| Source: |
| Type: type of cell death |
| Situation in which a cell actively pursues a course toward death upon receiving certain stimuli. Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die. |
| 6461- | 1,8-Cin, | 1,8-cineole (eucalyptol): A versatile phytochemical with therapeutic applications across multiple diseases |
| - | Review, | AD, | NA | - | Review, | Var, | NA |
| 6476- | 1,8-Cin, | Specific induction of apoptosis by 1,8-cineole in two human leukemia cell lines, but not a in human stomach cancer cell line |
| - | in-vitro, | AML, | NA |
| 6467- | 1,8-Cin, | Evaluation of in vitro anticancer activity of 1,8-Cineole-containing n-hexane extract of Callistemon citrinus (Curtis) Skeels plant and its apoptotic potential |
| - | in-vitro, | Melanoma, | A431 | - | in-vitro, | OS, | MG63 | - | in-vitro, | Nor, | HaCaT |
| 6463- | 1,8-Cin, | Antitumor effect of 1, 8-cineole against colon cancer |
| - | vitro+vivo, | Colon, | HCT116 |
| 2432- | 2DG, | Inhibition of glycolytic enzyme hexokinase II (HK2) suppresses lung tumor growth |
| - | in-vitro, | Lung, | H23 | - | in-vitro, | Lung, | KP2 | - | in-vivo, | NA, | NA |
| 2327- | 2DG, | 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents |
| - | Review, | Var, | NA |
| 9018- | 3BP, | C-Phycocyanin exerts anti-cancer effects via the MAPK signaling pathway in MDA-MB-231 cells |
| - | in-vitro, | BC, | MDA-MB-231 |
| 7857- | 3BP, | A Mechanism of Isoorientin-Induced Apoptosis and Migration Inhibition in Gastric Cancer AGS Cells |
| - | in-vitro, | GC, | AGS |
| 5263- | 3BP, | CET, | 3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis |
| - | in-vitro, | CRC, | DLD1 | - | NA, | NA, | HCT116 |
| 5269- | 3BP, | The anti-metabolite KAT/3BP has in vitro and in vivo anti-tumor activity in lymphoma models. |
| - | in-vitro, | HCC, | NA |
| 5265- | 3BP, | KAT/3BP: A Metabolism-Targeting Agent with Single and Combination Activity in Aggressive B-Cell Lymphomas |
| - | Review, | lymphoma, | NA |
| 5266- | 3BP, | 3-bromopyruvate-based agent KAT-101 |
| - | Review, | Var, | NA |
| 5270- | 5-ALA, | PDT, | 5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy |
| - | Review, | Var, | NA |
| 3453- | 5-ALA, | The heme precursor 5-aminolevulinic acid disrupts the Warburg effect in tumor cells and induces caspase-dependent apoptosis |
| - | in-vitro, | Lung, | A549 |
| - | in-vitro, | CRC, | NA |
| 5296- | 5-HTP, | Serotonergic Regulation in Alzheimer’s Disease |
| - | Review, | AD, | NA |
| 7842- | AAL, | ISQ, | RT, | Annona atemoya leaf extract ameliorates cognitive impairment in amyloid-β injected Alzheimer's disease-like mouse model |
| - | in-vivo, | AD, | HT22 |
| 5472- | AF, | Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion |
| - | in-vitro, | Cerv, | HeLa |
| 5459- | AF, | Auranofin Induces Lethality Driven by Reactive Oxygen Species in High-Grade Serous Ovarian Cancer Cells |
| - | in-vitro, | Ovarian, | NA |
| 5460- | AF, | Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species |
| - | vitro+vivo, | Var, | 4T1 |
| 5462- | AF, | Repurposing Auranofin for Oncology and Beyond: A Brief Overview of Clinical Trials as Mono- and Combination Therapy |
| - | Review, | Var, | NA |
| 5463- | AF, | Will Auranofin Become a Golden New Treatment Against COVID-19? |
| - | Review, | Covid, | NA |
| 5468- | AF, | The gold complex auranofin: new perspectives for cancer therapy |
| - | Review, | Var, | NA |
| 1900- | AF, | Potential Anticancer Activity of Auranofin |
| - | Review, | Var, | NA |
| 1334- | AG, | Astragalus membranaceus: A Review of Its Antitumor Effects on Non-Small Cell Lung Cancer |
| - | Review, | NSCLC, | NA |
| 1338- | AG, | The Modulatory Properties of Astragalus membranaceus Treatment on Triple-Negative Breast Cancer: An Integrated Pharmacological Method |
| - | in-vitro, | BC, | NA |
| 1295- | AG, | Cisplatin, | Chemosensitizing Effect of Astragalus Polysaccharides on Nasopharyngeal Carcinoma Cells by Inducing Apoptosis and Modulating Expression of Bax/Bcl-2 Ratio and Caspases |
| - | in-vivo, | Laryn, | NA |
| 1000- | AG, | 5-FU, | Characterization and anti-tumor bioactivity of astragalus polysaccharides by immunomodulation |
| - | vitro+vivo, | BC, | 4T1 |
| 5431- | AG, | Advances in research on the anti-tumor mechanism of Astragalus polysaccharides |
| - | Review, | Var, | NA |
| 5434- | AG, | Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview |
| - | Review, | Liver, | NA |
| 5239- | AgNPs, | NOX4- and Nrf2-mediated oxidative stress induced by silver nanoparticles in vascular endothelial cells |
| - | in-vitro, | Nor, | HUVECs |
| 4551- | AgNPs, | FBZ, | Ångstrom-Scale Silver Particles as a Promising Agent for Low-Toxicity Broad-Spectrum Potent Anticancer Therapy |
| - | in-vivo, | Lung, | NA |
| 4563- | AgNPs, | Rad, | Silver nanoparticles enhance neutron radiation sensitivity in cancer cells: An in vitro study |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | Ovarian, | SKOV3 | - | in-vitro, | GBM, | U87MG | - | in-vitro, | Melanoma, | A431 |
| 4561- | AgNPs, | VitC, | Cellular Effects Nanosilver on Cancer and Non-cancer Cells: Potential Environmental and Human Health Impacts |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Nor, | HEK293 |
| 4559- | AgNPs, | Anticancer activity of biogenerated silver nanoparticles: an integrated proteomic investigation |
| - | in-vitro, | BC, | SkBr3 | - | in-vitro, | CRC, | HT-29 | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Colon, | Caco-2 |
| 4555- | AgNPs, | Silver nanoparticles from Dendropanax morbifera Léveille inhibit cell migration, induce apoptosis, and increase generation of reactive oxygen species in A549 lung cancer cells |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Liver, | HepG2 |
| 4552- | AgNPs, | ART/DHA, | Green synthesis of silver nanoparticles using Artemisia turcomanica leaf extract and the study of anti-cancer effect and apoptosis induction on gastric cancer cell line (AGS) |
| - | in-vitro, | GC, | AGS |
| 4564- | AgNPs, | GoldNP, | Cu, | Chemo, | PDT | Cytotoxicity and targeted drug delivery of green synthesized metallic nanoparticles against oral Cancer: A review |
| - | Review, | Var, | NA |
| 4546- | AgNPs, | Chapter 2 - Silver nanoparticles in cancer therapy |
| - | Study, | Var, | NA |
| 4542- | AgNPs, | Silver Nanoparticles (AgNPs): Comprehensive Insights into Bio/Synthesis, Key Influencing Factors, Multifaceted Applications, and Toxicity─A 2024 Update |
| - | Review, | Var, | NA |
| 5145- | AgNPs, | Silver nanoparticles induce irremediable endoplasmic reticulum stress leading to unfolded protein response dependent apoptosis in breast cancer cells |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | T47D |
| - | in-vitro, | CRC, | HCT116 |
| 5142- | AgNPs, | Biosynthesized Protein-Capped Silver Nanoparticles Induce ROS-Dependent Proapoptotic Signals and Prosurvival Autophagy in Cancer Cells |
| - | in-vitro, | CRC, | HUH7 |
| 4398- | AgNPs, | Induction of apoptosis in cancer cells at low silver nanoparticle concentrations using chitosan nanocarrier |
| - | in-vitro, | Colon, | HT29 |
| 4394- | AgNPs, | Silver nanoparticles provoke apoptosis of Dalton's ascites lymphoma in vivo by mitochondria dependent and independent pathways |
| - | in-vivo, | lymphoma, | NA |
| 4403- | AgNPs, | Silver Nanoparticles Decorated UiO-66-NH2 Metal-Organic Framework for Combination Therapy in Cancer Treatment |
| - | in-vitro, | GBM, | U251 | - | in-vitro, | GBM, | U87MG | - | in-vitro, | GBM, | GL26 | - | in-vitro, | Cerv, | HeLa | - | in-vitro, | CRC, | RKO |
| 4391- | AgNPs, | Silver Nanoparticles Induce Apoptosis in HepG2 Cells through Particle-Specific Effects on Mitochondria |
| - | in-vitro, | Liver, | HepG2 |
| 4388- | AgNPs, | Differential Cytotoxic Potential of Silver Nanoparticles in Human Ovarian Cancer Cells and Ovarian Cancer Stem Cells |
| - | in-vitro, | Cerv, | NA |
| 4383- | AgNPs, | Exploring the Potentials of Silver Nanoparticles in Overcoming Cisplatin Resistance in Lung Adenocarcinoma: Insights from Proteomic and Xenograft Mice Studies |
| - | in-vitro, | Lung, | A549 | - | in-vivo, | Lung, | A549 |
| 4417- | AgNPs, | Caffeine-boosted silver nanoparticles target breast cancer cells by triggering oxidative stress, inflammation, and apoptotic pathways |
| - | in-vitro, | BC, | MDA-MB-231 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
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