VEGF↓, 1,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   DR4↓, 1,   ICAM-1↓, 2,   IL10↑, 1,   IL1β↓, 2,   Inflam↓, 7,   MCP1/CCL2↓, 1,   NF-kB↓, 3,   p‑NF-kB↓, 1,   NLRP3↓, 1,   RANTES↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 8,   eff↑, 1,   eff↝, 1,   Half-Life↝, 1,   RadioS↑, 1,   Synergy↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

BUN↓, 1,   LDH↓, 1,  

Functional Outcomes(tgid=23) ⓘ

cognitive↑, 2,   hepatoP↑, 1,   Learn↑, 1,   memory↑, 1,   OS↑, 1,   QoL↑, 1,   radioP↑, 24,   toxicity?, 1,   toxicity↓, 6,   toxicity↝, 1,   toxicity∅, 1,   Weight↑, 1,   Wound Healing↓, 1,   Wound Healing↑, 1,  
Total Targets: 100

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:201  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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