Inflam Cancer Research Results

Inflam, inflammation: Click to Expand ⟱
Source:
Type:
Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.
Scientific Papers found: Click to Expand⟱
1792- CUR,  LEC,    Chondroprotective effect of curcumin and lecithin complex in human chondrocytes stimulated by IL-1β via an anti-inflammatory mechanism
- in-vitro, Arthritis, RAW264.7 - NA, NA, HCC-38
*Inflam↓, *NF-kB↓, *iNOS↓, *COX2↓, *NO↓, *PGE2↓, *MMPs↑, *TIMP1↑, *BioEnh↑,
1418- CUR,    Potential complementary and/or synergistic effects of curcumin and boswellic acids for management of osteoarthritis
- Review, Arthritis, NA
*COX2↓, *Inflam↓, *5LO↓, *NO↓, *NF-kB↓, *TNF-α↓, *IL1↓, *IL2↑, *IL6↓, *IL8↓, *IL12↓, *MCP1↓, *PGE2↓, *MMP2↓, *MMP3↓, *MMP9↓, *NLRP3↓, *ROS↓,
133- CUR,    Curcumin inhibits prostate cancer by targeting PGK1 in the FOXD3/miR-143 axis
- in-vitro, Pca, DU145 - in-vitro, Pca, PC3
miR-143↑, PDK1↓, FOXD3↑, TumCP↓, TumCMig↓, *Inflam↓, *antiOx↑, *chemoPv↑, RadioS↑, ChemoSen↑,
158- CUR,    Curcumin-targeting pericellular serine protease matriptase role in suppression of prostate cancer cell invasion, tumor growth, and metastasis
- vitro+vivo, Pca, LNCaP - in-vitro, Pca, PC3
MMP9↓, Matr↓, Inflam↓, antiOx↓, NF-kB↓, COX2↓, iNOS↓, TumCMig↓, TumCI↓,
5071- dietSTF,    Unraveling the impact of intermittent fasting in cancer prevention, mitigation, and treatment: A narrative review
- Review, Var, NA - Review, AD, NA
Risk↓, TumCMig↓, IGF-1↓, TumAuto↑, Inflam↓, ChemoSen↑, Apoptosis↑, chemoP↑, *glucose↓, *AntiDiabetic↑, *cardioP↑, *LDL↓, *BP↓, *neuroP↑, *cognitive↑, *memory↑, *OS↑, *QoL↑, Imm↑, TumCG↓, ChemoSideEff↓, QoL↑,
3708- dietSTF,    Fasting as a Therapy in Neurological Disease
*PGC-1α↑, *AMPK↑, *adiP↑, *glucose↓, *Insulin↓, *mTOR↓, *IL6↓, *TNF-α↓, *cognitive↑, *Inflam↓, *eff↑, *neuroP↑, ChemoSen↑, eff↓, chemoP↑, *eff↑,
6289- DL,    D-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis
- in-vivo, Var, NA
COX2↓, *GSH↑, *GPx↑, *Catalase↑, Bcl-2↓, BAX↑, *chemoPv↑, *Inflam↓, *ROS↓, *RAS↓,
6275- DL,    Oral administration of d-limonene controls inflammation in rat colitis and displays anti-inflammatory properties as diet supplementation in humans
- in-vivo, Col, NA
*TNF-α↓, *Inflam↓, *IL6↓,
6288- DL,    From Citrus to Clinic: Limonene’s Journey Through Preclinical Research, Clinical Trials, and Formulation Innovations
- Review, Var, NA - Review, AD, NA
other↑, DDS↑, *antiOx↑, *Inflam↓, *AntiDiabetic↑, *neuroP↑, *Imm↑, *Wound Healing↑, *other↑, *BioAv↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *DNAdam↓, *AntiDiabetic↑, Casp3↑, Casp9↑, BAX↑, Bcl-2↓, *AChE↓, *BChE↓, *Aβ↓, *ROS↓, *toxicity?,
6286- DL,    d-Limonene inhibits cytokines and chemokines expression by regulating NF-kappaB and STAT in HaCat cells and DNCB-induced atopic dermatitis in BALB/c mice
- in-vitro, Nor, NA
*Inflam↓,
6282- DL,    Limonene Exerts Anti-Inflammatory Effect on LPS-Induced Jejunal Injury in Mice by Inhibiting NF-κB/AP-1 Pathway
- in-vivo, IBD, NA
*RenoP↑, *creat↓, *Inflam↓, *TNF-α↓, *IL1β↓, *COX2↓, *ROS↓, *NRF2↑, *GastroP↑, *TLR4↓, *NF-kB↓, *AP-1↓, *Sepsis↓,
6280- DL,    Biochemical significance of limonene and its metabolites: future prospects for designing and developing highly potent anticancer drugs
- Review, Var, NA
BAX↑, Cyt‑c↑, Casp3↑, Casp9↑, TGF-β↑, Bcl-2↓, VEGF↓, AntiTum↑, *Inflam↓, *Bacteria↓,
6283- DL,    D-limonene inhibits peritoneal adhesion formation in rats via anti-inflammatory, anti-angiogenic, and antioxidative effects
- in-vivo, Nor, NA
*TGF-β1↓, *VEGF↓, *MDA↓, *GPx↑, *Catalase↑, *Inflam↓, *ROS↓, *angioG↓,
6343- DRE,    Dandelion root extract affects ESCC progression via regulating multiple signal pathways
- vitro+vivo, ESCC, NA
*Inflam↓, TumCG↓, TumCP↓, TumCMig↓, TumCI↓, Apoptosis↓, TumCG↓, PI3K↓, p‑Akt↓, RAS↓, Raf↓, p‑ERK↓, Bcl-2↓, BAX↑,
6344- DRE,    Dandelion: Purported Benefits, Side Effects & More
- Review, Var, NA
*other↝, *hepatoP↑, *ALAT↓, *MDA↓, *TNF-α↓, *IL6↓, *antiOx↑, *Inflam↓, *proCasp3↓, Casp3↑, tumCV↓, TNF-α↑, IL1↑,
6348- DRE,    New prospects in oncotherapy: bioactive compounds from Taraxacum officinale
- Review, Var, NA
Dose↝, TumCP↓, toxicity↓, *AntiDiabetic↑, *antiOx↑, *hepatoP↑, *diuretic↑, *Inflam↓, *neuroP↑, *Imm↑, eff↑, Apoptosis↑, tumCV↓, selectivity↑, TumCMig↓, EMT↓, MMP2↓, MMP9↓, Wnt↓, β-catenin/ZEB1↓, PI3K↓, Akt↓, JNK↓, ERK↓,
6350- DRE,    Tracking Evidences of Dandelion for the Treatment of Cancer: From Chemical Composition, Bioactivity, Signaling Pathways in Cancer Cells to Perspective Study
- Review, Var, NA
AntiCan↑, *Bacteria↓, *Inflam↓, *antiOx↑, TumCCA↑, Apoptosis↑, MOMP↑, Cyt‑c↑, APAF1↑, Casp9↑, Casp3↑, MMP↓, Bcl-2↓, TumCMig↓, TumCI↓, Wnt↓, β-catenin/ZEB1↓, MMP2↓, MMP9↓, TumAuto↑, mTOR↓, 4E-BP1↓, Glycolysis↓, angioG↓,
6319- DRE,    Efficient induction of extrinsic cell death by dandelion root extract in human chronic myelomonocytic leukemia (CMML) cells
- in-vitro, AML, MV411 - in-vitro, AML, HL-60
Apoptosis↑, TumAuto↑, *toxicity↓, selectivity↑, Casp8↑, MMP↓, *Inflam↓, *antiOx↑, *AntiCan↑, DNAdam↑, cl‑Casp3↑, tumCV↓, ROS↑,
6357- DRE,    New Perspectives on the Effect of Dandelion, Its Food Products and Other Preparations on the Cardiovascular System and Its Diseases
- Review, Nor, NA
*cardioP↑, *Dose↝, *Dose↝, *toxicity∅, *toxicity↓, *BP↓, *Inflam↓, *Bacteria↓, *Imm↑, *lipid-P↓, *AST↓, *ALAT↓, *AntiAg↑, *ROS↓, *AntiThr↑,
6353- DRE,  Cisplatin,    Insights Into Protective Mechanisms of Dandelion Leaf Extract Against Cisplatin-Induced Nephrotoxicity in Rats: Role of Inhibitory Effect on Inflammatory and Apoptotic Pathways
- in-vivo, Nor, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Cyt‑c↓, *DNAdam↓, *GSH↑, *SOD↑, *Albumin↝, *creat↓, *BUN↓, *RenoP↑, *lipid-P↓, *TNF-α↓, *Casp3↓, *Casp9↓, *chemoP↑,
6365- DRE,    AN OVERVIEW OF THERAPEUTIC POTENTIALS OF TARAXACUM OFFICINALE (DANDELION): A TRADITIONALLY VALUABLE HERB WITH A REACH HISTORICAL BACKGROUND
- Review, Var, NA
*Inflam↓, *AntiTum↑, *Imm↑, *antiOx↑, *AntiDiabetic↑, *diuretic↑, *RenoP↑, *hepatoP↑, *neuroP↑, AntiTum↑, TNF-α↑, IL1β↑, Apoptosis↑, MMP2↓, MMP9↑, eff↑, Diff↑, *ROS↓, *HO-1↑, *NRF2↑, *lipid-P↓,
6359- DRE,    Natural Health Products (NHP’s) and Natural Compounds as Therapeutic Agents for the Treatment of Cancer; Mechanisms of Anti-Cancer Activity of Natural Compounds and Overall Trends
- Review, Var, NA
*antiOx↑, *Inflam↓, Dose↝, PI3K↓, Akt↓, NF-kB↓,
6363- DRE,    Therapeutic Potential of Dandelion (Taraxacum officinale) Root Extract in Colon Cancer: A Comprehensive Review
- in-vitro, CRC, NA
Apoptosis↑, *Inflam↓, TLR4↓, NF-kB↓, *GutMicro↑, mtDam↑, *ROS↓, Casp1↑, TNF-α↑, Bcl-2↓, PARP↓, MMP↓, Cyt‑c↓, Casp3↑, TumVol↓, COX2↓, iNOS↓, ROS↑, selectivity↑, TumCMig↓, TumCI↓, ER Stress↑, PERK↑, eIF2α↑, ATF4↑, CHOP↑, TumCCA↑, cycD1/CCND1↓, P21↓, P53↑, BioAv↝, Half-Life↝,
4914- DSF,  immuno,    Disulfiram and cancer immunotherapy: Advanced nano-delivery systems and potential therapeutic strategies
- Review, Var, NA
AntiTum↑, eff↑, ALDH↓, Dose↝, RadioS↑, angioG↓, TumMeta↓, BioAv↝, ROS↑, DNAdam↑, P-gp↓, CSCs↓, EMT↓, Imm↑, SOD↓, MAPK↓, NF-kB↓, ChemoSen↑, eff↑, toxicity↝, BioAv↑, *Inflam↓, Sepsis↓,
4253- EA,    The effects of Ellagic acid supplementation on neurotrophic, inflammation, and oxidative stress factors, and indoleamine 2, 3-dioxygenase gene expression in multiple sclerosis patients with mild to moderate depressive symptoms: A randomized, triple-blind, placebo-controlled trial
- Human, MS, NA - NA, IBD, NA
*Mood↑, *BDNF↑, *5HT↑, *antiOx↑, *Inflam↓, *AntiCan↑, *QoL↑, *neuroP↑, *cognitive↑, *memory↑,
1607- EA,    Exploring the Potential of Ellagic Acid in Gastrointestinal Cancer Prevention: Recent Advances and Future Directions
- Review, GC, NA
STAT3↓, TumCP↓, Apoptosis↑, NF-kB↓, EMT↓, RadioS↑, antiOx↑, COX1↓, COX2↓, cMyc↓, Snail↓, Twist↓, MMP2↓, P90RSK↓, CDK8↓, PI3K↓, Akt↓, TumCCA↑, Casp8↑, PCNA↓, TGF-β↓, Shh↓, NOTCH↓, IL6↓, ALAT↓, ALP↓, AST↓, VEGF↓, P21↑, *toxicity∅, *Inflam↓, *cardioP↑, *neuroP↑, *hepatoP↑, ROS↑, *NRF2↓, *GSH↑,
1605- EA,    Ellagic Acid and Cancer Hallmarks: Insights from Experimental Evidence
- Review, Var, NA
*BioAv↓, antiOx↓, Inflam↓, TumCP↓, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, P53↑, P21↑, COX2↓, NF-kB↓, Akt↑, NOTCH↓, CDK2↓, CDK6↓, JAK↓, STAT3↓, EGFR↓, p‑ERK↓, p‑Akt↓, p‑STAT3↓, TGF-β↓, SMAD3↓, CDK6↓, Wnt/(β-catenin)↓, Myc↓, survivin↓, CDK8↓, PKCδ↓, tumCV↓, RadioS↑, eff↑, MDM2↓, XIAP↓, p‑RB1↓, PTEN↑, p‑FAK↓, Bax:Bcl2↑, Bcl-xL↓, Mcl-1↓, PUMA↑, NOXA↑, MMP↓, Cyt‑c↑, ROS↑, Ca+2↝, Endoglin↑, Diablo↑, AIF↑, iNOS↓, Casp9↑, Casp3↑, cl‑PARP↑, RadioS↑, Hif1a↓, HO-1↓, HO-2↓, SIRT1↓, selectivity↑, Dose∅, NHE1↓, Glycolysis↓, GlucoseCon↓, lactateProd↓, PDK1?, PDK1?, ECAR↝, COX1↓, Snail↓, Twist↓, cMyc↓, Telomerase↓, angioG↓, MMP2↓, MMP9↓, VEGF↓, Dose↝, PD-L1↓, eff↑, SIRT6↑, DNAdam↓,
5784- EGCG,    Dietary Epicatechin Promotes Survival of Obese Diabetic Mice and Drosophila melanogaster
- in-vivo, Nor, NA
*OS↑, *Inflam↓, *LDL↓, *AntiAge↑, *GSH↑, *SOD↑, *AMPKα↑, *Weight∅,
3224- EGCG,    Epigallocatechin-3-Gallate Prevents Acute Gout by Suppressing NLRP3 Inflammasome Activation and Mitochondrial DNA Synthesis
- in-vitro, Nor, NA
*Casp1↓, *NLRP3↓, *Inflam↓,
3201- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, NA, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *BioAv↝, *BioAv↓, *BioAv↓, *Dose↝, *Half-Life↝, *BioAv↑, *BBB↑, *hepatoP↓, *other↓, *Inflam↓, *NF-kB↓, *AP-1↓, *iNOS↓, *COX2↓, *ROS↓, *RNS↓, *IL8↓, *JAK↓, *PDGFR-BB↓, *IGF-1R↓, *MMP2↓, *P53↓, *NRF2↑, *TNF-α↓, *IL6↓, *E2Fs↑, *SOD1↑, *SOD2↑, Casp3↑, Cyt‑c↑, PARP↑, DNMTs↓, Telomerase↓, Hif1a↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, TumCP↓, MAPK↓, HGF/c-Met↓, TIMP1↑, HDAC↓, MMP9↓, uPA↓, GlutMet↓, ChemoSen↑, chemoP↑,
3205- EGCG,    The Role of Epigallocatechin-3-Gallate in Autophagy and Endoplasmic Reticulum Stress (ERS)-Induced Apoptosis of Human Diseas
- Review, Var, NA - Review, AD, NA
Beclin-1↑, ROS↑, Apoptosis↑, ER Stress↑, *Inflam↓, *cardioP↑, *antiOx↑, *LDL↓, *NF-kB↓, *MPO↓, *glucose↓, *ROS↓, ATG5↑, LC3B↑, MMP↑, lactateProd↓, VEGF↓, Zeb1↑, Wnt↑, IGF-1R↑, Fas↑, Bak↑, BAD↑, TP53↓, Myc↓, Casp8↓, LC3II↑, NOTCH3↓, eff↑, p‑Akt↓, PARP↑, *Cyt‑c↓, *BAX↓, *memory↑, *neuroP↑, *Ca+2?, GRP78/BiP↑, CHOP↑, ATF4↑, Casp3↑, Casp8↑, UPR↑,
3593- EGCG,    Epigallocatechin Gallate (EGCG)
- Review, AD, NA
AntiTum↑, *Inflam↓, *neuroP↑, *Aβ↓, *BioAv↝, cognitive↑,
5487- EP,    High-frequency irreversible electroporation improves survival and immune cell infiltration in rodents with malignant gliomas
- in-vivo, GBM, NA
OS↑, CellMemb↑, Imm↑, Inflam↓, necrosis↑, Pyro↑, eff↑, IL2↑, IL6↑, IL17↑, IFN-γ↓,
6584- EU,    Eurycoma longifolia: an overview on the pharmacological properties for the treatment of common cancer
- Review, Var, NA
*AntiAge↑, *Inflam↓, *antiOx↑, TumCD↑, Bcl-2↓, cl‑Casp7↑, cl‑PARP↑, BAX↑, P53↑, tumCV↓, selectivity↑, *testos↑, *PSA∅,
6574- EU,    Effects of Eurycoma longifolia Jack on chronic cerebral hypoperfusion-induced oxidative damage and memory deficit in rats
- in-vivo, Nor, NA
*cognitive↑, *antiOx↓, *MDA↓, *CRP↓, *neuroP↑, *Inflam↓,
6355- Eug,    Pharmacological and Toxicological Properties of Eugenol
- Review, Var, NA
*Inflam↓, *antiOx↑, *NF-kB↓, *AntiArt↑, *lipid-P↓, *GSH↑, ROS↑, GSH↓, ChemoSen↑, Apoptosis↑, MMP↓, TumCG↓, TumCCA↑,
6383- Eug,    In Vitro Incorporation of Radioiodinated Eugenol on Adenocarcinoma Cell Lines (Caco2, MCF7, and PC3)
- in-vitro, Colon, Caco-2 - in-vitro, BC, MCF-7 - in-vitro, Pca, PC3
antiOx↑, Inflam↓, AntiCan↓, other↝, BioAv↑, other↝,
6381- Eug,    Biological Properties and Prospects for the Application of Eugenol—A Review
- Review, Var, NA
*eff↑, *BioAv↝, *BioAv↝, *BioAv↑, *antiOx↑, *AntiAg↑, *Inflam↓, *AntiBio↑, *MAOA↓, *neuroP↑, *ROS↓, *RNS↓, *eff↑, NF-kB↓, PGE2↓, COX2↓, TumCCA↑, Apoptosis↑, TumCMig↓, TumCI↓, tumCV↓, PI3K↓, Akt↓, MMPs↓, ChemoSen↑, ALDH↓, *Pain↓, *VGSC↓, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *5LO↓, *chemoPv↑,
6379- Eug,    Safety assessment of a standardized polyphenolic extract of clove buds: Subchronic toxicity and mutagenicity studies
- in-vivo, Nor, NA
*toxicity∅, *Dose↑, *Bacteria↓, *Inflam↓, *antiOx↑, *AntiDiabetic↑, *hepatoP↑, *AntiCan↑, *AntiThr↑,
6377- Eug,    Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review
- Review, Var, NA - Review, AD, NA
*Inflam↓, *Bacteria↓, ChemoSen↑, *selectivity↑, ROS⇅, TumCG↓, MMP↓, antiOx⇅, *antiOx↑, *BBB↑, *neuroP↑, *BDNF↑, *Aβ↓, *Ca+2↓, *5LO↓, *MAOA↓, other↑,
6376- Eug,    Preparation, characterization, oral bioavailability, and pharmacodynamic study of eugenol-porous silica solidified powder
- NA, Nor, NA
*Inflam↓, *antiOx↓, *Dose↝, *eff↑,
6389- Eug,    Molecular Insights into the Management of Eugenol's Anticancer Action Against Colon Cancer: A Detailed Review
- Review, Colon, NA
Apoptosis↓, TumCCA↓, Inflam↓, TumMeta↓, BioAv↑, eff↓, Half-Life↓, *ROS↓, *RNS↓, *SOD↓, *Catalase↑, *GSTs↑, *MAOA↓, *neuroP↑, *DNAdam↓, Apoptosis↑, ROS↑, selectivity↑, MMP↓, Cyt‑c↓, Casp3↑, Casp9↑, TumCD↑, BAX↑, BAD↑, APAF1↑, Bcl-2↓, Bcl-xL↓, P53↑, cl‑PARP↑, TumCCA↑, cycD1/CCND1↓, CycB/CCNB1↓, CDK2↓, CDK4↓, P21↑, p27↑, NF-kB↓, COX2↓, PGE2↓, MAPK↓, PI3K↓, Akt↓, mTOR↓, MMPs↓, EMT↓, Snail↓, Slug↓, Zeb1↓, E-cadherin↑, ChemoSen↑,
6386- Eug,    A comprehensive and systematic review on potential anticancer activities of eugenol: From pre-clinical evidence to molecular mechanisms of action
- Review, Var, NA
Apoptosis↑, TumAuto↑, TumCCA↑, Inflam↝, TumCI↓, TumMeta↓, cycD1/CCND1↓, CycB/CCNB1↓, PCNA↓, NF-kB↓, Bcl-2↓, BAX↑, AIF↑, P21↑, P53↑, ChemoSen↑,
6388- Eug,    Eugenol’s anti-cancer properties, its modulation of signalling pathways, and cascades across various cancers: A review
- Review, Var, NA
Dose↝, AntiCan↑, *Inflam↓, *cardioP↑, *neuroP↑, angioG↓, TumMeta↓, *BioAv↑, *eff↑, *toxicity↝, antiNeop↑, TumCCA↑, Apoptosis↑, *antiOx↑, *lipid-P↓, *ROS↓, *SOD↑, *Catalase↑, *GSTs↑, *GPx↑, *iNOS↓, *COX2↓, *IL6↓, *TNF-α↓, *AntiArt↑, *Bacteria↓, TumAuto↑, PI3K↓, Akt↓, FOXO3↝, BAX↑, mTOR↓, NF-kB↓, P53↑, TumCG↓, CSCs↓, CD44↓, EpCAM↓, NOTCH1↓, OCT4↓, Bcl-2↓, PDK1↓, HER2/EBBR2↓, BAD↓, cycD1/CCND1↓, ROS↑, Casp3↑, selectivity↑, MMP2↓, MMP9↓, TIMP1↑, VEGF↓, VEGFR1↓, RECK↑, TIMP2↑, DNAdam↑, MMP↓, Thiols↓, PARP↑, *Pain↓, E2Fs↓, survivin↓,
6325- Eug,    Anticancer Properties of Eugenol: A Review
- Review, Var, NA
*antiOx↑, *AntiCan↑, *Inflam↓, TumCD↑, TumCCA↑, TumCMig↓, TumMeta↓, angioG↓, ChemoSen↑, chemoP↑, *BioAv↝, *BioAv↑, *BioAv↑, *BioAv↑, *Bacteria↓, *ROS↓, *IL6↓, *COX2↓, *TNF-α↓, *lipid-P↓, *SOD1↑, *Catalase↑, *GPx1↑, *GSTs↑, ROS↑, MMP↓, Apoptosis↑, COX2↓, TumCCA↑, E2Fs↓, PI3K↓, Akt↓, MMPs↓, CSCs↓, OCT4↓, CD44↓, EpCAM↓, NOTCH1↓, TumVol↓, Casp3↑, P53↑, cl‑PARP↑, MMP2↓, MMP9↓, TIMP1↑, ALDH↓, NF-kB↓, *toxicity↓,
6324- Eug,    Pharmacodynamic, pharmacokinetic, toxicity, and recent advances in Eugenol's potential benefits against natural and chemical noxious agents: A mechanistic review
- Review, Var, NA
*Inflam↑, *antiOx↑, *Apoptosis↑,
6323- Eug,    Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects
- Review, Var, NA - Review, Arthritis, NA
*AntiCan↑, *AntiDiabetic↑, *cardioP↑, *toxicity↝, *GutMicro↑, *neuroP↑, *BioAv⇅, *BioAv↝, *antiOx↑, *Inflam↑, *AntiArt↑, *TNF-α↓, *IL6↓, *IL10↓, *GSH↑, *GPx↑, *Catalase↑, *MDA↓, *TAC↑, TumCMig↓, TumCI↓, Akt↑, FOXO3↑, Casp3↑, Casp9↑, P21↑, angioG↓, TumCI↓, Apoptosis↑, NF-kB↓, eff↑, eff↑, ChemoSen↑, NA↑, Casp3↑, Casp9↑, *AntiDiabetic↑, *glucose↓, *ROS↓, *Inflam↓, *MDA↓, *GSH↑, *BioAv↑,
1654- FA,    Molecular mechanism of ferulic acid and its derivatives in tumor progression
- Review, Var, NA
AntiCan↑, Inflam↓, RadioS↑, ROS↑, Apoptosis↑, TumCCA↑, TumCMig↑, TumCI↓, angioG↓, ChemoSen↑, ChemoSideEff↓, P53↑, cycD1/CCND1↓, CDK4↓, CDK6↓, TumW↓, miR-34a↑, Bcl-2↓, Casp3↑, BAX↑, β-catenin/ZEB1↓, cMyc↓, Bax:Bcl2↑, SOD↓, GSH↓, LDH↓, ERK↑, eff↑, JAK2↓, STAT6↓, NF-kB↓, PYCR1↓, PI3K↓, Akt↓, mTOR↓, Ki-67↓, VEGF↓, FGFR1↓, EMT↓, CAIX↓, LC3II↑, p62↑, PKM2↓, Glycolysis↓, *BioAv↓,
4070- FA,    Folic Acid Supplementation Mitigates Alzheimer's Disease by Reducing Inflammation: A Randomized Controlled Trial
- Trial, AD, NA
*cognitive↑, *Aβ↓, *TNF-α↓, *Inflam↓,
3781- FA,    Therapeutic potential of ferulic acid and its derivatives in Alzheimer’s disease—A systematic review
- Review, AD, NA
*antiOx↑, *Inflam↓, *BBB↑, *AChE↓, *BChE↓,

Showing Research Papers: 351 to 400 of 871
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 871

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned ⓘ

NA↑, 1,  

Redox & Oxidative Stress ⓘ

antiOx↓, 2,   antiOx↑, 2,   antiOx⇅, 1,   GSH↓, 2,   HO-1↓, 1,   HO-2↓, 1,   PYCR1↓, 1,   ROS↑, 11,   ROS⇅, 1,   SOD↓, 2,   Thiols↓, 1,  

Mitochondria & Bioenergetics ⓘ

AIF↑, 2,   FGFR1↓, 1,   MMP↓, 9,   MMP↑, 1,   mtDam↑, 1,   Raf↓, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   CAIX↓, 1,   cMyc↓, 3,   ECAR↝, 1,   GlucoseCon↓, 1,   GlutMet↓, 1,   Glycolysis↓, 3,   lactateProd↓, 2,   LDH↓, 1,   PDK1?, 2,   PDK1↓, 2,   PKM2↓, 1,   SIRT1↓, 1,  

Cell Death ⓘ

Akt↓, 8,   Akt↑, 2,   p‑Akt↓, 3,   APAF1↑, 2,   Apoptosis↓, 2,   Apoptosis↑, 16,   BAD↓, 1,   BAD↑, 2,   Bak↑, 2,   BAX↑, 10,   Bax:Bcl2↑, 2,   Bcl-2↓, 12,   Bcl-xL↓, 3,   Casp1↑, 1,   Casp3↑, 14,   cl‑Casp3↑, 1,   cl‑Casp7↑, 1,   Casp8↓, 1,   Casp8↑, 3,   Casp9↑, 7,   Cyt‑c↓, 2,   Cyt‑c↑, 4,   Diablo↑, 1,   Fas↑, 1,   HGF/c-Met↓, 1,   iNOS↓, 3,   JNK↓, 1,   MAPK↓, 3,   Mcl-1↓, 1,   MDM2↓, 1,   MOMP↑, 1,   Myc↓, 2,   necrosis↑, 1,   NOXA↑, 1,   p27↑, 1,   PUMA↑, 1,   Pyro↑, 1,   survivin↓, 2,   Telomerase↓, 2,   TumCD↑, 3,  

Kinase & Signal Transduction ⓘ

FOXD3↑, 1,   HER2/EBBR2↓, 1,  

Transcription & Epigenetics ⓘ

Matr↓, 1,   miR-143↑, 1,   other↑, 2,   other↝, 2,   tumCV↓, 6,  

Protein Folding & ER Stress ⓘ

CHOP↑, 2,   eIF2α↑, 1,   ER Stress↑, 2,   GRP78/BiP↑, 1,   PERK↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes ⓘ

ATG5↑, 1,   Beclin-1↑, 1,   LC3B↑, 1,   LC3II↑, 2,   p62↑, 1,   TumAuto↑, 5,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,   DNAdam↑, 3,   DNMTs↓, 1,   P53↑, 9,   PARP↓, 1,   PARP↑, 3,   cl‑PARP↑, 4,   PCNA↓, 2,   SIRT6↑, 1,   TP53↓, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 2,   CDK4↓, 2,   CycB/CCNB1↓, 2,   cycD1/CCND1↓, 6,   cycE/CCNE↓, 1,   E2Fs↓, 2,   P21↓, 1,   P21↑, 5,   p‑RB1↓, 1,   TumCCA↓, 1,   TumCCA↑, 12,  

Proliferation, Differentiation & Cell State ⓘ

4E-BP1↓, 1,   ALDH↓, 3,   CD44↓, 2,   CDK8↓, 2,   CSCs↓, 3,   Diff↑, 1,   EMT↓, 5,   EpCAM↓, 2,   ERK↓, 1,   ERK↑, 1,   p‑ERK↓, 2,   FOXO3↑, 1,   FOXO3↝, 1,   HDAC↓, 1,   IGF-1↓, 1,   IGF-1R↑, 1,   miR-34a↑, 1,   mTOR↓, 4,   NOTCH↓, 2,   NOTCH1↓, 2,   NOTCH3↓, 1,   OCT4↓, 2,   P90RSK↓, 1,   PI3K↓, 9,   PTEN↑, 2,   RAS↓, 1,   Shh↓, 1,   STAT3↓, 2,   p‑STAT3↓, 1,   STAT6↓, 1,   TumCG↓, 6,   Wnt↓, 2,   Wnt↑, 1,   Wnt/(β-catenin)↓, 1,  

Migration ⓘ

Ca+2↝, 1,   E-cadherin↑, 1,   p‑FAK↓, 1,   Ki-67↓, 1,   MMP2↓, 7,   MMP9↓, 7,   MMP9↑, 1,   MMPs↓, 4,   PKCδ↓, 1,   RECK↑, 1,   Slug↓, 1,   SMAD3↓, 1,   Snail↓, 3,   TGF-β↓, 2,   TGF-β↑, 1,   TIMP1↑, 3,   TIMP2↑, 1,   TumCI↓, 9,   TumCMig↓, 10,   TumCMig↑, 1,   TumCP↓, 6,   TumMeta↓, 5,   Twist↓, 2,   uPA↓, 1,   VEGFR1↓, 1,   Zeb1↓, 1,   Zeb1↑, 1,   β-catenin/ZEB1↓, 3,  

Angiogenesis & Vasculature ⓘ

angioG↓, 7,   ATF4↑, 2,   EGFR↓, 1,   Endoglin↑, 1,   Hif1a↓, 2,   VEGF↓, 6,  

Barriers & Transport ⓘ

CellMemb↑, 1,   NHE1↓, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX1↓, 2,   COX2↓, 8,   IFN-γ↓, 1,   IL1↑, 1,   IL17↑, 1,   IL1β↑, 1,   IL2↑, 1,   IL6↓, 1,   IL6↑, 1,   Imm↑, 3,   Inflam↓, 7,   Inflam↝, 1,   JAK↓, 1,   JAK2↓, 1,   NF-kB↓, 13,   PD-L1↓, 1,   PGE2↓, 2,   TLR4↓, 1,   TNF-α↑, 3,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 3,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 3,   BioAv↝, 2,   ChemoSen↑, 13,   DDS↑, 1,   Dose↝, 5,   Dose∅, 1,   eff↓, 2,   eff↑, 11,   Half-Life↓, 1,   Half-Life↝, 1,   RadioS↑, 6,   selectivity↑, 7,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   EGFR↓, 1,   HER2/EBBR2↓, 1,   IL6↓, 1,   IL6↑, 1,   Ki-67↓, 1,   LDH↓, 1,   Myc↓, 2,   PD-L1↓, 1,   TP53↓, 1,  

Functional Outcomes ⓘ

AntiCan↓, 1,   AntiCan↑, 3,   antiNeop↑, 1,   AntiTum↑, 4,   chemoP↑, 4,   ChemoSideEff↓, 2,   cognitive↑, 1,   OS↑, 1,   QoL↑, 1,   Risk↓, 1,   toxicity↓, 1,   toxicity↝, 1,   TumVol↓, 2,   TumW↓, 1,  

Infection & Microbiome ⓘ

Sepsis↓, 1,  
Total Targets: 242

Pathway results for Effect on Normal Cells:


NA, unassigned ⓘ

AntiArt↑, 3,   AntiBio↑, 1,   diuretic↑, 2,  

Redox & Oxidative Stress ⓘ

antiOx↓, 2,   antiOx↑, 21,   Catalase↑, 7,   GPx↑, 4,   GPx1↑, 1,   GSH↑, 8,   GSTs↑, 3,   HO-1↑, 1,   lipid-P↓, 6,   MDA↓, 5,   MPO↓, 1,   NRF2↓, 1,   NRF2↑, 3,   RNS↓, 3,   ROS↓, 16,   SOD↓, 1,   SOD↑, 4,   SOD1↑, 2,   SOD2↑, 1,   TAC↑, 1,  

Mitochondria & Bioenergetics ⓘ

Insulin↓, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis ⓘ

adiP↑, 1,   ALAT↓, 2,   AMPK↑, 1,   BUN↓, 1,   glucose↓, 4,   LDL↓, 3,  

Cell Death ⓘ

Apoptosis↓, 1,   Apoptosis↑, 1,   BAX↓, 1,   Casp1↓, 1,   Casp3↓, 1,   proCasp3↓, 1,   Casp9↓, 1,   Cyt‑c↓, 2,   iNOS↓, 4,  

Kinase & Signal Transduction ⓘ

AMPKα↑, 1,  

Transcription & Epigenetics ⓘ

AntiThr↑, 2,   other↓, 1,   other↑, 1,   other↝, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 3,   P53↓, 1,  

Cell Cycle & Senescence ⓘ

E2Fs↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

IGF-1R↓, 1,   mTOR↓, 1,   RAS↓, 1,   VGSC↓, 1,  

Migration ⓘ

5LO↓, 3,   AntiAg↑, 2,   AP-1↓, 2,   Ca+2?, 1,   Ca+2↓, 1,   MMP2↓, 2,   MMP3↓, 1,   MMP9↓, 1,   MMPs↑, 1,   TGF-β1↓, 1,   TIMP1↑, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   NO↓, 2,   PDGFR-BB↓, 1,   VEGF↓, 1,  

Barriers & Transport ⓘ

BBB↑, 3,   GastroP↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 6,   CRP↓, 1,   IL1↓, 1,   IL10↓, 1,   IL12↓, 1,   IL1β↓, 2,   IL2↑, 1,   IL6↓, 9,   IL8↓, 2,   Imm↑, 4,   Inflam↓, 41,   Inflam↑, 2,   JAK↓, 1,   MCP1↓, 1,   NF-kB↓, 7,   PGE2↓, 2,   PSA∅, 1,   TLR4↓, 1,   TNF-α↓, 12,  

Synaptic & Neurotransmission ⓘ

5HT↑, 1,   AChE↓, 2,   BChE↓, 2,   BDNF↑, 2,   MAOA↓, 3,  

Protein Aggregation ⓘ

Aβ↓, 4,   NLRP3↓, 2,  

Hormonal & Nuclear Receptors ⓘ

testos↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 4,   BioAv↑, 8,   BioAv⇅, 1,   BioAv↝, 6,   BioEnh↑, 1,   Dose↑, 1,   Dose↝, 4,   eff↑, 6,   Half-Life↝, 1,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 2,   Albumin↝, 1,   AST↓, 1,   BP↓, 2,   creat↓, 2,   CRP↓, 1,   GutMicro↑, 2,   IL6↓, 9,   PSA∅, 1,  

Functional Outcomes ⓘ

AntiAge↑, 2,   AntiCan↑, 6,   AntiDiabetic↑, 8,   AntiTum↑, 1,   cardioP↑, 7,   chemoP↑, 1,   chemoPv↑, 3,   cognitive↑, 5,   hepatoP↓, 1,   hepatoP↑, 5,   memory↑, 3,   Mood↑, 1,   neuroP↑, 16,   OS↑, 2,   Pain↓, 2,   QoL↑, 2,   RenoP↑, 3,   toxicity?, 1,   toxicity↓, 3,   toxicity↝, 2,   toxicity∅, 3,   Weight∅, 1,   Wound Healing↑, 1,  

Infection & Microbiome ⓘ

Bacteria↓, 7,   Sepsis↓, 1,  
Total Targets: 140

Scientific Paper Hit Count for: Inflam, inflammation
40 Curcumin
30 Silymarin (Milk Thistle) silibinin
30 Quercetin
28 Thymoquinone
27 Hydrogen Gas
27 Magnetic Fields
23 Resveratrol
18 Alpha-Lipoic-Acid
18 Berberine
18 Selenium NanoParticles
17 Lycopene
17 Rosmarinic acid
16 Ashwagandha(Withaferin A)
15 Capsaicin
15 Carvacrol
15 Sulforaphane (mainly Broccoli)
15 Urolithin
14 Propolis -bee glue
13 Silver-NanoParticles
13 Beta-Caryophyllene
12 Apigenin (mainly Parsley)
12 Baicalein
12 Chlorogenic acid
12 Chrysin
12 Eugenol
11 Ferulic acid
11 Fisetin
11 Honokiol
10 Radiotherapy/Radiation
10 Cinnamon
10 Crocetin
10 Dandelion Root
10 Pterostilbene
9 Selenite (Sodium)
9 Boron
8 Astaxanthin
8 Boswellia (frankincense)
8 α-Bisabolol / Chamomile oil
8 Chemotherapy
8 Piperlongumine
8 Vitamin C (Ascorbic Acid)
8 Shikonin
7 Betulinic acid
7 Vitamin B3,Niacin
7 Butyrate
7 D-limonene
6 1,8-Cineole
6 Allicin (mainly Garlic)
6 Artemisinin
6 Thymol-Thymus vulgaris
6 EGCG (Epigallocatechin Gallate)
6 Magnolol
6 Piperine
6 Rutin
5 Aspirin
5 Caffeic acid
5 Celastrol
5 chitosan
5 Chocolate
5 Coenzyme Q10
5 Shilajit/Fulvic Acid
5 Luteolin
5 Magnetic Field Rotating
5 Ursolic acid
4 Bacopa monnieri
4 Cisplatin
4 Caffeic Acid Phenethyl Ester (CAPE)
4 Carvone
4 Geraniol
4 Ginger/6-Shogaol/Gingerol
4 Moringa oleifera
4 nicotinamide adenine dinucleotide
4 Taurine
4 Vitamin B5,Pantothenic Acid
4 Vitamin D3
4 Vitamin K2
3 Anethole/trans-Anethole
3 Baicalin
3 Biochanin A
3 Folic Acid, Vit B9
3 Bromelain
3 doxorubicin
3 Carnosine
3 Hydroxycinnamic-acid
3 Spermidine
3 Cucurbitacin
3 Ellagic acid
3 HydroxyCitric Acid
3 HydroxyTyrosol
3 Methylsulfonylmethane
3 Nimbolide
3 α-Santalol/Sandalwood oil
3 Sulfasalazine
3 Vitamin B1/Thiamine
2 Anthocyanins
2 alpha Linolenic acid
2 Fennel Oil/Foeniculum vulgare
2 Melatonin
2 Vitamin B12
2 brusatol
2 borneol
2 Cat’s Claw
2 Celecoxib
2 Chlorophyllin
2 Choline
2 Selenium
2 Vitamin E
2 Galantamine
2 Huperzine A/Huperzia serrata
2 Lecithin
2 diet Short Term Fasting
2 Eurycomanone
2 Exercise
2 Ginkgo biloba
2 Ginseng
2 Orlistat
2 Potassium
2 Lutein
2 Methyl salicylate / Sweet Birch oil
2 Mushroom Lion’s Mane
2 Naringin
2 Oleocanthal
2 Phenylbutyrate
2 Phenethyl isothiocyanate
2 Phosphatidylserine
2 Salvia officinalis
2 Shankhpushpi
2 Salvia miltiorrhiza
2 Aflavin-3,3′-digallate
2 Turmerones
1 2-DeoxyGlucose
1 5-Hydroxytryptophan
1 Astragalus
1 Acetyl-l-carnitine
1 Aloe anthraquinones
1 beta-glucans
1 xanthohumol
1 Cannabidiol
1 beta-carotene(VitA)
1 Vitamin B6,pyridoxine
1 Bifidobacterium
1 Brucea javanica
1 Bruteridin(bergamot juice)
1 Paclitaxel
1 Carnosic acid
1 Cannabichromene
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Prebiotic
1 Carica papaya leaf extract
1 Calorie Restriction Mimetics
1 Copper and Cu NanoParticles
1 Rivastigmine
1 Disulfiram
1 immunotherapy
1 Electrical Pulses
1 Ascorbyl Palmitate
1 Flickering Light Stimulation
1 Iron
1 Gallic acid
1 Germacranolide
1 γ-linolenic acid (Borage Oil)
1 hydrogen sulfide
1 Juglone
1 Licorice
1 Linalool
1 Zeaxanthin
1 5-fluorouracil
1 MCToil
1 Metformin
1 Oleuropein
1 Peppermint
1 Propyl gallate
1 Psoralidin
1 Parthenolide
1 EMF
1 Radio Frequency
1 Aromatherapy
1 Gold NanoParticles
1 Sesame seeds and Oil
1 Silicic Acid
1 Terpinen-4-ol / Tea Tree Oil
1 cetuximab
1 Vitamin A, Retinoic Acid
1 Vitamin B2,Riboflavin
1 probiotics
1 Zinc
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:953  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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